Clinical trials: Distal Femoral
Periprosthetic Fractures, Distal Femur Fractures
Periprosthetic Distal Femur Fracture
A periprosthetic distal femur fracture is a fracture close to a knee implant. This type of fracture is often difficult to fix because of the close proximity of the two surgical implants which can sometimes interfere with proper…
- Trial name
- NCT01973712
- Testing
- Locked Compression Plating, Retrograde Intramedullary Nailing (RIMN)
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- Unity Health Toronto
Periprosthetic Fracture Around Prosthetic Joint Implant
Weight-Bearing CT and Conventional Periprosthetic Distal Knee Fractures
Total knee arthroplasty (TKA) is a surgical procedure commonly conducted for patients with end-stage knee osteoarthritis, often leading to improved pain relief and function.
- Trial name
- NCT06909916
- Testing
- Periprosthetic Fracture Knee Repaired CT Scans
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Tibial Fractures, Femoral Fractures
Distal Locking Using an Electromagnetic Field Guided Computer Based Real Time System for Orthopaedic Trauma Patients
Hypothesis: Utilization of the "wand" method will enhance improvements in drill placement, locking nail placement during tibia and femur fracture repairs, and offer less radiation exposure and less operative time.
- Trial name
- Sure Shot (NCT01183078)
- Testing
- free-hand, Wand technique
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Wake Forest University Health Sciences
Prosthesis Failure
Medium-term Results of the LPS™ System for Segmental Resection of the Distal Femur, a Multicenter Retrospective Study (RESIF)
The reconstruction of the distal femur using modular systems has become increasingly popular over the years, surpassing primary arthrodesis or amputation.
- Trial name
- RESIF (NCT06928948)
- Testing
- Femur replacement
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Brest
Periprosthetic Bone Loss in Total Knee Replacement
Use Quantitative Microradiography to Predict the Periprosthetic Bone Loss in Distal Femur After Total Knee Arthroplasty
The investigators hypothesized that the microarchitecture of bone influence the degree of periprosthetic bone loss after total knee arthroplasty surgery.
- Trial name
- NCT01618149
- Testing
- dual energy x-ray absorptiometry
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Distal Femur Fracture
Mobile Weight-Support Therapy (MWeST) for Mobility After Geriatric Fracture
This is a two-year study proposal to assess feasibility of MWeST (Mobile Weight-Support Therapy) implementation after geriatric fracture and its effects on functional and patient-reported outcomes.
- Trial name
- MWeST (NCT03864367)
- Testing
- Device - Prism Medical FGA-700 Bariatric Floor Lift
- Where
- United States
- Sponsor
- Washington University School of Medicine
Distal Femoral Musculoskeletal Tumors
Functional Outcomes and Quality of Life in Musculoskeletal Tumor Patients With Distal Femoral Megaprostheses
This study aims to evaluate the functional outcomes of patients with distal femur tumor prostheses in comparison to a matched control group.
- Trial name
- FOQ-DFP (NCT06282198)
- Where
- Spain
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Femoral Fractures
A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures
This study looks at two (2) types of surgical treatments and hopes to answer the question, "which is the best way to surgically treat a distal femur fracture?" Both procedures being studied are standard of care (used routinely)…
- Trial name
- NCT00429663
- Testing
- reamed, interlocking intramedullary nail, locking periarticular plate
- Where
- 22 sites in United States
- Volunteers
- 160 people
- Sponsor
- Boston Medical Center
Osteosarcoma
Efficacy of Exercise Program on Osteosarcoma Patients
This study will be conducted to investigate the effect of selected therapeutic exercises compared to standard exercise program in improving ROM, muscle strength and functional outcomes in distal femur osteosarcoma patients who…
- Trial name
- NCT04757064
- Testing
- standard rehabilitation protocol
- Volunteers
- 40 people
- Sponsor
- Cairo University
Femoral Fractures
Supracondylar Distal Femur Fractures and Abaloparatide
Supracondylar femur fractures in the geriatric population present a unique challenge to the orthopaedic surgeon both in terms of fixation, healing, and final extremity axial alignment.
- Trial name
- NCT04626141
- Testing
- Abaloparatide
- Where
- United States
- Sponsor
- Daniel Horwitz
Osteo Arthritis of the Knee
Comparison of Distal IPACK and Popliteal Plexus Block Combined With Femoral Triangle Block After Total Knee Arthroplasty
This study aims to investigate the effect of femoral triangle block combined with popliteal plexus block and distal IPACK block on postoperative pain after total knee arthroplasty (TKA)
- Trial name
- NCT07130552
- Testing
- femoral triangle block and popliteal plexus block, Femoral triangle block and distal iPACK
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Karaman Training and Research Hospital
Fracture Non Union, Fracture Healing
Prospective Validation Study of the CD8+TEMRA Cells As a Prognostic Biomarker of Healing Outcome After Fracture
In approx. 10-15% of all fracture patients, there is a prolonged healing time or even a complete absence of fracture healing (non-union).
- Conditions
- Fracture Non Union, Fracture Healing, Long Bone Delayed-Union Fracture, Humerus Shaft Fracture
- Trial name
- BioBone (NCT06658379)
- Testing
- CD8+TEMRA
- Where
- 7 sites in Germany
- Volunteers
- 640 people
- Sponsor
- Charite University, Berlin, Germany
Distal Femur Fractures
Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated With Locked Plate Fixation
The purpose of this study is to evaluate the performance of Dynamic Locking Screws (DLS) used to stabilize the shaft component of distal femur fractures in comparison to standard locking screws (SLS).
- Trial name
- NCT01693367
- Testing
- DLS 5.0 (Dynamic locking screws), SLS (Standard locking screw)
- Where
- 12 sites in United States, Austria and 2 more
- Volunteers
- 5 people
- Sponsor
- AO Innovation Translation Center
Hip Fractures, Tibial Fractures
Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
Prospective data will be collected in approximately 3500 patients (700 per 5 injury groups). Patients will be followed up according to the standard (routine) for up to 1 year after the treatment.
- Conditions
- Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal
- Trial name
- NCT04113044
- Testing
- All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 1,500 people
- Sponsor
- AO Innovation Translation Center
Proximal (Subtrochanteric)Femoral Fractures, Distal Femoral Fractures
Evaluation of the Safety and Efficacy of a Guided Bone Regeneration Membrane for the Treatment of Femoral Fractures
Certain types of fractures require surgical intervention that may involve the use of bone grafts or bone graft substitutes. Many of the materials used as bone graft substitutes suffer from disadvantages such as soft tissue…
- Trial name
- NCT01687530
- Testing
- AMCA Bone Membrane.
- Where
- 2 sites in Israel
- Volunteers
- 48 people
- Sponsor
- RegeneCure, Ltd.
Femur Fracture
Dual Implant Versus Single Implant Distal End of Femur
This research study is being conducted to examine the effect of two versus one fixation device for fixation of distal femur fractures.
- Trial name
- NCT06032299
- Testing
- Single Distal Femur Implant, Dual Distal Femur Implant
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Femur Fracture
RFN-Advanced Retrograde Femoral Nailing System
This study is a retrospective chart review of the safety and performance Standard of Care data on individuals that have previously been implanted with the femur nail of the RFNA System for the internal fixation of the femur.
- Trial name
- RFNA (NCT05668117)
- Testing
- Depuy Synthes Advanced Retrograde femoral nail
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Alabama at Birmingham
Distal Femur Fractures
Radiostereometric Analysis of Fracture Healing in Distal Femur Fractures
The investigators are doing this research study to look at how distal femoral fractures (knee bone break) heal. In this study, the investigators will use Radiostereometric Analysis (RSA) to look at how the pieces of femur bone…
- Trial name
- RSA (NCT01593176)
- Testing
- Placement of RSA beads
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Humeral Neck Fracture, Vertebral Fracture
Integrated Rehabilitation Program for Fractures
The recovery of range of motion and muscle power after surgical intervention of the fracture will mostly affect patient's daily activities. So postoperative rehabilitation program will play the important role.
- Conditions
- Humeral Neck Fracture, Vertebral Fracture, Distal Radial Fracture, Hip Fractures
- Trial name
- NCT01817933
- Testing
- physical therapy
- Sponsor
- Changhua Christian Hospital
Femur Fracture, Tibial Fractures
Distal Targeter vs Free-hand
This study is a randomized controlled trial comparing the use of two different surgical techniques--free-hand versus distal targeting jig-based for distal interlock screw--placement and their effects on total operative time and…
- Conditions
- Femur Fracture, Tibial Fractures, Nonunion of Fracture, Nonunion of Fracture of Tibia
- Trial name
- NCT05613257
- Testing
- Distal targeting jig, Free-hand/perfect circles technique
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Cedars-Sinai Medical Center