Clinical trials: Divergent Strabismus
Intermittent Exotropia
Full-Time Occlusion Therapy for Intermittent Exotropia in Children
Determine whether full-time patching is more effective than observation for improving distance control of IXT after 3 months of treatment (on-treatment outcome).
- Trial name
- IXT7 (NCT05462821)
- Testing
- Eye Patch
- Where
- 25 sites in United States
- Volunteers
- 73 people
- Sponsor
- Jaeb Center for Health Research
Intermittent Exotropia
Near Vergence Training for Distance Control in Intermittent Exotropia
Intermittent Exotropia (IXT) is a common type of eye misalignment where one eye periodically turns outward, and control is typically much worse when looking at objects far away than close up.
- Trial name
- NCT07642687
- Testing
- Home-based near eye training program
- Where
- Hong Kong
- Volunteers
- 42 people
- Sponsor
- The Hong Kong Polytechnic University
Esotropia, Exotropia
Comparison of Two Treatments for Strabismus Correction: Botulinum Toxin A Associated to Surgery and Surgery Alone
Two different treatments were given to large angle horizontal strabismus (eso and exotropia) adult patients who agree to participate of the study. Inform consents were required for participants.
- Trial name
- NCT01460355
- Testing
- Botulinum Toxin Type A, saline solution
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- University of Campinas, Brazil
Intermittent Exotropia
Symmetric vs Asymmetric BLR Recession in Management of Basic IXT With Ocular Dominance
The study aims to investigate ocular motor and sensory outcomes of two different strategies of lateral rectus recession; symmetric and asymmetric, in management of basic type intermittent exotropia with ocular dominance.
- Trial name
- IXT (NCT05234957)
- Testing
- Bilateral Lateral Rectus Recession
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Benha University
Strabismus, Nystagmus, Congenital
Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus.
- Trial name
- NCT04770519
- Testing
- whole genome sequencing or whole exome sequencing
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Boston Children's Hospital
Strabismus, Esotropia
Strabismus Surgery and Driving Ability
The strabismus impacts binocular visual acuity and stereoscopy. Thus, driving capacities of patients with strabismus may be reduced.
- Conditions
- Strabismus, Esotropia, Exotropia
- Trial name
- NCT02570555
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Alternating Exotropia
Bil. LR Rec. Using Standard Tables VS Reduced Numbers in Intermittent Exo. in Children Under 6
comparing the motor alignment and the incidence of postoperative esotropia following the correction of intermittent exotropia in children below 7 years by bilateral lateral rectus recession using the standard recession tables…
- Trial name
- NCT04308538
- Testing
- Standard Recession, Reduced Recession
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Intermittent Exotropia
Lateral Rectus Muscle and Anterior Segment Optical Coherence Tomography (AS-OCT)
•Background and study aims : The investigators conducted this study to evaluate the movement of extraocular muscle after strabismus surgery with non-invasive tool called AS-OCT.
- Trial name
- NCT02383381
- Testing
- lateral rectus recession
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Surgical Procedure, Unspecified, Ocular Discomfort
Lateral Rectus Muscle Tendon Elongation
To evaluate a technique using resected medial rectus muscle transplantation for elongation of Lateral rectus tendon as a monocular surgery for large angle sensory exotropia.
- Conditions
- Surgical Procedure, Unspecified, Ocular Discomfort, Strabismus, Divergent
- Trial name
- NCT04286945
- Testing
- LATERAL RECTUS MUSCLE AUGMENTED RECESSION BY ELONGATION OF THE TENDON WITH AUTOGRAFT FROM RESECTED MEDIAL RECTUS MUSCLE
- Volunteers
- 16 people
- Sponsor
- Tanta University
Exotropia
Evaluation of Exotropia After Patching the Eye or After Prism Adaptation
This study intends to determine the number and percent of subjects initially diagnosed with divergence excess exotropia which would be reclassified as simulated divergence excess exotropia if tested after 24 hours of monocular…
- Trial name
- DESDEE (NCT05242510)
- Testing
- Patching, Prism Adaptation
- Where
- 9 sites in United States, Canada and 3 more
- Volunteers
- 1 people
- Sponsor
- University of Rochester
Strabismus, Exotropia
A Novel Diagnostic Method for Exotropia Using Video-oculography
Thirty-four subjects with constant exotropia were included. Two independent ophthalmologists measured the angle of ocular deviation using alternate prism cover test (APCT).
- Trial name
- NCT03119311
- Testing
- Video-oculography, APCT
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Inje University
Exotropia
Study of Clinical Types and Surgical Out Come of Pediatric Exotropia
study aiming to evaluate all children presented to strabismus clinic in ophthalmology department at sohag university hospital with divergent squint (exotropia) and to record surgical outcome of those who underwent strabismus…
- Trial name
- NCT05089422
- Testing
- Squint surgery
- Volunteers
- 30 people
- Sponsor
- Sohag University
Intermittent Exotropia
Controlled Intermittent Alternate Occlusion (CIAO) Therapy for Intermittent Exotropia
To determine the effectiveness of alternate occlusion therapy for the treatment of IXT among patients aged 3 to < 11 years old.
- Trial name
- CIAO (NCT02466659)
- Testing
- CIAO therapy Amblyz glasses
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Indiana University
Intermittent Exotropia
A Pilot Clinical Trial of Overminus Spectacle Therapy for Intermittent Exotropia
The objective of this short-term, pilot randomized trial comparing 2.50 diopters (D) overminus lens treatment vs. non-overminus (spectacles without overminus or no spectacles) in children with intermittent exotropia (IXT) 3 to <7…
- Trial name
- IXT3 (NCT02223650)
- Testing
- Overminus treatment, Non-overminus treatment
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Jaeb Center for Health Research
Intermittent Exotropia
Improving Control of Alignment in Intermittent Exotropia
Aim 1: To determine whether use of dichoptic movies for 4 weeks may be helpful in improving control of alignment in children with intermittent exotropia (IXT), thus allowing IXT to be managed non-surgically Aim 2: To determine…
- Trial name
- NCT04199871
- Testing
- dichoptic 3D movies
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Retina Foundation of the Southwest
Intermittent Exotropia, Myopia Overcorrection
Overminus Lens Therapy in Intermittent
In this prospective study, entitled "The Long-Term Efficacy of Overminus Lens Therapy in Intermittent Exotropia",the investigators examined the long-term impact of overminus lenses on the management of intermittent exotropia…
- Conditions
- Intermittent Exotropia, Myopia Overcorrection, Over-minus Therapy, Myopia Progression
- Trial name
- NCT03952702
- Testing
- Myopic overcorrection
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ege University
Large Angle Exotropia
True Muscle Transplantation Surgery Versus Augmented Semi Hang Back Recession in Large Angle Exotropia: Evaluation of Efficacy and Lateral Gaze Incomitance
This a randomized clinical trial comparing True muscle transplantation surgery versus Augmented Semi hang back recession for treatment of large angle exotropia
- Trial name
- NCT07784842
- Testing
- True Muscle Transplantation Surgery, Augmented Semi hang back Recession
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Hassnaa Mohamed Abdelhameed Ahmed
Convergence Insufficiency Intermittent Exotropia (CI-IXT)
S-BLR Versus C-BLR for CI-IXT in Children
This is a multi-center, randomized single-blind controlled trial to compare the effectiveness of S-BLR with C-BLR for the treatment of CI-IXT in children.
- Trial name
- SCCIXT (NCT04064112)
- Testing
- S-BLR, C-BLR
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chen Zhao
Exotropia
Intermittent Exotropia in Egyptian Population
Strabismus is one of the most frequent ocular problems among developmentally normal children. The prevalence of strabismus varies among different regions, ranging from 0.06% in Japan to 5.65% in China.
- Trial name
- NCT06312865
- Testing
- Ophthalmic exam
- Volunteers
- 600 people
- Sponsor
- Assiut University
Intermittent Exotropia
Visual Perceptual Learning Based Digital Therapeutics for Stereopsis in Intermittent Exotropia
This study evaluates the efficacy and safety of visual perceptual learning for improving stereopsis in intermittent exotropia. Half of participants will receive visual perceptual training using the Nu.T.
- Trial name
- NCT06117813
- Testing
- Nu.T, No-Treatment Control
- Where
- 6 sites in South Korea
- Volunteers
- 54 people
- Sponsor
- Nunaps Inc