Clinical trials: Disturbed Sleep
Menopause, Sleep Disturbance
Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes
A randomized, double-blind, placebo-controlled, direct-to-consumer trial assessing the impact of health and wellness products on hormonal health and associated health outcomes in women with menopausal health issues
- Conditions
- Menopause, Sleep Disturbance, Anxiety, Depression
- Trial name
- NCT06749288
- Testing
- Radicle Revive Active Study Product 4.1 Usage
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Postoperative Delirium (POD), Postoperative Sleep Disturbance
Effects of Esketamine on the Incidence of Postoperative Delirium and Postoperative Sleep Disturbance in Elderly Patients After Major Non-cardiac Surgery
Postoperative delirium (POD) is a common surgical complication.It is associated with a range of negative outcomes such as delayed postoperative recovery,prolonged hospitalization,additional medical expenditures and higher…
- Trial name
- EPISODE (NCT06900205)
- Testing
- Esketamine, 0.9 % saline
- Where
- China
- Sponsor
- RenJi Hospital
Caffeine Dependence, Anxiety
Remote Guided Caffeine Reduction
The purpose of this online research study is to determine whether or not a gradual caffeine reduction program developed at Johns Hopkins can help people reduce their caffeine use.
- Conditions
- Caffeine Dependence, Anxiety, Sleep Disturbance, Gastrointestinal Dysfunction
- Trial name
- NCT04560595
- Testing
- Caffeine Reduction Manual
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sleep Disturbance, Sleep Deprivation
Implementing Behavioral Sleep Intervention in Urban Primary Care
Investigators will enroll up to 20 participants from 3 Children's Hospital of Philadelphia (CHOP) primary care locations. The primary objective is to determine the whether the Sleep Well! behavioral sleep intervention is feasible…
- Conditions
- Sleep Disturbance, Sleep Deprivation, Sleep
- Trial name
- Aim_2 (NCT04046341)
- Testing
- Sleep Well!
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital of Philadelphia
Postural Tachycardia Syndrome, Chronic Orthostatic Intolerance
Objective Sleep Disturbances in Orthostatic Intolerance
We wish to study sleep architecture in patients with chronic orthostatic intolerance. We will test the null hypothesis that there is no difference in time during the various phases of sleep between patients and healthy control…
- Trial name
- NCT00581022
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Satish R. Raj
Parkinson's Disease
Effect of Melatonin on Sleep Disturbances in Patients With Parkinson's Disease
This clinical study is a double-blind, randomized, placebo-controlled trial to investigate the effects of melatonin on the sleep disturbance symptoms of Parkinson's disease patients, symptoms which have a significant impact on…
- Trial name
- NCT03258294
- Testing
- Melatonin(Circadin®)
- Volunteers
- 82 people
- Sponsor
- KIMJisun
Brain Cancer
Fatigue, Sleep and Cytokines in Primary Brain Tumor (PBT) Patients
This goal of this research study is to learn more about fatigue, sleep quality, and other symptoms in patients with primary brain tumors who are being treated with radiation therapy. Objectives: PRIMARY OBJECTIVE: 1.
- Trial name
- NCT00876499
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Thermoregulation, Sleep Disturbance
Acute Sleep Deprivation on Whole-body Heat Exchange During Exercise-heat Stress in Young and Older Men
Sleep deprivation has long been thought to modulate thermoregulatory function. Seminal work on sleep deprivation and thermoregulation has demonstrated that sleep-deprived individuals experience greater elevations in core…
- Conditions
- Thermoregulation, Sleep Disturbance, Heat Exchange, Aging
- Trial name
- NCT05838014
- Testing
- Sleep deprivation, Normal sleep
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Advanced Cancers
The Use of Light Therapy for Managing Sleep Disturbances in Patients With Advanced Cancer
The goal of this research study is to learn if a type of light therapy can be used to help patients with advanced cancer who are having difficulty sleeping to sleep better.
- Trial name
- NCT01193530
- Testing
- Bright Light Therapy, Dim Red Light Therapy, Questionnaires
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- M.D. Anderson Cancer Center
Sleep Disturbance
Kneipp Water Applications for Insomnia
The purpose of this study is to ascertain whether warm footbathes are effective on sleep disturbances in women before climacteric.
- Trial name
- KWAI (NCT03114189)
- Testing
- footbath, care of sleep
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universität Duisburg-Essen
Sleep, Sleep Disturbance
Radicle Rest 2: A Study of Health and Wellness Products on Sleep and Health Outcomes
A randomized, blinded, placebo-controlled direct-to-consumer study assessing the impact of health and wellness products on sleep and other health outcomes.
- Conditions
- Sleep, Sleep Disturbance, Sleep Disorder
- Trial name
- NCT05657808
- Testing
- Rest Study Active Product 1.1 Usage, Rest Study Active Product 1.2 Usage, Rest Study Active Product 2.1 Usage
- Where
- United States
- Volunteers
- 4,152 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Postoperative Sleep Disturbance
Perioperative EEG Prediction of Postoperative Sleep Disturbance in Gynecologic Laparoscopic Surgery
Postoperative sleep disturbance is common in patients undergoing gynecologic surgery and may affect postoperative recovery. This prospective observational cohort study will evaluate perioperative EEG changes in patients…
- Trial name
- NCT07857174
- Testing
- Perioperative Electroencephalographic Monitoring
- Where
- China
- Volunteers
- 300 people
- Sponsor
- General Hospital of Ningxia Medical University
Stress, Psychological, Sleep Disturbance
The Effect of a Combined Nature-based and Virtual Mindfulness Intervention on Perceived Stress in Healthcare Workers
Rationale: Healthcare workers that care for patients with COVID-19 are at increased risk for stress-related symptoms. When these symptoms are chronic, they can result in burnout and other mental health conditions that can…
- Conditions
- Stress, Psychological, Sleep Disturbance, Burnout, Caregiver, Posttraumatic Stress Disorder
- Trial name
- NCT04846790
- Testing
- Nature Only, Nature+Mindfulness
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Sleep, Sleep Inertia
Sensible Sleep: Measuring Alarm and Snooze Behavior in Teens Using Wearables and Smartphones
Pilot data suggests that working professionals and college students routinely use alarms and snooze. Alarm usage and snoozing is associated with several negative health biomarkers including lighter sleep, higher resting heart…
- Conditions
- Sleep, Sleep Inertia, Stress
- Trial name
- NCT04786678
- Testing
- Cell phone notification
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Notre Dame
Narcolepsy, Cataplexy
An Open Label Study of FT218 in Subjects With Narcolepsy
An Open Label Study to Evaluate Long-Term Safety and Tolerability of a Once Nightly Formulation of Sodium Oxybate for Extended-Release Oral Suspension (FT218) and the ability to switch from twice-nightly immediate release sodium…
- Conditions
- Narcolepsy, Cataplexy, Excessive Daytime Somnolence, Sleep Disorder
- Trial name
- RESTORE (NCT04451668)
- Testing
- FT218
- Where
- 29 sites in United States, Canada
- Volunteers
- 184 people
- Sponsor
- Avadel
Stress Disorders, Post-Traumatic, Combat Disorders
Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to determine whether prazosin will: reduce the incidence of nightmares and sleep disturbance increase functioning and sense of well being in combat-trauma exposed Operation Iraqi Freedom/Operation…
- Conditions
- Stress Disorders, Post-Traumatic, Combat Disorders, Sleep Disorders
- Trial name
- NCT00990106
- Testing
- prazosin hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Sleep
Effects of Napping in Pregnant Women With Sleep Disturbances on Offspring Neurodevelopment
To examine the effects of napping in pregnant women with sleep disturbances on offspring neurodevelopment, the researchers will recruit 80 pregnant women with sleep disturbances.
- Trial name
- NCT06514833
- Testing
- lifestyle recommendations to nap regularly, No recommendations to nap regularly
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Sleep Disorders in Children
Melatonin Adolescent Research Study
The present study will use a within-person, randomized cross-over experimental design to test the effects of exogenous melatonin supplementation on the sleep and daytime functioning of typically developing adolescents with short…
- Trial name
- MARS (NCT04588233)
- Testing
- Melatonin
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Loma Linda University
Endocrine Responsive Early Breast Cancer
Impact of Adjuvant Treatment With Aromatase Inhibitor on Sleep Disturbances in Postmenopausal Women With Endocrine Responsive Early Breast Cancer
Insomnia is common in Breast cancer patients during adjuvant therapy with aromatase inhibitor. However it is difficult to establish whether it is due to the knowledge of the disease or the treatment administred.
- Trial name
- NCT02166281
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Schizophrenia, Insomnia Related to Schizophrenia (307.42)
Sodium Oxybate in Schizophrenia With Insomnia
The present protocol proposes study of the recently approved compound sodium oxybate (Xyrem), a gamma-aminobutyric acid type b (GABAB) and a g-hydroxybutyric acid (GHB) receptor agonist, for the study of persistent symptoms of…
- Trial name
- NCT00594256
- Testing
- Sodium Oxybate
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research