Clinical trials: Disorder of Vein
Thrombosis, Pulmonary Embolism
Association of Anti-factor Xa Activity With Venous Thromboembolism in Critically Ill Patients
The goal of this observational study is to analyse the association between anti-factor Xa activity (antiXa) and the occurence of venous thromboembolism (VTE; either deep vein thrombosis and/or pulmonary embolism) in critically…
- Conditions
- Thrombosis, Pulmonary Embolism, Enoxaparin
- Trial name
- AntiXa-ICU (NCT06357403)
- Testing
- Anti-factor Xa activity calibrated for enoxaparin
- Where
- 3 sites in Austria
- Volunteers
- 1,300 people
- Sponsor
- Medical University of Vienna
Healthy Volunteers, Heart Failure
A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy Participants
This study is being done to understand how much of the medicine (CDR132L) enters the bloodstream after injection under the skin compared to injection into a vein in healthy people.
- Trial name
- NCT07656454
- Testing
- CDR132L (i.v.), CDR132L (s.c.)
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabetic Foot, Venous Ulcer
Adipose Derived Regenerative Cellular Therapy of Chronic Wounds
Our study aims to explore the effects of Adipose Derived Stem Cells (ASCs) on chronic wounds.
- Conditions
- Diabetic Foot, Venous Ulcer, Pressure Ulcer
- Trial name
- NCT02092870
- Testing
- Adipose derived stem cells
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Tower Outpatient Surgical Center
Venous Ulcer
Shock Wave Versus Low Level Laser on Chronic Venous Ulcer
To find out the difference in the effect of shock wave therapy and low level laser therapy on venous ulcer patient As regards the following outcomes; 1.
- Trial name
- NCT06756386
- Testing
- extra corporeal shock wave therapy (ESWT ), Low Level Laser Therapy, conservative treatments
- Volunteers
- 45 people
- Sponsor
- Beni-Suef University
Atrial Fibrillation
The Contact PVI Study: Use of Tissue Contact Data to Guide Atrial Fibrillation Ablation
This study aims to investigate the benefit of a new impedance-based computer software application during routine catheter ablation for atrial fibrillation, to see if this information improves short and long term electrical…
- Trial name
- NCT01629056
- Testing
- ablation, RF ablation
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- Oxford University Hospitals NHS Trust
Feeding Intolerance, Necrotising Enterocolitis Neonatal
The Effect of Umbilical Vein Catheterization on Splanchnic Oxygenation in Preterm Infants
Objectives: This study aimed to assess the impact of umbilical vein catheter (UVC) placement on splanchnic oxygenation in preterm infants.
- Trial name
- NCT06768203
- Testing
- umbilical vein catheterization, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Eskisehir Osmangazi University
Venous Leg Ulcer
HM242-Gel vs Comparator
The primary objective of the study is to demonstrate that the HM242-Gel performs at least comparably to INTRASITE Gel with regard to wound healing.
- Trial name
- NCT04902651
- Testing
- HM242-Gel, Intrasite Gel
- Where
- 3 sites in Czechia, Slovakia
- Volunteers
- 73 people
- Sponsor
- B. Braun Ltd. Centre of Excellence Infection Control
Neoplasms, Surgery--Complications
Resection of the Inferior Vena Cava Due to Tumor Involvement
The involvement of the inferior vena cava (IVC) in advanced abdominal tumors is a surgical challenge, given the high postoperative morbidity and poor long-term prognosis.
- Conditions
- Neoplasms, Surgery--Complications, Vascular Diseases, Vein Disease
- Trial name
- CAVARESECT (NCT04154761)
- Testing
- Resection of inferior vena cava and reconstruction
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- Hospital Universitario Infanta Cristina
Deep Venous Thrombosis
Simplification of the Diagnosis of Deep Vein Thrombosis
Prospective cohort study aimed at simplifying the diagnostic approach to symptomatic patients with the clinical suspicion of deep vein thrombosis (DVT) of the lower extremities.
- Trial name
- PALLADIO (NCT01412242)
- Testing
- Extensive search for isolated calf DVT
- Where
- Italy
- Volunteers
- 1,100 people
- Sponsor
- University of Padova
Deep Vein Thrombosis, Post-thrombotic Syndrome
Elastic Compression Stockings for Prevention of Post-thrombotic Syndrome
Post thrombotic syndrome (PTS) is a frequent and burdensome complication of proximal deep-vein thrombosis.Therapeutic options for PTS are limited and mainly rely on its prevention.
- Trial name
- CELEST (NCT01578122)
- Testing
- 25mmHg ECS, 35 mmHg ECS
- Where
- 57 sites in France
- Volunteers
- 350 people
- Sponsor
- Laboratoires Innothera
DVT, Osteoarthritis
Does Thinning the Blood During Surgery Prevent Blood Clots Following Total Knee Replacement Surgery
The goal of this study is to prevent blood clots from forming during surgery and a few days after total knee replacement surgery.
- Trial name
- NCT00253851
- Testing
- unfractionated heparin
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
Venous Leg Ulcers, Venous Leg Ulcers (VLUs)
Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-Heal VLUs
The purpose of this study is to evaluate the efficacy of two dehydrated human umbilical cord-based medical devices, also defined as Cellular, Acellular, Matrix-like Products/skin substitutes, plus SOC versus SOC alone in…
- Conditions
- Venous Leg Ulcers, Venous Leg Ulcers (VLUs), Venous Leg, Leg Ulcers
- Trial name
- CORDSTIM-VLU (NCT07449988)
- Testing
- Standard of Care (SOC), Corplex P, Theracor
- Volunteers
- 272 people
- Sponsor
- StimLabs
Persistent Atrial Fibrillation
Persistent Atrial Fibrillation Cryoballoon Ablation
Patients with persistent irregular heartbeats also called persistent atrial fibrillation usually have a lower probability of curing their arrhythmia with ablation with heat called radiofrequency then those with paroxysmal atrial…
- Trial name
- PAFCA (NCT02166723)
- Testing
- Cryoballoon Ablation
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Staten Island University Hospital
Paroxysmal Atrial Fibrillation
REVOLUTION (WFCC-133) - Treatment of Paroxysmal Atrial Fibrillation
The purpose of this study is to assess the safety and effectiveness of the Circular and Crescent Mapping and Ablation catheters and the workflow of the Multi-Electrode Irrigated Pulmonary Vein Isolation System when used for the…
- Trial name
- REVOLUTION (NCT01353586)
- Testing
- nMARQ™ System
- Where
- 8 sites in Belgium, Czechia and 4 more
- Volunteers
- 186 people
- Sponsor
- Biosense Webster, Inc.
Pulmonary Embolism, Deep Vein Thrombosis
Angel® Catheter Early Feasibility Clinical Study
The primary objective of this clinical trial is to obtain initial insights into the safety of the Angel® Catheter in critically ill subjects with high risk of venous thromboembolism (VTE) disease AND who are not receiving…
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Venous Thromboembolism
- Trial name
- NCT01847196
- Testing
- Angel® Catheter
- Where
- 4 sites in United States
- Volunteers
- 6 people
- Sponsor
- BiO2 Medical
Cirrhosis, Hepatic Encephalopathy
Effect of Brief Dietary Intervention on Ammonia Levels
Study the impact of differing meal contents on venous ammonia levels over time in patients with cirrhosis. Patients will be given specific meals and venous ammonia analyzed over time after those meals.
- Trial name
- NCT05376488
- Testing
- One meal
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Acute Coronary Syndrome, Chronic Coronary Syndrome
Common Femoral Vein-to-Artery Diameter Ratio for Detection of Elevated LVEDP
This prospective cross-sectional diagnostic accuracy study enrolled patients undergoing coronary angiography and left heart catheterization at Burapha University Hospital, Thailand.
- Conditions
- Acute Coronary Syndrome, Chronic Coronary Syndrome, Heart Failure
- Trial name
- NCT07866859
- Testing
- Ultrasound Measurement of Common Femoral Vein-to-Artery Diameter Ratio
- Where
- Thailand
- Volunteers
- 105 people
- Sponsor
- Burapha University
Diabetic Foot Ulcers, Venous Ulcers
Registry Trial of the Effectiveness of Platelet Rich Plasma for Chronic Non-Healing Wounds
This study will examine differences in the process of wound-healing in patients treated with platelet rich plasma (a concentration of proteins derived from a patients own blood) applied to the wound as a gel; injected into the…
- Conditions
- Diabetic Foot Ulcers, Venous Ulcers, Pressure Ulcers
- Trial name
- CMS (NCT02071979)
- Testing
- Autologous PRP Gel, Autologous PRP Injections, Autologous PRP Gel plus PRP Injections
- Where
- 6 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Arteriocyte, Inc.
Thrombocytopenia Related to Chronic Liver Disease, Anticoagulation Treatment
Safety of Anticoagulation Therapy in Cirrhotic Patients With PVT and Severe Thrombocytopenia
Severe thrombocytopenia (platelet count ≤ 50 × 10^9/L) can significantly increase the risk of bleeding. Safety of Anticoagulation (AC) therapy in cirrhotic patients with portal vein thrombosis (PVT) and severe thrombocytopenia is…
- Conditions
- Thrombocytopenia Related to Chronic Liver Disease, Anticoagulation Treatment, Safety, Portal Vein Thrombosis
- Trial name
- AC in PVT (NCT07885969)
- Testing
- Anticoagulation Therapy
- Where
- China
- Volunteers
- 304 people
- Sponsor
- Qilu Hospital of Shandong University
Advanced Cancers, Malignant Pleural Effusions
Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for Pleurodesis
The goal of this clinical research study is to compare indwelling pleural catheters (IPC) in combination with saline (the current standard of care) versus IPC in combination with doxycycline as treatment for pleural effusions.
- Trial name
- NCT02623959
- Testing
- Questionnaires, Fentanyl Patch, Fentanyl (IV)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
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