Clinical trials: Dorsal Root Ganglion
Herpes Zoster
Esketamine Combined With PRF of DRG for Acute/Subacute Zoster-associated Pain
To assess the 1-month effects and safety of esketamine - PRF -standardized drug treatment against PRF -standardized drug treatment acute/subacute zoster-associated pain (ZAP) patients.
- Trial name
- NCT06914206
- Testing
- esketamine group, PRF group
- Where
- China
- Volunteers
- 184 people
- Sponsor
- Beijing Tiantan Hospital
Failed Back Surgery Syndrome, Complex Regional Pain Syndrome (CRPS)
A Study to Confirm the Safety of High Frequency DRG Stimulator in Patients With Chronic Lower Limb Pain
This study is a prospective, single-arm, open label, single center pilot study to confirm the safety of a ultrahigh frequency DRG stimulator in patients with chronic lower limb pain. The actual trial length is 5 days.
- Trial name
- NCT03285113
- Testing
- GiMer Medical MN 1000 External Stimulator
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- GiMer Medical
Chronic Pain
Study to Evaluate the Effectiveness of DRG Stimulation for Discogenic Low Back Pain
The purpose of this prospective post market observational pilot study is to evaluate the effect of DRG stimulation in the management of chronic discogenic pain in subjects who are refractory to other available treatments.
- Trial name
- NCT02587637
- Testing
- Dorsal root ganglion (DRG) stimulation
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Abbott Medical Devices
CRPS (Complex Regional Pain Syndrome) Type I
Physiological Parameters in CRPS Patients Treated With Dorsal Root Ganglion Stimulation
1. Objective and Rationale: The study seeks to evaluate how Dorsal Root Ganglion Stimulation (DRGS) influences autonomic functions in patients suffering from Complex Regional Pain Syndrome type I (CRPS I), offering new metrics…
- Trial name
- EPIC-DRG (NCT07147140)
- Testing
- dorsal root ganglion stimulation cessation
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- AZ Delta
Chronic Post Surgical Pain
A Post Market Study to Assess the Spinal Modulation Dorsal Root Ganglion Stimulator System in Chronic Post Surgical Pain
20-SMI-2013 is a post market, observational, questionnaire based study to assess the effectiveness of the commercially available Axium neurostimulator in the management of chronic post surgical pain
- Trial name
- NCT02335229
- Testing
- Axium DRG Neurostimulator
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Abbott Medical Devices
Neuropathic Pain
Measuring Evoked Potentials From the Spinal Cord and Dorsal Root Ganglion
The purpose of this study is to determine the feasibility of recording evoked compound action potentials (ECAPs) and somatosensory evoked potentials (SSEPs) from the spinal cord (SC) and Dorsal root ganglions (DRG), and their…
- Trial name
- ECAPS SCS (NCT03976219)
- Testing
- ECAPS Closed Loop SCS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Myofascial Trigger Points, Cervicogenic Headache
Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Chronic Cervicogenic Headache
Chronic cervicogenic headache is a common disease in China, with a high incidence among the elderly, and has a significant impact on patients' quality of life.
- Conditions
- Myofascial Trigger Points, Cervicogenic Headache, Dorsal Root Ganglion
- Trial name
- NCT07347730
- Testing
- MTrPs injection, C2 dorsal root ganglion blocks
- Where
- China
- Volunteers
- 1,036 people
- Sponsor
- Beijing Tiantan Hospital
Spinal Cord Injuries, Lower Motor Neuron Disease
Dorsal Root Ganglion Stimulation After Lower Motor Neuron Damage
The purpose of this study is to study sensorimotor circuit activity generated in response to temporarily implanted dorsal root ganglion stimulation by recording from muscles of the lower extremities as well as functional outcomes…
- Trial name
- NCT07619300
- Testing
- Abbot Dorsal Root Ganglion Neurostimulator
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Peter J. Grahn, Ph.D.
Pain, Intractable, Pain, Chronic
Intermittent vs. Continuous Dorsal Root Ganglion Stimulation
The purpose of this study is to evaluate and compare the therapeutic efficacy of intermittent Dorsal Root Ganglion Stimulation (DRG-S) to standard continuous stimulation in patients with chronic intractable pain
- Trial name
- NCT04727216
- Testing
- Dorsal Root Ganglion Stimulation (DRG-S)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Spine and Pain Institute of New York
Phantom Limb Pain
Study of Phantom Limb Pain Suppression Using Neuromodulation Methods
This study assesses the effectiveness of neuromodulation in alleviating pain through the stimulation of peripheral nerves. The research involves implanting electrodes for test stimulation of peripheral nerves (PNS - Peripheral…
- Trial name
- NCT06644807
- Testing
- Motor Cortex Stimulation, Spinal cord stimulation, Peripheral Nerve Stimulation
- Where
- 2 sites in Russia
- Volunteers
- 50 people
- Sponsor
- Skolkovo Institute of Science and Technology
Deep Learning
Automated Detection and Diagnosis of Pathological DRGs in PHN Patients Using Deep Learning and Magnetic Resonance
Here, this study aimed to develop an automated system for detecting and diagnosing lesion DRGs in PHN patients based on deep learning.
- Trial name
- NCT06274502
- Testing
- YOLOv8
- Where
- 2 sites in China
- Volunteers
- 41 people
- Sponsor
- Huazhong University of Science and Technology
Post Surgical Groin Pain
a BavaRiAn eValuatiOn of Dorsal Root Ganglion (DRG) Stimulation for the Treatment for Chronic Post Surgical Pain of the Groin
15-SMI-2013 is a post market, observational, questionnaire based study to assess the effectiveness of the commercially available Axium neurostimulator in the management of chronic post surgical groin pain
- Trial name
- BRAVO (NCT02346656)
- Testing
- Implantation with the commercially available Axium neurostimulator
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Abbott Medical Devices
Cancer-related Problem/Condition
Combined Fluoroscopy and CT Guided Radiofrequency Ablation of Thoracic Dorsal Root Ganglia in Severe Thoracic Pain
In the current study, extra-guidance other than conventional fluoroscopy - will be integrated to improve the success of the transforaminal approach to the thoracic dorsal root ganglia (DRG).
- Trial name
- NCT03533413
- Testing
- combined CT-fluroscopy, standard fluroscopy
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- National Cancer Institute, Egypt
Postherpetic Neuralgia
Dorsal Root Ganglion Stimulation in Postherpetic Neuropathy
This is a prospective, multicenter observational study evaluating the efficacy of ganglion stimulation (medical device) in cases of post-herpetic neuropathy.
- Trial name
- DRGs (NCT06225960)
- Where
- Italy
- Volunteers
- 77 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
RADICULAR PAIN
Efficacy of Pulse Radiofrequency Durations in Lumbosacral Pain
Brief Summary: This study aims to compare the efficacy of short-duration (240 sec) and long-duration (480 sec) pulsed radiofrequency (PRF) applications on pain, functionality, patient satisfaction, and side effect profiles in…
- Trial name
- NCT06748469
- Testing
- The duration of the intervention will be 240 seconds, Dorsal Root Ganglion pulsed radiofrequency 480sec
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Complex Regional Pain Syndrome (CRPS)
TARGET Post-Approval Study
The purpose of this prospective, multicenter, single arm post-approval study is to demonstrate continued safety of the Axium and Proclaim Neurostimulator System for dorsal root ganglion (DRG) stimulation.
- Trial name
- TARGET PAS (NCT02800863)
- Testing
- Dorsal Root Ganglion (DRG) Stimulation (Axium™ Neurostimulator System), Dorsal Root Ganglion (DRG) Stimulation (Proclaim™ Neurostimulator System)
- Where
- 44 sites in United States
- Volunteers
- 426 people
- Sponsor
- Abbott Medical Devices
Neuropathic Pain, Pain, Chronic
TransGrade Multimodal Neuromodulation of the Dorsal Root Ganglion Ensemble for Refractory Neuropathic Pain
This a single center study comparing two forms of electrical stimulation: sub-sensory burst stimulation (DRG-Burst3D) and standard low frequency stimulation (DRG-LF) in the dorsal root ganglion of subjects diagnosed with…
- Trial name
- NCT03318250
- Testing
- Dorsal Root Ganglion Stimulation
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Dorsal Root Ganglion, Pulsed Radiofrequency
The Effect of Sensory Stimulation Threshold on the Efficacy of Pulsed Radiofrequency Applied to the Dorsal Root Ganglion in Patients with Chronic Lumbar Radicular Pain
Lomber dorsal root ganglion pRF is an interventional treatment options in the treatment of lumbar radicular pain. The goal of this study is to investigate the effect of sensory threshold outcomes on pain severity during dorsal…
- Conditions
- Dorsal Root Ganglion, Pulsed Radiofrequency, Chronic Pain, Lumbar Radiculopathy
- Trial name
- NCT06756893
- Testing
- Dorsal Root Ganglion Pulsed Radiofrequency
- Volunteers
- 150 people
- Sponsor
- Ankara University
Pulsed Radiofrequency, Lumbar Radiculopathy
High-Voltage Pulsed Radiofrequency of the Lumbar Dorsal Root Ganglion for the Treatment of Chronic Lumbar Radicular and Neuropathic Pain; A Prospective, Doble-blinded and Randomized Controlled Trial
The management of chronic lumbar radicular and neuropathic pain is complex and the treatment success rates are low. Pulsed radiofrequency (PRF) has been described in these cases.
- Trial name
- Radiofrequency (NCT06264297)
- Testing
- Radiofrequency
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Consorci Sanitari de Terrassa
Pain, Neuropathy;Peripheral
Morphological and Metabolic Changes of Dorsal Root Ganglion and Sympathetic Ganglion in Patients With Postherpetic Neuralgia on MRI
Object: Postherpetic neuralgia (PHN) is pain that persists for 1-3 months after herpes zoster onset. It is the most common complication of herpes zoster and occurs in 15-40% of patients with herpes zoster.
- Trial name
- NCT04880408
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huazhong University of Science and Technology