Clinical trials: Disruptive Behaviors
Hepatic Encephalopathy, Minimal Brain Dysfunction
Minimal Hepatic Encephalopathy in Hereditary Hemorrhagic Telangiectasian
HHT or Rendu-Osler-Weber disease is a genetic disease with an autosomal dominant inheritance pattern, characterized by widespread telangiectases that can involve several organs including the intestinal tract and the liver.
- Trial name
- mHE-HHT (NCT03586115)
- Testing
- Critical flicker frequency assessment
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Bari
Attention Deficit Disorder With Hyperactivity
Long-term Effects of Medication for ADHD
Single-centre open-label prospective study, enrolling 127 children and adolescents aged 6-17 years, who receive medication for ADHD of any subtype (presentation).
- Trial name
- LMA (NCT03250013)
- Testing
- ADHD medications
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Göteborg University
Autism Spectrum Disorder, Irritability
Behavior Therapy for Irritability in Autism
This is a clinical trial of a novel intervention, Behavioral Therapy for Irritability and Aggression (BTIA), for adolescents on the autism spectrum.
- Conditions
- Autism Spectrum Disorder, Irritability, Disruptive Behavior, Anger
- Trial name
- BTIA (NCT04654260)
- Testing
- Behavioral Therapy for Irritability in Autism, Psychoeducation and Supportive Therapy (PST)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Yale University
Trichotillomania
Trichotillomania: Group Cognitive-Behavioral Therapy
Objective: Trichotillomania is a psychiatric condition characterized by chronic pulling and plucking of one's own hair. Cognitive behavioral therapy shows promise as a treatment.
- Trial name
- NCT01968343
- Testing
- Cognitive-behavioral therapy., Supportive therapy.
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Attention Deficit/Hyperactivity Disorder
A Safety/Tolerability and PK Study With Azstarys® in Children With ADHD
The is a multicenter, dose-optimized, open-label, safety/ tolerability and pharmacokinetic (PK) study with Azstarys® in children 4 and 5 years of age with attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- KP415P02 (NCT05721235)
- Testing
- Serdexmethylphenidate (SDX) and dexmethylphenidate (d-MPH)
- Where
- 20 sites in United States
- Volunteers
- 123 people
- Sponsor
- Corium, Inc.
Attention Deficit Hyperactivity Disorder
Behavioral Intervention for Children With Attention Deficit Hyperactivity Disorder(ADHD)
ADHD children have executive function (EF) impairments,so we randomize the children to the training or a waitlist to improve EF ,adding contingent reinforcement to ascertain whether EF deficits are amenable to the training in…
- Trial name
- NCT02327585
- Testing
- A randomized controlled study of Executive Function training for children with ADHD
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Min Chen
Tourette Syndrome, Tourette's Disorder
Assessment of Children With Tic Onset in the Past 6 Months
The purpose of this research is to study why most children who have tics never develop Tourette syndrome but some do. In other words, we aim to find features that may predict whose tics will go away and whose tics will continue…
- Conditions
- Tourette Syndrome, Tourette's Disorder, Chronic Motor or Vocal Tic Disorder, Transient Tic Disorder
- Trial name
- NewTics (NCT01177774)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Washington University School of Medicine
ADHD
Efficacy Study of Polyunsaturated Fatty Acids in Children and Adolescents With Attention Deficit/ Hyperactivity Disorder
This study will determine the nutritional efficacy of Polyunsaturated Fatty Acids (PUFAs) in combination with zinc and magnesium, in children and adolescents diagnosed with Attention Deficit/ Hyperactivity Disorder (ADHD).
- Trial name
- PAD (NCT01340690)
- Testing
- ω-3 fatty acids suspension
- Where
- 5 sites in Germany
- Volunteers
- 284 people
- Sponsor
- Johannes Gutenberg University Mainz
Trichotillomania
Feasibility Study for Treating Trichotillomania With Wearable Device and App System
Trichotillomania is characterized by recurrent hair pulling resulting in hair loss causing significant distress and impairment which persists despite repeated attempts to stop.
- Trial name
- NCT04241120
- Testing
- Device and app system designed for participant to self-administer Habit Reversal Training, Reminder bracelet control condition
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HabitAware Inc.
Gambling Disorder
COMpulsive Gambling: Efficacy of DEEP Transcranial Magnetic Stimulation With H7 COIL
This study aims to investigate whether a treatment called high-frequency repetitive transcranial magnetic stimulation (rTMS) can help reduce the symptoms of gambling disorder and whether it is safe and well tolerated.
- Trial name
- COMET-7 (NCT07828782)
- Testing
- active r-TMS
- Volunteers
- 60 people
- Sponsor
- Sveti Ivan Psychiatric Hospital
COVID-19, Chronic Heart Failure
Intermittent Hypoxic-hyperoxic Training in Patients With Cardiovascular Pathology After COVID-19 Infection.
Aim of this prospective, interventional, single-center, randomized study is to evaluate the efficacy and safety of intermittent hypoxic-hyperoxic training (IHHT) as a rehabilitation method in patients with cardiovascular…
- Conditions
- COVID-19, Chronic Heart Failure, Hypertension, Arrhythmia
- Trial name
- NCT05379608
- Testing
- Intermittent hypoxic-hyperoxic training, Intermittent hypoxic-hyperoxic training/control
- Where
- Russia
- Volunteers
- 43 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Attention Deficit Hyperactivity Disorder
New Technologies to Help Manage ADHD
Cluster randomized controlled trial to evaluate the general effectiveness of intervention compared to control on medication continuity as measured by prescriptions written and other more proximal outcomes during the first six…
- Trial name
- NCT02390791
- Testing
- enhanced myADHDportal.com, treatment as usual standard portal
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Attention Deficit Disorder With Hyperactivity
Reducing Attention Deficit Hyperactivity Disorder in Kindergarten and Pre-Kindergarten Children
This study will determine the effectiveness of an intervention for preventing at-risk kindergarten and pre-kindergarten children from developing attention deficit hyperactivity disorder.
- Trial name
- NCT00895908
- Testing
- Friendship Group, Academic tutoring
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Penn State University
Pathological Gambler
Effect of rTMS in Pathological Gamblers
The gambling problem is characterized by a loss of control and an excessive focus on the gambling practice. Currently, the treatment of pathological gamblers is often complex and multidimensional, it notably includes…
- Trial name
- NCT02552524
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
ADHD
Improving Medication Adherence in ADHD Adolescents
Investigates whether a family-based intervention for adolescents with Attention Deficit Hyperactivity Disorder (ADHD) will improve adherence to prescribed medication regimen in adolescents with history of medication nonadherence.
- Trial name
- NCT02271880
- Testing
- Medication as usual, STAR
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Florida International University
Attention-Deficit/Hyperactivity Disorder
The Safety and Efficacy of SPD465 in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
This is a phase 2, randomized, multi-center, double-blind, 3-period and 3-treatment crossover study designed to evaluate the safety and duration of efficacy of SPD465 (50 or 75 mg) compared with placebo and an immediate release…
- Trial name
- NCT00928148
- Testing
- SPD465, Immediate Release Amphetamine Salt
- Volunteers
- 86 people
- Sponsor
- Shire
Stroke, Relatives
Can Stroke Patients and Their Caregiver Benefit From Additive Mindfulness Training
The main purpose of the study is to find out if MBSR (Mindfulness) in addition to occupational therapy, can improve the therapeutic results in stroke-patients and help relatives of stroke patients to improve their quality of life.
- Conditions
- Stroke, Relatives, Motor Disorder, Attention Deficit
- Trial name
- NCT03271788
- Testing
- Mindfulness, MBSR
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
ADHD, Trichotillomania
Methylphenidate in ADHD With Trichotillomania
This study will evaluate the safety and effectiveness of methylphenidate in treating attention deficit hyperactivity disorder (ADHD) in children with both ADHD and trichotillomania.
- Trial name
- NCT00552266
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Geha Mental Health Center
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Impact of Combined Medication and Behavioral Treatment for ASD & ADHD
Children with comorbid autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) have significantly worse outcomes than those with either ASD alone or ADHD alone.
- Trial name
- NCT03242772
- Testing
- Amphetamine, ESDM informed parent coaching
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Duke University
Attention-deficit/Hyperactivity Disorder
Attention-deficit/Hyperactivity Disorder Translational Center for Identifying Biomarkers
The purpose of this study was to identify genetic, brain morphologic, and environmental biomarkers that contribute to the pathophysiology of attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT02623114
- Testing
- methylphenidate, atomoxetine
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Seoul National University Childrens Hospital