Clinical trials: Drinking Heavy
Alcohol Use Disorder, Mild-Moderate Traumatic Brain Injury
Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain Injury
The project will examine the neural associations of alcohol approach-bias and investigate the extent to which a neuroscience-based personalized cognitive training program will remediate alcohol approach-bias and improve recovery…
- Trial name
- TABM (NCT06380985)
- Testing
- Personalized VR Alcohol Approach Bias Modification (ApBM) Condition
- Where
- United States
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder
Pilot Study: Effects of Nimodipine on Alcohol Drinking
This is an open label trial aiming to recruit 5 non-treatment seeking adults with Alcohol Use Disorder. All will participate in an alcohol drinking paradigm (ADP) lab session at the Hospital Research Unit (HRU) at Yale-New Haven…
- Trial name
- NCT06900998
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Alcohol Abuse, Alcohol Dependence
Use of Kudzu Extract in the Study of Its Ability to Reduce Alcohol Drinking in Treatment Seeking Alcohol Dependent Persons
This research is designed to assess if problem drinking by treatment seeking individuals can be treated (reduced) by kudzu extract pharmacotherapy plus medical management therapy.
- Conditions
- Alcohol Abuse, Alcohol Dependence, Heavy Drinking Days
- Trial name
- NCT01853293
- Testing
- Kudzu extract, Medical Management
- Where
- United States
- Sponsor
- Mclean Hospital
Alcoholism
Varenicline for Alcohol Dependence
The primary objective of this study is to assess the efficacy of varenicline in reducing the proportion of heavy drinking days during the last 8 weeks of treatment in subjects with alcohol dependence confirmed by Diagnostic and…
- Trial name
- NCIG 003 (NCT01146613)
- Testing
- Varenicline
- Where
- 7 sites in United States
- Volunteers
- 200 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Drinking
Topiramate's Effects on Heavy Drinking
The proposed project will utilize perfusion functional magnetic resonance imaging (fMRI) to examine the effects of topiramate on brain and behavioral responses in heavy drinkers to appetitive alcohol reminders (cues that motivate…
- Trial name
- TOPMRI (NCT02074904)
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Pennsylvania
Alcohol Use Disorder
Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy
The purpose of this study is to evaluate the safety and efficacy of dutasteride in reducing drinking and heavy drinking in men and women with alcohol use disorder.
- Trial name
- NCT04098302
- Testing
- Dutasteride Capsules
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- UConn Health
Alcohol Use Disorder
INIA Stress and Chronic Alcohol Interactions: Glucocorticoid Antagonists in Heavy Drinkers
In alcohol use disorder (AUD) and matched healthy control (HC) men and women, the proposed research examines the effects of MIFE, with demonstrated preclinical effects on drinking-related behaviors, compared with placebo on a…
- Trial name
- NCT02989662
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cigarette Smoking, Alcohol Consumption
Effects of Varenicline in Heavy Drinking Smokers
This laboratory study will examine if varenicline can reduce alcohol-induced smoking lapse in heavy drinking smokers.
- Trial name
- VAR (NCT02488889)
- Testing
- Varenicline, Alcohol
- Where
- United States
- Sponsor
- University of California, Los Angeles
Sexual Aggression, Heavy Drinking
Emotion Regulation Interventions for Alcohol-Related Sexual Aggression
Rates of sexual assault are alarmingly high, and alcohol is consistently implicated in the majority of these assaults. Despite well-intentioned prevention efforts, this pandemic continues unabated, warranting the development of…
- Trial name
- NCT03159468
- Testing
- Cognitive Restructuring, Mindfulness, Alcohol consumption
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- University of Washington