Clinical trials: Drinking, Alcohol
Sexual Behavior, Alcohol Drinking
Men's Sexual Risk Behaviors: Alcohol, Sexual Aggression, and Emotional Factors
Although correct, consistent condom use can greatly reduce sexually transmitted infections and unplanned pregnancies, resistance of condom use is common among young adults.
- Conditions
- Sexual Behavior, Alcohol Drinking, Sexual Aggression, Emotions
- Trial name
- NCT03900650
- Testing
- High provocation manipulation, Low provocation manipulation, Alcoholic beverage
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Arizona State University
Alcohol Use Disorder
Oxytocin and Stress Response in Alcohol Use Disorder
Individuals with alcohol use disorder (AUD) will complete one functional Magnetic Resonance Imaging (fMRI) scanning visit. Prior to the scan, individuals will receive a nasal spray of either 24 international units (IU) of…
- Trial name
- NCT03610633
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Medical University of South Carolina
Alcohol Drinking, Adolescent, Drinking Behavior
Brief Intervention to Prevent Alcohol Socialization (BIPAS Alcohol)
Early alcohol socialization occurs within the family. This multi-level, high-reach, low-intensity intervention to prevent early alcohol use capitalizes on the influence of providers, immunization timing, and pediatric guidelines…
- Conditions
- Alcohol Drinking, Adolescent, Drinking Behavior, Drinking, Alcohol, Adolescent Behavior
- Trial name
- NCT05520333
- Testing
- BIPAS Alcohol
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol Drinking
Implementing Mobile Technology for Unhealthy Alcohol Use
Scalable approaches are needed to support patients identified in the emergency department as unhealthy alcohol users and text messaging intervention approaches are a promising solution.
- Trial name
- NCT05350878
- Testing
- Implementation Intervention
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- UConn Health
Major Depressive Disorder, Alcohol Use Disorder
Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial
Recent reports have shown that alcohol misuse is a particularly serious problem among the 18 to 25 year old age group. Previous medication trials with SSRI antidepressants among young adults with co-occurring depressive…
- Trial name
- YAAD-P (NCT02646449)
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alcohol Use Disorder
Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)
This study will evaluate the behavioral effects of alcohol during maintenance on placebo, duloxetine, methylphenidate and duloxetine combined with methylphenidate using sophisticated human laboratory methods.
- Trial name
- BED[IN]:36 (NCT03575403)
- Testing
- Alcohol, Duloxetine (60 MG), Methylphenidate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Craig Rush
Alcohol Use Disorder (AUD), Substance Use Disorders
The Anchor Study: Digitally Delivered Intervention for Reducing Problematic Substance Use
This study aims to validate W-SUDs as a digitally-delivered substance use disorder program through a fully-powered randomized control trial that will test the comparative efficacy of the mobile-app based substance use disorder…
- Trial name
- NCT04925570
- Testing
- W-SUDs, Digitally-delivered Psychoeducation
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Woebot Health
Human Immunodeficiency Virus (HIV)
Alcohol Monitor Validation
This study will validate a wrist-worn alcohol monitor (BACtrack Skyn) in both laboratory and real-life settings.
- Trial name
- NCT03617705
- Testing
- Skyn Monitor Lab Session 1, Skyn Monitor Field Test with EMA App, Skyn Monitor Lab Session 2
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol-related Disorders, Post-traumatic Stress Disorder
Couple-Based Treatment for Alcohol Use Disorders and Post-Traumatic Stress Disorder
The purpose of this study is to develop and test a couple-based treatment for Veterans with an alcohol use disorder and post-traumatic stress disorder.
- Trial name
- CTAP (NCT00946322)
- Testing
- Couple-Based Treatment for Alcohol Use Disorders and PTSD
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- VA Office of Research and Development
Alcohol Use, Unspecified
Estradiol Effects on Alcohol Across the Menstrual Cycle
This study will provide the first rigorous integrative test of the hypothesis that rapid rises in estradiol (a female hormone) increase the rewarding and disinhibiting effects of alcohol and that such increased sensitivity…
- Trial name
- NCT04595682
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mark Fillmore
Alcohol Consumption
Kudzu Treatment for Alcohol Abuse
This is a study designed to test whether a single administration of kudzu extract (2 mg) will significantly reduce the number of drinks consumed during a single 1 ½ hours drinking session when given as pretreatment 2 ½ hours…
- Trial name
- KUDZU (NCT01596231)
- Testing
- Kudzu
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Alcohol Use Disorder (AUD)
Records for Alcohol Care Enhancement
Unhealthy alcohol use (the spectrum from risky consumption through alcohol use disorder, AUD) is a leading cause of preventable death in the US (88,424 deaths annually costing $249 billion a year), and alcohol-related health…
- Trial name
- RACE (NCT05492942)
- Testing
- Best Practice Advisory (BPA) and Population Health Management (PHM), Best Practice Advisory (BPA) and Clinical Care Management (CCM), Best Practice Advisory (BPA) and Population Health Management (PHM) and Clinical Care Management (CCM)
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Hazardous Alcohol Use
PrEP and Alcohol - Enhancing HIV Pre-Exposure Prophylaxis (PrEP)
The present investigation entails a pilot randomized controlled trial to explore whether a stand-alone, alcohol-reduction, brief intervention (with a module on substance use and depression) would be feasible, acceptable, and…
- Trial name
- NCT05097430
- Testing
- Alcohol-focused brief intervention
- Where
- 3 sites in Canada
- Volunteers
- 122 people
- Sponsor
- Centre for Addiction and Mental Health
Primary Alcohol Use Disorder
Ketamine for Reduction of Alcoholic Relapse
96 recently detoxified alcoholics will be randomized to receive either 3 sessions ketamine (0.8 mg/kg IV over 45 minutes) or placebo plus manualised psychological therapy, or 3 sessions of ketamine or placebo plus simple…
- Trial name
- KARE (NCT02649231)
- Testing
- Ketamine, Psychological Therapy, Alcohol Education
- Where
- 2 sites in United Kingdom
- Volunteers
- 96 people
- Sponsor
- University College, London
Alcohol Consumption
Pilot Study of a Computer-Based Intervention for Alcohol Misuse in the Emergency Department
Alcohol misuse amongst youth is a significant clinical and public health problem. The Emergency Department (ED) is an important setting for the treatment of alcohol-related problems as it is often the first point of contact…
- Trial name
- NCT01146665
- Testing
- Computer-based PAF
- Where
- 3 sites in Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cancer, Alcohol Use
Evaluating an mHealth Intervention for Reducing Alcohol Use Among Adolescent and Young Adult Cancer Survivors
The objective of this study is to adapt and test the feasibility of a 4-week motivational interviewing mHealth intervention, Tracking and Reducing Alcohol Consumption (TRAC), to reduce alcohol use among adolescent and young adult…
- Trial name
- NCT05087875
- Testing
- TRAC: Tracking and Reducing Alcohol Consumption, No intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Carolyn Lauckner
Mental Health Issue, Alcohol Use Disorder
Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals
The current study aims to assess the acceptability and feasibility of an adapted version of Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS) for use with signing Deaf adults.
- Conditions
- Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- NCT05520190
- Testing
- Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Rochester
Alcohol Use Disorder, Post Traumatic Stress Disorder
Stress, Emotion Regulation, and Alcohol in Women Veterans
The purpose of the study "Stress, Emotion Regulation, and Alcohol in Women Veterans" is to learn about the effects of negative emotion and stress on behavior (including alcohol use) among women Veterans, including women with and…
- Trial name
- SERA (NCT04393623)
- Testing
- Cognitive Reappraisal, Psychoeducation
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Alcohol Drinking
Neural and Behavioral Effects of Cognitive Bias Modification (CBM)
This study seeks to better understand mechanisms of behavior change for heavy drinkers who are interested in changing their drinking.
- Trial name
- NCT04430543
- Testing
- Cognitive Bias Modification
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston University Charles River Campus
Oral Cancer, Esophageal Cancer
Evaluations of Alcohol Warning Labels
The goal of this study is to determine the effectiveness of pictorial warning labels (PWLs) featuring narrative (vs. non-narrative) content in communicating the cancer risk of alcohol.
- Conditions
- Oral Cancer, Esophageal Cancer, Larynx Cancer, Alcohol Drinking
- Trial name
- NCT06129487
- Testing
- Narrative pictorial warning labels for alcoholic beverages, Non-narrative pictorial warning labels for alcoholic beverages
- Where
- United States
- Volunteers
- 1,053 people, healthy volunteers welcome
- Sponsor
- University of Connecticut