Clinical trials: Donor
Normal PBPC Donors
Open-Label Trial of Peripheral Blood Progenitor Cell (PBPC) Mobilization by Filgrastim in Normal Donors
The purpose of this study is to clinically evaluate the spleen during PBPC mobilization by filgrastim in normal donors.
- Trial name
- NCT00115128
- Testing
- filgrastim
- Volunteers
- 309 people
- Sponsor
- Amgen
Donors Safety
Causes of Disqualification of Egyptian Potential Living Liver Donors
Due to absence of Deceased-donors in Egypt, Living-donor liver transplantation (LDLT) has emerged as an option to the traditional deceased-donor transplantation procedure.
- Trial name
- NCT01809249
- Where
- Egypt
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Egg Donor Recipient Characteristics
Egg Donor Recipient Characteristics Preferences
To identify the characteristics in an egg donor that are important to a recipient and to see if those characteristics change over time.
- Trial name
- NCT01219491
- Where
- 3 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Anonymous Donors
Study of Ovum Donors After Donation
To explore the attitudes and reactions of ovum donors prospectively after ovum donation and to follow their medical histories.
- Trial name
- NCT01219374
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure
Long Term Minor Sibling Donor Well-Being
The goal of this research study is to understand what it is like for a young person to have a sick family member and what it is like to donate bone marrow or stem cells for a sick family member. Primary Aims: 1.
- Conditions
- Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure, Disturbance of Emotions Specific to Childhood and Adolescence, Transmission, Blood, Recipient/Donor
- Trial name
- NCT00667784
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Nephrectomy, Laparoscopic Donor Nephrectomy
Intravenous Ketorolac for Postoperative Pain in Laparoscopic Donor Nephrectomy
The purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having laparoscopic surgery to donate a kidney.
- Trial name
- NCT00765232
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Mayo Clinic
Split-thickness Skin Graft Donor Sites
Clinical Study on Veloderm for the Treatment of Split-thickness Skin Graft Donor Sites
This study is a multi-center, randomized, open and paralleled positive control study for evaluating the safety and efficacy of Veloderm in treatment of split-thickness skin graft donor sites.
- Trial name
- NCT01512017
- Testing
- Crystalline cellulose simple occlusive dressing, Vaseline
- Volunteers
- 96 people
- Sponsor
- Lee's Pharmaceutical Limited
Living Renal Donor
Living Renal Donor MRI Study
Accurate preoperative evaluation of a potential living renal donor's anatomy, vasculature and function is crucial to ensure optimal outcomes for both kidney donor and recipient in transplantation.
- Trial name
- NCT01280851
- Testing
- Magnetic Resonance Imaging
- Sponsor
- University Health Network, Toronto
Healthy Donors, HIV Positive
Evaluation of a Human Immunodeficiency Virus (HIV) Blood Screening Assay
To test blood samples from volunteer donors of whole blood and blood components using a new investigational test that detects human immunodeficiency virus (HIV) infection.
- Trial name
- NCT00686205
- Testing
- collection of follow-up sample based on PRISM HIV O Plus result
- Where
- 7 sites in United States
- Volunteers
- 24,111 people, healthy volunteers welcome
- Sponsor
- Abbott Diagnostics Division
Living Donor Liver Transplantation, Reperfusion Injury
Magnesium Administration in Liver Transplantation and Reperfusion Injury
The purpose of this study is to evaluate the effect of intravenous magnesium infusion before reperfusion with employing some clinical parameters including blood lactate levels, because the intraoperative changes in the blood…
- Trial name
- NCT00994981
- Testing
- magnesium, normal saline
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- The Catholic University of Korea
Living Donor Liver Transplantation
Population Pharmacokinetics of Fentanyl in Patients Undergoing Living Donor Liver Transplantation
The aim of this study was to characterize pharmacokinetics of fentanyl during and after Living Donor Liver Transplantation (LDLT), using population pharmacokinetic analysis with non linear mixed effects modeling.
- Trial name
- NCT01144312
- Testing
- Fentanyl
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Renal Failure, Renal Transplantation
A Reduced 11-b-HSD Activity, a Novel Mechanism of Salt Sensitivity and Hypertension After Renal Allograft Donation?
Consecutive living-kidney donor candidates (n=100) will be recruited after being accepted for donation according to official guidelines.
- Conditions
- Renal Failure, Renal Transplantation, Living Donors
- Trial name
- NCT01009229
- Testing
- Low and high salt diets
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Transplantation, Living Donors
Randomized Trial of Cyclosporine and Tacrolimus Therapy With Steroid Withdrawal in Living-Donor Renal Transplantation
The use of steroids after kidney transplantation has been challenged because of variable adverse effects which may increase the patient morbidity and mortality.
- Trial name
- NCT00777933
- Testing
- tacrolimus, cyclosporine
- Where
- South Korea
- Volunteers
- 131 people
- Sponsor
- Samsung Medical Center
Acute Myeloid Leukemias, Advanced Hematological Malignancies
Haploidentical Transplantation With Early Adoptive Transfer of CD56+CD3- NK Cells
Experimental and clinical data suggest that alloreactive NK cells can reduce the risk of graft-rejection, GvHD and leukemic relapse after HLA-mismatched transplantation.
- Conditions
- Acute Myeloid Leukemias, Advanced Hematological Malignancies, Indication for Allogeneic Stem Cell Transplantation, no HLA-identical Donor Available
- Trial name
- NCT01220544
- Testing
- Haploidentical transplantation with donor NK cells
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Charite University, Berlin, Germany
Patients Receiving a Kidney From a Non-Heart-Beating Donor
PROTECT: Prospective Trial on Erythropoietin in Clinical Transplantation
Randomized, double blind, placebo controlled, prospective trial investigating the effect of erythropoietin in renal transplantation. The investigators postulate that erythropoietin reduces the risk of delayed graft function.
- Trial name
- NCT00157300
- Testing
- Epoetin beta
- Where
- 2 sites in Netherlands
- Volunteers
- 92 people
- Sponsor
- Leiden University Medical Center
End Stage Liver Disease, Living Donor
Effect of Intermittent Hepatic Inflow Occlusion During Donor Hepatectomy In Living Donor Liver Transplantation
Intermittent hepatic inflow occlusion (IHIO), also called Pringle maneuver, is a safe and effective procedure for major hepatectomy in patients with liver disease.
- Trial name
- NCT01171742
- Testing
- Intermittent hepatic inflow occlusion (IHIO)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Treatment of Donor Site Burns
Multi-Center, Prospective, Randomized, Comparison of AWBAT™-D vs. Xeroform™ or Glucan II™ for Treatment of Donor Sites in Burn Surgery
The purpose of this study is to compare the rate of healing and the non-adherence of three types of dressings. The study will also compare rate of infection, scarring and perception of pain associated with treatment.
- Trial name
- AWBAT-D (NCT00964470)
- Testing
- AWBAT™-D and XEROFORM™ OR GLUCAN II™ dressings
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aubrey Inc.
Organ Donor
Healthcare Access and Utilization Among Living Kidney Donors
This is a mailed survey to persons who served as living kidney donors at Saint Barnabas Medical Center. The experimental component of this study (the clinical trial) is a randomized trial of two monetary incentives for the living…
- Trial name
- NCT01009125
- Testing
- $2 cash, $5 cash
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- St. Barnabas Medical Center
Partial-thickness Skin Donor Sites
Altrazeal™ Versus Aquacel® Ag for Partial Thickness Skin Donor Sites
The primary objective of the study is to evaluate the time to wound healing in skin graft donor sites with a new treatment (Altrazeal dressing) compared to standard of care treatment (Aquacel Ag- Carboxymethylcellulose dressing)…
- Trial name
- NCT01062204
- Testing
- Altrazeal, Aquacel Ag
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- ULURU Inc.
Reepithelialization of Skin Graft Donor Sites
Clinical Comparative Trial of a Modified Polyurethane Dressing and Aquacel
The almost single disadvantage of conventional polyurethane film dressings, an uncontrolled leakage, is probably as often described as its numerous advantages for split-thickness skin graft (STSG) donor sites.
- Trial name
- NCT01055925
- Testing
- modified polyurethane film dressing (OpSite, Smith&Nephew, London, UK), Aquacel® (ConvaTec, Skillman, NJ, USA), sodium carboxy-methylcellulose hydrocolloid polymer dressing
- Where
- Germany
- Sponsor
- Klinik Bogenhausen