Clinical trials: Driving
Acute Respiratory Distress Syndrome, Pneumonia
The Relationship Between Driving Pressure, Mechanical Power, Oxygenation and Saturation Indices: Retrospective Observational Study
By using Mechanical Power and Driving Pressure instead of Pmean we calculate new oxygen saturation indices like Driving Pressure Oxygen Index (OIDP), Dynamic Power Oxygen Index (OIMPdyn), Total Power Oxygen Index (OIMPtot)…
- Trial name
- NCT05677165
- Where
- Turkey (Türkiye)
- Volunteers
- 361 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Cannabis, Alcohol Effect
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
- Conditions
- Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
- Trial name
- THC-ETOH-III (NCT02710331)
- Testing
- Active Dronabinol, Active Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Mild Cognitive Impairment
Improving Performance in Drivers With Mild Cognitive Impairment
The objective of this study is to assess the effectiveness of an intervention to address both executive function and processing speed changes that contribute to poor driving performance in adults with Mild Cognitive Impairment…
- Trial name
- NCT01935219
- Testing
- Goal Management Training, Processing Speed Training, Brain Health Workshop
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- Baycrest
Depressive Disorder, Major
A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder
The purpose of the study is to evaluate the effect of seltorexant, compared to placebo, as an add-on medication to an antidepressant, on next-day driving performance as assessed by the mean difference of standard deviation of…
- Trial name
- NCT04451187
- Testing
- Seltorexant Dose 1, Seltorexant Dose 2, Zopiclone
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Alcoholism
Effects of Alcohol on Simulated Driving
Previous studies have shown that alcohol significantly impairs driving performance. Acute alcohol administration also has a detrimental effect on secondary task performance during dual-tasks.
- Trial name
- NCT00477984
- Testing
- alcohol
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
One-Lung Ventilation, Postoperative Respiratory Complications
Driving Pressure and Postoperative Pulmonary Complications
This study aims to prove that driving pressure limited ventilation is superior in preventing postoperative pulmonary complications to existing protective ventilation.
- Conditions
- One-Lung Ventilation, Postoperative Respiratory Complications, Driving Pressure
- Trial name
- NCT02851238
- Testing
- Driving Pressure Limited Ventilation
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- Samsung Medical Center
Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications
Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications
The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure (ΔP), in…
- Conditions
- Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications, Postoperative Respiratory Failure, Postoperative Bronchospasm
- Trial name
- NCT07186933
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Driving, Intoxication
Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving
The proposed study will validate and determine sensitivity of our new driving simulator, created to evaluate driving ability in a related study to show similar driving performance between patients on chronic opioid treatment and…
- Conditions
- Driving, Intoxication, Impairment, Alcohol Impaired Driving
- Trial name
- ALCDrive (NCT00559819)
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Attention Deficit Hyperactivity Disorder
A Study of SPD465 in Young Adult Drivers With Attention-Deficit Hyperactivity Disorder (ADHD) Using Driving Simulators
The purpose of this study is to determine whether SPD465 is safe and effective in the treatment of ADHD in young adult drivers after a duration of 16 hours.
- Trial name
- NCT00458445
- Testing
- SPD465
- Where
- United States
- Sponsor
- Shire
Validity, Distracted Driving
Way To Drive Validation Study
Way to Drive is a smart phone-based driving telematics application. Research participants are invited to download the app, which uses phone sensors to track driving behaviors including mileage, hard breaking events, and handheld…
- Conditions
- Validity, Distracted Driving, Driving Behaviors
- Trial name
- NCT05422586
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Pennsylvania
Macular Degeneration
Evaluation of Visual Function and Driving Health Using Ocusweep in Patients Suffering From Wet Age-related Macular Degeneration
The aim is to study the use of Ocusweep system especially in driving health evaluation and compare the results produced by Ocusweep system to those of conventional devices.
- Trial name
- NCT02747368
- Testing
- Ocusweep system
- Volunteers
- 600 people
- Sponsor
- Turku University Hospital
Automobile Driving With an Aircast Walker, Automobile Driving With a Walking Cast
Effects of Right Lower Limb Orthopedic Immobilization on Braking Function
Research on the implications of orthopedic injury and surgery on automobile driving ability has been limited. Only a handful of orthopedic issues have been studied to date, especially the safe postoperative resumption of driving.
- Trial name
- NCT01171287
- Testing
- Driving with an Aircast Walker, Driving with a walking cast, Driving with a running shoe
- Where
- 2 sites in Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Driving Impaired, Alcohol Intoxication
Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests
The overarching aim of this study is to examine the impact of acute cannabis and alcohol administration on driving performance, as well as identify methods for detecting driving under the influence of these substances.
- Conditions
- Driving Impaired, Alcohol Intoxication, Driving Under the Influence, Cannabis Intoxication
- Trial name
- NCT05273658
- Testing
- Cannabis, Alcohol
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Peripheral Pulmonary Nodules
Sd-RAB for the Diagnosis of PPNs
This is a single-center, prospective, and single-arm study. The purpose of this study is to evaluate the feasibility and safety of a new self-driving robotic-assisted bronchoscopic system for the diagnosis of peripheral pulmonary…
- Trial name
- NCT06719687
- Testing
- Self-driving robotic-assisted bronchoscope
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Chest Hospital
Healthy Participants
Development of Assessment Method for Driving Ability Using Driving Simulator in Healthy Volunteers #3
The purpose of this study is to collect alcohol calibration data for the driving simulator.
- Trial name
- NCT03572985
- Testing
- Road-tracking test, Car-following test, Harsh-braking test
- Where
- Japan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Cardiovascular Diseases
Reha Drive: Predictors of Fitness to Drive a Car for Cardiologic Patients and Determination of Vital Signs
In this study predictors of fitness to drive a car in cardiologic patients after acute intervention and discharge from hospital to home or rehabilitation are determined in addition to possible automotive monitoring of vital signs…
- Trial name
- RehaDrive (NCT02368158)
- Testing
- Driving simulation with elevation of medical data in comparison to Lane Change Test plus automotive monitoring via contactless sensors
- Where
- 2 sites in Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Choroidal Neovascularization Secondary to Pathologic Myopia
A Study of the Criteria Establishing the Need for Re-treatment With Ranibizumab Upon Relapse in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia.
The primary objective of the study was to investigate current criteria driving re-treatment in patients affected by Choroidal Neovascularization (CNV) secondary to Pathologic Myopia (PM) and experiencing a relapse of the disease…
- Trial name
- OLIMPIC (NCT02034006)
- Testing
- Ranibizumab
- Where
- 31 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Novartis Pharmaceuticals
ADHD - Attention Deficit Disorder With Hyperactivity
ADRIS Driving Simulator for Adolescents With Attention Deficit and Hyperactivity Disorder
This study aims to evaluate a new driving simulator, called ADRIS 2.1, developed for adolescents aged 13-18 years with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- ADRIS-ADHD (NCT07478458)
- Testing
- ADRIS-ADHD
- Where
- 2 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istituto Giannina Gaslini
Multiple Sclerosis
Effect of Interferon Beta-1a (Avonex®) on Changes of Non-conventional MRI Measures in Patients With MS
Phase IV open label, single-blind study, post-marketing, 1-year MRI observational study evaluating effect of Avonex® monotherapy (6.0 MIU administered i.m.
- Trial name
- NCT00463710
- Testing
- Avonex® monotherapy (6.0 MIU administered i.m. each week)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- State University of New York at Buffalo
Occasional (1-2 Joints Per Week) and Chronic (1-2 Joints Per Day) Cannabis Users
Study of the Relationship Between Dose-concentration-effect of Delta-9-tetrahydrocannabinol (THC) and the Ability to Drive in Chronic or Occasional Cannabis Users
Study of the effects of smoked cannabis consumption on performance on a driving simulator and reaction time. The study aims to explore the relationship between concentrations of cannabis in the blood, driving performance and…
- Trial name
- VIGICANN (NCT02061020)
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris