Clinical trials: Distension
Bleeding;Post D&C, PAIN, ANXIETY, AND COMFORT
THE EFFECT OF VIRTUAL REALITY APPLICATION ON PAIN, ANXIETY, AND COMFORT DURING CURETTAGE/DILATATION
The problems experienced by women at the stage of deciding to have a miscarriage, during and after miscarriage differ and their anxiety levels vary.
- Trial name
- NCT06403579
- Testing
- virtula reality goggles
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Inflammation Process, Endothelial Dysfunction
Ultrasound Markers of Systemic Inflammation
The aim of this study was to measure whether the flow rate through the brachial artery and inflammatory markers were associated with the development of tissue edema in the surgical intensive care unit patients.
- Conditions
- Inflammation Process, Endothelial Dysfunction, Vasomotor Arterial Disorder, Vascular Dilation
- Trial name
- NCT05798182
- Testing
- Ultrasound measurement
- Where
- Croatia
- Volunteers
- 61 people
- Sponsor
- Osijek University Hospital
Pain
Electrical Stimulation Over Acupuncture Points in Reduction of Rectal Discomfort Distension
Colonoscopy is a stressful and unpleasant procedure especially during the passage of the endoscope through angulations of colon. Electro-acupuncture is one of the alternative to reduce colorectal discomfort.
- Trial name
- NCT01551654
- Testing
- Transcutaneous Electrical Nerve Stimulation (ITO Company )
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Heart Failure, Reduced Ejection Fraction
Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.
The purpose of this study was to investigate the effects of initiation of sacubitril/valsartan vs enalapril treatment on objective measures of both waking activity and sleep in subjects with heart failure with reduced ejection…
- Trial name
- AWAKE-HF (NCT02970669)
- Testing
- sacubitril/valsartan (LCZ696), enalapril
- Where
- 23 sites in United States
- Volunteers
- 140 people
- Sponsor
- Novartis Pharmaceuticals
Paroxysmal Atrial Fibrillation, Cardiac Rhythm Disorder
Atrial Anomalies Predict Silent Atrial Fibrillation Detected by Implantable Cardiac Monitor in Cryptogenic Stroke
Cryptogenic stroke (CS) causes about 30% of admissions to a stroke unit. Silent paroxysmal atrial fibrillation (PAF) is believed to be the underlying cause of a significant proportion of patients.
- Conditions
- Paroxysmal Atrial Fibrillation, Cardiac Rhythm Disorder, Left Atrial Dilatation, Cryptogenic Stroke
- Trial name
- CRIPTO-FAST (NCT06542770)
- Testing
- Early implant of cardiac monitor
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Parc de Salut Mar
Non-Alcoholic Fatty Liver Disease
The Effect of Coenzyme Q10 on Endothelial, Vascular and Myocardial Function
Non-alcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular risk. The aim of this study is to investigate the effects of coenzyme Q10 (CoQ10) on endothelial, vascular and myocardial function in patients…
- Trial name
- NCT05941910
- Testing
- Q10
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
Pain
Gabapentin for Pain Management During Dilation and Evacuation
Justification. Pain control is still an issue for women undergoing second trimester abortion procedures. The investigators propose a randomized controlled double-blinded trial evaluating the use of adjunct gabapentin versus…
- Trial name
- Gabapentin (NCT03635905)
- Testing
- Gabapentin
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Sleep Apnea, Obstructive
Montelukast for Patients With Obstructive Sleep Apnea Syndrome
This study compares the effect of Montelukast vs Placebo on Flow Mediated Dilatation of the Brachial Artery (FMD) in patients with obstructive sleep apnea syndrome.
- Trial name
- MONTSAS (NCT03545997)
- Testing
- Montelukast 10mg
- Where
- 8 sites in France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Grenoble
Endothelial Dysfunction
A Clinical Trial for People HIV+ Age > 50 at Risk for Heart Disease
This research study is to see whether blood vessel function, an early sign of heart disease, improves in HIV-infected men and women who take telmisartan for 12 weeks.
- Trial name
- NCT01578772
- Testing
- Telmisartan
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Vascular Aging
Sodium Nitrite to Treat Arterial Aging
The proposed research will determine the effectiveness of nitrite, a naturally occurring compound in the body, for improving the health and function of arteries in middle-aged and older adults.
- Trial name
- NCT02022670
- Testing
- Sodium Nitrite
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Pancreatitis
Endoscopic Sphincterotomy vs. Balloon Dilation for Assessment of Pancreatitis
One of the major elements of successful endoscopic retrograde cholangiopancreatography ( ERCP) is the timely and uncomplicated cannulation of the common bile duct (CBD) .
- Trial name
- NCT02346448
- Testing
- endoscopic sphincterotomy, balloon dilatation for 3 minutes, balloon dilatation for 6 minutes
- Where
- 3 sites in Germany
- Volunteers
- 600 people
- Sponsor
- Helios Albert-Schweitzer-Klinik Northeim
Bicuspid Aortic Valve
Evaluation of Aortic Stiffness as a Prognostic Indicator of Aortic Dilatation in Patients With Bicuspid Aortic Valve by Multimodal Imaging
The objective is the development and validation of morphological markers informative of aortic dilatation in order to improve the precision of the risk of aneurysm of the thoracic aorta and of acute aortic syndrome for patients…
- Trial name
- IRM-BAO (NCT03474159)
- Testing
- Magnetic Resonance Imaging, Transthoracic echocardiography, Echography UltraFast
- Where
- France
- Volunteers
- 100 people
- Sponsor
- French Cardiology Society
Cervical Preparation Prior to Dilation and Evacuation
RCT of Cervical Ripening Double Ballon Catheter Prior to Dilation and Evacuation.
The purpose of this study is to determine whether the overnight use of an FDA-cleared CRDB catheter is superior to the use of overnight osmotic dilators as is standard of care cervical preparation for patients presenting for…
- Trial name
- CRDB RCT (NCT07200115)
- Testing
- Cervical Ripening Double Balloon (CRDB) Catheter, Osmotic Dilators
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Mucopolysaccharidosis IV A, Mucopolysaccharidosis VI
Evaluation of Losartan on Cardiovascular Disease in Patients With Mucopolysaccharidoses IV A and VI
Mucopolysaccharidoses (MPS) are multisystemic diseases with significant clinical overlap between their types, with cardiac problems being among the most commonly observed manifestations and are also among the main causes of…
- Conditions
- Mucopolysaccharidosis IV A, Mucopolysaccharidosis VI, Mucopolysaccharidoses, MPS IV A
- Trial name
- NCT03632213
- Testing
- Losartan
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Labor Pain
Epidural Analgesia in Different Cervix Diameter and the Rate of Cesarean Delivery
Epidural analgesia in the early stage of labor at cervix < 4.0cm was considered as a risk period for increasing the rate of cesarean delivery.
- Trial name
- EACDRCD (NCT00677274)
- Testing
- Epidural labor analgesia
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Nanjing Medical University
Cataract
Study of Intracameral Adrenaline for Pupil Dilation Without Topical Mydriatics in Refractive Cataract Surgery
The purpose of this study is to study the safety and efficacy of intracameral adrenaline for pupil dilation without topical mydriatics in refractive cataract surgery.
- Trial name
- NCT01264653
- Testing
- adrenalin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
Aortic Aneurysm, Athlete
Prevalence of Ascending Aortic Dilation in Sports Medicine
This study aims to assess the prevalence of ascending aortic dilation in athletes from the general population undergoing routine sports medicine evaluation.
- Trial name
- PRAADS (NCT07050953)
- Testing
- focused cardiac ultrasound
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Pain Management, Abortion
Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement
The purpose of this study is to improve pain management for participantswho need osmotic dilators for cervical preparation the day before their second trimester abortion procedure.
- Conditions
- Pain Management, Abortion, Second Trimester Abortion, Dilation and Evacuation
- Trial name
- PCB-KinD (NCT07487246)
- Testing
- Ketorolac, oral ibuprofen, Lidocaine HCl 1%
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Rush University Medical Center
Adhesive Capsulitis, Frozen Shoulder
Corticosteroids and / or Arthrographic Distention in the Treatment of Adhesive Capsulitis
Arthrographic distention of the shoulder joint is an increasingly popular treatment option in the management of patients with frozen shoulder.
- Trial name
- CADAC (NCT01983527)
- Testing
- Arthrographic distention, Intra-articular corticosteroid Depo Medrol
- Where
- Belgium
- Volunteers
- 132 people
- Sponsor
- Imelda Hospital, Bonheiden
Choledocholithiasis
Comparison of Papillary Balloon Dilatation Vs.Sphincterotomy for Lithotripsy in Difficult Sphincterotomy or Distal CBD Tapering
Compare endoscopic papillary balloon dilatation vs. endoscopic sphincterotomy for bile duct stones in: when sphincterotomy is difficult (periampullary diverticulum, prior sphincterotomy or Billroth II anastomosis) when there is…
- Trial name
- NCT00329888
- Testing
- Endoscopic papillary balloon dilatation, Endoscopic sphincterotomy
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital