Clinical trials: Diverticular Diseases
Diverticulitis, Acute Diverticulitis
Randomized Multicentric Trial to Evaluate a Free Diet With a Progressive Diet in the Treatment of Acute Diverticulitis (DIVERDIET)
Phase III trial is designed to demonstrate the non-inferiority of a free diet versus a progressive diet in the treatment of acute diverticulitis (AD) without complications.
- Conditions
- Diverticulitis, Acute Diverticulitis, Diverticulitis, Colonic, Uncomplicated Diverticular Disease
- Trial name
- NCT03496090
- Testing
- Free diet, Progressive diet
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Hospital General Universitario Reina Sofía de Murcia
Diverticulosis, Colonic
Mechanistic Randomized Controlled Trial (RCT) of Mesalazine in Symptomatic Diverticular Disease
Diverticulosis (bulges in the bowel wall) affects two third of the elderly population in the UK. Diverticular disease and its complications are responsible for 68000 hospital admissions and 2000 deaths per year.
- Trial name
- NCT00663247
- Testing
- Mesalazine
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
Diverticulitis, Colon Polyps
Early Post-Op Recovery After Partial Large Bowel Resection
The purpose of this trial is to gather information on the postoperative recovery time and hospital length of stay experienced by patients having laparoscopic surgeries.
- Conditions
- Diverticulitis, Colon Polyps, Colorectal Cancer
- Trial name
- NCT00492193
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- University Hospitals Cleveland Medical Center
Acute Cholecystitis, Colorectal Cancer
Safety and Feasibility of ActivSightTM in Human
ActivSightTM combines an innovative form factor and proprietary software to deliver precise, objective, real-time visualization of blood flow and tissue perfusion intraoperatively for laparoscope-based surgery.
- Conditions
- Acute Cholecystitis, Colorectal Cancer, Diverticulitis, Colonic, Obesity, Morbid
- Trial name
- NCT04633512
- Testing
- ActivSight
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Diverticulitis, Diverticulitis of Sigmoid
Clinical Trial With MBK-01, Intestinal Microbiota Capsules, for the Treatment of Patients With Recurrent Diverticulitis
Patients with diverticulitis experience a prolonged course of the disease and report a variety of physical, psychological and social symptoms, which highly impacts in their quality of life.
- Trial name
- NCT06687382
- Testing
- MBK-01
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Mikrobiomik Healthcare Company S.L.
Diverticular Disease of the Colon
Mesalazine and/or Lactobacillus Casei in the Diverticular Disease of the Colon
This is a multi-centre, randomised, double blind, double-dummy, parallel groups, placebo-controlled trial was conducted in a population of patients suffering from symptomatic uncomplicated diverticular disease in order to…
- Trial name
- NCT01534754
- Testing
- Mesalazine plus Lactobacillus casei, Mesalazine 800 mg, Lactobacillus casei
- Where
- 14 sites in Italy
- Volunteers
- 250 people
- Sponsor
- Hospital Cristo Re
Zenker Diverticulum
Endoscopic Treatment of Zenker's Diverticulum (ZENKTUN)
Prospective comparative observational study in numerous reference centers in France, comparing Tunnelization (Z-POEM) versus Non-Tunnelization Techniques according to the usual practices.
- Trial name
- NCT06594718
- Testing
- Endoscopic diverticulotomy with Z-POEM, Endoscopic diverticulotomy using a non-tunnelization technique
- Volunteers
- 128 people
- Sponsor
- Société Française d'Endoscopie Digestive
Diverticulum, Colon, Colorectal Neoplasms
Data Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis
The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing™ device in routine clinical practice at a single center.
- Conditions
- Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative
- Trial name
- RETROPRESS (NCT01301417)
- Testing
- ColonRing™
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- novoGI
Colonic Diverticula
Predictive Value of DICA in the Diverticular Disease of the Colon
The Diverticular Inflammation and Complication Assessment (DICA) is an endoscopic classification for diverticulosis and diverticular disease of the colon.
- Trial name
- NCT02758860
- Testing
- Colonoscopy
- Where
- 45 sites in Brazil, Italy and 5 more
- Volunteers
- 2,215 people
- Sponsor
- University of Roma La Sapienza
Rectal Cancer, Ulcerative Colitis
Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses
The primary purpose of this prospective, randomized multicenter center study is to evaluate and compare the outcomes of colorectal, coloanal and ileoanal anastomoses reinforced with a bioabsorbable staple line reinforcement…
- Conditions
- Rectal Cancer, Ulcerative Colitis, Familial Adenomatous Polyposis, Diverticulitis
- Trial name
- NCT00663819
- Testing
- GORE SEAMGUARD® Bioabsorbable Staple Line Reinforcement, Staple line without reinforcement
- Where
- 16 sites in United States
- Volunteers
- 258 people
- Sponsor
- W.L.Gore & Associates
Diverticular Disease of Left Side of Colon
Quality of Life (QOL) After Elective Sigmoidectomy for Diverticular Diseases (DIVERTI)
Acute diverticulitis of the left colon is among the most common abdominal disorders. To date, both conservative therapy in uncomplicated stages and emergency surgery in perforated disease with peritonitis are consensual.
- Trial name
- DIVERTI-QDV (NCT04730765)
- Testing
- left elective colectomy (Surgical Experimental Group), antibiotic therapy (medical Control Group)
- Volunteers
- 220 people
- Sponsor
- University Hospital, Caen
Anastomotic Leak, Colorectal Cancer
Anastomotic Leakage After Colorectal Surgery.
Anastomotic leakage (AL) is a severe complication after colorectal surgery, with incidence rates of 2-30%. This prospective, single-center observational cohort study aims to identify and quantify independent risk factors for AL…
- Conditions
- Anastomotic Leak, Colorectal Cancer, Diverticulitis
- Trial name
- AL (NCT07144683)
- Testing
- Patients Undergoing Colorectal Resection with Anastomosis
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Complications of Surgical Procedures, Surgical Site Infection
Quick Skin Sealant in Closure of Surgical Wound After Laparoscopic Surgery
The purpose of this study is to evaluate the short-term effect of sealant-assisted skin closure in prevention of surgical site infection after laparoscopic surgery.
- Conditions
- Complications of Surgical Procedures, Surgical Site Infection, Gastric Cancer, Colorectal Cancer
- Trial name
- NCT02426762
- Testing
- Laparoscopic surgery, Skin sealant
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Diverticulosis, Colonic, Abdominal Adhesion
Prior Abdominal Surgery: A Potential Risk Factor for Colonic Diverticulosis or Diverticulitis
Background \& Aims: Abnormal colonic pressure profiles have been associated with an increased risk of colonic diverticulosis. A surgical history is a known risk factor for abdominal adhesions, and these may lead to increased…
- Conditions
- Diverticulosis, Colonic, Abdominal Adhesion, Diverticulitis
- Trial name
- NCT05384925
- Testing
- comparison
- Where
- Israel
- Volunteers
- 359 people
- Sponsor
- Assaf-Harofeh Medical Center
Diverticulitis
Effect of Gum Arabic on Gastrointestinal Transit and Permeability
The study aims to determine the effect of gum arabic on gut bacteria and GI function.
- Trial name
- NCT03742076
- Testing
- High-dose prebiotic, Low-dose prebiotic
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic