Clinical trials: Diverticulitis
Surgery, Pancreatitis
Active Versus Non Active Drainage for the Treatment of Infected Intra-abdominal Collection
The Percutaneous drainage of symptomatic intra-abdominal collection (primary or secondary to surgery)is the treatment of choice in the absence of peritonitis signs.
- Conditions
- Surgery, Pancreatitis, Diverticulitis, Appendicitis
- Trial name
- NCT01513421
- Testing
- Percutaneous drainage of intra-abdominal collection
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Diverticulitis
Prevention of Recurrence of Diverticulitis
The purpose of this study is to determine whether SPD476 is effective in reducing recurrence of diverticulitis.
- Trial name
- PREVENT1 (NCT00545740)
- Testing
- SPD476 (1.2g), SPD476 (2.4 g), SPD476 (4.8 g)
- Where
- 121 sites in United States, Argentina and 9 more
- Volunteers
- 590 people
- Sponsor
- Shire
Colon Cancer, Inflammatory Bowel Diseases
Functional Restoration After Abdominal and Pelvic Laparoscopic Surgery: Effect of Perioperative Intravenous Lidocaine
This is a blinded randomized controlled trial in patients undergoing laparoscopic colon surgery. The aim of this study is to assess whether perioperative intravenous lidocaine has an impact on the early post operative physical…
- Conditions
- Colon Cancer, Inflammatory Bowel Diseases, Diverticulitis
- Trial name
- NCT00982618
- Testing
- Lidocaine, Epidural Block, PCA Morphine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Surgery, Diverticulitis
Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation
The purpose of this multi-center randomized trial is to identify any differences in the complication rates of patients undergoing Hartmann's (end colostomy) versus Primary Anastomosis (with defunctioning ileostomy) for left-sided…
- Conditions
- Surgery, Diverticulitis, Neoplasms, Postoperative Complications
- Trial name
- ColonPerfRCT (NCT01233713)
- Testing
- Hartmann's operation, Primary anastomosis
- Where
- 4 sites in Switzerland
- Volunteers
- 62 people
- Sponsor
- University of Zurich
Rectal Neoplasms, Colon Neoplasms
Fluorescent Evaluation of Colorectal Anastamoses
Bowel removal is indicated for various types of colon and rectal disease, including colon cancer, rectal cancer, diverticulitis, and inflammatory bowel disease among others.
- Conditions
- Rectal Neoplasms, Colon Neoplasms, Diverticulitis
- Trial name
- NCT01424293
- Testing
- Indocyanine Green, The SPY® Intraoperative Imaging System
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Maimonides Medical Center
Acute Uncomplicated Diverticulitis
APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis)
The goal of this clinical trial is to determine whether antibiotics improve recovery from acute uncomplicated diverticulitis (AUD) in racially and ethnically diverse United States clinical practice.
- Trial name
- NCT07492134
- Testing
- Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet, Metronidazole, Cefuroxime
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Lung Transplant Recipients, Diverticulitis
Epidemiology of Diverticulitis in Lung Transplant Recipients
The purpose of this study is to assess incidence, treatment modalities and outcome of complicated and uncomplicated diverticulitis in highly immunosuppressed lung transplant recipients (LTRs) in order to establish improved…
- Trial name
- NCT02132078
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Colonic Diverticulitis, Colorectal Cancer
The Diverticulitis Study
Acute colonic diverticulitis is when a part of the colon gets swollen and inflamed. The diagnosis is based on a CT scan, which can show thickening of the colonic walls and infiltration of the diverticula.
- Conditions
- Colonic Diverticulitis, Colorectal Cancer, Acute Diverticulitis
- Trial name
- NCT06023004
- Where
- 5 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Fecal Calprotectin Collection Protocol
The primary objective is to obtain stool samples from subjects diagnosed with , and displaying signs and/or symptoms of IBD and/or IBS will be evaluated in this study.
- Conditions
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Ulcerative Colitis, Crohn Disease
- Trial name
- CALFE (NCT03143517)
- Testing
- Stool collection
- Where
- 13 sites in United States
- Volunteers
- 240 people
- Sponsor
- DiaSorin Inc.
Colon Cancer, Upper Rectum Cancer
Informativeness to Digital Rectal Examination
Digital rectal examination is an act clinically performed daily by physicians and surgeons. It remains the key diagnostic test and directs the therapeutic management of cancer of the lower and middle rectum.
- Conditions
- Colon Cancer, Upper Rectum Cancer, Diverticulitis, Rectal Bleeding
- Trial name
- RIFIONA (NCT01727388)
- Testing
- lateral decubitus, supine decubitus
- Where
- 2 sites in France
- Volunteers
- 320 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Diverticulitis of Sigmoid
Quality of Life in Acute Complicated and Chronic Recurrent Left-sided Diverticulitis
Patients presenting in hospital with symptoms of acute diverticulitis. Acute inflammation of the left-sided colon is confirmed with CT scan or ultrasound in experienced centers and diagnosis is defined according to the…
- Trial name
- DATE (NCT05942833)
- Testing
- Sigmoid resection
- Where
- 4 sites in Austria, Germany
- Volunteers
- 136 people
- Sponsor
- Kepler University Hospital
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Diverticular Disease of Colon, Colostomy Complication
Comparing Hartmann's Procedure and Primary Resection With Anastomosis in Hinchey III-IV Diverticulitis: Focus on Ostomy Closure and Long-Term Outcomes
Brief Summary This multicenter study compares the effectiveness of primary anastomosis with diverting loop ileostomy to Hartmann's procedure for managing perforated sigmoid diverticulitis in stable patients.
- Conditions
- Diverticular Disease of Colon, Colostomy Complication, Colostomy - Stoma
- Trial name
- ARES (NCT06794905)
- Volunteers
- 578 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Peritonitis Caused by Perforated Left-sided Colon Diverticulitis
Hartmann vs R/A in Peritonitis by Perforated Diverticulitis
This prospective randomized trial is to prove the equivalence of primary sigmoid resection with end colostomy(Hartmann)(GROUP A) and primary sigmoid resection and immediate anastomosis with diverting stoma (GROUP B)with regard to…
- Trial name
- NCT01239927
- Testing
- Primary sigmoid resection with end colostomy (Hartmann), Primary sigmoid resection and immediate anastomosis with diverting stoma (PRA)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Diverticulitis
Effect of Gum Arabic on Gastrointestinal Transit and Permeability
The study aims to determine the effect of gum arabic on gut bacteria and GI function.
- Trial name
- NCT03742076
- Testing
- High-dose prebiotic, Low-dose prebiotic
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic