Clinical trials: Disturbed Sleep
Insomnia, Insomnia Chronic
SHADES Mechanistic Trial
Cardiovascular disease (CVD) is common, deadly, and costly, and adults with insomnia represent a large group of people at elevated risk of developing CVD in the future.
- Conditions
- Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance
- Trial name
- SHADES (NCT06041581)
- Testing
- Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Sleep Disturbance
Feasibility of a Mobile App on Sleep
This study investigates the feasibility and effects of a mindfulness meditation mobile application on sleep for individuals reporting sleep disturbances.
- Trial name
- NCT04045275
- Testing
- Calm
- Where
- United States
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Sleep Disturbance
Blocking Blue Light in Pregnancy, Effects on Melatonin Profile and Sleep
Sleep disturbances are common in pregnancy, and the incidence increases during the third trimester. Light and specially the blue wavelengths of light, is affecting sleep and the circadian rhythm.
- Trial name
- NCT03114072
- Testing
- Blue-blocking glasses, Light grey control glasses
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Bergen
Sleep Disturbance
Perioperative Lignocaine and Sleep Disturbance
The aim of this clinical trial is to study the effect of an intravenous infusion of lidocaïne in a multimodal analgesic protocol on the architecture sleep during the first postoperative night.
- Trial name
- NCT03317912
- Testing
- Lidocaïne 2%
- Volunteers
- 40 people
- Sponsor
- University of Liege
Sleep Disturbance, Autism Spectrum Disorder
Community-Engaged Sleep Intervention for School-Aged Children With Autism Spectrum Disorder
As many as 78% of children with autism spectrum disorder (ASD) have significant sleep disturbance compared to 20% of children without ASD.
- Trial name
- NCT07007819
- Testing
- Modified Sleep and Circadian Intervention, Enhanced Usual Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Case Western Reserve University
Grief, Anxiety
Online Multi-component Psychological Intervention for Prevention of Grief Disorder Due to COVID-19
This study evaluates the effectiveness of an online Multi-component psychological intervention, that is focused on providing self-support to the Mexican population for the prevention of complicated grief disorder, by reducing…
- Conditions
- Grief, Anxiety, Depression, Sleep Disturbance
- Trial name
- NCT04638842
- Testing
- Online Intervention Grief COVID-19
- Where
- Mexico
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Sleep Apnea Syndrome
Stair Stepping Exercise Training in Patients With Obstructive Sleep Apnea Syndrome
This 3-year prospective, randomized, control, longitudinal study is aimed to (1) examine the effect of stair stepping exercise training on cardiopulmonary fitness and sleep situation in patients with Obstructive Sleep Apnea…
- Trial name
- NCT00952172
- Testing
- stair stepping exercise
- Volunteers
- 47 people
- Sponsor
- Chang Gung Memorial Hospital
Major Abdominal Surgery, Postoperative Delirium (POD)
MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES)
This study aims to determine whether, compared with placebo, the nighttime self-administration of a nasal dexmedetomidine is effective at inducing sleep and preventing postoperative delirium in high-risk patients.
- Conditions
- Major Abdominal Surgery, Postoperative Delirium (POD), Sleep Disturbances, Intranasal Dexmedetomidine
- Trial name
- MIDDIES (NCT07538284)
- Testing
- Dexmedetomidine
- Volunteers
- 400 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Sleep Disturbances in Survivors of Critical Illness
Johrei Therapy and CBT-I in Facilitating Sleep in ICU Survivors
The purpose of this project is to compare the effectiveness of Johrei therapy (JT) and Cognitive-behavioral Therapy for Insomnia (CBT-I) in the treatment of sleep disturbances in survivors of critical illness.
- Trial name
- NCT02059421
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Johrei therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Arizona
Mood Disturbance, Mood Change
Mood and Cognitive Effects of Psilocybin in Healthy Participants
This study is seeking to find the optimal microdose or low dose of psilocybin (magic mushrooms) that provides general enhancements to mood, memory, sleep, and other measures of general well-being without any hallucinogenic…
- Conditions
- Mood Disturbance, Mood Change, Sleep Disturbance, Drug Effect
- Trial name
- MELO (NCT05252598)
- Testing
- Psilocybin, Inonotus Obliquus Whole Extract
- Volunteers
- healthy volunteers welcome
- Sponsor
- Optimi Health Corporation
Stress Reaction, Sleep Disturbance
Functional Assessment of Ashwagandaha Root Extract During Weight Loss
Patients who are involved in a clinical protocol driven 12 week medical weight loss intervention will be randomized to receive either a placebo or 600 mg of an ashwagandha root extract.
- Conditions
- Stress Reaction, Sleep Disturbance, Craving, Obesity
- Trial name
- NCT03112824
- Testing
- Ashwagandha Root Extract Capsule
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Prostate Cancer, Sleep Disturbance
eMindExCare for Prostate Cancer Patients Undergoing Active Treatment
This feasibility randomized controlled trial will assess the acceptability, feasibility, and preliminary effects of an integrated mindfulness and exercise eHealth intervention, eMindExCare, among prostate cancer patients…
- Conditions
- Prostate Cancer, Sleep Disturbance, Fatigue, Physical Inactivity
- Trial name
- eMindExCare (NCT07735273)
- Testing
- eMindExCare, Enhanced Health Education
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Pain, Sleep Disturbance
Radicle ACES: A Study of Commercially Available CBD Used in the Real-world Setting
A randomized, open-label study of commercially available, orally ingestible, Cannabidiol (CBD) products used in the real-world setting for pain, sleep, and anxiety.
- Conditions
- Pain, Sleep Disturbance, Anxiety
- Trial name
- RWE-ACES (NCT05003882)
- Testing
- Commercially available, orally ingestible CBD product
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Sleep Disturbance
Reports on Sleep Quality and Thermoregulation Among Veterans
To assess and compare the quality of sleep self- reported by veterans with sleep disorders before and after use of the Chilipad cooling mattress pad
- Trial name
- ReSQuTheVets (NCT04236661)
- Testing
- chilipad
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Pregnancy Related, Sleep
Sleep in Late Pregnancy - Artificial Intelligence Development for the Detection of Disturbances and Disorders
SLeeP AID4 is a single-group, single-arm, Canada-wide, non-randomised, unblinded, in-home, observational study to prospectively collect and build a data set of natural sleep behaviour and physiology in maternal-fetal dyads (and…
- Conditions
- Pregnancy Related, Sleep, Sleep-Disordered Breathing, Sleep Disturbance
- Trial name
- SLeeP AID4 (NCT05376475)
- Testing
- Infrared video-audio camera, Level III home sleep apnea test, Maternal-fetal transabdominal electrocardiographic heart rate monitor
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Insomnia, Parkinson's Disease
Valerian to Improve Sleep in Patients With Parkinson's Disease
The purpose of this trial is to test the short-term effectiveness of valerian, a medicinal herb, to improve sleep in patients with Parkinson's disease (PD).
- Trial name
- NCT00070928
- Testing
- valerian
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Chronic Heart Failure, Obstructive Sleep Apnea
CPAP and Physiotherapy for Heart Failure and Sleep Apnea in the Elderly
This study evaluates whether adding physiotherapy (including herbal medicine, acupuncture, and Tuina massage) to standard continuous positive airway pressure (CPAP) therapy can provide superior benefits compared to CPAP alone for…
- Trial name
- NCT07061171
- Testing
- Continuous Positive Airway Pressure, Herbal Decoction, Acupuncture
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Weihua Peng
Pediatric Cancer, Hematologic Malignancies
Murottal as Adjunctive Intervention in Pediatric
This study aims to evaluate whether listening to the recitation of Surah Ar-Rahman (Murottal) before bedtime can help improve anxiety and sleep quality in hospitalized children with blood cancer.
- Conditions
- Pediatric Cancer, Hematologic Malignancies, Anxiety, Sleep Disturbances in Children
- Trial name
- NCT07861477
- Testing
- Murottal Intervention
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Airlangga
Myalgic Encephalomyelitis
Effect of CoQ10 Plus Selenium Supplementation on Clinical Outcomes and Biochemical Markers in ME/CFS (CoSeME Study)
In recent years, it has been suggested that nutritional deficiencies may be of causal relevance in individuals with ME/CFS. These include deficiencies of vitamins and trace elements.
- Trial name
- CoSeME (NCT05128292)
- Testing
- CoQ10 plus Selenium
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Sleep Disturbance, Aging
Chronic Moderate Sleep Restriction in Older Adults
Higher rates of mortality have been found both in short sleepers (< 6 hr/night) and long sleepers (> 8 hr/night), but there has been little experimental investigation of the effects of chronic, moderate sleep loss in long or…
- Trial name
- MSSS (NCT01642719)
- Testing
- Sleep restriction, Non-sleep restriction
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles