Clinical trials: Diving
Saturation Exposure, Decompression Injury
Inflammatory and Cerebrospinal Biochemical Markers in Blood During Prolonged Hyperbaric Exposure
Research hypothesis Prolonged hyperbaric exposure will affect the central nervous system Prolonged hyperbaric exposure will induce inflammatory changes Prolonged hyperbaric exposure will affect fluid regulation in the body…
- Trial name
- Mättnad2017 (NCT03192930)
- Testing
- Hyperbaric exposure
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Sahlgrenska University Hospital
Psychological Stresses
Recreational Diving Practice for Stress Management
Within the components of Scuba diving there are similarities with meditation and mindfulness techniques. Perceived stress is known to be diminished during meditation practice.
- Trial name
- DIVSTRESS (NCT03110705)
- Testing
- sport
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Decompression Sickness, Diving
A Descriptive Analysis of Diving Accidents Treated at the Hyperbaric Chamber of Nice Hospital Between 2014 and 2025
The study aims to describe and analyse the individual parameters of patients treated at the hyperbaric chamber of Nice University Hospital for suspected diving accidents.
- Trial name
- NCT07621354
- Testing
- medical care in a hyperbaric unit
- Volunteers
- 468 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Diving Barotrauma
Practice of Scuba Diving by as Many People as Possible: Effect of Medical Assessment to Provide a Suitable and Individualised Framework for Practice (Plongée Santé)
The study focuses on the practice of recreational scuba diving by people who have obtained medical advice for their practice in the hyperbaric and underwater medicine department of the Brest University Hospital.
- Trial name
- Healthy-diving (NCT06555666)
- Where
- France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Brest
Obesity and Overweight
A Combined Mindfulness-diving Protocol on Emotional Eating in Obese Patients: A Prospective Randomized Study
The goal of this clinical trial is to learn if a combined minfulness-diving program has an impact on emotional eating in adults with obesity.
- Trial name
- OBEDIVE (NCT06882200)
- Testing
- A combined mindfulness and therapeutic scuba-diving protocol, Control group regular follow up in primary care
- Where
- France
- Volunteers
- 63 people
- Sponsor
- BATHYSMED
Stress Disorder, Combat
Benefits of Diving Training on Recovery for Veterans Suffering of Chronic PTSD: an Exploratory Study
Patients suffering from Chronic Posttraumatic Stress Disorder (PTSD) have difficulties in executive cognition that hinder their quality of life and make it difficult to recovery and to reintegrate them socially and…
- Trial name
- cognidive (NCT03995992)
- Testing
- sport
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Institut de Recherche Biomedicale des Armees
Down Syndrome, Autonomic Dysfunction
Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome
Down syndrome (DS), the most common genetic cause of intellectual disability, is associated with widespread organ dysfunction, including abnormalities in the autonomic nervous system (ANS).
- Trial name
- DIVE (NCT07238465)
- Testing
- Cold Stress, Maximal Dynamic Exercise, Isometric Handgrip Exercise with Post-Exercise Muscle Ischemia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Chronic Disease, Arthritis
Deep Dive Randomized Control Trial
Compare two care management support program models on medical costs and utilization.
- Conditions
- Chronic Disease, Arthritis, Uterine Diseases, Spinal Diseases
- Trial name
- NCT00793260
- Testing
- Enhanced Support, Usual-Support
- Where
- United States
- Volunteers
- 174,120 people, healthy volunteers welcome
- Sponsor
- Health Dialog
Decompression Sickness, SCUBA Diving
High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation
The purpose of this study is to determine the impact of high intensity,anaerobic exercise, in the form of cycling, on SCUBA diving.
- Trial name
- NCT02064361
- Testing
- High intensity exercise
- Where
- 2 sites in United States, Croatia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Split
Healthy
Can Erythropoietin Protect the Cerebral Blood Flow and Oxygenation During Simulated Dive?
During facial cooling and especially during breath hold, can mammals - and also humans - elicit a so called dive reflex, causing bradycardia, peripheral vasoconstriction and centralization of blood flow to brain, lungs and heart…
- Trial name
- NCT00265486
- Testing
- Recombinant human Erythropoietin
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Decompression Sickness, Barotrauma
Health, Fitness, and Safety Knowledge as Determinants of Adverse Events in Recreational Divers in Poland
This cross-sectional online survey study assesses health status, physical fitness, and safety knowledge as potential determinants of diving-related adverse events among recreational divers in Poland.
- Conditions
- Decompression Sickness, Barotrauma, Recreational Diving
- Trial name
- DIVE-PL (NCT07855861)
- Testing
- Anonymous online questionnaire
- Where
- 2 sites in Poland
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Ptsd
Diving for Post Traumatic Stress Disorder (PTSD)
within the components of Scuba diving there are similarities with meditation and mindfulness techniques. PTSD and emotion dysregulation are known to be involved by meditation training This study evaluates the benefits of scuba…
- Trial name
- Dive-Hope (NCT03332290)
- Testing
- sport practice
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Marion Trousselard
Diving, Aquatic
Effect of Diving and Aquatic Exercises on Muscle Spasticity and Motor Function in Children With Spastic Cerebral Palsy
This study aims to evaluate the effect of diving and aquatic exercises on muscle spasticity and motor function in children with spastic cerebral palsy.
- Conditions
- Diving, Aquatic, Muscle Spasticity, Motor Function
- Trial name
- NCT06902168
- Testing
- Intensive swimming program
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Benha University
Healthy Volunteers
Effects of Levocetirizine and Hydroxyzine on Cognitive and Psychomotor Functioning During Simulated Diving
Antihistamines are commonly used and currently levocetirizine is most frequently prescribed in the Netherlands. They are commonly used by divers, to solve ear, nose and throat problems, especially to open tubal passage.
- Trial name
- NCT01496911
- Testing
- Levocetirizine, Hydroxyzine
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Hyperbaric, Diving Medicine
Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air
Primary objective: Assessment of venous gas emboli load post diving when breathing normobaric oxygen compared to air. Secondary objective: Assessment of fluid markers of central nervous system injury in blood post diving…
- Conditions
- Hyperbaric, Diving Medicine, Decompression Sickness, Central Nervous Injury
- Trial name
- NCT02468752
- Testing
- Oxygen, Air
- Where
- 2 sites in Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Oxygen Toxicity
Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 2)
The purpose of this study is to understand how ketogenic food products affect oxygen toxicity in undersea divers. Oxygen toxicity affecting the central nervous system, mainly the brain, is a result of breathing higher than normal…
- Trial name
- NCT05831228
- Testing
- Ketogenic food products
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Duke University
Glaucoma, Intraocular Pressure
Intraocular Pressure During Static Apnea
This prospective observational study evaluated changes in intraocular pressure (IOP) during dry static apnea (STA) in breath-hold divers.
- Conditions
- Glaucoma, Intraocular Pressure, Apnea
- Trial name
- NCT07604428
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Olomouc
Decompression Sickness, Endothelial Dysfunction
Exercise and Repetitive Diving
SCUBA diving frequently involves repetitive exposures over multiple days. The goal of this study was to see how exercise impacts microparticles (MPs), endothelial function, and venous gas emboli (VGE) over a series of dives.
- Conditions
- Decompression Sickness, Endothelial Dysfunction, Neutrophil Activation, Venous Gas Emboli
- Trial name
- NCT02118207
- Testing
- Aerobic running exercise
- Where
- 2 sites in United States, Croatia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Split
Injuries
Common Recreational Diving Practices: A Randomized Control Trial Using Pre-Dive Checklist
To evaluate the efficacy of using a pre-dive checklist to prevent the incidence of diving mishaps in recreational divers.
- Trial name
- Checklists (NCT01960738)
- Testing
- A pre-dive checklist
- Where
- 4 sites in United States, Cayman Islands and 1 more
- Volunteers
- 1,116 people, healthy volunteers welcome
- Sponsor
- Divers Alert Network
Post-traumatic Stress Disorder
Clinical Study About the Effects of Scuba Diving on Post Traumatic Stress Disorder (PTSD)
Post-traumatic stress disorder (PTSD) is a set of symptoms that can be developed as a result of exposure to a traumatic event or events that can range in prevalence from 25% to 75%.
- Trial name
- DIVE4NICE (NCT04343924)
- Testing
- Scuba diving activities, Virtual reality activities
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de Nice