Clinical trials: Driving
Alcohol Dependence
Study of Acamprosate in Driving Under the Influence (DUI) Court Participants
Acamprosate will be given to approximately 30 DUI Court participants for 3 months and outcomes will be monitored. The hypothesis is that acamprosate will be safe and well-tolerated and that subjects' craving and other symptoms…
- Trial name
- NCT00425711
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Oklahoma
Drunk Driving, Alcohol Drinking
Design and Evaluation of an In-Vehicle Real-Time Drunk Driving Detection System
To analyze driving behavior of individuals under the influence of alcohol while driving in a real car. Based on the in-vehicle variables, the investigators aim at establishing algorithms capable of discriminating sober and drunk…
- Conditions
- Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT05796609)
- Testing
- Driving under the influence of alcohol
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Driving Under the Influence
Combined and Separate Effects of Cannabis and Tobacco: Psychomotor, Subjective and Physiological Outcomes
Co-administration of cannabis and tobacco is a common practice, but there is little experimental evidence aimed at understanding the reasons for this prevalence.
- Trial name
- CASE-CT (NCT05526196)
- Testing
- Cannabis, Tobacco, Cannabis tobacco
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Driving Pressure, Neuromuscular Blockade Monitoring
Effect of Neuromuscular Block Depth on Driving Pressure and Postoperative Respiratory Events in Abdominal Surgeries
This randomized controlled study aims to evaluate the effects of deep versus moderate neuromuscular blockade on intraoperative driving pressure and the development of postoperative critical respiratory events in patients…
- Conditions
- Driving Pressure, Neuromuscular Blockade Monitoring, Postoperative Respiratory Complications
- Trial name
- NCT07464288
- Testing
- Rocuronium
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Driving Impaired
Validation of Alcohol Level Identification Using DRIVESC
This pilot study will evaluate the feasibility and acceptability of using a commercially available DRIVESC fitness-to-drive measurement tool to detect alcohol-induced impairment in healthy adult participants.
- Trial name
- NCT07282405
- Testing
- DRIVESC, Alcohol
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Driving Risk Factors Among Adolescents With ADHD
The Effectiveness of Cognitive-Functional Intervention to Reduce Driving Risk Factors of Adolescents With ADHD
Background: Attention deficit hyperactivity disorder (ADHD) is associated with a high risk for driving accidents. Adolescents with ADHD are 1.2 to 4 times more prone to be involved in car accidents.
- Trial name
- NCT05832957
- Testing
- Drive fun, educational intervention, No intervention
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications
Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications
The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure (ΔP), in…
- Conditions
- Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications, Postoperative Respiratory Failure, Postoperative Bronchospasm
- Trial name
- NCT07186933
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Impaired Driving
Assessing the Effectiveness of Screening, Brief Intervention, and Referral to Treatment (SBIRT) With Personalized Feedback Intervention to Reduce Polysubstance Impaired Driving in Young Adults Aged 18-30
The current study is assessing the effects of receiving Screening, Brief Intervention and Referral to Treatment alone versus also receiving a brief online personalized intervention on impaired driving behaviors among Washington…
- Trial name
- ADAPT (NCT07368894)
- Testing
- Personalize Feedback Intervention
- Volunteers
- 600 people
- Sponsor
- University of Washington
Driving Under the Influence of Cannabis
Pilot-Study for the Comparison of Biomarkers Between Regular Cannabis Users and Non-Users
The relevance of driving under the influence of cannabis is becoming increasingly important in the context of legalization. However, the measurement of tetrahydrocannabinol (THC) blood concentration is an inadequate marker for…
- Trial name
- CANBiome (NCT06975020)
- Testing
- Participants will prepare their cannabis product ad libitum and inhale the prepared product as usual for a maximum of 15 minutes.
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Basel
Minor Surgical Procedures With Monitored Anesthesia Care, Driving Performance After Minor Ambulatory Surgery
Safety of Driving After Minor Surgery With Monitored Anesthesia Care
Patients are currently advised to refrain from driving motor vehicles or using public transportation unescorted for a 24 hour period if they undergo any minor ambulatory surgical procedure with monitored anesthesia care…
- Trial name
- MACDrive (NCT00577200)
- Testing
- Midazolam, Sufentanil, Propofol
- Where
- United States
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
MIBC, mpMRI
Early Prediction of Neoadjuvant Chemotherapy Response in Bladder Cancer Using Quantitative Multiparametric MRI
Bladder cancer is a prevalent malignancy globally, with muscle-invasive disease having a five-year survival rate below 50%. Neoadjuvant chemotherapy (NAC) before radical cystectomy has shown efficacy for resectable…
- Conditions
- MIBC, mpMRI, NAC
- Trial name
- mpMRI (NCT07202845)
- Testing
- Multiparametric Magnetic Resonance Imaging (mpMRI)
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Assiut University
Binge Drinking, Underage Drinking, Drinking and Driving, Alcohol-Related Harms
Evaluation of Global Smart Drinking Goals Initiative
This study will evaluate effects of a multi-component, population-level intervention on alcohol use and related harms in six intervention cities relative to six matched comparison cities.
- Trial name
- GSDG (NCT03262259)
- Testing
- GSDG multi-component intervention
- Where
- United States
- Volunteers
- 36,000 people, healthy volunteers welcome
- Sponsor
- HBSA
Alcohol-Impaired Driving
An Interactive Text-Message Based Brief Intervention to Reduce Substance-Impaired Driving Among College Students
Substance-Impaired Driving among college students remains a significant public health concern and may be the single riskiest substance-related outcome among young adults.
- Trial name
- NCT03496129
- Testing
- Personalized feedback, Personalized feedback and text messages, Information Only
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
Cannabis, Driving Under the Influence
Cannabis Edibles and Simulated Driving
The goal of this human laboratory experiment is to determine the acute and residual effects of a range of doses of orally administered cannabis edibles on driving simulator performance in people who use cannabis recreationally.
- Trial name
- NCT06595576
- Testing
- Cannabis - Low Dose (2 mg), Cannabis - Medium Dose (10 mg), Cannabis - High Dose (20 mg)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Mechanical Ventilation, Lung Protective Ventilation
Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries
Patient undergoing surgeries in general anesthesia require support of their breathing by ventilator. Different strategies can be used to manage breathing of the patient.
- Conditions
- Mechanical Ventilation, Lung Protective Ventilation, Driving Pressure
- Trial name
- NCT07092943
- Testing
- Lung protective ventilation, Driving pressure guided ventilation
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Driving Pressure, Positive End-expiratory Pressure
Driving Pressure-guided Positive End-expiratory Pressure to Prevent Postoperative Atelectasis in Obese Children: a Prospective, Randomized Controlled Clinical Trial
At present, the use of lung protective ventilation strategies in children is mainly based on adult and intensive care unit data.
- Conditions
- Driving Pressure, Positive End-expiratory Pressure, Postoperative Atelectasis, Obese
- Trial name
- NCT06471491
- Testing
- Driving pressure-guided positive end-expiratory pressure
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Henan Provincial People's Hospital
Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA)
Validating a Novel Driving Simulation-based MWT Against the Standard MWT in an OSA-cohort Challenged by CPAP-withdrawal
In brief, the proposed study will evaluate a recently proposed naturalistic, driving simulation test to identify and measure sleepiness behind the wheel, one of the most underestimated causes of road accidents.
- Conditions
- Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA), CPAP Treatment, Driving Simulator Performance
- Trial name
- DS-MWT2 (NCT06872593)
- Testing
- CPAP-withdrawal, Test Sequence
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Stefan Lakämper
Driving Pressure
Driving Pressure Guided Ventilation Versus Conventional Lung Protective Strategy in Morbid Obese Patients Undergoing Laparoscopic Bariatric Surgery
This study will be conducted to evaluate the effect of driving pressure guided ventilation compared with conventional protective lung ventilation during laparoscopic bariatric surgeries in morbid obese patients.
- Trial name
- NCT04861168
- Testing
- driving pressure guided ventilation, Conventional protective lung strategy
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Distracted Driving, Injury Prevention
A Randomized Field Trial of Smartphone-based Feedback to Encourage Safe Driving
The study team are proposing to conduct a randomized controlled trial to determine the effectiveness of focused feedback vs standard feedback and self-chosen vs assigned goals on driving behaviors targeted by behavior-based…
- Conditions
- Distracted Driving, Injury Prevention, Behavioral Economics
- Trial name
- NCT06101251
- Testing
- Driving Tips, Standard Feedback, Assigned Focus Area Feedback
- Where
- United States
- Volunteers
- 1,449 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
ADHD - Attention Deficit Disorder With Hyperactivity, Driving Simulator Performance
Exploring Parameters of Driving Simulation in Relation to Drug Holidays in ADHD Patients
Attention deficit hyperactivity disorder (ADHD) or syndrome (ADHS) is a symptomatically defined condition that - if untreated - is linked to a significantly increased risk of traffic accidents.
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Driving Simulator Performance, ADHD, Driving Behavior
- Trial name
- DS-ADHD1 (NCT06910605)
- Testing
- "drug holidays" (D)
- Where
- Switzerland
- Volunteers
- 26 people
- Sponsor
- Stefan Lakämper