Clinical trials: Drinking Heavy
Alcohol Dependence
Use of Selincro and Impact on Usual Practice
USE-PACT is a cohort study of patients initiating Selincro® with one-year follow-up, performed using a random sample of prescribers.
- Trial name
- USE-PACT (NCT02492581)
- Testing
- Nalmefene
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University of Bordeaux
Alcohol Consumption
Evaluating the Efficacy of a Brief Online Intervention Among Current Heavy Drinkers
Unhealthy alcohol consumption is common in the UK and causes tremendous harm to the individual, as well as harm to others. A significant gap in providing alcohol support is that most people with unhealthy alcohol consumption will…
- Trial name
- NCT05767567
- Testing
- Brief Check Your Drinking (CYD)
- Where
- United Kingdom
- Volunteers
- 867 people
- Sponsor
- King's College London
Alcohol Drinking
Varenicline to Reduce Alcohol Consumption in Heavy Drinkers
This study will determine whether varenicline, a drug that acts on the brain's nicotine receptors and is used to help smokers stop smoking, will have an impact on alcohol self-administration.
- Trial name
- NCT00695500
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vijay Ramchandani, Ph.D.
Alcohol Consumption
Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling
The main purpose of this study is to see whether heavy drinking will interfere with a specific pathway, called FXR signaling in the liver.
- Trial name
- NCT02654236
- Testing
- 10 mg Obeticholic Acid (OCA)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suthat Liangpunsakul
Alcohol Drinking, HIV
Behavioral Interventions to Reduce Heavy Drinking Among MSM in HIV Primary Care
The purpose of the present study is to conduct a fully-crossed 2 X 2 X 2 factorial randomized controlled trial with a diverse sample of 224 MSM recruited from 2 urban HIV primary care clinics (one in the Northeast and one in the…
- Trial name
- NCT02709759
- Testing
- Motivational intervention, Brief Advice, Interactive text messaging
- Where
- 2 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Drinking, Alcohol Use Disorder
Effect of Theta Burst Stimulation on Alcohol Cue Reactivity
Alcohol Use Disorder (AUD) is prevalent, devastating, and difficult to treat. The intransigence of AUD is readily apparent in the Trauma Unit of Wake Forest University Baptist Hospital, wherein 23% of trauma related admissions…
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence
- Trial name
- NCT04223154
- Testing
- Real iTBS to the dlPFC
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wake Forest University Health Sciences
Alcohol Use Disorder, Alcoholism
Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)
The study will compare alcohol use in two groups of subjects. One group will be assigned to the Deep TMS treatment and the other group will be assigned to the sham treatment.
- Conditions
- Alcohol Use Disorder, Alcoholism, Alcohol Abuse, Alcohol Dependence
- Trial name
- NCT07216872
- Testing
- Deep TMS (DTMS)
- Where
- 11 sites in United States, Israel and 1 more
- Volunteers
- 186 people
- Sponsor
- Brainsway
Alcohol Use Disorder
The Effects of Exenatide, a GLP-1 Agonist, on Alcohol Self-Administration in Heavy Drinkers
A double-blind, randomized, placebo-controlled, crossover design trial was used to test the effect of exenatide on alcohol self-administration and craving following a priming dose of alcohol.
- Trial name
- NCT03645408
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Drinking, College, Drinking Heavy
College Student Daily Life and Alcohol Use Study
Heavy alcohol use among college students is associated with a range of negative consequences. However, college students rarely seek resources or treatment to change their alcohol use.
- Trial name
- NCT06365125
- Testing
- eCHECKUP TO GO, Text messaging boosters
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Binge Eating, Binge Drinking
Brief Binge Eating and Drinking Online Intervention
This pilot project targets both binge drinking and binge eating behavior in college students through a mobile-based online program that provides students with evidence-based intervention material designed to reduce the incidence…
- Trial name
- NCT06326099
- Testing
- Brief Online Binge Eating and Drinking Intervention
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Alcohol-related Disorders, Drinking and Driving
Evaluation of an School-based Alcohol Prevention Program for Middle School Students
The purpose of this research is to create and evaluate the efficacy of an exciting (fun to use), and potentially disseminable computer-based prevention program, Click City®: Alcohol, for use by 7th graders with a booster in 8th…
- Conditions
- Alcohol-related Disorders, Drinking and Driving, Neurological Impairment
- Trial name
- AlcoholINET (NCT01847183)
- Testing
- Click City®: Alcohol
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- Oregon Research Institute
Alcohol Drinking, Alcohol Use Disorder
Understanding Alcohol Reward in Social Context
In this study, the investigators examine whether emotional and social reward from alcohol varies depending on the social context of consumption.
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use
- Trial name
- NCT03449095
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Heavy Episodic Drinking
Understanding the Associations Between Romantic Relationship Conflict, Psychophysiological Responding and Alcohol Misuse Among Emerging Adults
Emerging Adults (EA) engage in heavy episodic drinking (HED) at a greater quantity and frequency than any other time in their lives, which may lead to significant short- and long-term consequences.
- Trial name
- NCT06976528
- Testing
- Alcohol administration
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- New York University
Binge Drinking, Heavy Drinking
Alcohol-ROC-Training
The goal of the proposed study is to examine whether brief training in regulation of craving (ROC-T) affects alcohol drinking. The study will consist of a basic screening (phone and online), and in person visit to determine…
- Conditions
- Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
- Trial name
- A-ROC-T (NCT05491551)
- Testing
- Mindfulness-Based Treatment-Regulation of Craving, Cognitive-Based Therapy-Regulation of Craving
- Where
- 2 sites in United States
- Volunteers
- 177 people
- Sponsor
- Yale University
Alcohol Use Disorder, Alcohol Drinking
Virtual Incentive Treatment for Alcohol
The overall objective of this program of research is to utilize phosphatidylethanol (PEth), a blood-based biomarker that can detect alcohol use for up to 28 days to deliver a feasible telehealth-based 26-week CM intervention.
- Conditions
- Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
- Trial name
- VITA (NCT06265506)
- Testing
- Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Washington State University
Alcohol-Related Disorders, Alcohol Use Disorders
Adaptive Interventions for Problem Drinkers
The purpose of this study is to understand how certain interventions help people reduce or quit their drinking and how certain interventions may help best at certain points in time in the change process.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT02511808
- Testing
- Brief Advice, Motivational Interviewing, Behavioral Self-Control Training
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Northwell Health
Heavy Drinking, Alcohol Drinking
A Brief Intervention for Alcohol Users With Interpersonal Trauma
The current proposal aims to enhance a mobile-delivered brief intervention for young adults with heavy alcohol use and interpersonal trauma by including adaptive coping strategies for managing trauma-related distress and using…
- Conditions
- Heavy Drinking, Alcohol Drinking, Substance Use, Drinking Behavior
- Trial name
- NCT05414344
- Testing
- Standard Brief Intervention, Trauma-Informed and Peer-Supported Brief Intervention, Assessment only
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- Western Kentucky University
Tobacco Dependence, Alcohol Dependence
Effect of Varenicline on Reactivity to Smoking and Drinking Cues
Alcohol and nicotine dependence are often co-morbid, with 85% of alcoholics also smoking. However, very little research has been conducted into the nature of this co-occurrence.
- Trial name
- NCT00873535
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
HIV Infections, Alcoholism
Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women
The purpose of this study is to determine whether two brief counseling sessions reduce drinking and improve health outcomes in HIV-positive women who drink at heavy/hazardous levels.
- Trial name
- NCT00127231
- Testing
- Brief alcohol intervention based on Project Treat, Standard care
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Johns Hopkins University
Alcohol Use Disorder
Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers
This is a double-blind, randomized, placebo-controlled, crossover design trial tested the effect of lacosamide on alcohol self-administration and craving following a priming dose of alcohol.
- Trial name
- NCT03271528
- Testing
- Lacosamide
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Boston Medical Center