Clinical trials: Drinking, Alcohol
Depressive Disorders, Alcohol Use Disorders
Implementing a Blended Care Model That Integrates Mental Healthcare and Primary Care Using Telemedicine and Care Management for Patients With Depression or Alcohol Use Disorder in Small Primary Care Clinics
Integrating mental health treatments into the primary care delivered at Community Based Outpatient Clinics(CBOCs) that are geographically accessible to rural Veterans is a major priority for the Department of Veterans Affairs.
- Conditions
- Depressive Disorders, Alcohol Use Disorders, Post-traumatic Stress Disorder (PTSD)
- Trial name
- Tele-PCMHI (NCT02713217)
- Testing
- Usual Care, Blended Telemedicine-Based Integrated Care
- Where
- United States
- Volunteers
- 318 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury (TBI), Hazardous and Harmful Alcohol Use
Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI
The goal of the proposed project is to improve the treatment of veterans with co-occurring traumatic brain injury (TBI) and hazardous or harmful alcohol use.
- Trial name
- VAT (NCT01750268)
- Testing
- Medical Management Counseling, Topiramate
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Alcoholism
Levetiracetam XR in Very Heavy Drinkers
The primary objectives of this study are to assess the efficacy of levetiracetam XR in increasing the percentage of subjects with no heavy drinking days and in reducing the weekly percentage of heavy drinking days in subjects…
- Trial name
- NCIG 002 (NCT00970814)
- Testing
- BBCET, Levetiracetam XR, Sugar Pill
- Where
- 5 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder
Medication Development in Alcoholism: Apremilast Versus Placebo
The primary hypotheses under test are that alcohol dependent subjects treated with apremilast will report decreased craving for alcohol following alcohol exposure in the laboratory and report significantly less drinking under…
- Trial name
- NCT03175549
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- The Scripps Research Institute
Alcohol Drinking
Investigating the Interactions of AZD0530 With Alcohol in Social Drinkers
The purpose of this alcohol-interaction pilot study is to provide information on the effect of AZD0530 (Saracatinib) on the pharmacokinetics of alcohol and on alcohol responses, including stimulation, sedation, intoxication, body…
- Trial name
- NCT02732587
- Testing
- Saracatinib
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Bipolar Disorder, Alcohol Drinking
Acute Alcohol Response In Bipolar Disorder: a fMRI Study
Alcohol use disorders (AUDs) affect up to 60% of individuals with bipolar disorder during their lifetime-a rate 3 to 5 times higher than what occurs in the general population.
- Conditions
- Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
- Trial name
- BACS (NCT04063384)
- Testing
- alcohol beverage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Alcohol Drinking, Anxiety Disorders
Retraining Attention to Treat Alcohol Dependence and Social Anxiety
The purpose of this research is to test a computerized intervention for people with co-occurring social anxiety and alcohol dependence.
- Trial name
- AMP (NCT01886716)
- Testing
- Anxiety Attention Training, Alcohol Attention Training, Control Training
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Cincinnati
Alcohol Abuse, Alcohol Use Disorder
Examining Alcohol Consumption, Perceptions, and User Experience of Alcohol Moderation Strategies
The primary aims of the study are to assess the user experience and initial efficacy of a mobile application designed to reduce problematic alcohol use.
- Conditions
- Alcohol Abuse, Alcohol Use Disorder, Alcohol Abuse, Episodic
- Trial name
- ALCMOD (NCT04286867)
- Testing
- Alcohol Moderation Mobile Application, Alcohol Moderation Drink Tracker
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kent State University
Alcohol Use Disorder, Eligible to go Into the MRI Scanner
Clinical Intervention in Alcohol Use Disorder
Long-term abstinence from alcohol is supported by a compensatory mechanism in functional brain connectivity, a potential brain biomarker that could be an intervention target.
- Conditions
- Alcohol Use Disorder, Eligible to go Into the MRI Scanner, Short-term Abstinence From Alcohol Use (2 Week Abstinent)
- Trial name
- NCT02168400
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Minnesota
Underage Drinking
Parental Research on Interventions for Social Media
The prevalence of underage alcohol use continues to be a public health concern. Numerous studies have reported associations between teen drinking tendencies and parental attitudes and beliefs, parental awareness of teen drinking…
- Trial name
- PRISM (NCT04333966)
- Testing
- Interactive Social Networking Site Parent Based Intervention, Active Control
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Alcohol Use Disorder, Alcohol Abuse
Talk Therapy by Phone to Promote Treatment for Alcohol Problems
A small percentage of individuals with alcohol use disorder (AUD) obtain alcohol-related care despite research showing that treatment is effective.
- Trial name
- NCT03758274
- Testing
- CBT by Phone to Promote Treatment, Reading the Subject a Pamphlet on Obtaining Alcohol Use Disorder Treatment
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Rochester
Alcohol Abuse
Study of Mobile Phone Delivered Intervention to Reduce Alcohol Consumption
In this study, the investigators will be developing and testing a mobile phone text message intervention to reduce alcohol use for people at risk of alcohol dependence.
- Trial name
- mROAD (NCT02158949)
- Testing
- mROAD
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Southern California
Major Depressive Disorder, Alcohol Use Disorder
Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial
Recent reports have shown that alcohol misuse is a particularly serious problem among the 18 to 25 year old age group. Previous medication trials with SSRI antidepressants among young adults with co-occurring depressive…
- Trial name
- YAAD-P (NCT02646449)
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alcohol Use Disorder
Alcohol, Inflammation, and Mindfulness Study (AIM)
The goal of the AIM Study is to examine the effectiveness of Mindfulness Based Relapse Prevention (MBRP) versus Relapse Prevention (RP) for the treatment of Alcohol Use Disorders (AUD) by implementing an 8-week long intervention…
- Trial name
- NCT02994043
- Testing
- Mindfulness-Based Relapse Prevention Therapy, Relapse Prevention Therapy
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of Colorado, Denver
Opioid Use Disorder, Alcohol Use Disorder
Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study
The purpose of this study is to learn how best to treat substance use disorders in an HIV clinic setting. Specifically, the purpose of this pilot study is to learn if extended-release naltrexone (XR-NTX) would be a feasible and…
- Trial name
- CHOICES (NCT01908062)
- Testing
- Extended Release Naltrexone, Treatment As usual
- Where
- 2 sites in United States, Canada
- Volunteers
- 51 people
- Sponsor
- Oregon Health and Science University
Alcohol Use Disorder
Brief Family-involved Treatment for Alcohol Use Disorder
Family-involved treatments for alcohol use disorders (AUDs) hold considerable promise to improve engagement and compliance with treatment and improve treatment outcomes.
- Trial name
- B-FIT (NCT05545644)
- Testing
- Brief Family-Involved Treatment for Alcohol Use Disorder
- Volunteers
- 35 people
- Sponsor
- University of New Mexico
Type 2 Diabetes
Moderate Alcohol Intake Among Patients With Type 2 Diabetes
Our specific aim is to explore the effect of moderate alcohol intake on parameters of glycemic index and lipid profile among patients with type 2 diabetes.
- Trial name
- NCT00295334
- Testing
- alcohol
- Volunteers
- 109 people
- Sponsor
- Iris Shai
Alcohol Use Disorder
Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders
Evaluate the efficacy of CBT4CBT and clinician-delivered CBT relative to standard treatment for reducing alcohol use
- Trial name
- NCT02742246
- Testing
- Individual clinician-provided CBT, CBT4CBT
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Yale University
Alcohol Use Disorder
Alcohol Use and Mental Health - Pilot Test of Video-assisted Drinking Topography
The overall goal is to pilot test and establish a procedure for video-assisted alcohol topography and explore its utility as an indicator of alcohol use disorder.
- Trial name
- NCT03314454
- Testing
- Beer, Videotaped drinking session
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Use Disorder, Couples
Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT)
Alcohol Behavioral Couples Therapy (ABCT) is a manualized 12-session, weekly psychosocial intervention that simultaneously reduces alcohol use disorder (AUD) severity and improves relationship functioning.
- Trial name
- NCT03846505
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Medical University of South Carolina