Clinical trials: Disturbed Sleep
Cancer, Sleep Disturbance
Wellness App for Sleep Disturbance in Hematological Cancer Patients
In a randomized controlled trial (RCT), the investigators will recruit participants to an 8-week "app-based wellness" intervention, followed by a 12-week follow-up period.
- Conditions
- Cancer, Sleep Disturbance, Anxiety, Depression
- Trial name
- Heme (NCT05294991)
- Testing
- Wellness app intervention #1, Wellness app intervention #2
- Where
- 3 sites in United States
- Volunteers
- 276 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Sleep Disturbance, Fatigue Syndrome, Chronic
Bao Yuan Tang Extract and Galactooligosaccharides for Sleep Regulation
Certain classical formulas in traditional Chinese medicine and dietary prebiotics have demonstrated beneficial effects on various aspects of suboptimal health status in previous studies.
- Conditions
- Sleep Disturbance, Fatigue Syndrome, Chronic, Endocrine Disorder, Glucose Metabolism Disorder
- Trial name
- NCT07774897
- Testing
- Combination product (Bao Yuan Tang full-component extract 2.0g and galactooligosaccharides 2.0g), Galactooligosaccharides 2.0g
- Where
- 6 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Cancer, Circadian Rhythm Disorders
Identifying Circadian Rest-Activity Rhythm Disorders in Patients With Advanced Cancer
Circadian rest-Activity Rhythm disorders (CARDs) are common in patients with cancer, particularly in advanced disease. CARDs are associated with increased symptoms, poorer quality of life, poorer response to anticancer treatments…
- Conditions
- Cancer, Circadian Rhythm Disorders, Sleep Disturbance, Activity, Motor
- Trial name
- NCT06023654
- Where
- 2 sites in Ireland
- Volunteers
- 100 people
- Sponsor
- University of Dublin, Trinity College
Sleep Disturbance
Perioperative Lignocaine and Sleep Disturbance
The aim of this clinical trial is to study the effect of an intravenous infusion of lidocaïne in a multimodal analgesic protocol on the architecture sleep during the first postoperative night.
- Trial name
- NCT03317912
- Testing
- Lidocaïne 2%
- Volunteers
- 40 people
- Sponsor
- University of Liege
Bullous Pemphigoid (BP)
Prevalence of Sleep Disturbances in Bullous Pemphigoid Patients.
Bullous pemphigoid (BP) is the most common autoimmune blistering disorder. The incidence of BP has increased due to increased life expectancy, particularly in developed countries, which can be associated with multiple geriatric…
- Trial name
- SLEEP-BP (NCT07188402)
- Testing
- Prevalence of sleep disturbances in patients with bullous pemphigoid, Prevalence of sleep disturbances in healthy volunteers without bullous pemphigoid
- Where
- France
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Insomnia, Sleep Disturbance
Improving Sleep to Prevent Depression & Anxiety in Adolescents at High Risk
Emerging evidence has shown that sleep interventions such as Cognitive Behavioral Therapy for Insomnia (CBT-I) improve depressive and anxiety symptoms in adults, even when the intervention is brief, such as four to six sessions.
- Conditions
- Insomnia, Sleep Disturbance, Depressive Symptoms, Anxiety Symptoms
- Trial name
- NCT06358495
- Testing
- Cognitive Behavioral Therapy for Insomnia, Active Control
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Cognitive Dysfunction, Insomnia
Sleep Disturbance in MCI: A Study of a Cognitive Behavioural Therapy Digital Intervention
This study aims to determine the feasibility of a randomized-controlled trial of digital cognitive behavioural therapy for insomnia (CBT-I) for sleep and cognitive performance in older adults with MCI and insomnia symptoms (50-80…
- Conditions
- Cognitive Dysfunction, Insomnia, Mild Cognitive Impairment, Cognitive Disorder
- Trial name
- SUCCEED (NCT05568381)
- Testing
- digital CBT-I, Online Sleep Health Education package
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- University of Sydney
Neoplasm of Breast (Disorder), Carcinoma of Prostate (Disorder)
An Observational Prospective Cohort Study Using an Actigraphy Device.
This study focuses on whether or not physical activity and sleep quality correlate with the health of prostate and breast cancer patients.
- Trial name
- NCT03475433
- Testing
- Actigraphy device
- Where
- 2 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University
Anxiety, PTSD
Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health
RESYNC-BH is a research study evaluating a personalized, non-drug brain-and-body treatment approach for adults with ongoing behavioral health symptoms such as depression, anxiety, trauma-related symptoms, sleep problems…
- Conditions
- Anxiety, PTSD, ADHD, Depression Disorders
- Trial name
- RESYNC-BH (NCT07812987)
- Testing
- AIP-Informed Integrative Psychotherapy, Transcutaneous Auricular Vagus Nerve Stimulation, Regulated Breathing and Autonomic Regulation
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Tactical Mind Research Coalition, Inc.
The Role of the LC-NA System in Sleep Regulation
The Role of the LC-NA System in Experimental Sleep Fragmentation
Sleep-wake regulation affects every person's life, yet the molecular mechanisms underlying these processes remain poorly understood.
- Trial name
- DMTN_FragSleep (NCT07167316)
- Testing
- DMTN, Auditory Stimulation, Placbo
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hans-Peter Landolt
Sleep Disturbance, Postmenopausal Symptoms
Sleep and Quality of Life Among Postmenopausal Women
The purpose of this study is to assess the sleep quality and quality of life of the study population.
- Trial name
- NCT05634668
- Testing
- Interviewing sheet
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Chronic Pain
Chronic Pain After Combat-Related Traumatic Brain Injury (cTBI-Pain Study) A Prospective Cohort Study of Pain Chronification After Combat-Related Traumatic Brain Injury
Combat-related traumatic brain injury (cTBI), particularly blast-related injury, is frequently associated with the development of persistent and disabling chronic pain.
- Conditions
- Pain, Chronic Pain, Chronic Pain Due to Injury
- Trial name
- TBI-Pain (NCT07424248)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Hepatic Encephalopathy, Covert Hepatic Encephalopathy
Affect of Melatonin on Sleep and Cognition in Cirrhosis
The goal of this clinical trial is to learn the affect of melatonin on sleep, cognitive function, and quality of life (QoL) in patients with cirrhosis and a complication called hepatic encephalopathy (HE).
- Conditions
- Hepatic Encephalopathy, Covert Hepatic Encephalopathy, Cirrhosis, Sleep Disturbances and Insomnia
- Trial name
- SNORE-HE (NCT07046429)
- Testing
- Melatonin tablet 3 mg once daily, Thiamine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Weill Medical College of Cornell University
Sleep Disturbance, Trauma
Treatment for Sleep Disturbance in Orthopaedic Trauma Patients
The purpose of the study is to test the efficacy of sleep treatment in human patients following traumatic injury. Specifically, the study will determine if treatment consisting of melatonin and education related to sleep habits…
- Trial name
- NCT03779243
- Testing
- Melatonin 5mg and Sleep Education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stanford University
Anxiety, Depression
Online Positive Psychology Intervention for Depression and Anxiety Due to COVID-19
This study evaluates the effectiveness of a Positive Psychology intervention, that is focused on increasing the positive emotions and strengths of human beings.
- Conditions
- Anxiety, Depression, Sleep Disturbance
- Trial name
- NCT04468893
- Testing
- Online Intervention Mental Health COVID-19
- Where
- Mexico
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Sleep Initiation and Maintenance Disorders, Osteoarthritis
Sleep in Osteoarthritis Project
Osteoarthritis (OA) is one of the most common diseases and one of the leading causes of disability in the world. People with OA frequently experience sleep disturbances, primarily due to pain.
- Trial name
- SOAP (NCT00592449)
- Testing
- Cognitive behavioral therapy (CBT) for insomnia, Behavioral desensitization treatment for insomnia
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Shift-Work Related Sleep Disturbance, Sleep Deprivation
Light Intervention for Adaptation to Night Work
The project will contribute with new knowledge concerning how aspects of the physical work environment (lighting conditions) can be arranged to facilitate the workers' adaptation to night work.
- Conditions
- Shift-Work Related Sleep Disturbance, Sleep Deprivation, Sleep
- Trial name
- NCT03203538
- Testing
- LED-light, 1000 lux, LED-light, 100 lux, LED-light, 7000 K
- Where
- Norway
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Sleep, Sleep Disturbance
An Exploratory Investigation of a Supplement to Enhance Sleep Quality and Quantity
This double-blind study will examine the effectiveness of Dream Powder and Dream Powder Extra Strength over a six week period. The main outcomes of interest will be sleep quantity and quality, as well as self-reported changes in…
- Conditions
- Sleep, Sleep Disturbance, Sleep Hygiene
- Trial name
- NCT05521243
- Testing
- Beam Organics Dream Powder, Beam Organics Dream Powder Extra Strength
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Beam
Delirium, Sleep Disturbance
De-escalating Vital Sign Checks
The overall goals for this study are: 1) to develop a predictive model to identify patients who are stable enough to forego vital sign checks overnight, 2) incorporate this predictive model into the hospital electronic health…
- Trial name
- NCT04046458
- Testing
- Nighttime Vital Sign EHR Alert, No EHR alert
- Where
- United States
- Volunteers
- 1,436 people
- Sponsor
- University of California, San Francisco
Depressive Disorder, Sleep Disturbance
iACT & iTBS for Sleep Quality in Depressed Adolescents
This study evaluated whether combining an internet-delivered Acceptance and Commitment Therapy program with intermittent theta burst stimulation improves subjective sleep quality in adolescents with depressive disorders and sleep…
- Trial name
- NCT07807072
- Testing
- Internet-Delivered Acceptance and Commitment Therapy, Intermittent Theta Burst Stimulation
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Central China Normal University