Clinical trials: Diverticulosis
Sigmoid Cancer, Sigmoid Diverticulosis
Comparison of Quality of Life and Functionnal Resultats After Sigmodectomy Between Diverticulitis and Cancer
The aim of this present study is to compare functional results and quality of life after sigmoidectomy for diverticulitis and sigmoid cancer.
- Trial name
- SIG-QOL (NCT04729283)
- Testing
- Sigmoidectomy
- Where
- 4 sites in France
- Volunteers
- 94 people
- Sponsor
- Nantes University Hospital
Colonic Diverticula, Angiodysplasia
Study of Hemospray for Lower Gastrointestinal Hemorrhage
This study is to evaluate the performance of Hemospray for the teatment of nonvariceal lower gastrointestinal bleeding.
- Conditions
- Colonic Diverticula, Angiodysplasia, Colonic Polyp
- Trial name
- NCT02099435
- Testing
- Hemospray
- Where
- 4 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Cook Group Incorporated
Diverticulitis, Diverticulitis Colon
Management and Evolution of Acute Diverticulitis With Pericolic Free Gas
The severity of diverticulitis is usually graded with the use of modified Hinchey Criteria. However, there is a condition often seen in the CT scan that is not included in this classification itself; 1-2 pericolic bubbles but no…
- Conditions
- Diverticulitis, Diverticulitis Colon, Diverticulitis; Perforation, Bowel, Diverticulitis of Sigmoid
- Trial name
- ADiFas (NCT04311385)
- Testing
- CT imaging
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital Central de la Defensa Gómez Ulla
Diverticulitis, Colonic, Therapy
Probiotic After Acute Colonic Diverticulitis
The goal of this observational study is to assess the efficacy and safety of the probiotic Escherichia coli Nissle 1917 (EcN®, Ca.Di.Group S.p.A) in the treatment of symptomatic patients after an episode of both complicated and…
- Trial name
- NCT06040515
- Testing
- Probiotic Formula
- Where
- 12 sites in Italy
- Volunteers
- 145 people
- Sponsor
- Erasmo Spaziani
Simple Diverticular Disease
Randomized Clinical Trial for the Uncomplicated Diverticulitis in Right Colon
The aim of the present study was to evaluate whether antibiotics is mandatory for the treatment of acute uncomplicated right-sided diverticulitis.
- Trial name
- NCT02314013
- Testing
- Cephalosporin + Metronidazole
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Dongtan Sacred Heart Hospital
Uncomplicated Diverticular Disease
Outpatient Treatment of Uncomplicated Diverticulitis With Either Antibiotic or Nonantibiotic Treatment
Uncomplicated sigmoid diverticulitis is a common disease in Western countries. Traditional management includes inpatient administration of either oral or intravenous antibiotics with resumption of oral intake as symptoms improve.
- Trial name
- MUD (NCT03146091)
- Testing
- Nonantibiotic treatment of uncomplicated diverticulitis, Antibiotic treatment of uncomplicated diverticulitis
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Jewish General Hospital
Diverticular Disease of Colon
Molecular and Microbiota Signatures Underlying Colonic Diverticular Disease
The pathogenesis of diverticular disease is likely multifactorial in origin. This project aims to study the involvement of environmental factors in the pathophysiology of diverticular disease, the underlying molecular mechanisms…
- Trial name
- GR-Barbaro (NCT06764550)
- Testing
- This is an observational study, participants are not assigned an intervention as part of the study.
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Colo-rectal Cancer, Colo-rectal Surgery
Post Operative Hospital at Home After Colorectal Surgery
The goal of this feasibility study is to investigate whether a virtual Hospital at Home is safe and possible for patients undergoing planned minimally invasive colorectal surgery.
- Conditions
- Colo-rectal Cancer, Colo-rectal Surgery, Colocolic and Ileocolic Anastomosis, Colon and/or Rectal Resection With Anastomosis for Cancer
- Trial name
- POPHaH (NCT07113717)
- Testing
- virtual Hospital at Home
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Nordsjaellands Hospital
Diverticulitis, Colonic
Unexpected Diagnosis in Right Lower Quadrant Pain: Right Colon Diverticulitis
BACKGROUND: Acute right lower quadrant pain is a common symptom in emergency departments. The most common etiology is thought to be acute appendicitis. Other etiologies may be overlooked.
- Trial name
- NCT06153030
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Diverticular Disease, Symptomatic Uncomplicated Diverticular Disease
Lactoferrin for the Treatment of Symptomatic Uncomplicated Diverticular Disease
Diverticular disease is a chronic pathology, characterized by recurrent abdominal symptoms and a high social impact, with a high prevalence in developed countries, especially among the elderly.
- Trial name
- SUDDENLY (NCT03490279)
- Testing
- Lactoferrin CRX
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Colorectal Cancer, Colorectal Anastomosis
Single-Stapled Technique for Colorectal Anastomosis
The goal of this observational multicenter study is to evaluate the safety and feasibility of a single-stapled technique (SST) for colorectal anastomosis and to explore whether this technique is associated with a reduced rate of…
- Conditions
- Colorectal Cancer, Colorectal Anastomosis, Anastomotic Leakage, Diverticular Disease of Left Side of Colon
- Trial name
- SST (NCT07417358)
- Testing
- Single-stapled colorectal anastomosis, Double-stapled colorectal anastomosis
- Where
- 5 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Diverticular Disease of Colon, Acute Diverticulitis
Analysis of the Role of the Microbiota in Diverticular Disease
A single-center, prospective observational cohort study conducted at the University Hospital of Navarra. The primary objective is to expand knowledge of diverticular disease and its pathological variants, as well as the influence…
- Conditions
- Diverticular Disease of Colon, Acute Diverticulitis, Gut Microbiota
- Trial name
- NCT07681505
- Where
- Spain
- Volunteers
- 285 people
- Sponsor
- Hospital of Navarra
Colorectal Cancer, Diverticular Disease
Precision Pain Management for Major Abdominal Surgery in Colorectal Surgery
The primary objectives of this study are to evaluate the potential for preoperative pharmacogenomics (PGx) testing to positively influence postoperative opioid use through visual analog scale (VAS) guided administration of…
- Conditions
- Colorectal Cancer, Diverticular Disease, Crohn Disease, Ulcerative Colitis
- Trial name
- PPaM (NCT03455751)
- Testing
- PGx-guided post-operative pain management
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Cleveland Clinic
Colon Cancer, Diverticulum, Colon
ERAS Lazio Network Clinical Registry
Enhanced recovery after surgery (ERAS) protocols are programs aiming to implement patients recovery following surgical procedures developed about 25 years ago.
- Trial name
- ENeRgy (NCT03353311)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- PERSIANI ROBERTO
Diverticular Disease, Diverticulitis
Confocal Laser Endomicrospy in Colonic Diverticular Disease
Confocal laser endomicroscopy detects inflammatory markers undetectable during high definition endoscopy. The investigators aimed to evaluate the role of peridiverticular and colonic mucosa inflammation in the prediction of the…
- Conditions
- Diverticular Disease, Diverticulitis, Diverticula
- Trial name
- NCT04173182
- Testing
- Probe-based confocal laser endomicroscopy evaluation
- Where
- Ecuador
- Volunteers
- 63 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Diverticulosis
Evaluate the Safety and Diagnostic Advantages of Tilt Down Verses Standard Horizontal Colonoscopy Positioning
A tortuous sigmoid colon makes colonoscopy difficult. The purpose of this study was to systematically evaluate the diagnostic utility and incidence of adverse events in women using standard horizontal compared to lateral tilt…
- Trial name
- CTDTTIE (NCT01815671)
- Testing
- colonoscopy in the lateral horizontal position
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Specialists in Gastroenterology, LLC
Zenker Diverticulum, Minimally Invasive Surgical Procedures
Minimally Invasive Endoscopic Treatment of Zenker's Diverticulum Comparing LigaSureTM vs SB-Knife.
The main purpose of this trial is to evaluate two devices used in the treatment of Zenker Diverticulum using flexible endoscopy (LigaSure and SB-knife).
- Conditions
- Zenker Diverticulum, Minimally Invasive Surgical Procedures, Endoscopy
- Trial name
- NCT04660214
- Testing
- septotomy
- Where
- Spain
- Volunteers
- 85 people
- Sponsor
- Hospital del Rio Hortega
Complications of Surgical Procedures, Surgical Site Infection
Quick Skin Sealant in Closure of Surgical Wound After Laparoscopic Surgery
The purpose of this study is to evaluate the short-term effect of sealant-assisted skin closure in prevention of surgical site infection after laparoscopic surgery.
- Conditions
- Complications of Surgical Procedures, Surgical Site Infection, Gastric Cancer, Colorectal Cancer
- Trial name
- NCT02426762
- Testing
- Laparoscopic surgery, Skin sealant
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Diverticular Diseases
Effect of Nutritional Counseling and Mediterranean Diet on Patients With Diverticular Disease
Diverticular Disease (DD) is a frequent condition in Western populations and may be associated with complications including bleeding, perforation, acute diverticulitis, and colon strictures.
- Trial name
- Nutri-DICA (NCT06797739)
- Testing
- Nutritional counselling, Diet
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Regione del Veneto - AULSS n. 7 Pedemontana
Intubation;Difficult
If Different Types of Periampullary Diverticula Affect ERCP Cannulation?
To study the influence of different types of periampullary diverticulum(PAD) on ERCP difficult cannulation and postoperative complications.
- Trial name
- NCT03556072
- Testing
- Routine ERCP
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province