Clinical trials: Disturbed Sleep
Thoracic Surgical Procedures
Sodium Oxybate for Postoperative Sleep Disturbance After Thoracic Surgery
This is a single-center, randomized, double-blind, placebo-controlled trial. Three hundred-sixty adult patients undergoing elective thoracoscopic surgery will be randomly allocated at a 1:1 ratio to receive either intraoperative…
- Trial name
- NCT07794982
- Testing
- sodium oxybate
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Jingsheng Lou
Multiple Sclerosis, Sleep Disturbance
Reliability and Validity of the Turkish Version of General Sleep Disturbance Scale (GSDS-T) in Multiple Sclerosis
The GSDS-T was developed by Lee KA to assess difficulty falling asleep, waking up during sleep, sleep quality, and daytime alertnes.
- Trial name
- NCT06875908
- Testing
- Turkish Validity and Reliability of The GSDS-T in patients with multiple sclerosis
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Chronic Otitis Media With Effusion, Sleep Disturbances
The Effect of Tympanostomy Tube Insertion on Sleep in Children With Chronic Otitis Media With Effusion
The purpose of this study is to investigate the prevalence of sleep disturbances in children with Chronic Otitis Media with Effusion (COME) and the effect of tympanostomy tube insertion (TTI) on sleep disturbances.
- Trial name
- NCT02477735
- Testing
- Actigraphy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
OSA - Obstructive Sleep Apnea
Effects of Eszopiclone and Lemborexant in People With OSA With a Low Arousal Threshold Who Have Difficulty Sleeping
Insomnia and obstructive sleep apnoea (OSA) are very common conditions, collectively estimated to affect 2 billion people globally, and share many of the same symptoms.
- Trial name
- ELOSA (NCT06928766)
- Testing
- Eszopiclone 3 mg, Lemborexant 10mg
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Flinders University
Postoperative Cognitive Abilities
Postoperative Sleep Disturbances Role in Cognitive Test Results After Fast-track Hip and Knee Arthroplasty
The purpose of this study is to evaluate sleep cycle before and after fast-track arthroplasty (3 days before and 10 days after) combined with cognitive testing preoperatively, on postoperative day 1,2,10.
- Trial name
- NCT01383369
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sleep Disturbance, Sleep
Sleep and Circadian Interventions for College Students at High Risk of Suicide
The purpose of this study is to examine the extent to which delivering sleep and circadian focused interventions in addition to evidenced based psychiatric care for depression and suicide risk may contribute to decreasing suicide…
- Conditions
- Sleep Disturbance, Sleep, Depression, Suicide
- Trial name
- REST-UP (NCT07346014)
- Testing
- Sleep Feedback + Psychoeducation, Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+), Triple Chronotherapy (TCT+)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Pittsburgh
Poor Sleep Quality, Leg Cramps, Nocturnal
The Effect of a Daily Magnesium and Melatonin Supplement on Sleep Quality in People With Nighttime Leg Cramps
Participants are being invited to take part in a research study. Before deciding whether to take part, it is important for participants to understand why the research is being done and what it will involve.
- Conditions
- Poor Sleep Quality, Leg Cramps, Nocturnal, Melatonin, Magnesium
- Trial name
- MISIT (NCT07651514)
- Testing
- Magnesium and melatonin based multi-ingredient dietary supplementation
- Where
- 7 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- StudySetGo
Supraspinatus Injury, Sleep Disturbance
Conservative Treatment in Patients With Supraspinatus Tendon Injury.
Rotator cuff injuries are a major cause of severe pain, often significantly impacting patients\' sleep quality. For patients waiting for surgery or those not eligible for operative treatment, conservative treatment is…
- Trial name
- NCT06631976
- Testing
- 1ml of Depo-Medrol® injection, Rehabilitation, Nerve block with 4ml of 2% lidocaine
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Lodz
Burning Mouth Syndrome
A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome
This is a case control study of the association between burning mouth syndrome and sleep dysfunction. Cases will comprise of patients diagnosed with burning mouth syndrome at the UCSF oral medicine clinic.
- Trial name
- NCT00862576
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, San Francisco
Alcohol Dependence, Insomnia
Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence
Insomnia and other sleep abnormalities are common, persistent, and associated with relapse in alcohol-dependent patients. The overall, long-term objectives of the proposed research are to investigate the neurophysiologic…
- Trial name
- MA (NCT01014533)
- Testing
- Gabapentin dispensed to subject.
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Dr. Kirk Brower
Migraine, Sleep Disturbance
The Effect of Bright Light Therapy on Migraine With Sleep Disturbance
Migraine is a common disabling disorder and its substantial burden is associated with considerable negative impact on quality of life.
- Trial name
- NCT04890691
- Testing
- Feel Bright Light
- Volunteers
- 60 people
- Sponsor
- Hungkuang University
Persistent Lower Back Pain, Sleep Disturbance
What Are Persistent Lower Back Pain Patients' Views of Sleep Health Within an Outpatient Musculoskeletal Physiotherapy Setting?
The goal of this qualitative is to understand the views and opinions of patients with persistent lower back pain patients who are awaiting physiotherapy treatment with regards sleep their sleep health.
- Conditions
- Persistent Lower Back Pain, Sleep Disturbance, Lower Back Pain, Chronic Low-back Pain
- Trial name
- NCT06094517
- Testing
- Interview
- Volunteers
- 10 people
- Sponsor
- Sheffield Hallam University
Post Traumatic Stress Disorder, Rape Sexual Assault
Early Psychological Intervention After Rape
Rape is a common cause of post-traumatic stress disorder (PTSD) among women, as around 30-50% will develop PTSD in the aftermath of rape.
- Conditions
- Post Traumatic Stress Disorder, Rape Sexual Assault, Sexual Dysfunctions, Psychological, Pelvic Floor Myalgia
- Trial name
- EIR (NCT05489133)
- Testing
- Modified prolonged exposure
- Where
- 4 sites in Norway
- Volunteers
- 166 people
- Sponsor
- St. Olavs Hospital
Stress Disorders, Post-Traumatic
A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD
This randomized, double-blind, placebo-controlled trial of doxazosin will assess doxazosin's effectiveness for PTSD nightmares, subjective sleep quality, and non-nightmare PTSD symptoms in adult men and women veterans with full…
- Trial name
- NCT03339258
- Testing
- Doxazosin Mesylate, Extended Release
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
Autism Spectrum Disorder
Clonidine for Sleep Disturbances in Children With Autism Spectrum Disorder
Sleep disturbance has been reported in 44-86% of children with autism spectrum disorder (ASD) and is the source of considerable stress for the affected individual and family.
- Trial name
- NCT02812368
- Testing
- Clonidine
- Where
- United States
- Sponsor
- Ohio State University
Breast Cancer
Epigenetics and Psychoneurologic Symptoms in Women With Breast Cancer
This study examines the relationship among epigenetic alterations and the development and persistence of psychoneurologic symptoms (cognitive dysfunction, depressive symptoms, anxiety, fatigue, sleep disturbance, and pain) in…
- Trial name
- NCT01411943
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Virginia Commonwealth University
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Hot Flashes, Night Sweats
Applied Relaxation (AR) Technique Versus Its Modified Version for Treating Menopausal Symptoms
The purpose of this study is to demonstrate better efficacy and effectiveness of modified applied relaxation technique over its original version for treating menopausal symptoms.
- Conditions
- Hot Flashes, Night Sweats, Sleep Disturbances
- Trial name
- NCT01429636
- Testing
- Modified Relaxation (MR), Applied Relaxation (AR)
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Chiang Mai University
Anorexia Nervosa, Sleep Disorders in Children
Pediatric Prolonged-Release Melatonin for Sleep Disturbances in Children and Adolescents With Anorexia Nervosa (MELSom-ANOREXIA)
Sleep disturbances are reported by more than 50% of patients with Anorexia Nervosa (AN) and are associated with increased AN severity, psychiatric comorbidities, and poorer quality of life.
- Trial name
- MELSomAnorexia (NCT07576764)
- Testing
- Pediatric Prolonged-Released Melatonin (PedPRM)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Critical Illness, Delirium
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
Up to 25% of intensive care unit (ICU) survivors experience cognitive impairment comparable in severity to mild Alzheimer's disease and related dementias after hospital discharge.
- Conditions
- Critical Illness, Delirium, Cognitive Impairment, Cognitive Decline
- Trial name
- SLEEP-COG (NCT06411561)
- Testing
- SLEEP + COG, COG, SLEEP
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington