Clinical trials: Double Incontinence
Overactive Bladder
MILADY: A Randomized, Placebo-controlled Safety and Efficacy Trial of SSR240600C in Treatment of Overactive Bladder or Urge Urinary Incontinence.
To evaluate the safety and efficacy of SSR240600C versus placebo on clinical and cystometric parameters in patients with OAB and UUI.
- Trial name
- NCT00174798
- Testing
- SSR240600C, Tolterodine
- Where
- 22 sites in United States
- Volunteers
- 118 people
- Sponsor
- Sanofi
Localized Prostate Cancer, Postoperative Urinary Incontinence
Oxybutynin ER to Promote Early Continence Recovery After Robotic Prostatectomy: A Randomized Controlled Trial
The goal of this double-blind, randomized, placebo-controlled study is to evaluate whether oxybutynin chloride extended-release tablets can improve early continence recovery after robot-assisted radical prostatectomy (RARP) in…
- Trial name
- NCT06966778
- Testing
- Oxybutynin chloride extended-release tablets 5mg/tab, 2 tab, PO, qd.
- Where
- Taiwan
- Volunteers
- 135 people
- Sponsor
- National Taiwan University Hospital
Overactive Bladder
Clinical Study to Evaluate the Treatment Effect and Safety of BAY1817080 in Patients With Overactive Bladder (OAB)
The aim of the study is to determine how well the drug BAY1817080 works in OAB patients with urgency urinary incontinence (UUI), defined as involuntary leakage of urine, accompanied or immediately preceded by a sudden compelling…
- Trial name
- OVADER (NCT04545580)
- Testing
- BAY1817080
- Where
- 28 sites in Australia, Austria and 7 more
- Volunteers
- 99 people
- Sponsor
- Bayer
Overactive Bladder
A Confirmatory Study of KUC-7483 in Patients With Overactive Bladder
To evaluate the efficacy and the safety of KUC-7483 in overactive bladder patients.
- Trial name
- NCT01004315
- Testing
- KUC-7483, Tolterodine
- Where
- Japan
- Volunteers
- 750 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Stress Urinary Incontinence
Autologous Muscle Derived Cells for Female Urinary Sphincter Repair
This randomized, double-blind, placebo-controlled, multicenter, confirmatory study will evaluate the efficacy and safety of Cook MyoSite Incorporated Autologous Muscle-Derived Cells (generic name Iltamiocel) compared to a placebo…
- Trial name
- NCT01893138
- Testing
- Iltamiocel
- Where
- 29 sites in United States, Belgium and 1 more
- Volunteers
- 311 people
- Sponsor
- Cook MyoSite
Overactive Bladder
Evaluation of the Efficacy and Safety of Solabegron Tablets for Treatment of Overactive Bladder in Adult Women
This is a Phase 2b, multicenter, randomized, double-blind, placebo-controlled, parallel-group study designed to evaluate the efficacy, safety, and tolerability of solabegron immediate release low dose or high dose tablets…
- Trial name
- NCT03475706
- Testing
- Solabegron immediate release tablets, low dose, Solabegron immediate release tablets, high dose
- Where
- 86 sites in United States
- Volunteers
- 438 people
- Sponsor
- Velicept Therapeutics, Inc.
Urinary Incontinence
The Efficacy of Graminex® Flower Pollen Extracts in Healthy Women With Urinary Incontinence
The primary objective of this study is to investigate the effect of Graminex® Flower Pollen Extracts in healthy women with urinary incontinence.
- Trial name
- NCT05510999
- Testing
- Water soluble pollen extract fraction, Lipid soluble pollen extract fraction + water soluble pollen extract fraction, Lipid soluble pollen extract fraction
- Where
- Canada
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Graminex LLC
Stress Urinary Incontinence
Evaluation Of The Ability Of Fesoterodine To Increase Urethral Pressure In Stress Urinary Incontinence Patients
The hypothesis under evaluation is that fesotorodine may provide clinical benefit in the treatment of the condition of stress urinary incontinence
- Trial name
- NCT01042236
- Testing
- Fesoterodine
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Pfizer
Overactive Bladder, Urge Urinary Incontinence
Bryophyllum Pinnatum Versus Solifenacin Versus Placebo for Overactive Bladder
Overactive bladder (OAB) is an enigmatic condition that is treated symptomatically with anticholinergic drugs (gold standard 2013).
- Trial name
- BryoSoliP (NCT02129816)
- Testing
- Bryophyllum
- Where
- 2 sites in Switzerland
- Volunteers
- 9 people
- Sponsor
- University of Zurich
Stress Urinary Incontinence, Urge Incontinence
Urinary Stress Incontinence and Urgency in Women With EMSELLA
The purpose of this prospective study is to examine the safety and efficacy of high intensity focused electromagnetic (HIFEM) technology for the treatment of women with stress urinary incontinence (SUI), urge incontinence (UI)…
- Trial name
- NCT03877640
- Testing
- BTL EMSELLA
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- San Diego Sexual Medicine
Dual Incontinence, Fecal Incontinence
Sacral Neuromodulation in Dual Incontinence: Ultrasound and Afferent Nerve Sensation Assessment
Women with Dual Incontinence (DI) (both Urinary Incontinence (UI) and Fecal Incontinence (FI)) often have more bothersome symptoms, quality of life impact, and sexual dysfunction than those with just UI or FI.
- Conditions
- Dual Incontinence, Fecal Incontinence, Urinary Incontinence, Sacral Neuromodulation
- Trial name
- SaNDI (NCT02357784)
- Testing
- Neurometer
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Northwestern University
Urinary Incontinence
Study to Evaluate the Safety and Efficacy of DR-3001 Versus Placebo in Women With Overactive Bladder
This is a placebo-controlled, double-blind study to evaluate the safety and efficacy of two doses of DR-3001 in women with overactive bladder who have symptoms of predominant or pure urge incontinence, urinary urgency and…
- Trial name
- NCT00196404
- Testing
- DR-3001a, DR-3001b
- Where
- 48 sites in United States, Canada
- Volunteers
- 800 people
- Sponsor
- Duramed Research
Overactive Bladder, Urinary Urge Incontinence
Reduction of Bladder Injection Pain With Belladonna Opiate Suppository
The purpose of this study is to test whether using belladonna \& opiate suppositories (B\&Os) can improve patient discomfort during Onabotulinumtoxin A (BoNT) injection into the bladder for treatment of overactive bladder…
- Conditions
- Overactive Bladder, Urinary Urge Incontinence, Urinary Bladder, Neurogenic, Painful Bladder Syndrome
- Trial name
- ROBIN (NCT02600715)
- Testing
- Onabotulinumtoxin A (BoNT), belladonna, Morphine
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Edgar LeClaire, MD
Urologic Diseases, Urinary Bladder Diseases
A Study to Evaluate the Efficacy, Safety and Tolerability of Mirabegron and Solifenacin Succinate Alone and in Combination for the Treatment of Overactive Bladder
The purpose of this study is to examine how well two medicines in combination (solifenacin succinate and mirabegron) work in the treatment of bladder problems over a 12-week period.
- Conditions
- Urologic Diseases, Urinary Bladder Diseases, Urological Manifestations, Signs and Symptoms
- Trial name
- Symphony (NCT01340027)
- Testing
- Mirabegron, Solifenacin succinate
- Where
- 133 sites in Belarus, Belgium and 18 more
- Volunteers
- 1,307 people
- Sponsor
- Astellas Pharma Europe B.V.
Urinary Incontinence
DBPC Trial to Evaluate the Safety, Tolerability and Efficacy of Oral Litoxetine in Subjects With Urinary Incontinence
This study will explore the safety, tolerability and efficacy of litoxetine in men and women who suffer from urinary incontinence
- Trial name
- NCT03397771
- Testing
- Litoxetine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Ixaltis SA
Incontinence-associated Dermatitis
COPPER: A Trial Evaluating Copper-based Products for Incontinence-associated Dermatitis
As there are currently no evidence on the benefit of absorbing incontinence products with copper to stabilize IAD in the elderly, thus, this study will assess the capacity and safety of an absorbing incontinence products with a…
- Trial name
- NCT06726707
- Testing
- Diaper with a copper-based product + usual care, Barrier product with common diaper
- Sponsor
- Hospital Israelita Albert Einstein
Urinary Urge, Urge Incontinence
Solifenacin Succinate Versus Placebo in Inner City Women Ages 20-45 With Overactive Bladder
In this study we hope to establish the prevalence of urinary urge symptoms (with or without incontinence) in a multicultural, underserved, hospital clinic population in women between the ages of 20 and 45.
- Conditions
- Urinary Urge, Urge Incontinence, Overactive Bladder
- Trial name
- NCT00773552
- Testing
- solifenacin succinate
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stamford Hospital
Urinary Incontinence
Study to Determine The Effectiveness Of Detrusitol In Patients Diagnosed With OAB
The purpose of this study is to evaluate the effectiveness of Detrusitol (tolterodine tartrate) SR, 4 mg once daily, on patient's perception of the symptoms of overactive bladder and which of these bothersome symptoms are…
- Trial name
- NCT00143377
- Testing
- tolterodine SR, overactive bladder
- Volunteers
- 600 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Urinary Bladder, Overactive
Study to Test the Long Term Safety and Efficacy of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder
The study is intended to test the safety, tolerability, efficacy of two doses of long term once daily (qd) treatment of Mirabegron in patients with symptoms of overactive bladder and secondly to compare these with active…
- Trial name
- TAURUS (NCT00688688)
- Testing
- Mirabegron, Tolterodine
- Where
- 308 sites in United States, Australia and 28 more
- Volunteers
- 2,792 people
- Sponsor
- Astellas Pharma Inc