Clinical trials: Disturbed Sleep
Sleep Disturbance
Prevention of Insomnia Using a Stepped Care Model in Adults
Insomnia is one of the most common sleep disorders and affects approximately 10 - 40% of the population across different age groups in Hong Kong.
- Trial name
- NCT06156293
- Testing
- Cognitive behavioral prevention program for insomnia (CBP-I)
- Where
- China
- Volunteers
- 1,016 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Sleep Disturbance
Effect of a Nurse-Led Environmental Stressor Reduction Package on Perceived Stress and Sleep Quality in Intensive Care Unit Patients
This study aims to evaluate the effect of a nurse-led Environmental Stressor Reduction Package on perceived environmental stress and sleep quality among adult patients in the intensive care unit (ICU).
- Trial name
- ICU-SLEEP (NCT07309406)
- Testing
- Environmental Stressor Reduction Package
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Fenerbahce University
Rectal Cancer, Low Anterior Resection Syndrome
Impact of Quality of Life in the Patients With Sleep Disturbance From Low Anterior Resection Syndrome in Advanced Rectal Cancer Patients
The preservation surgery of the anal sphincter has become a standard procedure for the treatment of rectal cancer and is now possible even when the tumor is close to the anus, thanks to the advancement of surgical techniques.
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, Insomnia
- Trial name
- NCT06271629
- Testing
- Insomnia severity index
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Glaucoma, Sleep Disturbance
Effects of Melatonin Supplementation on Sleep Quality in Patients With Advanced Glaucoma
A prospective, randomized, parallel, crossover, double-blind therapeutic clinical trial was conducted in accordance with the principles of the Resolution nº 466/12 of the National Health Council and was approved by the Ethics and…
- Conditions
- Glaucoma, Sleep Disturbance, Circadian Rhythm, Melatonin
- Trial name
- NCT06868745
- Testing
- Experimental: melatonin treatment group
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- University of Sao Paulo
Tinnitus, Sleep Disturbances
Low-intensity TUS for Sleep Disturbances in Patients With Chronic Tinnitus
Background: Tinnitus, as a common symptom, can jeopardize the sleep quality and brain function and even lead to hearing loss and cognitive decline in elderly patients.
- Conditions
- Tinnitus, Sleep Disturbances, Cognition
- Trial name
- NCT06776705
- Testing
- Low-intensity transcranial ultrasound stimulation
- Where
- 2 sites in Hong Kong
- Volunteers
- 14 people
- Sponsor
- Chinese University of Hong Kong
Sleep Disturbance, Aging
Chronic Moderate Sleep Restriction in Older Adults
Higher rates of mortality have been found both in short sleepers (< 6 hr/night) and long sleepers (> 8 hr/night), but there has been little experimental investigation of the effects of chronic, moderate sleep loss in long or…
- Trial name
- MSSS (NCT01642719)
- Testing
- Sleep restriction, Non-sleep restriction
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chronic Low Back Pain
Pilates and Resistance Training for Pain, Disability, and Sleep in Chronic Low Back Pain
This study will investigate the effect of Pilates and resistance training on pain, disability, and sleep quality in patients with chronic low back pain and sleep disturbances.
- Trial name
- NCT07291934
- Testing
- Combined Intervention (Pilates + Resistance Training), Pilates, Control (Usual Care)
- Where
- Palestinian Territories
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Atopic Dermatitis
The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance.
The purpose of the study is to evaluate the effect of ruxolitinib cream on sleep disturbances with participants with Atopic Dermatitis.
- Trial name
- MORPHEUS (NCT05696392)
- Testing
- ruxolitinib cream
- Where
- 30 sites in United States
- Volunteers
- 47 people
- Sponsor
- Incyte Corporation
Social Jet Lag, Sleep Disturbance
Self-Acupressure and Social Jet Lag in Female Health Sciences Students
This randomized, sham-controlled trial aims to evaluate the effects of self-administered acupressure on social jet lag, sleep patterns, and sleep quality in female health sciences students.
- Conditions
- Social Jet Lag, Sleep Disturbance, Sleep Quality, Circadian Rhythm Disruption
- Trial name
- NCT07410936
- Testing
- Self-Acupressure Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Sleep Disturbance
Esketamine Combined With Remimazolam on Postoperative Sleep Disturbance and Anxiety in Patients
To explore the effects of esketamine combined with remimazolam on postoperative sleep disturbance and anxiety in surgical patients undergoing gastroenteroscopies
- Trial name
- NCT06108830
- Testing
- Esketamine, Remimazolam, Esketamine and remimazolam
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Tianjin Medical University General Hospital
Sleep Disturbance, Sleep Patterns
Probiotics on Sleep Among Adults Study
The aim of this study is to determine the impact of a probiotic formulation on subjective sleep patterns. It is hypothesized that participants given the probiotics will improve their sleep patterns compared to participants…
- Trial name
- NCT04767997
- Testing
- Probiotic formulation
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Parkinson's Disease
Study for Rasagiline Effect on Sleep Trial(REST)in Parkinson's Disease
The main objective of this study is to evaluate the effect of Azilect® on sleep disturbances in Parkinson's Disease patients, after 2 months of treatment.
- Trial name
- PD (NCT01032486)
- Testing
- Rasagiline mesylate
- Volunteers
- 120 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Depression, Postpartum Depression
Personalized Integrated Chronotherapy for Perinatal Depression
Perinatal depression and anxiety are common, serious, and frequently overlapping disorders that increase morbidity and mortality in new mothers (including suicide) and result in poor infant/child outcomes.
- Conditions
- Depression, Postpartum Depression, Prenatal Disorder, Circadian Dysregulation
- Trial name
- NCT04364646
- Testing
- Personalized Integrated Chronotherapy
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Rhode Island Hospital
Sleep Initiation and Maintenance Disorders, Sleep
Sleep Disturbances in the 2nd and 3rd Trimester
Sleep disorders and disturbances are mostly underestimated in clinical practice. Moreover, this problem is generally neglected by the pregnant themselves.
- Conditions
- Sleep Initiation and Maintenance Disorders, Sleep, Sleep Apnea, Sleep Disorder
- Trial name
- NCT03763071
- Testing
- Patient-reported scales to measure sleep disorders
- Where
- Turkey (Türkiye)
- Volunteers
- 683 people, healthy volunteers welcome
- Sponsor
- Bartin State Hospital
Fatigue, Sleep Disturbances
A Yoga Program for Breast Cancer Patients Undergoing Chemotherapy
The primary aim of this study is to assess and compare change in QOL during chemotherapy as measured by the Functional Assessment of Cancer Therapy-Breast (FACT-Breast) score between patients receiving yoga and those not…
- Trial name
- NCT02360904
- Testing
- Yoga
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Sleep Disturbance, Heart Failure
Improving Sleep Quality in Heart Failure
Poor sleep quality is common in patients with heart failure. The limited available evidence intimates that improving sleep quality in patients with heart failure may improve morbidity and quality of life in this patient…
- Trial name
- NCT03307005
- Testing
- Zolpidem Tartrate
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Sleep Disturbance, Obesity, Severe
6th Month EWL% After Sleeve Gastrectomy to Get a Better Sleep Quality
Obesity, caused by caloric intake over output, has become a global health problem. The relationship between sleep and obesity is widely discussed in the literature.
- Conditions
- Sleep Disturbance, Obesity, Severe, Surgery
- Trial name
- NCT05608031
- Testing
- Pittsburgh sleep quality index (PSQI) scale
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Umraniye Education and Research Hospital
Dementia
Circadian Rhythm and Other Factors in Memory Clinic Patients
The CIRCAME study is a bicentric study of patients from 2 memory clinics in Paris. The main objective is to identify circadian rhythm components and other individual risk factors (sociodemographic, behavioral, and health related…
- Trial name
- CIRCAME (NCT05977712)
- Testing
- Questionnaire, Clinical examination, Accelerometer port
- Where
- 2 sites in France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Physical Therapy, Resistance Exercise
Resistance Exercise and Sleep Quality by Chronotype
This study examines whether doing moderate resistance exercises in the morning can improve sleep quality and well-being in young adults.
- Conditions
- Physical Therapy, Resistance Exercise, Sleep Disturbances, Sleep Quality
- Trial name
- TRE-SLEEP (NCT07234812)
- Testing
- Moderate-Intensity Resistance Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Medipol University
Chronic Pain, Musculoskeletal Pain
Weighted Blanket Use for Adults With Chronic Pain
Chronic pain is a common condition that can affect sleep, daily functioning, and overall quality of life. Many individuals living with chronic pain seek non-medication approaches to help manage their symptoms.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Sleep Disturbance, Pain Disorders
- Trial name
- EMBRACE (NCT07498491)
- Testing
- Weighted Blanket
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National University of Natural Medicine