Clinical trials: Diverticulum, Colon
Complications of Surgical Procedures, Surgical Site Infection
Quick Skin Sealant in Closure of Surgical Wound After Laparoscopic Surgery
The purpose of this study is to evaluate the short-term effect of sealant-assisted skin closure in prevention of surgical site infection after laparoscopic surgery.
- Conditions
- Complications of Surgical Procedures, Surgical Site Infection, Gastric Cancer, Colorectal Cancer
- Trial name
- NCT02426762
- Testing
- Laparoscopic surgery, Skin sealant
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Diverticular Disease of Colon, Colostomy - Stoma
ARES Trial: Approach to Resection and Evaluation in Severe Diverticulitis
This observational study was conducted across five surgical centers in Italy, including both academic and community hospitals, from January 2017 to December 2022.
- Conditions
- Diverticular Disease of Colon, Colostomy - Stoma, Loop Ileostomies
- Trial name
- ARES (NCT07094594)
- Where
- Italy
- Volunteers
- 578 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Diverticulosis, Colonic
L-glutamine Treatment in Patients With Diverticulosis
The purpose of the study is evaluate the safety and efficacy of L-glutamine as a treatment for patients with diverticulosis.
- Trial name
- NCT05106101
- Testing
- L-glutamine
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Emmaus Medical, Inc.
Outcome
Treatment in Right Colon Diverticulitis Patients
The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness.
- Trial name
- NCT04746326
- Testing
- Failure conservative treatment, Surgery, Conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Tepecik Training and Research Hospital
Diverticular Disease of Left Side of Colon
Quality of Life (QOL) After Elective Sigmoidectomy for Diverticular Diseases (DIVERTI)
Acute diverticulitis of the left colon is among the most common abdominal disorders. To date, both conservative therapy in uncomplicated stages and emergency surgery in perforated disease with peritonitis are consensual.
- Trial name
- DIVERTI-QDV (NCT04730765)
- Testing
- left elective colectomy (Surgical Experimental Group), antibiotic therapy (medical Control Group)
- Volunteers
- 220 people
- Sponsor
- University Hospital, Caen
Colorectal Cancer, Inflammatory Bowel Disease
Single-port Versus Conventional Laparoscopic Colorectal Surgery
Conventional multi-port laparoscopic surgery (CL) is now a standard approach to colorectal resections, due to it's short-term benefits over conventional open surgery.
- Conditions
- Colorectal Cancer, Inflammatory Bowel Disease, Benign Colorectal Neoplasm, Diverticular Disease
- Trial name
- NCT01626963
- Testing
- Single-port access surgery, Conventional Laparoscopic Access
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- North Tees and Hartlepool NHS Foundation Trust
Colon Neoplasms, Rectal Neoplasms
The Role of Indocyanine Green (ICG) Fluorescence Imaging on Anastomotic Leak in Robotic Colorectal Surgery
In colorectal surgery, anastomotic leak and its septic consequences still remain as the most concerning complications resulting in substantial morbidity and mortality.
- Conditions
- Colon Neoplasms, Rectal Neoplasms, Inflammatory Bowel Disease, Diverticular Disease
- Trial name
- NCT02598414
- Testing
- Near-infrared ICG fluorescence imaging, Traditional bowel anastomosis, FireFly™
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Acibadem University
Diverticulitis Colon, Quality of Life
Quality of Life and Surgery in Diverticular Disease
Diverticular disease is one of the most common diseases of the gastrointestinal tract in industrial countries. Prevalence and admission rate due to diverticular disease increases.
- Conditions
- Diverticulitis Colon, Quality of Life, Diverticular Disease of Left Side of Colon
- Trial name
- NCT05393609
- Testing
- Sigmoidectomy, Conservative
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Acute Complicated Diverticulitis, Colonic Diverticulitis
Management of Acute Complicated Diverticulitis: An Assessment of Current Practices
Acute complicated diverticulitis (ACD) is a frequent surgical emergency that can be life-threatening. It encompasses various clinical entities, including colonic perforations, abscesses (Hinchey II), fistulas, and purulent or…
- Trial name
- NCT07601958
- Where
- Belgium
- Volunteers
- 208 people
- Sponsor
- Jules Bordet Institute
Diverticulum, Colon, Diverticulitis
Registro Malattia Diverticolare (Registry of Diverticular Disease)
To determine the clinical characteristics and risk factors for the onset of diverticular disease and its complications in the Italian population.
- Trial name
- REMAD (NCT03325829)
- Volunteers
- 1,217 people
- Sponsor
- Gruppo Italiano Malattia Diverticolare
Diverticular Disease of Colon, Diverticulitis, Colonic
Evaluation of Laparoscopic Peritoneal Lavage for Perforated Diverticulitis: A National Registry - Based Study
The goal of this observational study is to study the emergency surgical treatment of diverticular disease in Sweden outside clinical trials.
- Conditions
- Diverticular Disease of Colon, Diverticulitis, Colonic, Peritonitis, Gastrointestinal Diseases
- Trial name
- NCT05893095
- Volunteers
- 52,863 people
- Sponsor
- Uppsala University Hospital
Neoplasm, Diverticular Disease
Peri-Operative Management of Patients Undergoing Laparoscopic Colorectal Surgery
The aim is to ascertain which method out of epidural, spinal or patient controlled analgesia (PCA) is the most appropriate in fluid optimised patients after laparoscopic colorectal surgery in terms of pain control, length of…
- Conditions
- Neoplasm, Diverticular Disease, Analgesia
- Trial name
- NCT00747292
- Testing
- epidural, PCA, Spinal
- Where
- United Kingdom
- Volunteers
- 99 people
- Sponsor
- Minimal Access Therapy Training Unit
Diverticular Disease
Prophylactic Elective Clipping of Colonic Diverticula
Diverticular bleeding is the most common cause of acute lower gastrointestinal bleeding (LGIB) in Western populations. Although self-limited in 85% of cases, some patients may require hospitalization with blood transfusion and…
- Trial name
- NCT02094456
- Testing
- Endoscopic clipping of diverticula, Follow-up colonoscopy
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- King's College Hospital NHS Trust
Diverticular Disease, Diverticulitis
Confocal Laser Endomicrospy in Colonic Diverticular Disease
Confocal laser endomicroscopy detects inflammatory markers undetectable during high definition endoscopy. The investigators aimed to evaluate the role of peridiverticular and colonic mucosa inflammation in the prediction of the…
- Conditions
- Diverticular Disease, Diverticulitis, Diverticula
- Trial name
- NCT04173182
- Testing
- Probe-based confocal laser endomicroscopy evaluation
- Where
- Ecuador
- Volunteers
- 63 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Diverticulosis, Colonic
Mechanistic Randomized Controlled Trial (RCT) of Mesalazine in Symptomatic Diverticular Disease
Diverticulosis (bulges in the bowel wall) affects two third of the elderly population in the UK. Diverticular disease and its complications are responsible for 68000 hospital admissions and 2000 deaths per year.
- Trial name
- NCT00663247
- Testing
- Mesalazine
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
Simple Diverticular Disease
Evaluation of the Metabolome in Diverticular Disease
To evaluate the effect of the probiotic formulation VSL#3 on the metabolome and microbiota of diverticular disease, comparing it with the effects exerted by supplementation with fibers, by rifaximin and by mesalazine, and…
- Trial name
- NCT01831323
- Testing
- VSL#3, Rifaximin, Mesalazine
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- S.Eugenio Hospital
Colectomy, Appendicitis
Colonic Resections in Patients With Suspected Appendicitis
Although many reports have been published on colonic resections in patients with suspected appendicitis and the diseases that cause the decision to resect the colon have been identified and their proper treatments have been…
- Trial name
- NCT00888888
- Testing
- Right hemicolectomy with or without primary anastomosis
- Where
- Chile
- Volunteers
- 87 people
- Sponsor
- Cirujanos la Serena
Anastomotic Leak, Colorectal Cancer
The Prediction of Anastomotic Insufficiency Risk After Colorectal Surgery (PANIC) Study
The Prediction of Anastomotic Insufficiency risk after Colorectal surgery (PANIC) study aims to establish a machine-learning-based application that allows for accurate preoperative prediction of patients at risk for anastomotic…
- Conditions
- Anastomotic Leak, Colorectal Cancer, Diverticulosis, Crohn Disease
- Trial name
- NCT04985981
- Where
- 2 sites in Switzerland
- Volunteers
- 11,000 people
- Sponsor
- Michel Adamina, MD
Diverticulosis, Colonic, Rectal Neoplasms
Concentration of Ertapenem in Colorectal Tissue
The purpose of this study is to determine the tissue kinetics of ertapenem in colonic tissue from three hours up to six hours (25% of dosing interval) after administration of ertapenem.
- Conditions
- Diverticulosis, Colonic, Rectal Neoplasms, Colonic Neoplasms
- Trial name
- NCT00535652
- Testing
- Ertapenem
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- University of Ulm
Colonic Diverticula, Angiodysplasia
Study of Hemospray for Lower Gastrointestinal Hemorrhage
This study is to evaluate the performance of Hemospray for the teatment of nonvariceal lower gastrointestinal bleeding.
- Conditions
- Colonic Diverticula, Angiodysplasia, Colonic Polyp
- Trial name
- NCT02099435
- Testing
- Hemospray
- Where
- 4 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Cook Group Incorporated