Clinical trials: Distension
Pregnancy, Prolonged, Pre Eclampsia
Foley Catheter Versus Vaginal Misoprostol for Cervical Ripening and Induction of Labor
PURPOSE: The purpose of this study is to determine the effectiveness of balloon dilatation (Foley) with vaginal misoprostol for cervical ripening and induction of labor.
- Conditions
- Pregnancy, Prolonged, Pre Eclampsia, Oligohydramnios
- Trial name
- NCT01140971
- Testing
- Misoprostol, Foley
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Municipal Hospital Vila Nova Cachoeirinha
Surgery
Methods of Establishing Intersegmental Plane in Segmentectomy
The aim of this study is to perform a prospective, single-center, randomized controlled study to explore whether closed insufflation technique is not inferior to dilatation and collapse technique in segmentectomy, and to provide…
- Trial name
- NCT06015399
- Testing
- Implementation of closed insufflation technique during segmentectomy, Implementation of dilatation and collapse technique during segmentectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Xiangya Hospital of Central South University
Marfan Syndrome
Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome
The purpose of this study is to evaluate the efficacy of Losartan versus Atenolol in the progression of aortic dilatation in patients with Marfan syndrome.
- Trial name
- LO-AT-MARFAN01 (NCT01145612)
- Testing
- Losartan, Atenolol
- Where
- 2 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Forteza, Albert, M.D.
Percutaneous Coronary Intervention (PCI), Acute Myocardial Infarction
Aerobic Exercise-induced Effect on Endothelial Function in Patients With Ischaemic Heart Disease
Endothelial dysfunction is one of the aetiological factors in ischaemic heart disease (IHD). Aerobic exercise is effective in improving endothelial function, as measured by flow-mediated dilation (FMD), in patients with IHD.
- Conditions
- Percutaneous Coronary Intervention (PCI), Acute Myocardial Infarction, Angina (Stable), Unstable Angina Pectoris
- Trial name
- ENDO-R (NCT06788275)
- Testing
- Aerobic exercise (MIT), Aerobic exercise (Short HIIT), Aerobic exercise (Long HIIT)
- Where
- 2 sites in Spain
- Volunteers
- 132 people
- Sponsor
- Instituto de Investigación Sanitaria y Biomédica de Alicante
Healthy Conditions
Role of Endothelin-1 in Flow-mediated Dilatation
Endothelial dysfunction of conduit arteries contributes to the increased morbidity and cardiovascular mortality in patients with essential hypertension and appears increasingly as an independent therapeutic target.
- Trial name
- Endothelin (NCT02086253)
- Testing
- BQ-788 and/or BQ-123
- Where
- France
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Vestibular Schwannoma
Secondary Endolymphatic Hydrops and Vestibular Schwannomas on 3 Tesla MRI
Endolymphatic hydrops is well known of the lay public in its primary form that is Ménière disease. Nowadays, the best w ay to approach it in vivo, is to use magnetic resonance imaging (MRI).
- Trial name
- NCT03593577
- Where
- France
- Volunteers
- 185 people
- Sponsor
- University Hospital, Strasbourg, France
Legally Induced Abortion Without Mention of Complication
Mifepristone Versus Osmotic Dilators in Conjunction With Misoprostol for Cervical Preparation Prior to D&E at 14-19 Weeks
Dilation and evacuation (D\&E) is a common surgical procedure in the U.S. Adequate pre-operative preparation of the uterine cervix is an important part of preventing complications of the procedure.
- Trial name
- NCT02679092
- Testing
- Misoprostol, Mifepristone, Hygroscopic cervical dilators
- Where
- United States
- Sponsor
- Stanford University
Adhesive Capsulitis of the Shoulder
Capsular Distension Versus Corticosteroid Injection in Adhesive Capsulitis
Adhesive capsulitis is a common and disabling shoulder condition characterized by pain and progressive limitation of range of motion.
- Trial name
- NCT07409779
- Testing
- capsular distension, Betamethasone (Diprostene®) Injection
- Where
- Tunisia
- Volunteers
- 50 people
- Sponsor
- Faculty of Medicine of Tunis
Pain
Stimulation and Validation of the Pupillary Dilation for the Detection of Pain in Analgosedated Patients Under Mechanically Ventilation in Intensive Care Unit
This project has 2 phases. Phase 1: diagnostic test study, to evaluate the efficacy of the variation of pupillary size (PDR) to detect pain in ICU patients regarding to Behavioural Pain Scale (BPS) and ESCID (Conductual Scale…
- Trial name
- NCT04078113
- Testing
- Pupillometer
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Basque Health Service
Esophageal Disruption, Esophageal Obstruction
Evaluation of the Effectiveness of Endoscopic "Rendez-vous" Technique Foresophageal Reconstructions for the Treatment of a Total and Extensive Disruption of the Esophagus
Complete esophageal obstructions leads to definitive fasting. The rendez-vous endoscopic approach had already been described for complex stenoses but never for disruption with loss of tissue and SES.
- Trial name
- NCT02166957
- Testing
- Recanalization
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Société Française d'Endoscopie Digestive
Aortic Valve Stenosis
Post-Dilatation in Balloon-Expandable TAVI Prostheses
Asymmetrical and inadequate expansion of transcatheter heart valves (THVs) have been described as a key predictor of impaired valve hemodynamic performance predisposing patients for bioprosthetic valve dysfunction (BVD) and…
- Trial name
- DUOTAP (NCT07477002)
- Testing
- Post-dilatation
- Where
- Austria
- Volunteers
- 146 people
- Sponsor
- Medical University of Vienna
Uterine Bleeding
Comparison Between D&C and Hysteroscopy in Management of AUB in Perimenopausal Women
The aim of this study is to compare dilatation and curettage with hysteroscopy in obtaining an accurate diagnosis of the etiology of abnormal uterine bleeding and outlining a mode of treatment-specific to the cause.
- Trial name
- NCT02705222
- Testing
- D&C, Hysteroscopy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mohamed Sayed Abdelhafez
Coronary Artery Disease
Sauna Bathing to Improve Vascular Health of Adults With Heart Disease
This study is a clinical trial that will determine if sauna bathing improves blood vessel health in adults aged 50-70 years with heart disease.
- Trial name
- NCT03620539
- Testing
- Lifestyle intervention
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- Montreal Heart Institute
Healthy
Effect of Immersion, Performed Under the Conditions of Obstetrical Dilatation Bath, on Diuresis and Hemodynamic Variables in Young Women
Like in the full immersion, studied in the context of diving, immersion in water causes a cascade of events with hemodynamic and hormonal consequences.
- Trial name
- IMMERSION (NCT02409953)
- Testing
- Lying in a bath during 2 hours, Lying in a bed during 2 hours
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Tracheostomy Complication, Inflammation
Postoperative Inflammation and Recovery After Tracheostomy
The main purpose of this study is to examine if there are differences in postoperative inflammation following percutaneous dilatation tracheostomy versus surgical tracheostomy in intensive care unit patients.
- Conditions
- Tracheostomy Complication, Inflammation, Post-operative Complications
- Trial name
- NCT02096640
- Testing
- Type of surgical teqnique for tracheostomy
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Sormland County Council, Sweden
Nonulcer Dyspepsia
An Exploratory Study Examining The Effects Of Taking GW679769 Once-Daily For 4 Days In Patients With Functional Dyspepsia
This study was designed is to examine the idea that GW679769 has an effect on three of the pathophysiological disturbances reported in patients with Functional Dyspepsia (FD): impaired stomach accommodation to a meal, delayed…
- Trial name
- NCT00358410
- Testing
- GW679769 oral tablets
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- GlaxoSmithKline
Aortic Valve Stenosis and/or Insufficiency, Hypoattenuated Leaflet Thickening
SYMmetric Valve fraME Expansion To Reduce hYpoattenuated Leaflet Thickening After Balloon-expandable TAVI: the SYMMETRY Trial
Rationale: Transcatheter aortic valve implantation (TAVI) has become the standard of care for aortic stenosis across all surgical risk categories, including low-risk, younger patients (≥70 years).
- Conditions
- Aortic Valve Stenosis and/or Insufficiency, Hypoattenuated Leaflet Thickening, Valve Expansion, Transcatheter Aortic Valve Replacement
- Trial name
- SYMMETRY (NCT07872020)
- Testing
- Double-TAP post-dilatation
- Where
- 5 sites in Germany, Netherlands
- Volunteers
- 422 people
- Sponsor
- Erasmus Medical Center
Artery Disease
Investigating the Safety and Clinical Performance of Eight iVascular Devices for Endovascular Intervention in Renal, Iliac or Femoral Arteries
The rationale of this study is to confirm and support the clinical safety and performance of any of these products in a real-world population of 209 patients who underwent an endovascular intervention within standard-of-care of…
- Trial name
- NCT05902923
- Testing
- endovascular intervention
- Where
- 6 sites in France
- Volunteers
- 209 people
- Sponsor
- iVascular S.L.U.
Coronary Artery Disease, Heart Disease, Ischemic
Artimes Pro Low Profile Dilatation Catheters for Pre-Dilatation in Patients With Symptomatic Ischemic Heart Disease
This is a prospective, non-randomized, open label, multi-center study including 60 patients with symptomatic ischemic heart disease with 70%-100% coronary artery stenoses and occlusions enrolled and treated in this…
- Conditions
- Coronary Artery Disease, Heart Disease, Ischemic, Coronary Stenosis
- Trial name
- NCT03301246
- Testing
- Artimes Pro Low Profile Dilatation Catheter
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Eminence Clinical Research, Inc.
Leukemia
Ultrafiltration (Aquapheresis) in Patients With Leukemia and Severe Fluid Overload
The goal of this clinical research study is to learn about the safety and level of effectiveness of aquapheresis compared to diuretic drugs. Diuretic drugs are designed to help the kidneys to form more urine.
- Trial name
- NCT01508260
- Testing
- Aquapheresis, Furosemide
- Sponsor
- M.D. Anderson Cancer Center