Clinical trials: Drinking
Chronic Underhydration, Thirst; Due to Deprivation of Water
Effects of Habitual Water Intake on Thirst in Healthy Young Adults Explained by Osmoadaptive Metabolism, Brain and Kidney Function (Adapt-Thirst)
Social relevance: For 30 years, people have been confused about how much plain water to drink. Over 30 years, health professionals have criticized media advice to drink 8 glasses of water per day, citing lack of evidence (Valtin…
- Conditions
- Chronic Underhydration, Thirst; Due to Deprivation of Water, Aestivation Metabolism, Warburg Effect
- Trial name
- Adapt-Thirst (NCT07464002)
- Testing
- Drinking water to dilute urine
- Volunteers
- 120 people
- Sponsor
- Jodi Stookey
Alcohol Use Disorder, Alcohol Abstinence
Feasibility of Telephone-based Acceptance and Commitment Therapy in Hong Kong Chinese Young Adults With Alcohol Use Disorder: A Pilot Study
Objective: The proposed study aims to develop a protocol of telephone-based Acceptance and Commitment Therapy (ACT) for Alcohol Use Disorder (AUD) and examine the feasibility of implementing such intervention among the Hong Kong…
- Trial name
- NCT07501130
- Testing
- ACT, Social support
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Alcohol Consumption
A Social Media Personalized Normative Feedback Intervention for Heavy Drinking College Students
This study seeks to evaluate the unique and synergistic efficacy of social media-specific personalized normative feedback targeting the reduction of alcohol use among heavy-drinking college students who post alcohol-related…
- Trial name
- SMASH (NCT05608109)
- Testing
- Alcohol personalized normative feedback (APNF), Social media personalized normative feedback (SMPNF)
- Where
- 3 sites in United States
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Tuberculosis, HIV
Alcohol Reduction Among People With TB and HIV in India
The highest incidence of tuberculosis disease (TB) in the world is in India, accounting for 27% of all new cases globally, with approximately 86,000 among persons with HIV (PWH).
- Trial name
- HATHI (NCT04230395)
- Testing
- HATHI Intervention, Usual Care
- Where
- 2 sites in India
- Volunteers
- 450 people
- Sponsor
- Johns Hopkins University
Alcohol Use Disorder
Considering Healthier Drinking Options in Collaborative Care
The purpose of this study is to evaluate the effectiveness of a collaborative care intervention for evidence based management of alcohol use disorders in primary care settings within the Veterans Administration Puget Sound Health…
- Trial name
- CHOICE (NCT01400581)
- Testing
- Collaborative Care Intervention
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Alcohol Consumption
Kudzu Treatment for Alcohol Abuse
This is a study designed to test whether a single administration of kudzu extract (2 mg) will significantly reduce the number of drinks consumed during a single 1 ½ hours drinking session when given as pretreatment 2 ½ hours…
- Trial name
- KUDZU (NCT01596231)
- Testing
- Kudzu
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Alcohol Consumption, Hazardous Alcohol Consumption
Randomized Controlled Trial of a Minimal Versus Extended Internet-based Intervention for Problem Drinkers
Alcohol is one of the leading contributors to premature mortality and disability. Most people with alcohol problems will never seek treatment.
- Trial name
- NCT01874509
- Testing
- Check Your Drinking, Alcohol Help Centre
- Where
- Canada
- Volunteers
- 490 people
- Sponsor
- Centre for Addiction and Mental Health
Anesthesia, Spinal, Sedation, Conscious
Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
1. Adequate sedation with classical sedative agents, propofol 2. Sedation with propofol may induce paradoxical excitement response in heavy alcohol drinkers 3.
- Conditions
- Anesthesia, Spinal, Sedation, Conscious, Dexmedetomidine, Alcohol Drinking
- Trial name
- DEX (NCT02197403)
- Testing
- Dexmedetomidine, Propofol
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Chonnam National University Hospital
Diarrhea, Gastrointestinal Infection
Wells and Enteric Disease Transmission
Approximately 40 million people in the US are served by private, and frequently untreated, wells. Our best estimate is that 1.3 million cases of gastrointestinal illnesses (GI) per year are attributed to consuming water from…
- Conditions
- Diarrhea, Gastrointestinal Infection, Respiratory Viral Infection, Waterborne Diseases
- Trial name
- WET (NCT04826991)
- Testing
- Active UV Device, Inactive UV Device
- Where
- United States
- Volunteers
- 908 people, healthy volunteers welcome
- Sponsor
- Temple University
Cigarette Use, Alcohol Use Above Recommended Limits
Developing a Team-Delivered Intervention for Smoking and Hazardous Drinking for Primary Care Veterans With Cardiovascular Diseases
In this study, the investigators are interested in learning how patients feel about and are impacted by a new approach for the primary care team to use to talk to patients about heart disease and health behaviors.
- Conditions
- Cigarette Use, Alcohol Use Above Recommended Limits, Cardiovascular Risk Factors (e.g., Hypertension), Cardiovascular Diseases
- Trial name
- CARE (NCT05275582)
- Testing
- CARE
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alcoholic Intoxication
Alcohol Myopia, Objectification, and Sexual Assault
The present project integrates previous research on factors associated with alcohol-involved sexual assault, with research on how intoxication alters attention and social perceptions in ways that increase the risk of sexual…
- Trial name
- NCT03956238
- Testing
- Alcohol intoxication, Objectification
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Alcohol Drinking
Topiramate's Effects on Heavy Drinking
The proposed project will utilize perfusion functional magnetic resonance imaging (fMRI) to examine the effects of topiramate on brain and behavioral responses in heavy drinkers to appetitive alcohol reminders (cues that motivate…
- Trial name
- TOPMRI (NCT02074904)
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Pennsylvania
Healthy, Alcohol Drinking
Hangover and Residual Zopiclone Effect on Spatial Perception
Hangover after recreational alcohol use, residual effect of zopiclone and placebo compared in terms of spatial perception, psychomotor tests and simulated driving ability. Three recording visits plus screening included.
- Trial name
- SEKO-A (NCT03632408)
- Testing
- Zopiclone, hangover
- Where
- Finland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Petri Vainio
Alcohol Drinking, Alcohol Intoxication
Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving
This project aims to demonstrate the feasibility of a scalable behavioral intervention using smartphone-paired breathalyzers and text message aimed at reducing drinking and driving among individuals who report heavy drinking.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive
- Trial name
- BESAFE (NCT03335735)
- Testing
- Loss-framed text message, Gain-Framed text message
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Binge Drinking, Alcohol Drinking
Alcohol Consumption: Norms, Identities, & Motivations
The emergence of new problematic alcohol consumption practices among young people requires new dynamics in prevention strategies.
- Trial name
- ALCONIM (NCT06447350)
- Testing
- Induced hypocrisy, social identity mapping, Motivational modeling
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Alcohol Drinking
Digital Motivational Behavioral Economic Intervention to Reduce Risky Drinking Among Community-Dwelling Emerging Adults
Emerging adult risky drinkers living in disadvantaged communities often have limited access to rewarding activities and adult roles that offer alternatives to heavy drinking.
- Trial name
- Horizons (NCT05443750)
- Testing
- Motivational Behavioral Economic Alcohol Intervention, Health Education
- Where
- United States
- Volunteers
- 806 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Drinking
Engaging General Practice in the Prevention of Patients With Alcohol Problems
The aim of the study is to test whether or not a tailored multi-component intervention program to increase the activity of general practice teams in the prevention of hazardous and harmful alcohol consumption results in increase…
- Trial name
- NCT00298220
- Testing
- Feedback about patients at risk, Dissemination guideline and patient information letters, Tailored educational training
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Smoking Cessation, Alcohol Consumption
Smoking Cessation in Alcoholics
Most alcohol-dependent individuals are heavy smokers. The aim of this study is to evaluate whether a specific smoking cessation program (based on cognitive-behavioral therapy) for inpatient alcohol-dependent smokers is more…
- Trial name
- NCT00963482
- Testing
- Cognitive-behavioural smoking cessation program, Autogenic training
- Where
- Switzerland
- Volunteers
- 103 people
- Sponsor
- University Hospital, Basel, Switzerland
Memory Loss (Excluding Dementia), Lifestyle (Sedentary Behavior and Physical Activity)
Pilot Study of a Brain Health Program in Senior Centers
The investigators will evaluate a brain health programs in older adults with subjective cognitive decline. The primary aim of the study is to determine the credibility, expectancy, feasibility, acceptability, appropriateness…
- Conditions
- Memory Loss (Excluding Dementia), Lifestyle (Sedentary Behavior and Physical Activity), Lifestyle Risk Reduction, Healthy Lifestyle Behaviors
- Trial name
- NCT07424443
- Testing
- My Healthy Brain
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Alcohol Drinking, Cigarette Smoking Toxicity
Reduced Nicotine Cigarettes in Smokers With and Without Alcohol Use Disorder
The proposed research will investigate whether smokers with vs. without current at-risk alcohol drinking (ARD) respond to reduced nicotine cigarettes by increasing their alcohol consumption or smoke exposure, thereby diminishing…
- Trial name
- RedNic (NCT02990455)
- Testing
- Reduced nicotine cigarettes
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Battelle Memorial Institute