Clinical trials: Diversity, open to volunteers
Non Small Cell Lung Cancer
Assess Diversity of Gut Microbiome in Met NSCLC in Correlation to Tx & Adverse Effects
This is a pilot study collecting data on the diversity and composition of gut microbiomes in subjects with advanced/metastatic Non-Small Cell Lung Cancer (NSCLC) while receiving treatment for NSCLC.
- Trial name
- NCT06221800
- Testing
- Microbiome
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of California, Irvine
Pregnancy
Ghana MHL Project, Tamale
This study is designed to test a nutrition education program that focuses on local foods in northern Ghana. The goal is to help pregnant women eat a wider variety of foods, increase their intake of protein, energy, and iron-rich…
- Trial name
- NCT06898346
- Testing
- Nutrition Education
- Where
- Ghana
- Volunteers
- 250 people
- Sponsor
- Yale University
Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure
Real-world Effectiveness and Safety of Savagen (Sacubitril/Valsartan) in Malaysian HFrEF Patients
This multicentre, prospective, single-arm cohort study will evaluate the real-world effectiveness and safety of Savagen, an NPRA-approved generic sacubitril/valsartan, in Malaysian adults aged 18 to 70 years with heart failure…
- Trial name
- NCT07907640
- Testing
- Savagen (sacubitril/valsartan)
- Where
- 2 sites in Malaysia
- Volunteers
- 80 people
- Sponsor
- Sunway University
Transgender Persons
Research Participation With Transgender and Gender-Diverse Youth
Research has historically excluded the participation of transgender and gender-diverse people. The purpose of this research study is to find out about what goes into a transgender and gender-diverse youth's decision to…
- Trial name
- NCT05927350
- Testing
- Survey
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Virginia Commonwealth University
Obsessive-Compulsive Disorder
Project EMPOWER-OCD
This research study aims to adapt and evaluate the acceptability and effectiveness of Project EMPOWER-OCD for socioeconomically diverse caregivers of patients with OCD. Designed to reduce obstacles (e.g.
- Trial name
- NCT07158801
- Testing
- Project EMPOWER-OCD, Project CARE
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Gut Microbiota Diversity and Composition, Gut Microbiota Modulation
Effects of Barley and Kefir on Gut Microbiota in Physically Active Adults
The purpose of this randomized controlled clinical trial is to investigate whether a four-week dietary intervention consisting of a daily meal with barley and kefir can influence gut microbiota diversity and composition in…
- Conditions
- Gut Microbiota Diversity and Composition, Gut Microbiota Modulation, Probiotic, Prebiotic
- Trial name
- GUTS (NCT07864779)
- Testing
- Barley, Kefir
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western Norway University of Applied Sciences
Type 2 Diabetes
A Community Health Worker/Pharmacist Team to Improve Blood Sugars in Diabetes Care Using Continuous Glucose Monitoring
Continuous glucose monitoring (CGM) can help improve blood sugar management in type 2 diabetes. A sequential, multiple assignment, randomized trial will evaluate clinical pharmacists, community health workers, and telehealth in…
- Trial name
- TEAM-CGM (NCT05911256)
- Testing
- Pharmacist Only, Continuous Glucose Monitor (CGM), Community Health Worker (CHW)
- Where
- United States
- Volunteers
- 318 people
- Sponsor
- University of Massachusetts, Worcester
HIV Seropositivity, HIV Drug Resistance
Study of the Prevalence of Transmitted HIV-1 Resistance, Viral Diversity, and Cluster Identification in Patients at the Time of HIV-1 Diagnosis
The primary objective of the study is to determine the frequency of transmission of viruses carrying at least one antiretroviral resistance mutation in all participants newly diagnosed with HIV-1
- Conditions
- HIV Seropositivity, HIV Drug Resistance, HIV Infections
- Trial name
- PRINAVIH (NCT07146529)
- Volunteers
- 30,060 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Cardiovascular Diseases, Arrythmia
iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease
The Investigators will create a clinical database and a Biobank of stem cells derived from the blood of participants with cardiovascular disease.
- Conditions
- Cardiovascular Diseases, Arrythmia, Cardiomyopathies, Heart Failure
- Trial name
- INFERENCE (NCT06371937)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Breast Cancer, Lymph Node Metastasis
Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast Cancer
The purpose of this study is to determine how circulating tumor DNA (ctDNA), a sign of minimal residual disease (MRD), is detectable after surgery in patients with early HR+/HER2- breast cancer that has spread to 1-3 lymph nodes.
- Trial name
- NCT07025785
- Testing
- Circulating tumor DNA
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Smoking Cessation, Smoking Cessation Counseling Ability and Practice
Evaluating the Impact of CONNECT in a Multilingual Population
This study aims to broaden the reach of the lung cancer screening (LCS) CONNECT program (NCT04149249, NCT06213532), by developing a version of the program to be available to multilingual communities.
- Conditions
- Smoking Cessation, Smoking Cessation Counseling Ability and Practice, Smoking Cessation Counselling, Lung Cancer Screening
- Trial name
- CONNECT-ML (NCT07111936)
- Testing
- CONNECT Intervention for multilingual populations, Saliva Sample, Interview
- Where
- United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cancer Screening, Transgender
Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy
This study aims to quantify the rates of cervical cancer screening and endometrial sampling prior to gender-affirming hysterectomy, assess the need for these tests in TGD individuals, and explore patient-centered options for…
- Conditions
- Cancer Screening, Transgender, Gender Diverse Populations
- Trial name
- NCT07075731
- Testing
- No intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Transitioning Voice of Transgender and Gender Diverse People
Novel Delivery Method of Transgender Voice Modification Training Using a Mobile Application
The investigators hypothesize that the mobile application they developed for transgender and gender diverse individuals (TGGD) will be equivalent or better than traditional speech therapy in improving voice quality.
- Trial name
- NCT05815810
- Testing
- Attuned: A mobile application, In-Person Voice Modification Therapy
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Large B-Cell Lymphoma (LBCL), Multiple Myeloma (MM)
Restrictive Versus Standard Antibiotic Treatment During CAR-T Therapy
The purpose of the CARMic study is to investigate whether a restrictive, microbiome-sparing antibiotic strategy can better preserve the gut microbiota in patients undergoing chimeric antigen receptor T-cell (CAR-T) therapy…
- Conditions
- Large B-Cell Lymphoma (LBCL), Multiple Myeloma (MM), Gut Microbiota
- Trial name
- CARMic (NCT07842198)
- Testing
- ceftazidime, ciprofloxacin, Standard-of-Care Antibiotic Strategy
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Zealand University Hospital
Prostate Cancer
The BALANCE Study: BlAck and Mixed Men's Lived Experience With Prostate cANCEr-Diversity in Prostate Cancer PROMS Study
The BALANCE study is a prospective Patient Reported Outcomes Measures (PROMs) study developed to look at the quality of life (QoL) of patients diagnosed with prostate cancer (PCa) in communities underrepresented in research…
- Trial name
- BALANCE (NCT07529418)
- Testing
- Patient Reported Outcome Measurements (PROMs)
- Where
- Netherlands
- Volunteers
- 800 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Healthy, Exercise-Induced Lactic Acidemia
Microbiome Sampling During Endurance Exercise
The small intestine and feces of subjects undergoing endurance exercise will be sampled to examine their microbiome composition
- Trial name
- NCT06903806
- Testing
- Treadmill Exercise, Cooling Gloves, Microbiome Capsule
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Racially/Ethnically Diverse Families From Urban Settings
Multi-level Predictors of Structural Racism and Discrimination and Associations With Health and Well-being Across the Life Course in Diverse Families
Minoritized populations face mutually reinforcing levels of structural disadvantage that contribute to poor health. Despite recognition that social and economic stratification, environmental conditions, and policy are critical…
- Trial name
- NCT05744973
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- 631 people
- Sponsor
- University of Colorado, Denver
Cancer, Biomarker Discovery and Validation
Biomarkers for Cancer Treatment
Circulating biomarkers, such as miRNAs and proteomics, undergo identifiable and measurable changes during and following treatment for cancer, compared to pre-treatment baseline.
- Trial name
- NCT07803289
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Cervical Cancer Screening
The Use of a Novel Vaginal Speculum for Cervical Cancer Screening in Sunrise Community Health Patients
The specific aim of this research is to determine if the Bouquet Speculum TM , compared to the existing 2-bladed vaginal speculum, provides better visualization of the cervix, is easier for the provider to use and is more…
- Trial name
- NCT06496295
- Testing
- Vaginal Speculum Exam
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Elderly Small Eater
Loss of Autonomy in the Elderly: Relationships Between Gut Microbiota Diversity, Nutrition and Cognitive and Sensory-motor Disturbances in "Small Eaters" and "Non Small Eaters"
Older adults currently make up 25% of the population in France, and future health expenditures will be largely related to the consequences of aging.
- Trial name
- ALMICO (NCT05449119)
- Testing
- Fecal and blood sampling and collection of nutritional, cognitive and sensorimotor data, Body Mass Index (BMI), 24-hour food and beverage record
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire Dijon