Clinical trials: Disturbed Sleep
Sleep Disturbance, Circadian Rhythm Sleep Disorders
Effect of an Eye Mask-Based Blackout Protocol on Sleep Quality and Melatonin
Sleep disturbance is a common problem among patients hospitalized in intensive care units due to continuous light exposure, noise, and frequent medical interventions.
- Conditions
- Sleep Disturbance, Circadian Rhythm Sleep Disorders, Intensive Care Unit Patients
- Trial name
- NCT07385768
- Testing
- Eye Mask-Based Blackout Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Sleep Disturbance, Fatigue
The Effects Of Kiwifruit Consumption On Sleep Quality, Fatigue And BMI Of Saudi Adults
Hypothesis: Kiwifruit contains antioxidants and serotonin which may be beneficial in the treatment of sleep disruption. Aim: to assess the effects of daily intake of kiwifruit on sleep quality, fatigue, and BMI among Saudi adults…
- Conditions
- Sleep Disturbance, Fatigue, Body Weight
- Trial name
- NCT05953324
- Testing
- Kiwifruit
- Where
- Saudi Arabia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Chronic Pain, Chiari Malformation
Examining Different Components of Online Acceptance and Commitment Therapy for People With Chiari Malformation
Chiari Malformation (CM) is a chronic health condition characterized by brain and spinal malformations and displacements that cause obstruction of cerebrospinal fluid (CSF; Hadley, 2002) circulation.
- Trial name
- NCT05581472
- Testing
- Online Acceptance and Commitment Therapy Intervention + Phone Coaching, Online Acceptance and Commitment Therapy Intervention without phone coaching
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Kent State University
Esketamine, Sleep Disturbance
Esketamine on Postoperative Sleep Disturbance of Patients Undergoing Spinal Surgery
The goal of this clinical trial is to learn about the effect of intraoperative esketamine infusion on postoperative sleep disturbance(PSD) of patients undergoing spinal surgery.
- Conditions
- Esketamine, Sleep Disturbance, Spinal Surgery
- Trial name
- NCT06451627
- Testing
- Esketamine, saline
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Gastroesophageal Reflux Disease (GERD)
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disease (GERD)
This study includes patients with sleep disturbances associated with gastroesophageal reflux disease (GERD) and has 3 treatment arms.
- Trial name
- NCT00628342
- Testing
- Esomeprazole
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Acquired Brain Injury
Weighted Blankets After Brain Injury
A non-blinded randomised controlled feasibility study of weighted blankets to help agitation and disturbed sleep after brain injury. This is a single centre study based in a community hospital in the UK.
- Trial name
- WEBLY (NCT04860973)
- Testing
- Weighted blankets
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Anxiety, Pain
Evaluation of a Self-Care Toolkit in Surgical Breast Cancer Patients
This randomized controlled trial (RCT) in newly-diagnosed breast cancer patients seeks to determine the effectiveness of a self-care toolkit on specific symptoms associated with surgery as compared to a standard care group.
- Conditions
- Anxiety, Pain, Nausea, Fatigue
- Trial name
- NCT02387320
- Testing
- Self-Care Toolkit
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Samueli Institute for Information Biology
Heart Rate, Sleep Habit
EaseAlert: Tactile Firefighter Alerting System
The purpose of this research is to test a commercially viable Fire Fighter Altering System (FFAS) comprised of proprietary wearables and optional bed shakers called BunkAlerts; collectively "personal alerting devices" as an…
- Conditions
- Heart Rate, Sleep Habit, Sleep
- Trial name
- NCT05641194
- Testing
- Legacy Alerting System, Intervention 2: EaseAlert Standalone
- Where
- 2 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Embry-Riddle Aeronautical University
Insomnia, Depression
Cognitive-Behavioral Therapy for Sleep Disturbance in Patients Undergoing Hemodialysis
Background More than 50% of dialysis patients experience sleep disturbances that significantly affect quality of life, overall morbidity, and mortality.
- Conditions
- Insomnia, Depression, Inflammation
- Trial name
- NCT01159197
- Testing
- cognitive behavioral therapy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Far Eastern Memorial Hospital
Advanced Parkinson's Disease
A Study to Assess Change in Sleep Disturbances of Adult Participants With Advanced Parkinson's Disease Receiving Subcutaneous Foslevodopa/Foscarbidopa
Parkinson's disease (PD) is a neurological condition, which affects the brain. Some symptoms of PD are tremors, stiffness, and slowness of movement.
- Trial name
- ONIROS (NCT07284342)
- Where
- 16 sites in Spain
- Volunteers
- 103 people
- Sponsor
- AbbVie
Neurobehavioral Manifestations, Drug Related Sleep Disturbance
Acute and Residual Effects of Caffeinated Beer
The aim of this study is to develop information about the acute and residual effects of a new product being targeted to young adults.
- Conditions
- Neurobehavioral Manifestations, Drug Related Sleep Disturbance, Alcohol Intoxication
- Trial name
- NCT00515294
- Testing
- Caffeinated Alcoholic Beer, Non-Caffeinated Alcoholic Beer, Caffeinated Non-Alcoholic Beer
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Boston University
Sleep Disturbance
A Study to Evaluate the Effects of the Speed Sleep Supplement on Sleep Quality and Quantity
This study evaluates the effects of the Speed Sleep supplement on sleep quality and quantity in adults aged 18-65 years. Participants will be randomized to receive either the supplement or placebo for 4 weeks, with outcomes…
- Trial name
- NCT07564817
- Testing
- Dietary Supplement: Speed Sleep
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bio Nature Health
Sleep Initiation and Maintenance Disorders, Osteoarthritis
Sleep in Osteoarthritis Project
Osteoarthritis (OA) is one of the most common diseases and one of the leading causes of disability in the world. People with OA frequently experience sleep disturbances, primarily due to pain.
- Trial name
- SOAP (NCT00592449)
- Testing
- Cognitive behavioral therapy (CBT) for insomnia, Behavioral desensitization treatment for insomnia
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
AMCI - Amnestic Mild Cognitive Impairment, Sleep Disturbance
Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone
To investigate the effect of trazodone on sleep, hippocampal-dependent memory and hippocampal excitability. The investigators hypothesize that trazodone will improve total sleep time and proportion of time in Slow Wave Sleep…
- Trial name
- REST (NCT05282550)
- Testing
- Trazodone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Sleep Disturbance
Citrus Extract, Sleep and Mental Wellbeing
This is a randomized, double-blind, placebo-controlled, cross-over trial investigating the effects of daily administration of citrus extract on sleep and mental wellbeing.
- Trial name
- NCT06239168
- Testing
- Citrus extract, Maltodextrin
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sleep Disturbance
The SLEEP-CARE Study
Sleep disorder is common in ICU patients, such as reduced sleep time, fragmentation, and abnormal sleep rhythm. In 2023, American Thoracic Society released a research statement on sleep and circadian disruption(SCD) in ICU, which…
- Trial name
- NCT06336408
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Zhongshan Hospital
Sleep Disturbance
Sleep Quality During COVID-19 Containment in Children Whether or Not Usually Followed in Child Psychiatry
The purpose of this study is to determine whether sleep disturbances in children aged 7 to 12 during COVID-19 containment are more prevalent in children who received routine psychiatric care before containment compared to…
- Trial name
- CONFIDODO (NCT04370210)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Hôpital NOVO
Alzheimer's Disease
Effects of Light-therapy in Alzheimer's Disease
Background: Management of patients with Alzheimer's disease associated with behavioral disturbances is difficult especially in those with agitation/aggression and insomnia and nighttime behaviors.
- Trial name
- ALZ-Light (NCT02686190)
- Testing
- Luxtherapy
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep Disturbance, Stress
GUT-FEELINGS: Using Citizen Science for Large-Scale Prebiotic Clinical Trials for Mental Wellness in Adults
The goal of this study is to evaluate the effects of different products in participants experiencing feelings of anxiety. The main question it aims to answer is: Do these products affect feelings of anxiety and related wellness…
- Conditions
- Sleep Disturbance, Stress, Feeling Anxious
- Trial name
- NCT07752823
- Testing
- Active Gut Feeling Product 1, Active Gut Feeling Product 2
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Holobiome, Inc.
Insomnia, Sleep Disturbance
Sleeping For Two: Trial for CBT for Insomnia in Pregnancy
Cognitive-behavioural therapy for insomnia (CBT-I) has been shown to be an effective treatment for insomnia in multiple populations, including women during pregnancy and postpartum.
- Trial name
- NCT03918057
- Testing
- Cognitive Behavioural Therapy for Insomnia, Active Control
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- University of Calgary