Clinical trials: Disturbed Sleep, open to volunteers
Carcinoma, Non-Small-Cell Lung, Sleep Wake Disorders
Low-Frequency rTMS for In-Hospital Sleep Disturbance in Advanced NSCLC
This randomized, double-blind, sham-controlled trial will evaluate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) can improve in-hospital sleep quality in adults with advanced non-small cell lung cancer…
- Trial name
- NCT07796438
- Testing
- Active Low-Frequency Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 160 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Autism, Sleep Disturbances in Children
Differences in Rest, Emotion, and Arousal Modulation in Youth
The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10).
- Conditions
- Autism, Sleep Disturbances in Children, Sleep
- Trial name
- DREAMY-Autism (NCT07476937)
- Testing
- Power Down bedtime manipulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Cancer-related Problem/Condition, Fatigue in Cancer Survivors
Decentralized Clinical Trial of Effectiveness of EnergyPoints App in Cancer Survivors
The purpose of the study is to evaluate whether EnergyPoints, a mobile phone health app that guides the participant to do self-acupressure, can decrease fatigue and improve sleep.
- Conditions
- Cancer-related Problem/Condition, Fatigue in Cancer Survivors, Sleep Disturbances, Health-related Quality of Life
- Trial name
- NCT06754722
- Testing
- App to guide self-acupressure
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- 5 Point App, Inc.
Alzheimer Disease, Dementia
Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals With Alzheimer's Disease
This study seeks to evaluate the utility and efficacy of the Non-Contact Sleep Quality Monitor System when used to monitor the sleep quality of individuals living in long-term care (LTC) with either Alzheimer's Disease (AD) or…
- Conditions
- Alzheimer Disease, Dementia, Sleep Disturbance
- Trial name
- NCT06045988
- Testing
- Non-Contact Sleep Quality Monitor System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Parkinson's Disease
Menthol for Improving Movement and Sleep in Parkinson's Disease Patients
Parkinson's disease (PD) is a progressive neurological disorder characterized by both motor and non-motor symptoms due to the degeneration of dopamine-producing neurons. There is currently no cure.
- Trial name
- NCT07294469
- Testing
- Menthol gloves and socks
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University Hospital
Autism Spectrum Disorder, Sleep Disturbance
Internet-delivered Cognitive Behaviour Therapy for Sleep Problems in ASD
This trial investigates the behavioural effects of Internet-based Cognitive behaviour therapy for insomnia (CBT-I) in adolescents with autism spectrum disorder with sleep problems. This is a randomised controlled trial.
- Conditions
- Autism Spectrum Disorder, Sleep Disturbance, Insomnia
- Trial name
- NCT03624400
- Testing
- Internet-based CBT-I, Internet-based psychoeducation
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Stockholm University
Violent Suicide Attempts in Adolescents
Mentalization and Social Cognition in Adolescents After Suicide Attempt
This study investigates the risk of violent suicide attempts in adolescents, with a particular focus on social cognition and sleep disturbances, to better understand the cognitive and behavioral mechanisms involved and to inform…
- Trial name
- MENTACOG-TS (NCT07688798)
- Testing
- Test, Questionnaires
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thoracic Surgical Procedures
Sodium Oxybate for Postoperative Sleep Disturbance After Thoracic Surgery
This is a single-center, randomized, double-blind, placebo-controlled trial. Three hundred-sixty adult patients undergoing elective thoracoscopic surgery will be randomly allocated at a 1:1 ratio to receive either intraoperative…
- Trial name
- NCT07794982
- Testing
- sodium oxybate
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Jingsheng Lou
Preoperative, Sleep Disturbance
Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer
Previous studies have indicated a high incidence of sleep disturbances and anxiety symptoms in individuals with colorectal cancers prior to undergoing surgery, leading to worsened postoperative pain, slower recovery, and higher…
- Conditions
- Preoperative, Sleep Disturbance, Anxiety, Midazolam
- Trial name
- POMPPR (NCT06407518)
- Testing
- Midazolam oral solution
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Obesity and Overweight, Type 2 Diabetes
Sleep, Glucose, and Brain Health in Obesity and Overweight Individuals
The primary aim of the NNF study is to investigate both cross-sectional and longitudinal associations between sleep patterns-measured over two consecutive weeks at baseline and again one year later-and indicators of glycemic…
- Conditions
- Obesity and Overweight, Type 2 Diabetes, Sleep, Brain Health
- Trial name
- NNF (NCT06968728)
- Volunteers
- 400 people
- Sponsor
- Uppsala University
Multiple Sclerosis, Sleep Disturbance
Reliability and Validity of the Turkish Version of General Sleep Disturbance Scale (GSDS-T) in Multiple Sclerosis
The GSDS-T was developed by Lee KA to assess difficulty falling asleep, waking up during sleep, sleep quality, and daytime alertnes.
- Trial name
- NCT06875908
- Testing
- Turkish Validity and Reliability of The GSDS-T in patients with multiple sclerosis
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Sleep Disturbance in Advanced Cancer
Sleep Well At Night
Research has shown that the incidence of sleep disturbances in people with cancer is much higher than in the general population. Sleep problems can lead to worse symptoms, quality of life, and potentially impact outcomes.
- Trial name
- SWAN (NCT07068971)
- Testing
- Online cognitive behavioural therapy for insomnia, bright light therapy, activity
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Our Lady's Hospice and Care Services
Sleep Disturbance, Sleep
Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)
The goal of this clinical trial is to adapt a sleep intervention for individuals representative of all demographic groups, including those who are at the highest risk for suicidal behavior.
- Conditions
- Sleep Disturbance, Sleep, Depression, Suicide
- Trial name
- NCT06963463
- Testing
- TranS-C, Sleep Feedback
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Pittsburgh
Sleep Disturbance, Fatigue Syndrome, Chronic
Bao Yuan Tang Extract and Galactooligosaccharides for Sleep Regulation
Certain classical formulas in traditional Chinese medicine and dietary prebiotics have demonstrated beneficial effects on various aspects of suboptimal health status in previous studies.
- Conditions
- Sleep Disturbance, Fatigue Syndrome, Chronic, Endocrine Disorder, Glucose Metabolism Disorder
- Trial name
- NCT07774897
- Testing
- Combination product (Bao Yuan Tang full-component extract 2.0g and galactooligosaccharides 2.0g), Galactooligosaccharides 2.0g
- Where
- 6 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Substance Abuse, Sleep Disturbances
Exploring Substance Use, Sleep Disturbances and Reward Sensitivity
According to foreign medical studies, substance use is closely related to reward sensitivity and sleep patterns. The purpose of this research is to understand the relationship between these three factors, which will help improve…
- Trial name
- NCT07028346
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Volunteers
- 154 people
- Sponsor
- Kwai Chung Hospital
Hepatic Encephalopathy, Covert Hepatic Encephalopathy
Affect of Melatonin on Sleep and Cognition in Cirrhosis
The goal of this clinical trial is to learn the affect of melatonin on sleep, cognitive function, and quality of life (QoL) in patients with cirrhosis and a complication called hepatic encephalopathy (HE).
- Conditions
- Hepatic Encephalopathy, Covert Hepatic Encephalopathy, Cirrhosis, Sleep Disturbances and Insomnia
- Trial name
- SNORE-HE (NCT07046429)
- Testing
- Melatonin tablet 3 mg once daily, Thiamine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Weill Medical College of Cornell University
Occupational Burnout, Work-Related Stress
Virtual Mindfulness and Breathing Training for Stress, Burnout, Sleep, and Cognition in Rotating-Shift Nurses
This randomized controlled trial aims to evaluate the effectiveness of a mobile- and virtual reality-based mindfulness and breathing intervention on stress, burnout, sleep quality, and cognitive function among Rotating-shift…
- Conditions
- Occupational Burnout, Work-Related Stress, Sleep Disturbance, Cognitive Dysfunction
- Trial name
- NCT07028788
- Testing
- Health Education Material, Mobile-Based Mindfulness, Mobile-Based Mindfulness combined with Breathing
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Shih-Chin
Liver Cirrhosis, Sleep Disturbance
Daridorexant for Sleep Disturbance in Adults With Liver Cirrhosis
This study will evaluate the efficacy and safety of daridorexant, a dual orexin receptor antagonist, in adults with liver cirrhosis and sleep disturbance, including participants with or without covert hepatic encephalopathy.
- Conditions
- Liver Cirrhosis, Sleep Disturbance, Hepatic Encephalopathy
- Trial name
- NCT07830303
- Testing
- Daridorexant
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Wang Fengmei
Stem Cell Transplant Complications, Sleep Disturbance
Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients
Pediatric patients undergoing stem cell transplant (SCT) are hospitalized for extended periods and are at high risk for sleep disturbances.
- Trial name
- DREAMS (NCT06468618)
- Testing
- DREAMS Program Video and Care Kit
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Postoperative Sleep Disturbance, Orthopedic Surgery Patients
Effect of ASMR and White Noise on Sleep Quality in Patients Undergoing Elective Lower Extremity Surgery
This randomized controlled trial aims to evaluate the effects of Autonomous Sensory Meridian Response (ASMR) and white noise on postoperative sleep quality in patients undergoing elective lower extremity surgery.
- Conditions
- Postoperative Sleep Disturbance, Orthopedic Surgery Patients, Sleep Quality
- Trial name
- SLEEP-ASMR (NCT07651228)
- Testing
- ASMR Audio Intervention, White Noise Audio Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- muzeyyen ataseven