Clinical trials: Diuretics
Primary Hypertension
Nijmegen Antihypertensive Management Improvement Study
High blood pressure is an important risk factor for diseases of heart and blood vessels like myocardial infarction and stroke. Many patients are not treated to target blood pressures, even though good blood pressure lowering…
- Trial name
- NAMIS (NCT00457483)
- Testing
- hydrochlorothiazide, valsartan, 80 mg once-a-day
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Radboud University Medical Center
Pulmonary Embolism With Right Ventricle Enlargement
Diuretic Versus Placebo in Pulmonary Embolism
Pulmonary Embolism (PE) is a frequent and severe disease with an annual incidence of about 75000 cases in France and a short-term mortality rate of about 10%.
- Trial name
- DiPER (NCT02268903)
- Testing
- Diuretics : Furosemide
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Heart Failure
Optimal Diuretic Therapies for Acute Heart Failure With Volume Overload
This trial aims to identify the best strategy for treating acute heart failure (AHF) with volume overload in patients at risk of diuretic resistance.
- Trial name
- DRAIN-AHF (NCT06166654)
- Testing
- Acetazolamide, Metolazone 2.5 MG
- Where
- 6 sites in Denmark
- Volunteers
- 939 people
- Sponsor
- Johannes Grand
Hypertension, Peritoneal Dialysis
Blood Pressure Control With Thiazide Diuretics in Peritoneal Dialysis Patients
To evaluate the blood pressure lowering effects of thiazide diuretics in patients on peritoneal dialysis
- Conditions
- Hypertension, Peritoneal Dialysis, End Stage Kidney Disease (ESRD)
- Trial name
- NCT07271420
- Testing
- Hydrochlorothiazide 25mg once per day
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Leukemia
Ultrafiltration (Aquapheresis) in Patients With Leukemia and Severe Fluid Overload
The goal of this clinical research study is to learn about the safety and level of effectiveness of aquapheresis compared to diuretic drugs. Diuretic drugs are designed to help the kidneys to form more urine.
- Trial name
- NCT01508260
- Testing
- Aquapheresis, Furosemide
- Sponsor
- M.D. Anderson Cancer Center
Acute Heart Failure (AHF)
TACTIC-HF: Sequential Diuretic Strategies in Ambulatory Worsening Heart Failure
TACTIC-HF is a prospective randomized crossover trial designed to compare three ambulatory diuretic strategies in patients with worsening heart failure treated in a specialized heart failure day-hospital program.
- Trial name
- TACTIC-HF (NCT07593612)
- Testing
- Intravenous furosemide bolus injections, ACETAZOLAMIDE oral capsule, Hydrochlorothiazide (HCT)
- Volunteers
- 60 people
- Sponsor
- Lucrecia Maria Burgos
Hypertension
Comparison of Single and Combination Diuretics in Low-Renin Hypertension
The purpose of this study is to determine whether the routine combination of optimal thiazide and K+-sparing diuretic will both increase efficacy of BP reduction and reduce risk of glucose intolerance; and whether K+-sparing…
- Trial name
- PATHWAY3 (NCT02351973)
- Testing
- Hydrochlorthiazide, Amiloride, Hydrochlorthiazide and Amiloride
- Where
- United Kingdom
- Volunteers
- 423 people
- Sponsor
- University of Cambridge
Hypertension, Hypotension
Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure
The purpose of this study is to determine whether continuing or discontinuing furosemide (a diuretic) on the day of elective noncardiac surgery for those who take furosemide on a chronic basis, causes more intraoperative…
- Conditions
- Hypertension, Hypotension, Edema, Congestive Heart Failure
- Trial name
- NCT00115726
- Testing
- furosemide
- Where
- 3 sites in United States, Canada
- Volunteers
- 198 people
- Sponsor
- University of Calgary