Clinical trials: Disturbed Sleep
Sleep Disturbance, Sleep Disorder
Efficacy of a Sleep Hygiene Toolkit for Patients in ARU
Sleep Hygiene Study Abstract: INTRODUCTION Sleep is integral to the health of a person and can have multifaceted contributions to a person including their physical, cognitive, and psychosocial well-being.
- Conditions
- Sleep Disturbance, Sleep Disorder, Insomnia, Critical Illness Myopathy
- Trial name
- NCT05541692
- Testing
- Sleep Hygiene Toolkit
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Sleep, Sleep Disturbance
WEsleep Trial: Improving Sleep in Hospitalized Patients
In the WEsleep study, the investigators will perform a cluster randomized controlled trial. 3 surgical and 3 medical departments will be randomized to implement low-cost and simple interventions aimed at improving sleep in…
- Conditions
- Sleep, Sleep Disturbance, Sleep Hygiene, Circadian Dysrhythmia
- Trial name
- WEsleep (NCT05683483)
- Testing
- WEsleep Interventions
- Where
- Netherlands
- Volunteers
- 396 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Sleep Apnea Syndrome
Stair Stepping Exercise Training in Patients With Obstructive Sleep Apnea Syndrome
This 3-year prospective, randomized, control, longitudinal study is aimed to (1) examine the effect of stair stepping exercise training on cardiopulmonary fitness and sleep situation in patients with Obstructive Sleep Apnea…
- Trial name
- NCT00952172
- Testing
- stair stepping exercise
- Volunteers
- 47 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer, Sleep
Impact of Sleep Disturbance on Cognition and Quality of Life in Breast Cancer
Patients treated for breast cancer frequently complain of sleep disturbances, about 40% of them. Of the sleep disturbances experienced by patients, insomnia is the most common complaint.
- Conditions
- Breast Cancer, Sleep, Quality of Life
- Trial name
- ICANSLEEP (NCT05414357)
- Testing
- Functional Magnetic Resonance Imaging at rest and in activation with attentional task
- Where
- 2 sites in France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
Sleep, Sleep Disorders
Z-Drugs for Sleep Disorders in Alzheimer's Disease
The purpose of this study is to determine whether Zolpidem and Zoplicone are efective in the treatment of sleep disorders in Alzheimer's disease (AD)
- Conditions
- Sleep, Sleep Disorders, Insomnia, Alzheimer's Disease
- Trial name
- NCT03075241
- Testing
- Zolpidem, Zoplicone
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Brasilia University Hospital
Parkinsons Disease
First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)
This study is researching an experimental drug called ALN-SNCA (called "study drug"). The study is focused on people with early Parkinson's disease, a disorder of the nervous system that affects movement.
- Trial name
- NCT07216066
- Testing
- ALN-SNCA
- Where
- 3 sites in Canada, Netherlands
- Volunteers
- 46 people
- Sponsor
- Regeneron Pharmaceuticals
Advanced Parkinson's Disease
A Study to Assess Change in Sleep Disturbances of Adult Participants With Advanced Parkinson's Disease Receiving Subcutaneous Foslevodopa/Foscarbidopa
Parkinson's disease (PD) is a neurological condition, which affects the brain. Some symptoms of PD are tremors, stiffness, and slowness of movement.
- Trial name
- ONIROS (NCT07284342)
- Where
- 16 sites in Spain
- Volunteers
- 103 people
- Sponsor
- AbbVie
Parkinson Disease
Parkinson's Disease Progression Study
Disease Progression Study
- Trial name
- NCT06219629
- Where
- 10 sites in United States
- Volunteers
- 82 people
- Sponsor
- Koneksa Health
Chronic Fatigue Syndrome
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
The main aim of the study is to examine the effect of oral CoQ10 plus NADH (Reconnect®) supplementation twice daily for 8-weeks on the changes in fatigue perception, sleep disturbances, autonomic dysfunction and HRQoL assessed by…
- Trial name
- CONNeCT (NCT03186027)
- Testing
- Coenzyme Q10 plus NADH, phosphoserine plus vitamin C
- Where
- Spain
- Volunteers
- 282 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Parkinson's Disease
Menthol for Improving Movement and Sleep in Parkinson's Disease Patients
Parkinson's disease (PD) is a progressive neurological disorder characterized by both motor and non-motor symptoms due to the degeneration of dopamine-producing neurons. There is currently no cure.
- Trial name
- NCT07294469
- Testing
- Menthol gloves and socks
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University Hospital
Brain Injuries, Sleep Disturbance
Music Listening and Sleep in Rehabilitation of People With Acquired Brain Injury
An Injury to the brain may lead to sleep-wake disturbances which may negatively influence functional recovery, quality of life and general rehabilitation.
- Trial name
- NCT05620069
- Testing
- Music listening
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Vejlefjord Rehabilitation
Bullous Pemphigoid (BP)
Prevalence of Sleep Disturbances in Bullous Pemphigoid Patients.
Bullous pemphigoid (BP) is the most common autoimmune blistering disorder. The incidence of BP has increased due to increased life expectancy, particularly in developed countries, which can be associated with multiple geriatric…
- Trial name
- SLEEP-BP (NCT07188402)
- Testing
- Prevalence of sleep disturbances in patients with bullous pemphigoid, Prevalence of sleep disturbances in healthy volunteers without bullous pemphigoid
- Where
- France
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Critical Illness, Delirium
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
Up to 25% of intensive care unit (ICU) survivors experience cognitive impairment comparable in severity to mild Alzheimer's disease and related dementias after hospital discharge.
- Conditions
- Critical Illness, Delirium, Cognitive Impairment, Cognitive Decline
- Trial name
- SLEEP-COG (NCT06411561)
- Testing
- SLEEP + COG, COG, SLEEP
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Autism, Autism Spectrum Disorders
Treatment of Sleep Disturbances in Young Children With Autism
This study will compare the efficacy of a behavioral parent training program (PT) aimed specifically at common sleep disturbances compared to parent education (PE) program focusing on general issues related to autism.
- Trial name
- NCT01322022
- Testing
- ParentTraining, Parent Education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders
The objective of this K01 study was to pilot a sequential, multiple assignment, randomized trial (SMART) design to compare the impact of a sequence of sleep interventions, based on participant treatment response, to optimize…
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Sleep Disturbance
- Trial name
- NCT03730194
- Testing
- Melatonin, Bedtime Bank
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Cancer
Calm for Cancer Sleep Disturbance
Cancer and cancer treatment often lead patients and survivors to experience a host of chronic symptoms, of which sleep disturbances are a major concern.
- Trial name
- NCT04345068
- Testing
- Calm Meditation Mobile App, Health Education Podcast Mobile App
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Depression
The Efficacy of a Depression Intervention for Adolescents With Depression and Sleep Disturbances
The focus of this study is on identifying how Interpersonal Psychotherapy for Adolescents (IPT-A) with depression works to change sleep and related biological markers found in saliva, namely cortisol and pro-inflammatory cytokine…
- Trial name
- NCT02429674
- Testing
- TranS-C and IPT-A
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- New York State Psychiatric Institute
Sleep Disturbance
Citrus Extract, Sleep and Mental Wellbeing
This is a randomized, double-blind, placebo-controlled, cross-over trial investigating the effects of daily administration of citrus extract on sleep and mental wellbeing.
- Trial name
- NCT06239168
- Testing
- Citrus extract, Maltodextrin
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Insomnia Due to Mental Disorder
Evaluation of the ChronoS Therapy on the Severity of Sleep Disturbances Among Patients With Mood Disorders: A Within-subjects Study
A new psychotherapy has been developed within the Psychiatry, Sleep and Chronobiology Reference Center (ChronoS) since January 2022.Results have shown relevant clinical interest on insomnia symptoms, as well on mood, anxiety and…
- Trial name
- CRHONOS (NCT07180290)
- Testing
- Psychotherapy
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Centre Hospitalier St Anne
IMSOMNIA, Sleep Disturbance
Sleep Optimization With Acoustic Therapy
Insomnia is a highly prevalent sleep disorder characterized by persistent difficulty initiating or maintaining sleep, often accompanied by impaired daytime functioning.
- Trial name
- SONATA (NCT07503223)
- Testing
- Personalized Sound Therapy
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia