Clinical trials: Disturbed Sleep
Restless Legs Syndrome
Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And Associated Sleep Disturbance
The purpose of this study is to assess the efficacy and safety of pregabalin and pramipexole versus placebo in the treatment of restless legs syndrome and associated sleep disturbance.
- Trial name
- NCT00991276
- Testing
- pregabalin, pramipexole
- Where
- 41 sites in United States
- Volunteers
- 85 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Childhood Cancer Survivors
Pain and Sleep Disturbances in Children Living Beyond Cancer: A Case-Control Study
Children living beyond cancer (CBC) represent a unique and growing population of young people in need of long-term clinical support.
- Trial name
- NCT07120646
- Testing
- Questionnaire, actigraphy measurement and sleep diary
- Where
- 2 sites in Belgium
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Post-traumatic Stress Disorder
Assessment of Sleep Disturbance as a Biomarker of Disease Activity in a Military Population With Posttraumatic Stress Disorder
Post-Traumatic Stress Disorder (PTSD) is a public health problem due to both its chronic nature and the low response rate to conventional therapies.
- Trial name
- SOMMEPT (NCT04581850)
- Testing
- Sleep recording, Cognitive tasks, Questionnaires
- Where
- 6 sites in France
- Volunteers
- 190 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Sleep Disturbance
Comparison Between the Effect of Two Different Doses of Oral Melatonin on Sleep Quality After Total Hip Arthroplasty
Considering the fact that melatonin was safely and effectively used in higher doses in multiple surgical conditions , the present study hypothesized that increasing melatonin dose in THA would have better benefits for patients.
- Trial name
- NCT07732725
- Testing
- Melatonin 5 MG, Melatonin 10 MG
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Benha University
Atopic Dermatitis
Comprehensive Investigation of Opiates, Neuropeptides, Barrier Function, Scratching and Sleep Physiology
The purpose of this research is to study the sleep patterns of people with moderate to severe atopic dermatitis and how itching affects those patterns.
- Trial name
- NCT00696397
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Sleep Disturbance
Sleep Disturbance in Chronic Rhinitis
The aim of this study is to evaluate the characteristic of sleep disturbance in allergic and non-allergic rhinitis in Dr. Cipto Mangunkusumo Hospital, Jakarta.
- Trial name
- NCT05312723
- Where
- Indonesia
- Volunteers
- 22 people
- Sponsor
- Universitas Indonesia
Sleep Disturbance, Aging
Hong Kong Cohort of Abnormal Sleep in Ageing Population (HK-ASAP): Focusing on Brain Health and Sleep Quality
Poor sleep quality can significantly jeopardize the brain health, cognitive functions, daily activities, quality of life, and even be implicated as a key potential contributing factor in the development of accelerated cognitive…
- Conditions
- Sleep Disturbance, Aging, Cognitive Decline, Brain Disease
- Trial name
- HK-ASAP (NCT06170073)
- Where
- Hong Kong
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Cancer (Diagnosis), Anxiety
Virtual vs Physical Art Therapy for Anxiety, Psychological Well-being, and Sleep Quality in Colorectal Cancer Patients
This randomized controlled trial aims to evaluate the effects of virtual reality-based art therapy and physical art therapy on anxiety, psychological well-being, and sleep quality in patients with colorectal cancer receiving…
- Conditions
- Colorectal Cancer (Diagnosis), Anxiety, Sleep Disturbance
- Trial name
- PVART-CRC (NCT07464626)
- Testing
- Virtual Reality Art Therapy, Physical Art Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Dokuz Eylul University
AMCI - Amnestic Mild Cognitive Impairment, Sleep Disturbance
Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone
To investigate the effect of trazodone on sleep, hippocampal-dependent memory and hippocampal excitability. The investigators hypothesize that trazodone will improve total sleep time and proportion of time in Slow Wave Sleep…
- Trial name
- REST (NCT05282550)
- Testing
- Trazodone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Sleep Disturbance, Psychotic Disorders
Sleep Disturbances in Patients With Psychotic Symptoms (AkuSleep)
Sleep disturbance is recognized as a major problem for patients with psychosis and is seen in nearly all patients admitted in acute crisis to a psychiatric hospital.
- Trial name
- AkuSleep (NCT04290650)
- Testing
- Modified CBT for insomnia, Treatment as usual
- Where
- Norway
- Volunteers
- 75 people
- Sponsor
- Oslo University Hospital
Sleep Disturbances
Individually Tailored Lighting System to Improve Sleep in Older Adults
In conjunction with investigators at the Cecil G. Sheps Center for Health Services Research, University of North Carolina (UNC) at Chapel Hill, we propose to develop and evaluate a low-cost, minimally obtrusive device that…
- Trial name
- NCT01855126
- Testing
- Blue light, Red light
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Rensselaer Polytechnic Institute
Stroke, Cardiovascular Diseases
Music for Sleep After Stroke
Sleep difficulties are common following stroke yet effective evidence-based interventions for improving sleep in this population are lacking.
- Conditions
- Stroke, Cardiovascular Diseases, Brain Diseases, Vascular Diseases
- Trial name
- MUSAS (NCT05867290)
- Testing
- Mindful music-listening with sleep hygiene
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- NHS Greater Glasgow and Clyde
Cancer, Sleep Disturbance
Yoga During Chemotherapy Study
This proposal aims to expand non-pharmacologic options for the control of symptoms during chemotherapy using yoga practices. It is particularly focused on sleep disturbance with a secondary focus on fatigue.
- Conditions
- Cancer, Sleep Disturbance, Fatigue
- Trial name
- NCT02442635
- Testing
- Yoga
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of California, San Francisco
Neoplasm, Sleep Disturbance
Dream2Heal: An Adaptive Stepped-care Intervention for Chinese Cancer Survivors With Mild-to-moderate Insomnia
The primary objective of this feasibility study is to assess the feasibility and acceptability, and potential clinical significance of an adaptive stepped-care intervention for improving sleep quality among Chinese cancer…
- Trial name
- NCT06813235
- Testing
- iDream2Heal, Easy Exercise, Dream2Heal
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder
Usefulness of NESA Microcurrents in the Treatment of Children With Autism Spectrum Disorders
The term or definition of Autism Spectrum Disorder (ASD) defines a pervasive neurodevelopmental disorder in which deficits in communication and social interaction, altered sensorimotor behaviours, repetitive, restricted and…
- Trial name
- NCT06417450
- Testing
- Non-invasive Neuromodulation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Las Palmas de Gran Canaria
Violent Suicide Attempts in Adolescents
Mentalization and Social Cognition in Adolescents After Suicide Attempt
This study investigates the risk of violent suicide attempts in adolescents, with a particular focus on social cognition and sleep disturbances, to better understand the cognitive and behavioral mechanisms involved and to inform…
- Trial name
- MENTACOG-TS (NCT07688798)
- Testing
- Test, Questionnaires
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep Disturbance, Sleep Disorder
Improving Sleep in BMT Survivors
The purpose of this study is to: To test a new intervention for sleep disturbance among hematopoietic cell transplant survivors. About 60 hematopoietic cell transplant (HCT) survivors will participate in this intervention.
- Trial name
- NCT03537963
- Testing
- mHealth Stepped-care Intervention, Educational Control Condition, Questionnaire
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Attention Deficit Hyperactivity Disorder, Sleep Disturbance
Settling Down for Sleep in ADHD: The Impact of Sensory and Arousal Systems on Sleep in ADHD
The goal of this study is test the hypothesis that sleep problems for children with ADHD are linked to sensory over-responsivity, a type of sensory processing difference that causes a person to interpret daily sensory input as…
- Trial name
- NCT06406309
- Testing
- Power Down manipulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Hepatic Encephalopathy, Liver Cirrhosis
The Effect of Induced Hyperammonaemia on Sleep and Melanopsin-mediated Pupillary Light Response in Patients With Liver Cirrhosis
Sleep disturbances are common among patients with liver cirrhosis, but the reasons are not well understood. In this project the investigators evaluated whether an increase in blood ammonia in patients with cirrhosis had an impact…
- Conditions
- Hepatic Encephalopathy, Liver Cirrhosis, Sleep Disturbance
- Trial name
- NCT04771104
- Testing
- Amino Acid Challenge (AAC)
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postural Tachycardia Syndrome, Chronic Orthostatic Intolerance
Objective Sleep Disturbances in Orthostatic Intolerance
We wish to study sleep architecture in patients with chronic orthostatic intolerance. We will test the null hypothesis that there is no difference in time during the various phases of sleep between patients and healthy control…
- Trial name
- NCT00581022
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Satish R. Raj