Clinical trials: Distension
Overactive Bladder Syndrome, Voiding Dysfunction
Cystoscopy Plus Urethral Dilatation Versus Cystoscopy Alone in Women With Overactive Bladder Syndrome and Impaired Voiding
Urethral dilatation is a commonly undertaken intervention for a variety of urinary complaints including overactive bladder symptoms. There is however very little evidence for its efficacy, and no randomized trial evidence.
- Trial name
- NCT00839969
- Testing
- Cystoscopy, Cystoscopy and urethral dilatation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Medway NHS Foundation Trust
Coronary In-stent Restenosis
Restenosis Intrastent: Bioresorbable Vascular Scaffolds Treatment With Scoring Balloon Pre-dilatation (RIBS VI Scoring)
Treatment of patients with in-stent restenosis (ISR) remains a challenge. This study will assess the efficacy of Bioresorbable Vascular Scaffolds (BVS) (Abbott Vascular) in the treatment of patients suffering from ISR after…
- Trial name
- NCT03069066
- Testing
- Bioresorbable vascular scaffold. Absorb GT1 (Abbott)
- Where
- 10 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Spanish Society of Cardiology
Sickle Cell Disease
Evaluation of Non-invasive Endothelial Function in Children Sickle by Vascular Ultrasound
Sickle cell disease (SCD) is an inherited disorder characterized by recurrent painful crises with ischemia resulting from vascular occlusion.
- Trial name
- NCT02829580
- Testing
- Echocardiography
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Toulouse
Lung Disease,Obstructive
Airway Responsiveness in Patients With AECOPD Mechanical Ventilation by Inspiratory and Bronchial Dilation Testchronic Obstructive Pulmonary Disease
In the patients with COPD mechanical ventilation, the bronchial dilatation is very common. However, the evaluation of the efficacy of the medical examination and other subjective indicators, such as doctors, depends on the…
- Trial name
- NCT02592122
- Testing
- Salbutamol Aerosol, No drugs
- Where
- China
- Volunteers
- 120 people
- Sponsor
- snow
Coronary Artery Ectasia
Ischemia and Inflammatory Markers Among Patients With Coronary Artery Ectasia
study the ischemic burden in patients with CAE, and its relation to inflammatory markers. To assess the ischemic response during exercise ECG among patients with different variants of CAE.
- Trial name
- NCT05692115
- Testing
- stress ECG
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pre-induction Dilation of Cervix
Induction of Labor in Women With Unfavorable Cervix: Dilapan Versus Foley Bulb
Women undergoing mechanical cervical ripening for labor induction will be randomized to Dilapan-S® versus Foley bulb. The investigators hypothesized that osmotic cervical dilators (Dilapan-S®) are as effective as Foley bulb…
- Trial name
- NCT02899689
- Testing
- Dilapan, Foley Catheter
- Where
- 2 sites in United States
- Volunteers
- 419 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Menopause, Cardiovascular Diseases
A Longitudinal Study to Identify Mechanisms of Menopause on Cardiovascular Disease Risk
With the cessation of estrogen production at menopause, the risk of cardiovascular disease like arthrosclerosis, myocardial infarction and stroke increases dramatically.
- Conditions
- Menopause, Cardiovascular Diseases, Vascular Dilation, Physical Activity
- Trial name
- NCT05647876
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cardiovascular Diseases, Testicular Neoplasms
High-Intensity Aerobic Interval Training in Testicular Cancer Survivors
This study evaluates the impact of a supervised 12-week high-intensity aerobic interval exercise program (versus a self-directed exercise usual care group) on traditional and novel cardiovascular disease risk factors and…
- Trial name
- HIITTS (NCT02459132)
- Testing
- High-intensity aerobic interval exercise
- Volunteers
- 63 people
- Sponsor
- University of Alberta
Irritable Bowel Syndrome
The Effects of Added Enzyme α-Galactosidase at a Carbohydrate-rich Meal in Irritable Bowel Syndrome (IBS)
IBS (irritable bowel syndrome) is a functional gastrointestinal disorder which is characterized by recurrent pain and/or discomfort, altered stool form, and abdominal distension.
- Trial name
- NCT01483287
- Testing
- Alpha-Galactosidase
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Sahlgrenska University Hospital
Pre-hypertension
Study: Effects of Strawberries on Blood Pressure
The specific aim of the study is to determine whether a freeze dried powder provided by the California Strawberries Commission, can reduce blood pressure in patients with pre-hypertension.
- Trial name
- CSCBP (NCT01190319)
- Testing
- Strawberry Beverage
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Coronary Artery Disease
Treatment of Primary Coronary Artery Vascular Lesions With Biolimus Coated Coronary Balloon Dilation Catheter
The purpose of the study was to further evaluate the long-term safety and efficacy of the Biolimus Coated Coronary Artery Balloon Dilation Catheter in the real world.
- Trial name
- NCT06385067
- Testing
- Biolimus Coated Coronary Artery Balloon Dilation Catheter
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- JW Medical Systems Ltd
Post Operative Pain
Routine Cervical Dilatation at the Non-labour Caesarean Section and Its Influence on Postoperative Pain
Caesarean section is a common method of delivery in obstetrics. With the recent increase in the rate of this procedure, it is wise to understand and implement the optimal surgical technique.
- Trial name
- NCT03513237
- Testing
- Cervical dilation
- Where
- Egypt
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Epiphora, Conjunctivitis
Perforated Punctal Plugs for Treatment of Papillary Conjunctivitis in Otherwise Healthy Patients
Assessing efficacy of punctal dilatation with insertion of perforated punctal plugs for the management of acquired punctal stenosis due to allergic conjunctivitis in otherwise healthy patients.
- Trial name
- NCT02503956
- Testing
- Perforated Punctal plugs, Crawford tube insertion, Crawford lacrimal tube
- Where
- Israel
- Volunteers
- 14 people
- Sponsor
- Rabin Medical Center
Fetus in Posterior or Transverse Position; Manual Rotation ; Obstetrics ; Delivery Room Practice
Evaluation of the Impact of Rotating Posterior and Transverse Presentations At 2 Hours of Full Dilation
During labor, 20% of fetuses present in a posterior or transverse position. Among them, 90% rotate spontaneously during labor. For the remaining 10%, maintaining a posterior or transverse position leads to longer labor, increased…
- Trial name
- NCT06886854
- Testing
- Mode of delivery
- Where
- 2 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Hospices Civils de Lyon
Peripheral Arterial Disease, Fistula
A Study of Hemodialysis Arteriovenous Fistulae Stenosis Treated With APERTO
To evaluate the safety and efficacy of Paclitaxel Eluting Hemodialysis Shunt Balloon Dilatation Catheter (APERTO) compared with the Balloon Dilatation catheter (OHICHO II) for the treatment of Arteriovenous Fistulae Stenosis in…
- Trial name
- NCT02962141
- Testing
- Paclitaxel Releasing Peripheral Balloon Dilatation Catheter, Balloon Dilatation Catheter
- Where
- 9 sites in China
- Volunteers
- 161 people
- Sponsor
- ZhuHai Cardionovum Medical Device Co., Ltd.
Anorectal Disorder
The Guarding Reflex Anal, Study of the Modulation Function of Rectal Distension
The term Guarding Reflex refers to a progressive, involuntary increase in the external urethral sphincter activity during bladder filling.This is a mechanism of continence, preventing from unwanted urine leakage in situation of…
- Trial name
- NCT04409054
- Testing
- Cough and Valsalva effort
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Gérard Amarenco
Vasodilation
An Investigation of the Dose-dependent Vascualr Effects of (-)-Epicatechin in Healthy Men
Aim: To investigate the dose-dependent vascular effect (primarily using FMD) of 3 low-level doses of pure (-)-epicatechin ≤ 1 mg/kg BW (0.1, 0.5 \& 1.0 mg/kg BW) in healthy men.
- Trial name
- NCT02292342
- Testing
- Water, Epicatechin 0.1 mg/kg, Epicatechin 0.5 mg/kg
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Reading
Esophagectomy, No Signs of Cancer Recurrence
Pylorus Dysfunction After Esophagectomy and Gastric Tube Reconstruction. Effect of Pneumatic Pylorus Dilatation During Hospital Stay, Surgical Complications During in Hospital Stay
Delayed emptying of the gastric tube after esophagectomy is a frequent and durable problem. No treatment is currently available.
- Conditions
- Esophagectomy, No Signs of Cancer Recurrence, Delayed Gastric Emptying
- Trial name
- NCT02086461
- Testing
- Pneumatic pyloric dilatation, 15 mm pyloric balloon dilatation
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska University Hospital
Corneal Ectasia, Corneal Disease
Dresden Corneal Disease and Treatment Study
The purpose of this study is long-term follow up of patients with corneal diseases to analyze the quality of surgical interventions and diagnosis.
- Conditions
- Corneal Ectasia, Corneal Disease, Corneal Astigmatism, Keratoconus
- Trial name
- NCT04251143
- Testing
- corneal cross-linking, corneal topography and tomography
- Where
- Germany
- Volunteers
- 700 people
- Sponsor
- Technische Universität Dresden
Coronary Artery Disease
Effect of Garlic Tablet Some Indicators Related to Atherosclerosis
The purpose of this study is to determine whether garlic in adjunct to conventional medical treatment is effective in improving carotid intima media thickness (CIMT), Flow mediated dilation (FMD) and plasma lipid profile or…
- Trial name
- NCT01948453
- Testing
- Garlic
- Where
- Iran
- Volunteers
- 56 people
- Sponsor
- Shahid Beheshti University