Clinical trials: Disturbed Sleep
Sleep Disturbance, Sleep Patterns
Probiotics on Sleep Among Adults Study
The aim of this study is to determine the impact of a probiotic formulation on subjective sleep patterns. It is hypothesized that participants given the probiotics will improve their sleep patterns compared to participants…
- Trial name
- NCT04767997
- Testing
- Probiotic formulation
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Sleep Initiation and Maintenance Disorders
Disturbed Sleep Model Study.
Subjects will be screened within 28 days. Each treatment session will consist of 2 PSG nights, study drug administration and noise model is conducted on second night.
- Trial name
- NCT00440323
- Testing
- SB-649868, Zolpidem
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sleep, Sleep Disturbance
Radicle Rest 24: A Study of Health and Wellness Products on Sleep and Related Health Outcomes
A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on sleep and related health outcomes.
- Conditions
- Sleep, Sleep Disturbance, Sleep Disorder
- Trial name
- NCT06347744
- Testing
- Radicle Rest Active Study Product 1.1 Usage, Radicle Rest Active Study Product 2.1 Usage
- Where
- United States
- Volunteers
- 1,646 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Sleep Problems
Assessment of the Pharmacokinetics of Circadin® in Children With Neurodevelopmental Disorders and Sleep Disturbances
There is increasing evidence that chronic sleep disorders in children with autism spectrum disorder (ASD), Angelman Syndrome (AS) and Smith-Magenis syndrome (SMS) are associated with disturbed melatonin secretion and melatonin…
- Trial name
- NCT01903681
- Testing
- Circadin 2 mg, Circadin 10 mg
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Insomnia, Sleep
Online Insomnia Treatment Program
The purpose of this study is to investigate improvements in sleep by comparing two 6-week digital programs, either online or app-based, that deliver Cognitive Behavioral Therapy for Insomnia (CBT-I), the "gold standard" treatment…
- Conditions
- Insomnia, Sleep, Sleep Disturbance, Sleep Disorder
- Trial name
- NCT05778812
- Testing
- Full Sleep, Path to Better Sleep
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Koko Home, Inc.
Seasonal Allergic Rhinitis
Mometasone Furoate on Sleep Disturbances in Subjects With Seasonal Allergic Rhinitis (Study P04608) (COMPLETED)
This study will hope to show that by relieving the participant's nasal symptoms of seasonal allergies using mometasone furoate nasal spray, the participant will obtain a better quality of night-time sleep, which in turn, causes…
- Trial name
- NCT00358527
- Testing
- Mometasone Furoate Nasal Spray (MFNS)
- Volunteers
- 401 people
- Sponsor
- Organon and Co
Adolescent Behavior, Sleep Disturbance
Personalized Approach To Habits - Sleep
Two arm study, intervention and control, to explore the impact of an app to help high risk teens with asthma improve their sleep
- Conditions
- Adolescent Behavior, Sleep Disturbance, Asthma in Children, Knowledge, Attitudes, Practice
- Trial name
- PATH-S (NCT07029919)
- Testing
- PATH-S app
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- KDH Research & Communication
Sleep Disturbance, Poor Sleep Quality
A Trial to Examine the Efficacy of a Supplement Gummy to Improve Sleep Quality and Quantity
This single-group trial evaluates the efficacy of FlavCity's Sleep Gummy supplement on sleep health in adults aged 20-50 who self-report issues with sleep.
- Conditions
- Sleep Disturbance, Poor Sleep Quality, Insomnia (Self-reported, Non-diagnosed)
- Trial name
- NCT07781332
- Testing
- Sleep Gummy Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- DTBE, LLC dba FlavCity
Sleep Disturbance
Comparison of the Natural Frequencies Technology Sleep Patches to Sham Patches During Sleep in the Home Environment
Prospective, randomized crossover study to compare the NFT sleep patches to sham device to assess sleep via home sleep testing device in the home environment
- Trial name
- NCT03205631
- Testing
- Natural Frequency Patch
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IC-IT Sciences Inc.
Autism Spectrum Disorder
Efficacy and Safety of Slenyto for Insomnia in Children With ASD
This is a randomized placebo controlled study in children diagnosed with autism spectrum disorder (ASD), to Investigate the Efficacy and Safety of Slenyto® to alleviate Sleep Disturbances in these children. .
- Trial name
- ASD (NCT04233502)
- Testing
- Melatonin
- Sponsor
- Neurim Pharmaceuticals Ltd.
Sleep Disturbances in Smith-Magenis Syndrome
Development of Clinical Database of Individuals With Smith-Magenis Syndrome and Sleep Disturbances
This database will be used to better understand the sleep problems of people with SMS. This clinical database will be a part of a larger Smith-Magenis Patient Registry used to create an awareness campaign around SMS and the sleep…
- Trial name
- NCT03154697
- Testing
- Data collection of sleep disturbances in individuals with SMS
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Vanda Pharmaceuticals
Posttraumatic Stress Disorder (PTSD), Sleep Disturbances and Insomnia
A Study to Evaluate Effects on Sleep and Safety of RE03 in PTSD Patients With Sleep Disturbances
Post-traumatic stress disorder (PTSD) affects many people who have experienced traumatic events. A common issue with PTSD is severe sleep disturbances, such as nightmares.
- Trial name
- PTSD-PoC (NCT06685965)
- Testing
- RE03
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Reconnect Labs
Sleep Initiation and Maintenance Disorders
The Ability of Songha Night ® to Improve Sleep in Patients With Mild to Moderate Sleep Disturbances
To evaluate the effect of Songha Night ® on insomnia, anxiety and quality of life compared to placebo in patients with mild to moderate insomnia.
- Trial name
- NCT02183714
- Testing
- Songha Night ®
- Volunteers
- 146 people
- Sponsor
- Boehringer Ingelheim
Sleep, Sleep Disturbance
Sounds Locked to ElectroEncephalogram Phase For the Acceleration of Sleep Onset Time
This study seeks to test whether auditory stimulation delivered at specific phases of the alpha oscillation (as measured by electroencephalogram) can accelerate sleep onset.
- Trial name
- SLEEPFAST (NCT05743114)
- Testing
- Elemind Neuromodulation (ENMod)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Elemind Technologies, Inc.
Post-Traumatic Stress Disorder
Carvedilol Versus Placebo for Treatment in Post Traumatic Stress Disorder (PTSD)
The investigators hypothesize that carvedilol, at less then therapeutic doses for cardiac effect, will reduce symptoms of Post Traumatic Stress Disorder.
- Trial name
- NCT01221792
- Testing
- Carvedilol
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Columbia Northwest Pharmaceuticals
Sleep Disturbance
A Study to Evaluate the Efficacy of UP165 on Sleep Quality and Mood State in Healthy Adults
A randomized, double blind, placebo controlled, parallel group study to evaluate the efficacy of UP165 on sleep quality and mood state in healthy adults
- Trial name
- NCT05821049
- Testing
- UPI65 (Low Dose), UP165 (High Dose)
- Where
- 6 sites in India
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Restless Legs Syndrome (RLS), Restless Legs Syndrome
12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome
The purpose of this study is to assess the efficacy and safety of ropinirole CR-RLS in the treatment of patients with Restless Legs Syndrome and associated sleep disturbance and period limb movements during sleep.
- Trial name
- (CR-RLS) (NCT00373542)
- Testing
- ropinirole CR-RLS
- Where
- 45 sites in United States
- Volunteers
- 39 people
- Sponsor
- GlaxoSmithKline
Fatigue, Stress
The U.S. Embryologist Fatigue Study
The purpose of the study is to determine physical and mental health issues of U.S. embryologists related to their occupational characteristics, and how workplace fatigue and burnout may affect their quality of life, cynicism…
- Conditions
- Fatigue, Stress, Burnout, Professional, Musculoskeletal Pain
- Trial name
- FUSE (NCT05326802)
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- TMRW Life Sciences
Sleep Hygiene, Sleep Disturbance
Effects of a Novel Supplement on Sleep, Metabolism, Body Composition and Performance
This study aimed to investigate the effects of a novel dietary supplement, consisting of melatonin and magnesium in a pod (coffee machine capsule) format, on sleep quality, stress, mood, sleepiness, biological rhythms…
- Trial name
- 4BETTSLEEP (NCT05236504)
- Testing
- Melatonin and magnesium-containing pod
- Where
- Portugal
- Volunteers
- 35 people
- Sponsor
- Bettery S.A.
Gastroesophageal Reflux Disease (GERD)
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disease (GERD)
This study includes patients with sleep disturbances associated with gastroesophageal reflux disease (GERD) and has 3 treatment arms.
- Trial name
- NCT00628342
- Testing
- Esomeprazole
- Volunteers
- 600 people
- Sponsor
- AstraZeneca