Clinical trials: Dosimetry
Healthy
A Phase I Study in Healthy Volunteers to Assess Safety of BMS747158
The purpose of this clinical research study is to learn the safety and biodistribution of BMS747158 in normal, healthy volunteers.
- Trial name
- NCT00707499
- Testing
- BMS747158
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Lantheus Medical Imaging
Carcinoma, Castration Resistant Prostatic Neoplasms
Impact of Body Composition on Dosimetry of 177Lu-PSMA Radioligand Therapy
COCORIVO is an interventional study evaluating the impact of body composition on dosimetry of 177Lu-PSMA radioligand therapy in patients with metastatic castration-resistant prostate cancer (mCRPC).
- Trial name
- COCORIVO (NCT07587814)
- Testing
- 177Lu-PSMA-617 + SPECT/CT dosimetry
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Henri Becquerel
Healthy Volunteers, Cancer Patients
Clinical Study of 68Ga-LNC1007 Injection PET/CT
This study is a single-arm, single-center trial aimed at evaluating the safety, pharmacokinetics, biodistribution and dosimetry of 68Ga-LNC1007 Injection in adult healthy volunteers and solid tumor patients.
- Trial name
- NCT06463782
- Testing
- 68Ga-LNC1007 Injection
- Where
- Singapore
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Yantai LNC Biotechnology Singapore PTE. LTD.
Advanced/Metastatic HER2-positive Breast, Gastric, Gastroesophageal Junction Cancer With Disease Progression Following Anti-HER2 Standard of Care Treatment
A Study to Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer
This is a Phase 1/2 multi-center, open label, dose escalation and dose expansion study to evaluate safety, tolerability, dosimetry, pharmacodynamics (PD), and efficacy of the targeted radionuclide therapeutic CAM-H2 in patients…
- Trial name
- NCT04467515
- Testing
- CAM-H2
- Where
- 12 sites in United States, Canada
- Volunteers
- 13 people
- Sponsor
- Precirix
Graves' Disease
Radioactive Iodide Therapy for Pediatric Graves' Disease
The investigators hypothesize that 131I is an effective therapy for children with Graves' Disease (GD) and will not be associated with long-term cancer risks when used in older children, but may be associated with excessive…
- Trial name
- NCT01269749
- Testing
- RAI treatment, ATD Group
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Florida
Primary Malignant Liver Neoplasm
Yttrium-90 (Y90) Glass Microspheres PET/CT in Imaging Patients With Liver Tumors
This clinical trial studies how well yttrium-90 (Y90) glass microspheres positron emission tomography (PET)/computed tomography (CT) works in imaging patients with liver tumors .
- Trial name
- NCT03109262
- Testing
- Computed Tomography (CT), Positron Emission Tomography (PET), 90-Yttrium (Y-90) Glass Microspheres
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Stanford University
Recurrent Glioblastoma (WHO-Grade IV Glioma), Recurrent Glioblastoma
Dosimetry, Safety, and Efficacy Study of [177Lu]Lu-XT771 in Patients With Recurrent Glioblastoma
The primary objective of this study is to evaluate the dosimetry, safety, and tolerability of the investigational radiopharmaceutical [177Lu]Lu-XT771 in patients with recurrent glioblastoma, an aggressive form of brain cancer.
- Conditions
- Recurrent Glioblastoma (WHO-Grade IV Glioma), Recurrent Glioblastoma, Glioblastoma (GBM), Recurrent Glioblastoma IDH Wildtype
- Trial name
- NCT07648823
- Testing
- [177Lu]Lu-XT771
- Where
- 2 sites in China
- Volunteers
- 5 people
- Sponsor
- Beijing Tiantan Hospital
Prostate Cancer
A Phase I Study to Evaluate the Safety and Dosimetry of Imaging With 68Ga-OncoACP3 in Prostate Cancer
The aim of this study is to assess the safety and dosimetry of imaging with [68Ga]Ga-OncoACP3 in patients with prostate cancer.
- Trial name
- SWAP (NCT07600554)
- Testing
- [68Ga]Ga-OncoACP3
- Where
- 2 sites in Italy
- Volunteers
- 20 people
- Sponsor
- Philogen S.p.A.
Pain, Face
First-in-man Imaging of a New PET Radiotracer for Oxytocin Receptors
The investigators will test a new positron-emitting radiotracer to determine whether it is suitable for studying the oxytocin receptor by positron emission tomography (PET) in humans.
- Trial name
- NCT06955650
- Testing
- Imaging procedure to measure the distribution of a newly developed radiolabeled ligand for the oxytocin receptor
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Cancer of the Thyroid, Cancer of Thyroid
Evaluation of Lancet Blood Sampling for Radioiodine Dosimetry in Thyroid Cancer
Recently published European guidance recommends the evaluation of the radiation dose to the bone marrow in patients undergoing radioiodine therapy for thyroid cancer.
- Conditions
- Cancer of the Thyroid, Cancer of Thyroid, Thyroid Cancer, Thyroid Carcinoma
- Trial name
- NCT02658513
- Testing
- Lancet blood sampling, Standard intravenous blood sampling
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust