Clinical trials: Disturbed Sleep
Sleep, Sleep Disturbance
Impact of Bedtime Routines on Sleep and Development in Toddlers
Investigators will recruit up to 100 families (children aged 12.0 to 14.9 months and their primary caregivers) at their scheduled 12-month well child care infant visit at Temple Pediatric Care.
- Conditions
- Sleep, Sleep Disturbance, Child Development
- Trial name
- NCT04592172
- Testing
- Bedtime Routine Education
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Saint Joseph's University, Philadelphia
Alcoholism
Trazodone for Sleep Disturbance in Early Alcohol Recovery
This study is a randomized, double-blind clinical trial comparing trazodone (Desyrel) and placebo among sleep-disturbed, alcohol-dependent individuals shortly after discharge from an inpatient detoxification program.
- Trial name
- SIESTA (NCT00027053)
- Testing
- Trazodone
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Rhode Island Hospital
Chronic Pain
Chronic Pain and Assessment of Sleep
Sleep impairments reliably predict worsened chronic pain and correlate with visual analogue pain scores. Therapies targeted at improving sleep, including cognitive behavioral therapy, improve both sleep quality and also pain…
- Trial name
- NCT02969434
- Testing
- Sleep assessment tools
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- University of Aberdeen
Sleep, Sleep Disorders
The BEST Study: The Efficacy of Brain Entrainment Sleep Technology in Military Healthcare Beneficiaries
Brain Entrainment Technology (BET), also known as Binaural Beat Technology (BBT); is an auditory-neurophysiologic technique which uses auditory tones (often embedded in music, nature sounds or white noise) dichotically via stereo…
- Conditions
- Sleep, Sleep Disorders, Sleep Deprivation, Sleep Disturbance
- Trial name
- BEST (NCT03169309)
- Testing
- Brain Entrainment Technology
- Where
- Germany
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Landstuhl Regional Medical Center
HIV, AIDS
Lower Extremity Splinting to Manage Pain and Sleep Disturbances Associated With HIV/AIDS Related Peripheral Neuropathy
WHAT IS THE PURPOSE OF THIS STUDY? The investigators want to know if wearing a pair of splints at night works to bring the pain down and help you sleep better (in people living with HIV/AIDS related neuropathy).
- Conditions
- HIV, AIDS, Peripheral Neuropathy, Pain
- Trial name
- NCT01419314
- Testing
- Splinting application to the lower extremities, Splint liner application
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Texas Woman's University
Post Traumatic Stress Disorder, Depression
Treatment of Sleep Disturbances in Trauma-affected Refugees
The overall aim of this study is to examine the effects of sleep enhancing treatment in refugees with PTSD.
- Trial name
- PTF5 (NCT02761161)
- Testing
- Mianserin, Imagery Rehearsal Therapy
- Where
- Denmark
- Volunteers
- 241 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Parkinsons Disease
First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)
This study is researching an experimental drug called ALN-SNCA (called "study drug"). The study is focused on people with early Parkinson's disease, a disorder of the nervous system that affects movement.
- Trial name
- NCT07216066
- Testing
- ALN-SNCA
- Where
- 3 sites in Canada, Netherlands
- Volunteers
- 46 people
- Sponsor
- Regeneron Pharmaceuticals
Menopause Related Conditions
The Effects of Lateralized Thermal Sleepwear on Sleep, Skin Temperature and Skin Moisture in Menopausal Women
A home-based, sham-controlled, double-blind, crossover study evaluating the effects of wearing sleepwear with lateralized thermal characteristics on subjective and objective sleep measures, proximal skin temperature, and sternal…
- Trial name
- NCT03037554
- Testing
- Sleepwear with Lateralized Thermal Characteristics
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- St. Peter's Hospital, Albany, NY
Seasonal Allergic Rhinitis
Mometasone Furoate on Sleep Disturbances in Subjects With Seasonal Allergic Rhinitis (Study P04608) (COMPLETED)
This study will hope to show that by relieving the participant's nasal symptoms of seasonal allergies using mometasone furoate nasal spray, the participant will obtain a better quality of night-time sleep, which in turn, causes…
- Trial name
- NCT00358527
- Testing
- Mometasone Furoate Nasal Spray (MFNS)
- Volunteers
- 401 people
- Sponsor
- Organon and Co
Insomnia (moderate)
Impact of GABA Probiotic Lactiplantibacillus Plantarum Lp815 on Sleep Outcomes in Participants with Self-Reported Sleep Disturbance
The rationale for this study is to observe differences in sleep outcomes between a consumer-grade probiotic capsule called GABA Probiotic and a placebo control group.
- Trial name
- NCT06789718
- Testing
- GABA Probiotic Lactiplantibacillus plantarum Lp815 (5 Billion cfu/dose), Optional Sub-Study: Neurotransmitter Urine Test
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Verb Biotics LLC
Screen Time
Parental Education and Children's Screen Time
The study was to investigate the efficacy of a parental educational program on reducing screen use, and improving sleep quality and psychosocial adaptations in children aged 4-6 years.
- Trial name
- NCT04097587
- Testing
- experimental group, control group
- Where
- Taiwan
- Volunteers
- 129 people
- Sponsor
- Taipei Medical University
Child Behavior Problem
Hair Cortisol and Symptoms in Children With Psychopathology During CBT
This study aims to examine the relationship between hair cortisol concentration and behavior and sleep disturbance symptoms in children with psychiatric disorders.
- Trial name
- NCT06274424
- Testing
- The Friends Program
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Muscle Atrophy, Weightlessness
The Effects of Whole Body Unloading on Physiological Function
This study is a collaboration between the Centre of Human \& Aerospace Physiological Sciences (CHAPS) and the Sleep and Brain Plasticity Centre (Department of Neuroimaging) at King's College London and the Sleep Disorders Centre…
- Conditions
- Muscle Atrophy, Weightlessness, Sleep Disturbance, Astronaut-Bone Demineralisation Syndrome
- Trial name
- NCT03195348
- Testing
- HBF Bed Rest
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- King's College London
Stress Disorder, Post-Traumatic
Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance
The purpose of this study is to determine whether prazosin will reduce the incidence of nightmares, sleep disturbance, and overall symptoms in combat trauma-exposed individuals with PTSD.
- Trial name
- NCT00108420
- Testing
- Prazosin
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Pain, Sleep Disturbance
Radicle ACES: A Study of Commercially Available CBD Used in the Real-world Setting
A randomized, open-label study of commercially available, orally ingestible, Cannabidiol (CBD) products used in the real-world setting for pain, sleep, and anxiety.
- Conditions
- Pain, Sleep Disturbance, Anxiety
- Trial name
- RWE-ACES (NCT05003882)
- Testing
- Commercially available, orally ingestible CBD product
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Sleep Disturbances, Postoperative Discomfort
Effect of Virtual Reality and Binaural Beat on Sleep and Comfort in Adults After Mechanical Valve Replacement Surgery
This study will compare the effects of Virtual Reality and Binaural Beat Stimulation on sleep quality and discomfort in adult patients who have undergone prosthetic mechanical valve replacement surgery.
- Conditions
- Sleep Disturbances, Postoperative Discomfort, Heart Valve Diseases
- Trial name
- VR-BBS (NCT07365488)
- Testing
- Virtual Reality Relaxation, Binaural Beat Stimulation, VR + Binaural Beat Group
- Where
- Iraq
- Volunteers
- 140 people
- Sponsor
- University of Baghdad
Postoperative Sleep Disturbance
Perioperative EEG Prediction of Postoperative Sleep Disturbance in Gynecologic Laparoscopic Surgery
Postoperative sleep disturbance is common in patients undergoing gynecologic surgery and may affect postoperative recovery. This prospective observational cohort study will evaluate perioperative EEG changes in patients…
- Trial name
- NCT07857174
- Testing
- Perioperative Electroencephalographic Monitoring
- Where
- China
- Volunteers
- 300 people
- Sponsor
- General Hospital of Ningxia Medical University
Shift-Work Related Sleep Disturbance
Shift Work Intervention Strategies for Night Shift Workers
The goal of this intervention study is to test behavioral interventions in night shift workers. The main question it aims to answer is: Can personalized sleep or nutrition intervention strategies help against the negative health…
- Trial name
- GRIP (NCT06147089)
- Testing
- Sleep Intervention, Nutritional intervention
- Where
- Netherlands
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Autism Spectrum Disorders
Examining the Efficacy of Mattress Technology in Improving the Sleep Quality of Children With ASD
The purpose of the present study is to evaluate the tolerability and efficacy of the Sound To Sleep System™ in improving the sleep quality of children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02739321
- Testing
- Sound to Sleep System
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Sleep Disturbance
Intervention Study in Elderly With Sleep Problems
The main objective of the study is to improve subjective sleep quality using a multimodal intervention with an intervention and a control group. The multimodal intervention aims to improve circadian Zeitgeber strength.
- Trial name
- CIEL (NCT05485415)
- Testing
- Multimodal intervention, Control
- Where
- Switzerland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Mirjam Münch