Clinical trials: Disturbed Sleep
Sleep Wake Disorders, Lung Transplantation
Low-Frequency rTMS for In-Hospital Sleep Disturbance After Lung Transplantation
This randomized, double-blind, sham-controlled trial will evaluate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) can improve in-hospital sleep quality in adult lung transplant recipients during early…
- Trial name
- TMS-SLEEP-LTx (NCT07796425)
- Testing
- Active Low-Frequency Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 152 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Sleep Disturbances in Smith-Magenis Syndrome
Development of Clinical Database of Individuals With Smith-Magenis Syndrome and Sleep Disturbances
This database will be used to better understand the sleep problems of people with SMS. This clinical database will be a part of a larger Smith-Magenis Patient Registry used to create an awareness campaign around SMS and the sleep…
- Trial name
- NCT03154697
- Testing
- Data collection of sleep disturbances in individuals with SMS
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Vanda Pharmaceuticals
Sleep Disorders, Fibromyalgia
The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia
Fibromyalgia is a condition of chronic widespread pain, sleep disturbance and fatigue. Most of the patients with fibromyalgia complain of either non-restorative sleep or complaints of disturbed sleep due to pain.
- Conditions
- Sleep Disorders, Fibromyalgia, Sleep
- Trial name
- NCT01234675
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Mansoor Ahmed M.D.
Autism Spectrum Disorder
Clonidine for Sleep Disturbances in Children With Autism Spectrum Disorder
Sleep disturbance has been reported in 44-86% of children with autism spectrum disorder (ASD) and is the source of considerable stress for the affected individual and family.
- Trial name
- NCT02812368
- Testing
- Clonidine
- Where
- United States
- Sponsor
- Ohio State University
Peri-menopausal Women, Sleep Disturbances
Study of Effects of Dao-In Exercise on the Perimenopausal Women With Sleep Disturbance
Among health problems of peri-menopausal women, sleep disturbances is very common complaint. The aim of this study is to realize the body constitution of the peri-menopausal women with sleep disturbance; and to evaluate the…
- Conditions
- Peri-menopausal Women, Sleep Disturbances, Dao-in Exercise, Body Constitution
- Trial name
- NCT02541318
- Testing
- Duo-in exercise
- Where
- 4 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- China Medical University Hospital
Addison Disease
Does Relative Hypoglycaemia &/or Sleep Disturbance Contribute to the Lethargy Observed in Addison's Disease
Addison's disease is a condition that leads to a reduction in production of steroid hormones from the adrenal glands. These hormones, particularly cortisol have many important roles in the body, one of which is increasing blood…
- Trial name
- NCT05515055
- Testing
- Blood test
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea
FIBRotic Interstitial Lung Disease and Nocturnal OXygen
Home sleep studies - which allow the measurement of breathing while the person sleeps - will be performed on patients with fibrotic interstitial lung disease attending two of the UK's largest respiratory medicine services.The…
- Conditions
- Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea, Sleep Disturbance, Sleep Hypoventilation
- Trial name
- FIBRINOX (NCT04586946)
- Where
- 2 sites in United Kingdom
- Volunteers
- 102 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Mild Depression, Anxiety State
MyCompass in a Swedish Context - an Automated Self-help Intervention Targeting Mental Health Problems
The study present findings from the implementation of myCompass, a fully automated self-help intervention of Australian origin for mild to moderate anxiety and depression, in a Swedish context.
- Conditions
- Mild Depression, Anxiety State, Sleep Disturbance, Stress, Psychological
- Trial name
- NCT03659630
- Testing
- MyCompass, Comparison group
- Volunteers
- 837 people
- Sponsor
- Karolinska Institutet
Sleep Initiation and Maintenance Disorders, Stress Disorders, Posttraumatic
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Post-traumatic stress disorder (PTSD) is a common consequence of combat that can result in trauma-related hyperarousal and sleep disturbances.
- Trial name
- NCT03642028
- Testing
- Suvorexant
- Where
- 4 sites in United States
- Volunteers
- 190 people
- Sponsor
- VA Office of Research and Development
Knee Osteoarthritis, Sleep Disturbance
Neuropathic Pain and it's Relation to Sleep Quality in Knee Osteoarthritis
The primary aim is to investigate the frequency and severity of neuropathic pain and its association with night pain in patients with knee osteoarthritis. For this purpose a progressive longitudinal study design was planned.
- Conditions
- Knee Osteoarthritis, Sleep Disturbance, Neuropathic Pain
- Trial name
- NCT06430918
- Testing
- physical examination, questionnaires and inventories
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bozyaka Training and Research Hospital
Sleep Disturbance, Insomnia
Brief Telehealth CBT-I Intervention in the Context of the COVID-19 Pandemic
The purpose of this study is to investigate whether an empirically validated treatment for insomnia (CBT-I) administered early in the course of sleep disturbance can prevent insomnia disorder or lessen negative mental health…
- Trial name
- NCT04409743
- Testing
- Remote Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Stanford University
Schizophrenia
FYS Study: Epidemiological, Multicentre, Cross-sectional Study in a Clinical Practice Environment, About the Relationship Between Functioning Status and the Quality of Sleep Perceived by Schizophrenic Outpatients in Spain
The purpose of this study is to establish the relationship between performance of patients with schizophrenia and relationship with perceived quality of sleep.
- Trial name
- NCT01376492
- Testing
- Functioning assessment, Quality of sleep assessment
- Volunteers
- 709 people
- Sponsor
- Janssen-Cilag, S.A.
Crohn's Disease, Inflammatory Bowel Disease
GI Symptoms and Sleep Disturbances in Patients With Quiescent Crohns Disease
In this study we would like to clarify the effect of long lasting Crohn's Disease on motility of the gastrointestinal system in patient and the effect regarding sleep disturbances.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Sleep Disturbances
- Trial name
- NCT02245594
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Autism Spectrum Disorder, Sleep Disorder
Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances
This is a multicenter, open-label study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon in treating sleep disturbances in pediatric and adult participants with ASD.
- Conditions
- Autism Spectrum Disorder, Sleep Disorder, Neurological Disorder, Sleep Disturbance
- Trial name
- NCT05361707
- Testing
- Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vanda Pharmaceuticals
Sleep, Sleep Disturbance
Radicle Rest 2: A Study of Health and Wellness Products on Sleep and Health Outcomes
A randomized, blinded, placebo-controlled direct-to-consumer study assessing the impact of health and wellness products on sleep and other health outcomes.
- Conditions
- Sleep, Sleep Disturbance, Sleep Disorder
- Trial name
- NCT05657808
- Testing
- Rest Study Active Product 1.1 Usage, Rest Study Active Product 1.2 Usage, Rest Study Active Product 2.1 Usage
- Where
- United States
- Volunteers
- 4,152 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Sleep Apnea Syndrome, Obstructive, Sleep Apnea Syndrome (OSAS)
The SNORE-trial: Analysis of Alterations in Sleep Stages Following Anesthesia and Their Relation to the Severity of Obstructive Sleep Apnea in the First 3 Nights After Surgery
The goal of this observational study is to learn about the relationship between sleep alterations following anesthesia and their relationship to a potential increase of obstructive sleep apnea (OSA) severity.
- Trial name
- SNORE (NCT06586268)
- Where
- 2 sites in Netherlands
- Volunteers
- 35 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Supraspinatus Injury, Sleep Disturbance
Conservative Treatment in Patients With Supraspinatus Tendon Injury.
Rotator cuff injuries are a major cause of severe pain, often significantly impacting patients\' sleep quality. For patients waiting for surgery or those not eligible for operative treatment, conservative treatment is…
- Trial name
- NCT06631976
- Testing
- 1ml of Depo-Medrol® injection, Rehabilitation, Nerve block with 4ml of 2% lidocaine
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Lodz
Sleep Disturbance
Human Centric Lighting to Improve Patient Sleep Parameters
Human centric lighting (HCL) is a technology that supports the body's circadian rhythm, as it can stimulate the sleep triggering hormone, melatonin, to improve sleep hygiene over standard lighting (SL), and promote recuperative…
- Trial name
- NCT05039749
- Testing
- Human Centric Lights
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Landstuhl Regional Medical Center
Survivorship, Cognitive Dysfunction
Biobehavioral Correlates of Cancer-related Cognitive Dysfunction and Its Co-occurring Symptoms
This descriptive, cross-sectional study will evaulate and fully characterize factors associated with cognitive dysfunction in Breast Cancer (BCS) and Colorectal Cancer (CRC) survivors that have cognitive concerns, and factors…
- Conditions
- Survivorship, Cognitive Dysfunction, Pain, Depression
- Trial name
- NCT04611620
- Testing
- Cognitive Dysfunction
- Where
- United States
- Volunteers
- 682 people
- Sponsor
- Indiana University
Fatigue, Cognitive Function
Radicle Energy VBMTM: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes
Radicle Energy VBMTM: A randomized, double-blind, placebo- controlled direct-to-consumer study assessing the impact of health and wellness products on fatigue and related health outcomes.
- Conditions
- Fatigue, Cognitive Function, Global Mental Health, Sleep Disturbance
- Trial name
- NCT07653724
- Testing
- Energy Active Product 1
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Radicle Science