Clinical trials: Driving Impaired
Cataract, Traffic Accident
Validation of Mesopic and Photopic Contrast Vision Tests With Respect to Nighttime Driving Ability
A) The main purposes of this study are (i) to develop a related virtual reality (VR) environment in order to judge the nighttime driving ability under mesopic and under glare conditions (ophthalmologically healthy subjects and…
- Conditions
- Cataract, Traffic Accident, Vision Disorders, Driving Impaired
- Trial name
- ContrastVal (NCT03169855)
- Testing
- Slit lamp (LOCS III Score)
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Aalen University
Driving Under the Influence
Alcohol Impaired Driving in the Natural Environment
This is a pilot study to set up a larger investigation examining predictors of the decision to drive after consuming alcohol. All participants will carry a study provided smartphone and breathalyzer device for the 2 week period…
- Trial name
- NCT03503396
- Testing
- BAC Driving Feedback/Warning, No Feedback
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cannabis
Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance
Delta-8-THC is an isomer of delta-9-THC that has become widely available due to the legalization of hemp and its derivatives. Very little controlled research has been conducted with delta-8-THC and some research suggests it…
- Trial name
- NCT06218550
- Testing
- Delta-9-THC, Delta-8-THC
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Pain
Use of Driving Tests to Evaluate Patient Performance on Oral Opioids
Many patients seen at Pain Centers are advised not to drive if they are on long-term opioid medications. Although such advice is routinely given considering patients' safety, unnecessary restrictions to driving can cause…
- Trial name
- OpDrive (NCT00659035)
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Asokumar Buvanendran
Roux-en-Y Gastric Bypass, Postprandial Hypoglycemia
Effect of Postprandial Hyperinsulinaemic Hypoglycaemia on Driving Performance.
The primary objective of this study is to assess the effect of the natural course of postprandial hypoglycemia vs. a postprandial euglycaemic condition on driving performance in individuals with confirmed postprandial…
- Conditions
- Roux-en-Y Gastric Bypass, Postprandial Hypoglycemia, Driving Impaired
- Trial name
- DEEP1C (NCT04330196)
- Testing
- Oral glucose tolerance test
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Lia Bally
Cannabis Intoxication
The Impact and Detection of Driving Impairments Associated With Acute Cannabis Smoking
This study was authorized by the California Legislature (Assembly Bill 266, the Medical Marijuana Regulation and Safety Act to help with detection of driving under the influence of cannabis.
- Trial name
- NCT02849587
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Driving Habits Patients, Cognitive Impairment
Evaluation of an Educational Program in the Prevention of the Driving Risks in Patients With Neurocognitive Disorders : ACCOMPAGNE
ACCOMPAGNE study proposes to evaluate an educational program for the patient / caregiver dyad, intended to accompany the patient towards the implementation of self-regulation strategies in the driving activity.
- Trial name
- ACCOMPAGNE (NCT04493957)
- Testing
- ACCOMPAGNE Education Program, Usuals recommandations
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Alcohol Drinking, Alcohol Intoxication
Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving
This project aims to demonstrate the feasibility of a scalable behavioral intervention using smartphone-paired breathalyzers and text message aimed at reducing drinking and driving among individuals who report heavy drinking.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive
- Trial name
- BESAFE (NCT03335735)
- Testing
- Loss-framed text message, Gain-Framed text message
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Impairment, Cognitive, Impairment of Attention
High Confusion: Cannabis & Driving
This study is being done to assess the feasibility of administrating Δ9-THC and Δ8-THC isolates and simultaneously adopting several data harmonization measures to generate uniquely translatable data.
- Conditions
- Impairment, Cognitive, Impairment of Attention, Impairment, Psychomotor
- Trial name
- NCT06236815
- Testing
- Delta-9-THC, Delta-8-THC
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cannabis Use, Impaired Driving
Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance
The purpose of this research is to determine the extent to which oculomotor function accurately detects THC-impairment, if cannabis use experience impacts this detection threshold, and to examine how the oculomotor index…
- Conditions
- Cannabis Use, Impaired Driving, Cognitive Impairment
- Trial name
- NCT06351540
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Drunk Driving, Alcohol Drinking
Design and Evaluation of an In-Vehicle Real-Time Drunk Driving Detection System
To analyze driving behavior of individuals under the influence of alcohol while driving in a real car. Based on the in-vehicle variables, the investigators aim at establishing algorithms capable of discriminating sober and drunk…
- Conditions
- Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT05796609)
- Testing
- Driving under the influence of alcohol
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Marijuana Impairment
Examine the Feasibility of a Standardized Field Test for Marijuana Impairment: Laboratory Evaluations
Marijuana is one of the most widely used substances. This study will characterize the persistence of cannabis' (CNB's) acute effects on cognitive test performance and simulated driving over a several hour time period.
- Trial name
- NCT03191084
- Testing
- Low Dose THC Marijuana, High Dose THC Marijuana
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Yale University
Driving Under the Influence
Whole Blood-plasma-oral Fluid Ratios of Psychoactive Drugs and Medicines
The aim of this study is to get new information on the whole blood-plasma-oral fluid ratios of psychoactive drugs which are encountered in traffic.
- Trial name
- NCT00650130
- Where
- Finland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Marijuana Impairment
Neuroscience of Marijuana Impaired Driving
Marijuana is one of the most widely used substances. However, marijuana intoxication is not fully understood in relation to driving.
- Trial name
- MJDriving (NCT02757313)
- Testing
- Low dose THC marijuana, High dose THC marijuana
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yale University
Impaired Driving
Assessing the Effectiveness of Screening, Brief Intervention, and Referral to Treatment (SBIRT) With Personalized Feedback Intervention to Reduce Polysubstance Impaired Driving in Young Adults Aged 18-30
The current study is assessing the effects of receiving Screening, Brief Intervention and Referral to Treatment alone versus also receiving a brief online personalized intervention on impaired driving behaviors among Washington…
- Trial name
- ADAPT (NCT07368894)
- Testing
- Personalize Feedback Intervention
- Volunteers
- 600 people
- Sponsor
- University of Washington
Driving Behavior, Driving Under the Influence
Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSim
Subjects will participate in a 4-visit study protocol at the National Advanced Driving Simulator, part of the University of Iowa, in which they will be asked to complete assorted questionnaires, computerized cognitive tasks, and…
- Trial name
- PDID (NCT04970342)
- Testing
- 0.75 mg Alprazolam Capsule, Cannabis (6.18% THC / <0.025% CBD), Cannabis (0%/ THC / 0% CBD)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Timothy L. Brown
Psychomotor Impairment
Sedative-Anxiolytic Effects on Simulated Driving Performance
This study evaluates the effect of anxiety drugs taken at night on the ability to drive a car the next day. Participants will receive alprazolam, placebo, or zolpidem at night before bed or in the morning before using a driving…
- Trial name
- NCT03297944
- Testing
- Alprazolam 2mg (2ALP/PLC), Alprazolam 1mg (1ALP/PLC), Alprazolam 0.5mg (0.5ALP/PLC)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marion Coe
Impaired Driving
Video Intervention to Enhance the Safety Of Cognitively Impaired Older Drivers
This pilot study was done to assess the feasibility and possible efficacy of a video feedback intervention to improve the safety of cognitively impaired older drivers.
- Trial name
- NCT02593552
- Testing
- DriveCam
- Volunteers
- 12 people
- Sponsor
- Rhode Island Hospital
Transportation Accidents, Drunk Driving
Design and Implementation of a Drunk Driving Detection System
To analyse driving behavior of individuals under the influence of alcohol using a validated research driving simulator. Based on the driving variables provided by the simulator the investigators aim at establishing algorithms…
- Conditions
- Transportation Accidents, Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT04980846)
- Testing
- Driving under the influence of alcohol with a driving simulator
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bern
Driving Impaired
Driving Performance After Deep Sedation for Outpatient Endoscopy
Many drugs used during anesthesia can reduce alertness and therefore present potential risks when driving a vehicle (risk of accident).
- Trial name
- NCT04948385
- Testing
- Propofol, No sedation
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Liege