Clinical trials: Disorder of the Lower Urinary Tract
Overactive Bladder
Interventional Clinical Trial in Patients in Overactive Bladder With Nocturia in Women
The purpose of the trial is to investigate the efficacy of combining tolterodine and desmopressin compared with tolterodine monotherapy in the treatment of women with overactive bladder with nocturia in terms of reduction of…
- Trial name
- NCT01729819
- Testing
- Tolterodine tartrate extended release capsules, Desmopressin orally disintegrating tablets
- Where
- 24 sites in United States
- Volunteers
- 106 people
- Sponsor
- Ferring Pharmaceuticals
BPH (Benign Prostatic Hyperplasia), Lower Urinary Tract Symptoms (LUTS)
Safety and Effectiveness Study of the Zenflow Spring System
Evaluate the safety and effectiveness of the Zenflow Spring System in relieving LUTS associated with BPH.
- Trial name
- BREEZE (NCT04987138)
- Testing
- Zenflow Spring System
- Where
- 7 sites in United States
- Volunteers
- 279 people
- Sponsor
- Zenflow, Inc.
Relapsing-Remitting Multiple Sclerosis, Urinary Incontinence
Guided Versus Non-guided Pelvic Floor Exercises for Urinary Incontinence in Relapsing-Remitting Multiple Sclerosis
The aim of the study is to evaluate the effectiveness of guided versus non guided pelvic floor exercises for urinary incontinence in patients with Relapsing-Remitting Multiple Sclerosis
- Trial name
- NCT03000647
- Testing
- Pelvic floor exercises guided by a physiotherapist, Non guided pelvic floor exercises
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Refractory Overactive Bladder
Vaginal Electrical Stimulation Versus Neuromodulation
This prospective study compares quality of life measures of patients with refractory overactive bladder, between two modes of neuromodulation: vaginal electrical stimulation (Group A) and sacral nerve stimulation (Group B).
- Trial name
- Estim (NCT01525485)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Oklahoma
Fall, Multiple Sclerosis
Is the Severity of Urinary Disorders Related to Falls in People With Multiple Sclerosis
Falls are a common problem in people with multiple sclerosis (PwMS) and can lead to severe consequences (trauma, fear of falling, reduction of social activities).
- Conditions
- Fall, Multiple Sclerosis, Lower Urinary Tract Symptoms
- Trial name
- NCT04338646
- Testing
- Clinical tests
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Gérard Amarenco
Recurrent UTIs, Recurrent Urinary Tract Infections
A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections
A randomized, double-blind, placebo-controlled, 12-month study to determine the effectiveness of D-mannose (2g daily) supplementation in rUTI (recurrent urinary tract infection) prevention in post-menopausal women.
- Conditions
- Recurrent UTIs, Recurrent Urinary Tract Infections, Recurrent Urinary Tract Infections in Women, Recurrent Urinary Tract Infection
- Trial name
- DmannoseRCT (NCT06940622)
- Testing
- D-Mannose
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Texas Southwestern Medical Center
Overactive Bladder (OAB), Over Active Bladder
A Prospective Evaluation of a Prescription Digital Therapeutic for Treatment of Overactive Bladder in Women: The RiSolve Trial
The RiSolve Trial is a prospective, single-arm, post-market clinical investigation designed to evaluate the effectiveness, usability, and safety of a prescription digital therapeutic (PDTx) for women suffering from overactive…
- Trial name
- NCT07206446
- Testing
- RiSolve
- Where
- Ireland
- Volunteers
- 46 people
- Sponsor
- University of Galway
Urinary Incontinence
A Telehealth-delivered Physical Therapy Program for Postmenopausal Women with Urinary Incontinence
Postmenopausal women frequently report physical (hot flushes, night sweat, insomnia, vaginal dryness, sexual dysfunction, urinary incontinence, reduced fitness level, osteoporotic symptoms, sarcopenia, decreased fat free mass…
- Trial name
- NCT05970796
- Testing
- Pelvic floor muscle training
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- National Taiwan University
Intraoperative Floppy Iris Syndrome, Cataract
Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome (IFIS) is a potentially serious cataract surgery complication. IFIS is most commonly associated with the chronic use of tamsulosin and other alpha1-adrenergic receptor antagonists prescribed in…
- Conditions
- Intraoperative Floppy Iris Syndrome, Cataract, Age-related Cataract, Adrenergic Receptor Antagonist Adverse Reaction
- Trial name
- NCT06266962
- Testing
- 1% Atropine drops, Epinephrine
- Where
- Czechia
- Volunteers
- 164 people
- Sponsor
- University Hospital Olomouc
Stress Urinary Incontinence
Assessing the Utility of Prophylactic Antibiotics at Time of Urethral Bulking Using Bulkamid (Bulkamid Study)
The primary aim of this study is to assess the utility of prophylactic oral antibiotics at time of Bulkamid transurethral bulking to reduce the incidence of urinary tract infection (UTI) in the immediate postoperative period.
- Trial name
- NCT06706362
- Testing
- Bactrim or Macrobid
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Ohio State University
Stress Urinary Incontinence, Urethral Intrinsic Sphincter Deficiency
A New Therapeutic Strategy for Urethral Sphincter Insufficiency
Stress urinary incontinence is a frequent condition that can be caused by urethral sphincter insufficiency and results in a dramatic deterioration of the quality of life.
- Trial name
- NCT00472069
- Testing
- transplantation of the squeletic muscular cells
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Overactive Bladder
Arabic Translation and Validation of the (Overactive Bladder Symptom Score) OABSS
The English version of the Overactive Bladder Symptom Score (OABSS) questionnaire was translated to Arabic language. The questionnaire was validated by comparing the response to the questionnaire in a patient with Overactive…
- Trial name
- NCT04309890
- Testing
- Arabic version of the Overactive Bladder Symptom Score Questionnaire
- Where
- Jordan
- Volunteers
- 235 people
- Sponsor
- Mutah University
Dyspareunia, Urinary Incontinence
The Influence of Prepartum Perineal Training With the Epi-No Device on Pelvic Floor Function.
Perineal injury is the most common maternal obstetric complication associated with vaginal delivery (1). It is estimated that perineal lacerations of first and second degree occur in 38% of spontaneous vaginal deliveries in…
- Conditions
- Dyspareunia, Urinary Incontinence, Perineal Tear, Perineal Injury
- Trial name
- NCT05282160
- Testing
- Epino
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Universidade Estadual de Londrina
Genitourinary System; Disorder, Female, Burning Vagina
Laser Therapy for Treatment of Urogenital Symptoms in Women
This is a prospective observational study of women undergoing vaginal treatment with the fractional carbon dioxide (fCO2) laser for various urogenital symptoms.
- Conditions
- Genitourinary System; Disorder, Female, Burning Vagina, Dyspareunia, Irritation; Vagina
- Trial name
- NCT03681678
- Testing
- fCO2 Laser Therapy Group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Corewell Health East
Urinary Incontinence, Medical Device Discomfort
Tolerance, Use and Performance of the PEASY Urine Collection Device in Hospitalized Patients
At present, 3 types of urine collection device can be distinguished: absorbent devices (diaper-type), penile clamps and penile collection sheaths.
- Trial name
- TUPELO (NCT07028996)
- Testing
- Daily use of the PEASY urine collection device for 5 days, Daily collection of patient feedback using a visual analog scale (0-100)
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Lower Urinary Tract Symptoms, Erectile Dysfunction
Impact of Treatment of Obstructive Sleep Apnea Syndrome by Continuous Positive Airway Pressure Equipment at Night on the Lower Urinary Tract Symptoms and the Erectile Dysfunction
To treat lower urinary tract symptoms (LUTS) and erectile dysfunction (ED), we mainly have symptomatic drug treatments. Some patients are resistant to the treatments that we have or are forced to stop treatments because of side…
- Conditions
- Lower Urinary Tract Symptoms, Erectile Dysfunction, Obstructive Sleep Apneas Syndrom
- Trial name
- NCT03547596
- Testing
- questionnaire passation
- Where
- France
- Volunteers
- 300 people
- Sponsor
- CHU de Reims
Stroke, Ischemic, Stroke Hemorrhagic
Urinary Disorders in Subacute Patients After Stroke
This observational study will address urinary disorders in subacute stroke patients. Patients without and with urinary disorders will be compared, and treatment outcome will be assessed among the latter.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Urinary Incontinence
- Trial name
- UIMK (NCT04078373)
- Testing
- Immediate urination, Bladder diary
- Where
- Slovenia
- Volunteers
- 250 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Pelvic Organ Prolapse
The Extended Operations And Pelvic Muscle Training In The Management Of Apical Support Loss Study
Women will be invited to participate in E-OPTIMAL at their last clinical follow-up visit for OPTIMAL (at 24 months post surgery).
- Trial name
- E-OPTIMAL (NCT01166373)
- Testing
- Enrollment video, SSLF, ULS
- Where
- 7 sites in United States
- Volunteers
- 285 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Urinary Incontinence
Stem Cells Treatment for the Local Urinary Incontinence After a Radical Prostate Cancer Surgery (HULPURO)
The purpose of this study is to evaluate the feasibility and security of the autologous e-ASC for the urinary incontinence after a radical prostate cancer surgery
- Trial name
- FLPURO (NCT01799694)
- Testing
- Inject of Autologous Adipose-derived stem cells
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Healthy
Pharmacologic Effects of Darifenacin and Tolterodine on Cardiovascular Parameters in Healthy Subjects
This study will evaluate the pharmacologic effects of exposure to darifenacin and tolterodine on cardiovascular parameters in healthy subjects 50 years of age and older
- Trial name
- NCT00413790
- Testing
- Darifenacin, Tolterodine
- Where
- 12 sites in United States
- Volunteers
- 162 people
- Sponsor
- Novartis