Clinical trials: Distress, Psychological
Alcohol Use Disorder, Drug Use
A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users
Alcohol use is a significant problem among Latinxs and immigration-related stress increases risk for substance use. A theoretically-based cultural adaptation of motivational interviewing (CAMI) that specifically integrated…
- Conditions
- Alcohol Use Disorder, Drug Use, Psychological Distress
- Trial name
- CAMI-HI (NCT04771650)
- Testing
- CAMI
- Where
- 2 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Cognitive Remediation, Breast Cancer
Remediation for Mild Cognitive Deficits After Cancer
Cancer survival rates have improved significantly over the past decades and patients now experience a number of side effects including cancer-related cognitive impairment (CRCI): problems with memory, executive function…
- Trial name
- EURECA (NCT04808674)
- Testing
- Cognitive remediation program
- Where
- 2 sites in France
- Volunteers
- 24 people
- Sponsor
- Hospices Civils de Lyon
Type 1 Diabetes
Adaptation of REDCHIP Intervention for the Portuguese Context
The present Feasibility Randomized Controlled Trial (FRCT) aims to assess the acceptability and effectiveness of REDCHiP intervention, targeting parents of young children with T1D, followed in two major Portuguese hospitals.
- Trial name
- REDCHIP (NCT07201779)
- Testing
- REDCHiP, Treatment As Usual Control Group
- Volunteers
- 44 people
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Caregiver Stress, Caregiver Stress Syndrome
ACT Group for Family Caregivers of Stroke Survivors
The goal of this study is to evaluate the efficacy of group-based ACT intervention in improving the levels of psychological distress in caregivers of stroke survivors. The main questions it aims to answer are: 1.
- Conditions
- Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress
- Trial name
- NCT07528261
- Testing
- Group-based ACT Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Wright Institute
Depression, Psychological Distress
Behavior, Biology and Well-Being Study
The central aim of this study is to test the efficacy of the Healthy Minds Program (HMP) app, an intervention designed to promote well-being.
- Trial name
- BeWell (NCT05183867)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 1,157 people
- Sponsor
- University of Wisconsin, Madison
Psychological Distress
Ensuring Quality in Psychological Support-Foundational Helping Skills
There is lack of feasible and effective curricula that can rapidly be taught on basic mental health and psychosocial helping skills.
- Trial name
- EQUIP-FHS (NCT04511156)
- Testing
- Foundational Helping Skills
- Where
- 3 sites in Nepal, Peru and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- George Washington University
Depressive Symptoms, Depression, Anxiety
Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness
Psychological and existential distress are a common cause of suffering among patients nearing the end of life, and a major reason for requesting medical aid in dying.
- Conditions
- Depressive Symptoms, Depression, Anxiety, Psychological Distress, Terminal Illness
- Trial name
- NCT04257227
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Ottawa Hospital Research Institute
Relapse Rates Related to Website Usage
Web-based Support for People With Schizophrenia and Their Families
This study will assess the feasibility of using the internet and in-home computers to provide advice from health care professionals, social support, and health information to people with schizophrenia and their families.
- Trial name
- NCT00177983
- Testing
- (relapse rate)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Acute Ischemic Stroke, Biofeedback
Effects of Biofeedback in Patients With Acute Cerebral Infarction
The major aim of this study is to investigate the effects of biofeedback assisted abdominal breathing training on improving the psychological and physiological distress in patients with ACI.
- Conditions
- Acute Ischemic Stroke, Biofeedback, Autonomic Dysfunction, Cognitive Function, Psychological Distress
- Trial name
- NCT03516227
- Testing
- heart rate variability biofeedback
- Volunteers
- 40 people
- Sponsor
- National Defense Medical Center, Taiwan
Chronic Knee Pain
Effects of iCBT and Exercise for Chronic Knee Patients
The goal of this clinical trial is to study the effects of using an internet-based cognitive behavioural therapy (iCBT) program and exercise in chronic knee patients with psychological distress.
- Trial name
- iCBT (NCT06133738)
- Testing
- Standardized Exercise Program, Internet based Cognitive Behavioral Therapy, Educational Materials
- Volunteers
- 40 people
- Sponsor
- University of Bahrain
Central Nervous System Cancer, Psychological Distress
Interest of a TEteleconsultation of a Psychological Support Nurse on Psychological Distress in Patients With a Primary Malignancy of the Central Nervous System
The goal of this clinal trial is to compare the effectiveness of nurse-led teleconsultation with usual care (intervention group) on psychological distress in patients with primary malignant tumors of the central nervous system…
- Trial name
- TECAP (NCT06485310)
- Testing
- Teleconsultation for psychological support
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Group-based, Self-Help Plus (SH+)
Examining the Effect of a Group-Based Stress Management Course on Empowering the Mental Health of Medical Faculty Students and Resident Physicians: A Randomized Controlled Study
Physicians and medical students have higher rates of depression, anxiety, burnout, and suicide risk than the general population, and this disparity often begins early, even during medical school.
- Conditions
- Group-based, Self-Help Plus (SH+), Psychoeducational Intervention, Stress Management Course
- Trial name
- EMPOWER-MD (NCT07679503)
- Testing
- self help plus
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Eskisehir Osmangazi University
Psychological Distress
Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)
About 30-50% of patients with advanced illness experience depression, anxiety, or decreased sense of purpose and autonomy. Together, these are called psychological distress.
- Trial name
- NCT07063862
- Testing
- Psilocybin
- Where
- 7 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Bruyère Health Research Institute.
Massage Therapy, Health-care Workers
Can Massage During One Year Improve Health in Health-care Providers Working in Hospital
The overall aim of this pilot study is to investigate the effect, "feasibility" and experiences of regular massage over 12 months on the mental and physical health of healthcare professionals, as well as the frequency of layoffs…
- Conditions
- Massage Therapy, Health-care Workers, Quality of Life, Psychological Distress
- Trial name
- NCT05555082
- Testing
- Massage
- Where
- 2 sites in Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Post Traumatic Stress Disorder, Family
Psychological Impact in a Relative, Following the Announcement of the Death of a Loved One After Cardiac Arrest and the Early Request for Organ Donation
The fight against the scarcity of grafts is a major public health issue in France. Despite a very good success rate of transplants from brain-dead donors or living donors, the waiting time for transplantation continues to…
- Conditions
- Post Traumatic Stress Disorder, Family, Psychological Distress, Organ and Tissue Procurement
- Trial name
- REPERPSY (NCT03721770)
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- frederic ADNET
Kidney Failure, Chronic, Depression
Intervention for Improving Psychological Distress in Dialysis
To explore whether it is feasible to recruit and retain haemodialysis patients into a randomised controlled trial of online cognitive-behavioural therapy to manage distress
- Conditions
- Kidney Failure, Chronic, Depression, Anxiety
- Trial name
- iDiD (NCT02352870)
- Testing
- Computerised Cognitive Behavioural Therapy, Telephone support
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- King's College London
Caregiver Distress, Emotional Distress
The Coma Family Program (COMA-F): A Resilience Program for Caregivers of Patients With Severe Acute Brain Injury
The purpose of this research study is to determine whether COMA-F is more efficacious at reducing emotional distress in caregivers of patients with severe acute brain injuries, compared to health education control.
- Conditions
- Caregiver Distress, Emotional Distress, Caregivers, Resilience
- Trial name
- COMA-F (NCT07331324)
- Testing
- Coma Family Program 1, Coma Family Program 2
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Psychological Distress
Preventing Premature Family Maladjustment: an e-Health Interdisciplinary Research
The consequences of preterm birth extend beyond the clinical conditions of the newborn, profoundly impacting the functioning and well-being of families.
- Trial name
- e-ParWelB (NCT06495762)
- Testing
- e-health assesment
- Where
- 6 sites in Italy
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Cancer
Impact of Group Psychological Interventions on Extracellular Vesicles in People Who Had Cancer
Background: There is some evidence demonstrating the effect of psychological interventions in improvements in health biological parameters.
- Trial name
- MindGAP-P (NCT04298398)
- Testing
- Mindfulness Based-Cognitive Therapy (MBCT), Emotion Focused Therapy Group for Cancer Recovery (EFT-CR), Treatment as usual (no intervention)
- Volunteers
- 108 people
- Sponsor
- Instituto Portugues de Oncologia, Francisco Gentil, Porto
Sexual Dysfunctions, Psychological, Uterine Cervical Neoplasms
A Randomized Controlled Trial of an Online Support Group for Sexual Distress Due to Gynecologic Cancer
There is a high prevalence of sexual and body image problems among women treated for gynecologic cancer, which can lead to considerable distress.
- Conditions
- Sexual Dysfunctions, Psychological, Uterine Cervical Neoplasms, Ovarian Neoplasms, Uterine Neoplasms
- Trial name
- NCT01654458
- Testing
- GyneGals Support Group
- Where
- 7 sites in United States, Canada
- Volunteers
- 398 people
- Sponsor
- Women's College Hospital