Clinical trials: Diuresis
Automated Urine Monitoring, Urine Output
Gravity in Flow: Automating Diuresis
The goal of this randomized clinical trial is to evaluate the accuracy of automated urine output monitoring using the FlowSure system compared to standard manual urine monitoring in hospitalized patients with an indwelling…
- Conditions
- Automated Urine Monitoring, Urine Output, Fluid Balance, Urinary Catheters
- Trial name
- NCT07384325
- Testing
- FlowSure Automated Urine Output Monitor, Manual Urine Monitoring System
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Congestive Heart Failure
Reprieve ADHF EFS IDE
This is a prospective, single arm, early feasibility study (EFS) designed to evaluate the safety and device performance of The RenalGuard System in the management of patients admitted with signs and symptoms of congestive heart…
- Trial name
- NCT03866551
- Testing
- Reprieve Cardiovascular System
- Volunteers
- 40 people
- Sponsor
- CardioRenal Systems, Inc.
Heart Decompensation, Acute, Acute Kidney Injuries
POCUS-Guided Diuresis for Decompensated Heart Failure
Heart failure occurs when the heart cannot pump blood effectively, leading to fluid buildup in the body. This can cause problems such as difficulty breathing, swelling, and extreme tiredness.
- Trial name
- POCUSHF-GD (NCT06921603)
- Testing
- Furosemide (Standard Diuretic) Treatment, POCUS-Assessed Diuretic Management
- Where
- 5 sites in United States
- Volunteers
- 588 people
- Sponsor
- University of Pittsburgh
Urinary Incontinence,Stress, Fecal Incontinence
Effects of Single Dose Tadalafil on Urethral and Anal Closure Function
The purpose of the trial is to assess the effect of tadalafil compared to placebo (inactive comparator) on the urethral - and anal pressure and on urine flow in healthy females.
- Trial name
- NCT05095077
- Testing
- Tadalafil 40 MG
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Contrast Induced Nephropathy
Induced Diuresis With Matched Hydration Compared to Standard Hydration for Contrast Induced Nephropathy (CIN) Prevention
This study is being proposed with the objective to assess the potential benefits of induced diuresis by furosemide with matched hydration therapy compared to standard hydration in the prevention of contrast-induced nephropathy…
- Trial name
- MYTHOS (NCT00702728)
- Testing
- Furosemide and matched saline hydration, isotonic saline solution
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Centro Cardiologico Monzino
Kidney Stone
Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser
In view of the positive results of the numerous studies conducted on forced diuresis after extra-corporeal lithotripsy, the investigators chose to evaluate forced diuresis by injection of Furosemide associated with intravenous…
- Trial name
- FIREStones (NCT05916963)
- Testing
- Furosemide 40 mg
- Where
- 9 sites in France
- Volunteers
- 374 people
- Sponsor
- University Hospital, Tours
Cardiorenal Syndrome
Volume Optimization Incorporating Negative Pressure Diuresis in Heart Failure (VOID-HF)
The Cardiorenal Syndrome during Acute decompensated heart failure (ADHF) with persistent congestion despite high dose IV diuretic therapy is associated with remarkable morbidity, which can include the need for renal dialysis or…
- Trial name
- VOID-HF (NCT04227977)
- Testing
- JuxtaFlow System
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- 3ive Labs
Kidney Diseases, Congestive Heart Failure
Brain Natriuretic Peptide (BNP) to Preserve Renal Function in Hospitalized Patients With Heart Failure
Patients hospitalized for treatment of decompensated heart failure (CHF) are at risk for prolonged length of stay (LOS) and frequent readmissions.
- Conditions
- Kidney Diseases, Congestive Heart Failure, Cardiomyopathy
- Trial name
- NCT00170183
- Testing
- Nesiritide
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Mayo Clinic
Acute Heart Failure (AHF)
Protocolised Natriuresis-Guided Decongestion at Different Diuretic Intensities in Acute Heart Failure
The goal of this clinical trial is to learn how different doses of a water-removing medicine (diuretic) work in adults admitted to hospital with acute heart failure. It will also assess the safety of these treatment approaches.
- Trial name
- DESTINaTE-AHF (NCT07804654)
- Testing
- Furosemide - HIGH-dose Natriuresis-Guided Strategy, Furosemide - LOW-dose Natriuresis-Guided Strategy, Loop Diuretic - Standard of Care
- Where
- Malaysia
- Volunteers
- 109 people
- Sponsor
- Universiti Teknologi Mara
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Ultrasound IPP to Predict Response to Medical Therapy in LUTS/BPH
This prospective cohort study evaluated whether transabdominal ultrasound measurement of intravesical prostatic protrusion predicts symptom severity and response to medical therapy in men aged 50 years or older with lower urinary…
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Bladder Outlet Obstruction
- Trial name
- NCT07306767
- Testing
- Transabdominal ultrasound measurement of intravesical prostatic protrusion, Alpha-adrenergic blocker, 5-alpha reductase inhibitor
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Lower Urinary Tract Symptoms
The Effect of Diuresis During 20-minute Pad Test on the Estimation of the Severity of Stress Urinary Incontinence
The aim of this study is to estimate the amount of extra urine produced by natural diuresis during 20-minute pad test, and assess the effect of diuresis on the accuracy of using 20-minute pad test to estimate the severity of SUI.
- Trial name
- NCT02126618
- Where
- Taiwan
- Volunteers
- 3,000 people
- Sponsor
- National Taiwan University Hospital
Urinary Retention
Comparison of Urinary Flow Study
The purpose of this research study is to compare the urinary flow speed of two different female catheters in patients that use intermittent catheters to empty their bladder.
- Trial name
- NCT06918067
- Testing
- Coloplast Micro Zone Luja Female Catheter, Coloplast SpeediCath Female Catheter
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Wake Forest University Health Sciences
Heart Failure, Congestive
Placebo-Controlled Randomized Study of KW-3902 for Subjects Hospitalized With Worsening Renal Function and Heart Failure Requiring IV Therapy
To evaluate the effect of KW-3902IV, in addition to standard therapy, on the proportion of worsening heart failure and worsening renal function, and on the proportion of deaths or rehospitalizations for heart failure or worsening…
- Trial name
- REACH UP (NCT00443690)
- Testing
- rolofylline
- Volunteers
- 480 people
- Sponsor
- NovaCardia, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Chronic Kidney Insufficiency, Hemodialysis Treatment
Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function
Introduction: Chronic kidney disease is characterized by a progressive deterioration of renal function. At the end of the progression, when complications occur (overhydration, electrolyte imbalances or retention of uremic…
- Conditions
- Chronic Kidney Insufficiency, Hemodialysis Treatment, Diuresis Preserved
- Trial name
- RRF (NCT01977430)
- Testing
- Hydrochlorothiazide and furosemide
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Corporacion Parc Tauli
Congestive Heart Failure Exacerbation, Renal Insufficiency
BNP for Cardio-Renal Decompensation Syndrome (BNP-CARDS)
Many patients with exacerbations of heart failure have significant concomitant kidney dysfunction. The combination of these two conditions makes pharmacological management difficult.
- Trial name
- NCT00186329
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Radiographic Contrast Agent Nephropathy, Aortic Valve Stenosis With Insufficiency
The Effect of the Forced Diuresis With Matched Hydration in Reducing Acute Kidney Injury During TAVI
Evaluating whether forced diuresis with matched hydration will reduce the risk of contrast induced nephropathy in patients undergoing Transcatheter Aortic Valve Implantation (TAVI).
- Trial name
- REDUCE-AKI (NCT01866800)
- Testing
- Renal Guard, Conventional Treatment
- Where
- Israel
- Volunteers
- 136 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Renal Calculi
External Physical Vibration Lithecbole(EPVL) Versus Traditional Row of Stone After Retrograde Intrarenal Surgery(RIRS)
The treatment of renal calculus by retrograde intrarenal surgery(RIRS) isn't able to eliminate stone completely, hastening fragments clearance just only rely on traditional expulsive methods such as high fluid intake ,increasing…
- Trial name
- NCT02645708
- Testing
- Retrograde Intrarenal Surgery, EPVL after RIRS
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Cardiomyopathy, Congestive Heart Failure
AiDing Diuresis wIth Tolvaptan (ADD-IT)
The purpose of this study is to test the use of tolvaptan (commercial name Samsca) when given in addition to intravenous (IV) diuretics early during an episode of acute heart failure.
- Trial name
- ADD-IT (NCT02646540)
- Testing
- Tolvaptan 30 mg + IV Diuretics, Metolazone 5 mg + IV Diuretics, 2.5 times the Diuretics Dose
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Edema, Hypoproteinemia
Furosemide and Albumin for Diuresis of Edema: A Pilot Randomized Controlled Trial
Critically ill patients usually require intravenous fluids to correct low blood pressure and improve blood flow to vital organs.
- Trial name
- FADE (NCT02055872)
- Testing
- Intravenous albumin, Normal saline
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Hamilton Health Sciences Corporation
Diuresis, Bladder Retention Volume
Effect of Preload on Bladder Retention Volume During Spinal Anesthesia
The purpose of this study is to assess the influence of different fluid infusions on the quantity of bladder retention after spinal anesthesia.
- Conditions
- Diuresis, Bladder Retention Volume, Hypotension
- Trial name
- NCT00550186
- Testing
- Ringers Lactate, HaemoHES 6%
- Where
- Netherlands
- Volunteers
- 144 people
- Sponsor
- Rijnstate Hospital