Clinical trials: Disruptive Behaviors
Attention Deficit Disorder With Hyperactivity
The Difference in the Mechanism of Action Between Two Brands of Dexamfetamine in Adults With ADHD
The goal of this clinical trial is to compare in the pk/pd profiles of magisterial dexamfetamine and Tentin in adults with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- DAVE (NCT05621174)
- Testing
- Dexamfetamine
- Where
- Netherlands
- Volunteers
- 1 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Onychophagia
Use of N-Acetylcysteine (NAC) in Fingernail Biting
To conduct a pilot randomized placebo-controlled feasibility trial of N-acetylcysteine (NAC) in onychophagia, preliminarily assessing the tolerability and effects of this pharmacotherapy on young adults who bite their…
- Trial name
- NCT01993849
- Testing
- N-Acetylcysteine (NAC)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Kevin Gray, MD
Attention Deficit Disorder With Hyperactivity
Effectiveness of Combined Medication Treatment for Aggression in Children With Attention Deficit With Hyperactivity Disorder (The SPICY Study)
This study will determine the advantages and disadvantages of adding one of two different types of drugs to stimulant treatment for reducing aggressive behavior in children with attention deficit with hyperactivity disorder…
- Trial name
- NCT00794625
- Testing
- Valproate, Risperidone, Stimulant medication
- Where
- 3 sites in United States
- Volunteers
- 270 people
- Sponsor
- Joseph Blader
Autism Spectrum Disorders, ADHD
Novel Measure of Social Deficits in Children
Autism Spectrum Disorders (ASD) feature impairments in social interaction and communication. Drug and behavioral treatments for ASD are undergoing rapid development, yet our diagnostic tools are not suitable for efficacy…
- Trial name
- OATS (NCT02035176)
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Attention Deficit Hyperactivity Disorder
Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) With Atomoxetine in Young Adults and Its Effects on Functional Outcomes
This study will evaluate atomoxetine's efficacy in treating attention-deficit/hyperactivity disorder (ADHD) symptoms and atomoxetine's effect on functional outcomes in young adults.
- Trial name
- NCT00510276
- Testing
- Atomoxetine hydrochloride
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 445 people
- Sponsor
- Eli Lilly and Company
ADHD
Effectiveness of a Digital Strategy-based Educational Skills Group for Secondary Students With Organization and Academic Motivation Challenges
The purpose of this study is to test the effectiveness of a telehealth-delivered skills training versus active control group for middle and high school students with ADHD symptoms.
- Trial name
- STAND-G (NCT05386251)
- Testing
- BPT/OST, Peer Support
- Sponsor
- Seattle Children's Hospital
Attention Deficit/Hyperactivity Disorder(ADHD), Alcohol Use
Smartphone-based Intervention for Young Adults With ADHD
The primary goal of this clinical trial is to test if a smartphone-based intervention is feasible \& acceptable among young adults with ADHD who also engage in risky drinking behaviors.
- Trial name
- NCT07654205
- Testing
- Ecological Momentary Assessment for ADHD and Substance Use - Intervention Group, Ecological Momentary Assessment for ADHD & Substance Use - Control Group
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Traci Kennedy
ADHD, Children
Omega-3 Fatty Acids, Neuroendocrine and Attention Deficit Hyperactivity Disorder (OMNeADHD)
This is a 12 week randomized controlled study on the effects of omega-3 fatty acids in youth with attention deficit hyperactivity disorder (ADHD) with omega-3 deficiency.
- Conditions
- ADHD, Children, Adolescents
- Trial name
- OMNeADHD (NCT07364331)
- Testing
- Omega-3
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- China Medical University Hospital
Healthy, CVA
Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019.
DELPhI software developed for the analysis of EEG recordings in response to magnetic stimulation in relation to clinical data.
- Conditions
- Healthy, CVA, Hemorrhage, TBI (Traumatic Brain Injury)
- Trial name
- NCT04095377
- Testing
- No intervention, this is a retrospective study.
- Where
- Israel
- Volunteers
- 875 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
Parkinson Disease
Trial Evaluating the Efficacy of Pimavanserin, a Selective Serotonin 5-HydroxyTryptamine-2A (5HT2A) Inverse Agonist, to Treat Impulse Control Disorders in Parkinson's Disease.
There is no consensus on the treatment of Impulse Control Disorder (ICD) in Parkinson Disease (PD) though it is recommended to reduce the dosage of dopamine agonists (DA).
- Trial name
- RETRO-PIMPARK (NCT06754553)
- Testing
- Assessment of severity of ICD (impulse control disorders), Assessment of motor and non-motors symptoms of PD Evaluation of hyper- and hypodopaminergic behaviors, Assessment of quality of life
- Where
- 16 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
ADHD
Structured Physical Training with and Without Cognitive Support for Adults with ADHD
Studies in children and adolescents with Attention-Deficit-Hyperactivity-Disorder (ADHD) have shown that physical exercise can improve the core symptoms of ADHD; inattention and hyperactivity.
- Trial name
- NCT05049239
- Testing
- Physical training, Physical training combined with cognitive support.
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Region Örebro County
Pathological Gambling
An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling
After completing all screening evaluations, subjects will receive unblinded N-Acetyl Cysteine 600 mg/day for 2 weeks. The dose will be raised to 1200 mg/day at visit 4 and to 1800 mg/day at visit 6 unless clinical improvement has…
- Trial name
- NCT00273702
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Attention Deficit Hyperactivity Disorder
Family Navigation to Improve ADHD Treatment Adherence for Minority Children
ADHD is the most common pediatric neurodevelopmental disorder and is associated with significant long-term impairments. Current guidelines recommend stimulant medication and/or behavioral therapy as first-line treatments for…
- Trial name
- I2-ART (NCT04591951)
- Testing
- I2-ART, Usual care
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
ADHD
Amphetamine Extended Release Tablets and Driving Performance in Subjects With Attention Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to assess the effect on driving performance of a single dose of amphetamine extended-release tablets (20 mg/tablet) compared with placebo at 45 minutes and 10 hours post-dose in young adults with ADHD.
- Trial name
- NCT04027361
- Testing
- Amphetamine Extended Release (ER) Tablet 20 mg
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Tris Pharma, Inc.
Attention-Deficit/Hyperactivity Disorder (ADHD)
Treating Young Children With Attention Deficit Hyperactivity Disorder
This project will evaluate the effectiveness of Methylphenidate versus Guanfacine in treating Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 3 through 5 years (inclusive), as measured by clinician rating of…
- Trial name
- TYCA (NCT07300956)
- Testing
- Guanfacine (GUA), Methylphenidate (MPH)
- Where
- 5 sites in United States
- Volunteers
- 370 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Attention Deficit Hyperactivity Disorder
ADZENYS XR-ODT™ in Children (4 to <6 Years) Diagnosed With Attention-deficit/Hyperactivity Disorder
This is a randomized, double-blind, flexible dose-titration, placebo-controlled, parallel-group study designed to evaluate the efficacy, safety, and tolerability of ADZENYS XR-ODT compared to placebo in children with ADHD.
- Trial name
- NCT07169162
- Testing
- ADZENYS XR-ODT
- Where
- United States
- Sponsor
- Aytu BioPharma, Inc.
ADHD
Testing "SupporT for ADHD and Related Treatment" (START) for Families of Children With ADHD
The randomized control trial (RCT) study includes 2 aims; one being to test whether START increases access to treatment for ADHD.
- Trial name
- START (NCT05796427)
- Testing
- SupporT for ADHD and Related Treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
ADHD, Attention Deficit Hyperactivity Disorder
Brain Plasticity Underlying Acquisition of New Organizational Skills in Children
Organizational, time management and planning (OTMP) skills deficits are impairing features of developmental disorders, such as Attention Deficit Hyperactive Disorder (ADHD), which compromise school performance and family…
- Conditions
- ADHD, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders
- Trial name
- NCT04108273
- Testing
- Organizational Skills Training
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- NYU Langone Health
Attention Deficit Hyperactivity Disorder
Effects of Attention Training on Children
Using a double-blind, randomized controlled design to investigate the therapeutic effects of interactive attention training for children with Attention Deficit Hyperactivity Disorder who are receiving conventional rehabilitation…
- Trial name
- NCT04375059
- Testing
- using interactive attention training system
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Gambling
Topiramate on Gambling-Related Behaviours
The quest for an effective medication therapy for problem gambling remains an important priority for the problem gambling treatment research field.
- Trial name
- NCT00370188
- Testing
- Topiramate
- Where
- Canada
- Sponsor
- Centre for Addiction and Mental Health