Clinical trials: Diverticulosis
Colonic Diverticuar Disease, Defecatory Functions
Effects of Inferior Mesenteric Artery Preservation in Laparoscopic Colorectal Resection for Diverticular Disease.
This is a prospective randomized study aimed to verifying the short and long-term results of inferior mesenteric artery preservation following colorectal resection for diverticular disease
- Conditions
- Colonic Diverticuar Disease, Defecatory Functions, Fecal Incontinence, Constipation
- Trial name
- EIMAP (NCT06506552)
- Testing
- IMA preserving, IMA sectioning
- Volunteers
- 300 people
- Sponsor
- University of Roma La Sapienza
Diverticular Disease
Immunohistology in USDD and Correlation Between Bacterial Flora and Phlogosis
Diverticulosis of the colon is a frequent condition in adults in western countries and a significant number of patients experience clinical symptoms even when the diverticulosis is not complicated by diverticulitis.
- Trial name
- NCT02068482
- Testing
- Rifaximin
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Catholic University of the Sacred Heart
Simple Diverticular Disease
Evaluation of the Metabolome in Diverticular Disease
To evaluate the effect of the probiotic formulation VSL#3 on the metabolome and microbiota of diverticular disease, comparing it with the effects exerted by supplementation with fibers, by rifaximin and by mesalazine, and…
- Trial name
- NCT01831323
- Testing
- VSL#3, Rifaximin, Mesalazine
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- S.Eugenio Hospital
Colonic Diverticulosis
Mesalamine for Uncomplicated Diverticular Disease: a Randomized, Double-blind, Placebo-controlled Study
The purpose of this study is to determine whether mesalamine is effective in the treatment of uncomplicated diverticular disease by reducing the pain.
- Trial name
- NCT01627262
- Testing
- Mesalamine
- Where
- Germany
- Volunteers
- 123 people
- Sponsor
- Dr. Falk Pharma GmbH
Diverticulosis
Balloon Colonoscopy for Incomplete Colonoscopy
Patients with a prior incomplete colonoscopy will be enrolled in this study. Patients will be randomized to either an initial repeat attempt with a standard colonoscope or the single balloon enteroscope.
- Trial name
- NCT00935857
- Testing
- Single Balloon Colonoscopy, Standard Colonoscopy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Sexual Function Disturbances
Preservation of Inferior Mesenteric Artery Could Improve Sexual Function After Laparoscopic Colorectal Resection for Diverticular Disease
This study aims to evaluate whether IMA sparing may represent an advantage in terms of reduced incidence and severity of sexual dysfunctions after colorectal resections for diverticular disease (DD).
- Trial name
- IMAPSEX (NCT04752241)
- Testing
- Inferior Mesenteric Artery Preservation, Inferior Mesenteric Artery Ligation
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Roma La Sapienza
Periampullary Diverticula
Effect of EPBD in ERCP on the Prognosis of Patients With Choledocholithiasis Complicated With Duodenal Papillary Diverticula
The investigators hypothesized that nipple balloon dilatation could make ERCP more successful and reduce postoperative complications and mortality. So the investigators design this experiment on this assumption.
- Trial name
- EPBD (NCT04254887)
- Testing
- EPBD, EST
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Renmin Hospital of Wuhan University
Diverticulitis, Diverticulitis of Sigmoid
Clinical Trial With MBK-01, Intestinal Microbiota Capsules, for the Treatment of Patients With Recurrent Diverticulitis
Patients with diverticulitis experience a prolonged course of the disease and report a variety of physical, psychological and social symptoms, which highly impacts in their quality of life.
- Trial name
- NCT06687382
- Testing
- MBK-01
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Mikrobiomik Healthcare Company S.L.
Diverticulitis, Uncomplicated Diverticular Disease
FMT in Uncomplicated Diverticulitis
Fecal Microbiota Transplantation (FMT) is an established treatment for Clostridium difficile (C. diff) infection refractory to medical management. As C.
- Trial name
- NCT05373784
- Testing
- Fecal Microbiota Transplantation (FMT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Justin Maykel
Colon Neoplasms, Rectal Neoplasms
The Role of Indocyanine Green (ICG) Fluorescence Imaging on Anastomotic Leak in Robotic Colorectal Surgery
In colorectal surgery, anastomotic leak and its septic consequences still remain as the most concerning complications resulting in substantial morbidity and mortality.
- Conditions
- Colon Neoplasms, Rectal Neoplasms, Inflammatory Bowel Disease, Diverticular Disease
- Trial name
- NCT02598414
- Testing
- Near-infrared ICG fluorescence imaging, Traditional bowel anastomosis, FireFly™
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Acibadem University
Biliary Disease, Gallstone; Cholecystitis, Acute
Multicentric Point of Care UltraSound by Surgeons Trial
Acute gallbladder pathology and acute diverticulitis are common conditions met in emergency departments and comprise the bulk of admissions throughout general surgical calls.
- Conditions
- Biliary Disease, Gallstone; Cholecystitis, Acute, Diverticulitis, Colonic, Abscess Pelvic
- Trial name
- POCUSS (NCT02682368)
- Testing
- Point of Care Ultrasound by Surgeons (POCUSS), Radiology report, Surgery-Intra-operative findings
- Where
- 5 sites in Ireland, Italy and 2 more
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Connolly Hospital Blanchardstown
Sigmoid Diverticulosis, Colorectal Surgery
Impact of Socioeconomic and Territorial Inequalities on Surgical Management of Sigmoid Diverticulitis
Sigmoid diverticulitis (SD) is a common pathology characterized by inflammation/infection of a diverticulum in the sigmoid colon.
- Trial name
- EDIVERTICULITE (NCT06200857)
- Where
- France
- Volunteers
- 6,800 people
- Sponsor
- University Hospital, Caen
Diverticulosis, Diverticulitis
Role Of Lactobacillus Reuteri DSM 17938 In The Non-Complicated Diverticular Disease
The aim of this study is to evaluate the effectiveness and the tolerability of the Lactobacillus reuteri in the control of the diverticular disease symptoms and in the prevention of acute diverticulitis episodes.
- Trial name
- ReDiCo (NCT01168154)
- Testing
- Lactobacillus Reuterii
- Where
- 2 sites in Italy
- Volunteers
- 160 people
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Zenker Diverticulum
A New Treatment for Zenker's Diverticulum-submucosal Tunneling Endoscopic Septum Division
Zenker's Diverticulum (ZD) is a sac-like outpouching of the lining of the esophageal wall at the upper esophagus. It is a rare disease typically seen in the middle-aged and older adults.
- Trial name
- STESD (NCT03125733)
- Testing
- Submucosal tunneling endoscopic septum division
- Where
- 2 sites in United States, China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Diverticulitis, Acute Diverticulitis
Randomized Multicentric Trial to Evaluate a Free Diet With a Progressive Diet in the Treatment of Acute Diverticulitis (DIVERDIET)
Phase III trial is designed to demonstrate the non-inferiority of a free diet versus a progressive diet in the treatment of acute diverticulitis (AD) without complications.
- Conditions
- Diverticulitis, Acute Diverticulitis, Diverticulitis, Colonic, Uncomplicated Diverticular Disease
- Trial name
- NCT03496090
- Testing
- Free diet, Progressive diet
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Hospital General Universitario Reina Sofía de Murcia
Diverticular Diseases, Diverticulitis
RObotic Versus LAparoscopic Colectomy for DIverticulitis.
Over the last decade there has been a growing interest toward the application of robotic approach for diverticular disease. The evidence available on the literature showed that robotic approach, compared to the laparoscopic…
- Trial name
- ROLADI (NCT05829343)
- Testing
- Laparoscopic Left colectomy, Robotic left colectomy
- Where
- Italy
- Volunteers
- 1,450 people
- Sponsor
- S.M. Misericordia Hospital
Colonic Diverticulitis, Colorectal Cancer
The Diverticulitis Study
Acute colonic diverticulitis is when a part of the colon gets swollen and inflamed. The diagnosis is based on a CT scan, which can show thickening of the colonic walls and infiltration of the diverticula.
- Conditions
- Colonic Diverticulitis, Colorectal Cancer, Acute Diverticulitis
- Trial name
- NCT06023004
- Where
- 5 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Colonic Neoplasms, Diverticulosis, Colonic
Interest of the Nefopam and PCA Morphine Combination for Postoperative Analgesia in Patients Undergoing Colon Surgery
This study analyses interest of iv nefopam in combination with paracetamol after major abdominal surgery because the effect of morphine-sparing is discussed when combined these agents.
- Trial name
- NEFOPAM (NCT03619538)
- Testing
- Nefopam, saline solution
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Diverticular Diseases, Gastro-Intestinal Disorder
Clostridium Butyricum CBM588® vs. Rifaximin for Symptomatic Uncomplicated Diverticular Disease (SUDD): A Real-World Retrospective Study
This retrospective, real-world, single-center clinical study aimed to evaluate the effectiveness of probiotic Clostridium butyricum CBM588® (Butirrisan®) versus Rifaximin in the management of Symptomatic Uncomplicated…
- Trial name
- NCT06852274
- Testing
- Clostridium butyricum CBM588® (Butirrisan®), Rifaximin 400 mg Oral Tablet
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Dr. Amjad Khan
Anastomotic Leak, Colorectal Cancer
The Prediction of Anastomotic Insufficiency Risk After Colorectal Surgery (PANIC) Study
The Prediction of Anastomotic Insufficiency risk after Colorectal surgery (PANIC) study aims to establish a machine-learning-based application that allows for accurate preoperative prediction of patients at risk for anastomotic…
- Conditions
- Anastomotic Leak, Colorectal Cancer, Diverticulosis, Crohn Disease
- Trial name
- NCT04985981
- Where
- 2 sites in Switzerland
- Volunteers
- 11,000 people
- Sponsor
- Michel Adamina, MD