Clinical trials: Docosahexaenoic Acid
Osteopenia, Sarcopenia
Olive Oil Polyphenols, Vitamin D, Docosahexaenoic Acid (DHA) and Locomotor Function (PolivD3)
The present project hypothesizes that the potential protective effect of olive oil relies on its polyphenols profile (quality and quantity) and that it may be synergistic to other food components.
- Trial name
- PolivD3 (NCT01828944)
- Testing
- olive oil
- Where
- 2 sites in France
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Lesieur
Esophageal Cancer
Trial of Enteral Nutrition Enriched With Eicosapentaenoic Acid (EPA) in Upper Gastrointestinal Cancer Surgery
This study aims to examine whether providing tube feeding with a formula enriched with omega-3 fats is better than traditional standard tube feeding in terms of preserving nutritional status, improving immune function and…
- Trial name
- NCT00790140
- Testing
- Prosure, Ensure Plus
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- University of Dublin, Trinity College
Levels of DHA in the Blood
The Effects of Study Products Containing Varying Quantities of Docosahexaenoic Acid (DHA)
The clinical trial will provide a milk-based drink with constant amounts of nutrients but differing amount of Docosahexaenoic Acid (DHA).
- Trial name
- NCT01174134
- Testing
- Nutritional beverage
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Sickle Cell Disease
Omega-3 Fatty Acids in Sickle Cell Disease
The purpose of this study is to determine the safety of a new formulation of the omega-3 fatty acids Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) and to assess whether it decreases inflammation and inflammatory pain…
- Trial name
- NCT02947100
- Testing
- SCD-Omegatex™
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Robin E. Miller
Previous Myocardial Infarction
Effect of Omega 3 Fatty Acids on Vascular Function
The mechanisms through which omega-3 fatty acids reduce adverse cardiac events remain uncertain. The aim of the study was to investigate the effect of omega-3 fatty acid supplementation on endothelial vasomotor function…
- Trial name
- NCT01888211
- Testing
- Omega 3 fatty acid supplementation, Olive Oil
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Major Depressive Disorder in Pregnancy
Open Trial Determining Antidepressant Effects of Omega-3 Supplementation During Pregnancy
The purpose of this study is to determine if omega-3 polyunsaturated fatty acids as a monotherapy have antidepressant effects during pregnancy.
- Trial name
- NCT03101527
- Testing
- Omega-3 PUFA supplementation
- Volunteers
- 3 people
- Sponsor
- William Coryell
Severe Sepsis, Organ Dysfunction Syndrome
Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients
The purpose of this study is to evaluate if enteral docosahexaenoic acid (DHA) administration attenuates the inflammatory cytokines and improve clinical outcomes in neonates who underwent cardiovascular surgery
- Trial name
- DHA-IRCO (NCT01049529)
- Testing
- Docosahexaenoic acid
- Where
- Mexico
- Volunteers
- 55 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Esophageal Atresia
Omega 3 Fatty Acid Treatment for Pediatric Musculoskeletal Health
This is a randomized clinical trial comparing Omegaven® treatment with standard of care (soybean-based lipid formulation, Intralipid®) on bone health outcomes in infants with esophageal atresia (EA) undergoing surgical repair at…
- Trial name
- NCT03127345
- Testing
- Omegaven, Intralipid
- Sponsor
- Boston Children's Hospital
Psychosis
NAPLS Omega-3 Fatty Acid Versus Placebo Study
The overall goal of the present study is to determine whether Omega-3 Fatty Acids potentially prevent onset of psychosis and improve clinical symptoms and functional outcome in youth and young adults at elevated clinical risk for…
- Trial name
- NCT01429454
- Testing
- Omega-3 Long Chain Fatty Acid
- Where
- 9 sites in United States, Canada
- Volunteers
- 127 people
- Sponsor
- University of California, San Diego
Acute Lymphoblastic Leukemia, Malnutrition
Effect of Enteral Docosahexaenoic Acid Administration in Children With Acute Lymphoblastic Leukemia
The purpose of this study is to evaluate if enteral docosahexaenoic acid (DHA) administration during the first three months of treatment reduces the deterioration of nutritional status, treatment toxicity and early mortality in…
- Trial name
- DHA-ALL (NCT01051154)
- Testing
- Docosahexaenoic acid (DHA)
- Where
- Mexico
- Volunteers
- 72 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Type 2 Diabetes, Insulin Sensitivity/Resistance
Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry "Bad Cholesterol" in the Blood
In this project, investigators explored the role of the particles that carry "bad cholesterol" in the blood (termed LDL) that are known to promote heart disease, in the promotion of type 2 diabetes (T2D) in humans.
- Conditions
- Type 2 Diabetes, Insulin Sensitivity/Resistance, Inflammatory Response, Fatty Acids, Omega-3
- Trial name
- NCT04496154
- Testing
- Omega-3 fatty acids (2.7 g/d, EPA:DHA, 2:1)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- May Faraj, PDt, PhD
Age-related Macular Degeneration, Cataract
Age-Related Eye Disease Study 2 (AREDS2)
Oral supplementation with the Age-Related Eye Disease Study (AREDS) formulation (antioxidant vitamins C and E, beta carotene, and zinc) has been shown to reduce the risk of progression to advanced age-related macular degeneration…
- Trial name
- AREDS2 (NCT00345176)
- Testing
- Lutein/zeaxanthin, DHA/EPA, Lutein/zeaxanthin and DHA/EPA
- Where
- 91 sites in United States
- Volunteers
- 4,203 people
- Sponsor
- National Eye Institute (NEI)
Metabolic Syndrome
Pivotal Assessment of the Effects of Bioactive on Health and Wellbeing. From Human Genome to Food Industry
This is a multi-centre, randomised, double-blind, placebo-controlled, parallel-arm dietary intervention study. In total, 800 men and women at risk for Metabolic Syndrome (MS) will be recruited.
- Trial name
- PATHWAY-27 (NCT02702713)
- Testing
- Dairy BEF, Egg BEF, Bakery BEF
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Preeclampsia
Docosahexaenoic Acid Serum Levels in Patients With Preeclampsia
By comparing the blood levels of docosahexaenoic acid (DHA) in preeclamptic patients with normal pregnant women, we aim to reveal the relationship between these markers, which are known to be effective on metabolic function, and…
- Trial name
- NCT05591638
- Volunteers
- 90 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Healthy Diet
Bioavailability and Pharmacodynamics of EPA and DHA From Fortified Soymilk and Capsules
This study will compare the algae oil fortified soymilk to a commercial algae oil capsule containing the same base oil with the goal of demonstrating equivalent or greater accumulation of EPA and DHA in blood lipid pools.
- Trial name
- NCT05802797
- Testing
- Algae Oil Fortified Soymilk, Algae Oil Capsule
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Bipolar Disorder
Omega-3 Fatty Acids in Bipolar Disorder
This is a 12 month study of omega-3 fatty acids in bipolar disorder. This study will be a 12-month, parallel group, double-blind comparison of the prophylactic efficacy of omega-3 fatty acids vs.
- Trial name
- NCT00010868
- Testing
- Omega-3 Fatty Acids
- Where
- 2 sites in United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Hypertension in Pregnancy
Docosahexaenoic Acid Supplementation of Women With Hypertension in Pregnancy to Improve Endothelial Health
The Investigator would like to see if taking a DHA supplement at a dose recommended for heart health will improve brachial artery dilation (relaxation) and help blood pressure.
- Trial name
- DHA-2 (NCT02137408)
- Testing
- Docosahexaenoic acid 200 mg, Docosahexaenoic acid 1000 mg
- Where
- United States
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Atherosclerosis, Low-density Lipoproteins Aggregation Susceptibility
The Effect of E-EPA on Circulating LDL and Plasma Lipid Metabolism
40-70 healthy volunteers of ages 18 to 65 participate in a E-EPA-diet where 3,9 grams of E-EPA is added to their normal diet and lifestyles for a month.
- Conditions
- Atherosclerosis, Low-density Lipoproteins Aggregation Susceptibility, Low-density Lipoprotein Lipid Composition, Cardiovascular Diseases
- Trial name
- EPA&LDL (NCT04152291)
- Testing
- Ethyl-Eicosapentaenoic Acid (E-EPA)
- Where
- Finland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wihuri Research Institute
Morbid Obesity
Intake of Omega 3 in Morbidly Obese Patients
Ingestion of capsules of omega 3 EPA and DHA, with 1.8 g of EPA and 1.2 g DHA for morbidly obese patients, will improve the inflammatory status? C-reactive protein? Weight?
- Trial name
- NCT02113696
- Testing
- Omega 3 intake, morbid obesity
- Volunteers
- 46 people
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Gastric Cancer, Colorectal Cancer
Effect of Enteral Nutrition Rich in Eicosapentaenoic Acid (EPA) on Patients Receiving Chemotherapy for GI Tumor
Malnutrition is frequently seen in patients on chemotherapy suffering from gastric/colorectal cancer and may worsen the outcome. EPA, a sort of ω-3 PUFA, can modulate immune system.
- Conditions
- Gastric Cancer, Colorectal Cancer, Chemotherapy
- Trial name
- NCT01048463
- Testing
- Nutriall, LDEPA, HDEPA
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Sun Yat-sen University