Clinical trials: Distal Pancreatectomy
Digital Health
Remote Clinical Monitoring After Robotic Distal Pancreatectomy
This feasibility trial has three main objectives: To investigate the impact of the transmural care pathway TOTeM on the Length of Stay (LOS) for patients undergoing robotic distal pancreatectomy.
- Trial name
- TOTEM (NCT06881602)
- Testing
- Remote clinical monitoring
- Volunteers
- 20 people
- Sponsor
- Jessa Hospital
Minimally Invasive Distal Pancreatectomy
Registrar Performances in MIDP
This study aimed to determine whether registrar involvement in minimally invasive distal pancreatectomy (MIDP) was associated with adverse outcomes.
- Trial name
- NCT04429074
- Testing
- Minimally invasive distal pancreatectomy
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Montpellier
Pancreatic Neoplasms
Reinforced Staple Line on Leak Rate in Distal Pancreatectomy
The investigators propose a randomized, controlled trial of stapled pancreatic transection versus mesh reinforced stapled pancreatic transection.
- Trial name
- NCT01359410
- Testing
- Mesh reinforced staple line (SEAMGUARD), Stapled without mesh reinforcement (PER-STRIPS DRY)
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Washington University School of Medicine
Distal Pancreatectomy
TissueLink Versus SEAMGUARD After Distal Pancreatectomy
The purpose of this research study is to find a lowest leak rate following a distal pancreatectomy (removal of the left side of the pancreas).
- Trial name
- PLATS (NCT01051856)
- Testing
- SEAMGUARD with bioabsorbable staple, TissueLink with radiofrequency ablation
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- Mayo Clinic
Pancreatic Neoplasms, Surgical Procedure, Unspecified
Multivisceral Resection in Distal Pancreatectomy
The objective of the study is to evaluate the characteristics of the patients and the results of morbidity and mortality after distal pancreatectomy isolated or accompanied by multivisceral resection including cholecystectomy.
- Trial name
- ERPANDIS-MRV (NCT04317352)
- Testing
- MVR
- Where
- Spain
- Volunteers
- 435 people
- Sponsor
- Universidad de Extremadura
Cyst of Pancreas, Pancreatectomy
Is Intraperitoneal Drainage Necessary Following Distal Pancreatectomy?
The goal of this clinical trial is to analyze if intraperitoneal drainage is necessary following distal pancreatectomy. This study aims to determine whether the omission of routine intraperitoneal drainage in the setting of…
- Conditions
- Cyst of Pancreas, Pancreatectomy, Pancreas Neoplasm
- Trial name
- NCT05720338
- Testing
- 19 French Blake Drain
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Case Comprehensive Cancer Center
Pancreatic Fistula, Distal Pancreatectomy
Comparison Between Two Methods of Pancreatic Transection in Distal Pancreatectomy
Several systematic reviews have investigated the management of the pancreatic stump in order to reduce the postoperative pancreatic fistula (POPF) rate after distal pancreatectomy (DP).
- Trial name
- TRUDY (NCT03880773)
- Testing
- Stapler, ultrasonic shears
- Where
- Italy
- Volunteers
- 152 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Pancreatoduodenectomy, Periampullary Carcinoma
Application of "Heidelberg Triangle" Dissection in Pancreatoduodenectomy and Distal Pancreatectomy
Aim of the study : To evaluate the effect and safety of "Heidelberg Triangle" dissection (TRIANGLE operation) combined with Pancreatoduodenectomy or Distal Pancreatectomy on the prognosis of pancreatic cancer and periampullary…
- Conditions
- Pancreatoduodenectomy, Periampullary Carcinoma, Pancreatic Cancer
- Trial name
- NCT05703581
- Testing
- TRIANGLE operation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Pancreatic Tumor
Robotic vs. Laparoscopic Distal Pancreatectomy for Pancreatic Cancer
The present randomized controlled trial evaluates the incidence of R1 resections in patients undergoing robotic distal pancreatectomy compared to the laparoscopic technique.
- Trial name
- DAVID (NCT02269683)
- Testing
- Robot-assisted distal pancreatectomy, Laparoscopic distal pancreatectomy
- Where
- Germany
- Sponsor
- Technische Universität Dresden
Distal Pancreatectomy
Textbook Outcome in Distal Pancreatectomy
The auditing of results and improving the quality of care are key aspects of surgical activity. Patients, hospitals and health institutions need information on the results obtained with specific procedures.
- Trial name
- TO-ERPANDIS (NCT05423288)
- Testing
- Distal pancreatectomy (DP)
- Volunteers
- 450 people
- Sponsor
- Universidad de Extremadura
Pancreas; Fistula
Radiofrequency-assisted Transection of the Pancreas vs Stapler
Main objective: The main end-point of this study is to compare in a randomized clinical trial that radiofrequency-assisted pancreas transection (RF) reduces the incidence of postoperative pancreatic fistula (POPF) compared to the…
- Trial name
- TRANSPAIRE (NCT04402346)
- Testing
- Radiofrequency-assisted pancreas transection, Stapler assisted pancreas transection
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- Patricia Sanchez Velazquez
Tumor of Exocrine Pancreas
Distal Pancreatectomy With Partial Splenectomy for Pancreatic Tumors
Most resectable tumors arising in the body or tail of the pancreas are malignancies or premalignancies which are surgically treated with distal pancreatectomy in combination with splenectomy.
- Trial name
- NCT01412684
- Testing
- Distal pancreatectomy with partial splenectomy
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Whipple Procedure, Distal Pancreatectomy
Music Therapy in Patients Undergoing Pancreatic Surgery (MUSIC PUPS)
Pilot single arm non-randomized trial to determine the feasibility and acceptability of: 1) a tailored music-assisted relaxation and imagery intervention; 2) biological sample collection; and 3) mobile device patient-reported…
- Conditions
- Whipple Procedure, Distal Pancreatectomy, Acute Pain
- Trial name
- MUSIC PUPS (NCT06123013)
- Testing
- Music Assisted Relation Intervention (MARI)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University Hospitals Cleveland Medical Center
Post Operative Pancreatic Fistula
Does Reinforcement of the Staple Line in Left Pancreatectomy Reduce the Rate of Pancreatic Fistula?
Dividing pancreas when performing left-sided resections opens the risk for leakage from the divided end of the pancreas. Pancreatic juices could have a severe effect on surrounding abdominal tissues with abscess formation…
- Trial name
- NCT02149446
- Testing
- Surgisis (C-SLRA-ECH60) made by COOK Medical
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska University Hospital
Pancreatectomy, Fluid Therapy
Comparison of Fluid Requirements in Pancreatectomy: Laparotomy vs. Laparoscopy
In this retrospective cohort study, the investigators reviewed and analyzed the electronic medical records of consecutive patients who underwent distal pancreatectomy either via laparotomy or laparoscopy.
- Conditions
- Pancreatectomy, Fluid Therapy, Laparoscopy
- Trial name
- NCT03060408
- Volunteers
- 304 people
- Sponsor
- Seoul National University Bundang Hospital
Pancreatic Fistula, Pancreatic Neoplasms
Treatment of the Pancreatic Stump With Neoprene®-Based Glue After High-risk Pancreatoduodenectomy
The study evaluates the safety and efficacy of Neoprene-based glue in the management of pancreatic stump after pancreatoduodenectomy (PD) in patients at high risk for pancreatic fistula and early neoplastic recurrence, compared…
- Conditions
- Pancreatic Fistula, Pancreatic Neoplasms, Postoperative Complications
- Trial name
- NCT03738787
- Testing
- Pancreatic duct occlusion with Neoprene, Pancreato-Jejunal anastomosis
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Pancreatic Cancer
Left Celiac Plexus Resection for Pancreatic Cancer at the Body and Tail
This is a prospective study of left celiac plexus resection for pancreatic cancer at the body and tail during standard distal pancreatectomy.
- Trial name
- NCT02117895
- Testing
- Celiac plexus resection, Pancreatectomy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Fudan University
Pancreaticoduodenectomy, Distal Pancreatectomy
The Novel Modified Cattell-Warren Duct-To-Mucosa Pancreaticojejunostomy Technique Significantly Reduces POPF.
Pancreatic surgeries, such as pancreaticoduodenectomy and distal pancreatectomy, are associated with high morbidity and mortality. The most common cause of this morbidity is postoperative pancreatic fistula(POPF).
- Conditions
- Pancreaticoduodenectomy, Distal Pancreatectomy, Postoperative Pancreatic Fistula
- Trial name
- POPF (NCT07038161)
- Testing
- Modified Cattell-Warren duct-to-mucosa pancreaticojejunostomy, Institutional Prehabilitation Protocol
- Where
- Nepal
- Volunteers
- 27 people
- Sponsor
- Nepal Medical College and Teaching Hospital
Pancreatic Fistula
A Prospective Randomized Trial of Efficacy of Stump Closure for Distal Pancreatectomy
Overall morbidity rate remained high after distal pancreatectomy (DP), ranging from 30% to 60%. Whilst postoperative pancreatic fistula (POPF) remains serious and also is one of the most common complications after DP (12% to…
- Trial name
- NCT03201653
- Testing
- Stump closure using NU-KNIT SURGICEL
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- National Taiwan University Hospital
Pancreatic Carcinoma
Endoscopic Botulinum Toxin Injection in the Prevention of Postoperative Pancreatic Fistula Following Distal Pancreatectomy
This phase II trial studies the effect of botulinum toxin (Botox) in preventing postoperative pancreatic fistula after distal pancreatectomy.
- Trial name
- NCT04965311
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- OHSU Knight Cancer Institute