Clinical trials: Driving Impaired
Ride Sharing, Alcohol Drinking
The Rise of Ride Sharing Companies and Trends in Impaired Driving Accidents
This will be a retrospective study with data collected from the trauma registry. We plan to complete the data collection and analysis by 12/31/2020. Data on ride sharing will be obtained from the Uber and Lyft websites.
- Conditions
- Ride Sharing, Alcohol Drinking, Alcohol Intoxication, Drug Use
- Trial name
- NCT04564599
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Methodist Health System
Shift-Work Sleep Disorder, Insomnia
Fire Fighter Fatigue Management Program: Operation Fight Fatigue
Firefighters frequently work extended duration shifts and long work weeks which have adverse effects on alertness, health, safety and performance.
- Conditions
- Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT01672502
- Testing
- Sleep health education provided via a web-based program, Sleep disorder detection and treatment, Optimization of Sleep in Fire Station
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Driving Under the Influence, Marijuana Intoxication
Cannabis Impairment Detection Application (CIDA)
Subjects will participate in a 4-visit study protocol in which they will be asked to complete a set of computerized tasks and a 45-minute simulated drive in a driving simulator.
- Conditions
- Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
- Trial name
- CIDA (NCT04230460)
- Testing
- Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Advanced Brain Monitoring, Inc.
Cognitive Impairment
Assess the Effect of Metaxalone 640 mg (M640) Compared to Tizanidine 8 mg on Truck Driving Ability and Cognition
Every participant will receive active study drug and one (1 )comparator, in two (2) stages, one after the other. Each drug will be taken one (1) time after a high fat meal.
- Trial name
- NCT06382662
- Testing
- metaxalone m640 mg, tizanidine 8mg
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Primus Pharmaceuticals
Impaired Driving
Video Feedback Intervention for Cognitively Impaired Older Drivers
This study will use an in-car monitoring system supplemented with video feedback to reduce the number of unsafe driving behaviors.
- Trial name
- NCT02600026
- Testing
- DriveCam, Feedback
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rhode Island Hospital
Cannabis Use, Driving Impaired
Neural Correlates of Driving and Cannabis
Driving is a set of complex tasks and requires use of multiple cognitive domains, including attention, planning, and memory. In laboratory studies, the main psychoactive component in cannabis, delta-9-tetrahydrocannabinol (THC)…
- Trial name
- NCT03581058
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Unity Health Toronto
Psychomotor Impairment
Sedative-Anxiolytic Effects on Simulated Driving Performance
This study evaluates the effect of anxiety drugs taken at night on the ability to drive a car the next day. Participants will receive alprazolam, placebo, or zolpidem at night before bed or in the morning before using a driving…
- Trial name
- NCT03297944
- Testing
- Alprazolam 2mg (2ALP/PLC), Alprazolam 1mg (1ALP/PLC), Alprazolam 0.5mg (0.5ALP/PLC)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marion Coe
Distracted Driving, Driving Impaired
Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders
Insurance User Based Insurance (UBI) users will be invited to participate in a randomized control trial where they will be randomized into 1 of 4 arms: (Arm 1) standard UBI, (Arm 2) Standard UBI + Free phone mounts (Arm 3)…
- Trial name
- NCT04587609
- Testing
- Free Phone Mounts, Commitment Contract, Personalized Habit Tips
- Where
- United States
- Volunteers
- 1,668 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alcohol Consumption
Vivitrol for Reducing Driving While Impaired Behavior Among Repeat Offenders
The purpose of this study is to determine whether Vivitrol is effective at reducing attempts to drive after drinking among repeat driving while intoxicated (DWI) offenders with Ignition Interlock devices.
- Trial name
- NCT00537745
- Testing
- Vivitrol (Medication Therapy), Medication Management Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Pacific Institute for Research and Evaluation
Stroke, Driving Impaired
Fitness to Drive Among Stroke Patients
The goal of this observational study is to learn more about who can continue driving a car after a stroke. The focus of this study is on the relationship between cognitive abilities and fitness-to-drive.
- Trial name
- NCT06111989
- Testing
- Neuropsychological testing, On road test
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- National Institute for Medical Rehabilitation, Hungary
Cognitive Measures, Driving Simulator Performance
Phenytoin and Driving Safety: A Randomized, Controlled Cross-Over Study
Automobile driving is a crucial aspect of everyday life, yet vehicular crashes represent a serious public health problem. Patients with epilepsy are at elevated risk for automobile crashes, causing great personal suffering and…
- Trial name
- NCT00581893
- Testing
- Phenytoin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Driving Under the Influence, Cannabis-impaired Driving
In-Vehicle Real-Time Cannabis Influenced Driving Detection
The goal of this clinical trial is to evaluate whether in-vehicle sensor data can be used to detect cannabis-impaired driving in healthy adult recreational cannabis users.
- Trial name
- REVELIO (NCT07401628)
- Testing
- Cannabis (THC)
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Bern
Impaired Driving
MedDrive's Responsiveness to Alcohol
This four-way, dose-response, crossover, double blind, placebo-controlled, randomised validation study investigates the responsiveness of MedDrive, a computed battery of neuropsychological tasks, to different doses of alcohol.
- Trial name
- OH-MedDrive (NCT01781273)
- Testing
- Ethanol, Cranberry juice
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Driving Behavior, Driving Under the Influence
Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSim
Subjects will participate in a 4-visit study protocol at the National Advanced Driving Simulator, part of the University of Iowa, in which they will be asked to complete assorted questionnaires, computerized cognitive tasks, and…
- Trial name
- PDID (NCT04970342)
- Testing
- 0.75 mg Alprazolam Capsule, Cannabis (6.18% THC / <0.025% CBD), Cannabis (0%/ THC / 0% CBD)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Timothy L. Brown
Driving Impaired, Alcohol Intoxication
Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests
The overarching aim of this study is to examine the impact of acute cannabis and alcohol administration on driving performance, as well as identify methods for detecting driving under the influence of these substances.
- Conditions
- Driving Impaired, Alcohol Intoxication, Driving Under the Influence, Cannabis Intoxication
- Trial name
- NCT05273658
- Testing
- Cannabis, Alcohol
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Drunk Driving, Alcohol Drinking
Design and Evaluation of an In-Vehicle Real-Time Drunk Driving Detection System
To analyze driving behavior of individuals under the influence of alcohol while driving in a real car. Based on the in-vehicle variables, the investigators aim at establishing algorithms capable of discriminating sober and drunk…
- Conditions
- Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT05796609)
- Testing
- Driving under the influence of alcohol
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Drug-impaired Driving
Oral Fluid Screening Devices
This research includes the evaluation of a checklist and on-site screening devices to pre-select drivers suspected of being drug-impaired.
- Trial name
- NCT00571207
- Testing
- On-site oral fluid screening devices, Checklist: drug recognition expert
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Marijuana Usage, Alcohol Drinking
Neuroscience of Alcohol and Marijuana Impaired Driving
Alcohol is one of the most widely used intoxicants. The effects of driving while intoxicated are well documented, leading to the laws and regulations behind drunk driving.
- Trial name
- NCT03431987
- Testing
- One day with a dose of active THC cannabis paired with alcohol
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Impaired Driving, Sleep Driving
Objective Assessment of the Effects of Shift Work on Drowsiness and Driving Impairment in Hospital Staff
The purpose of this protocol is to assess the risk of drowsy driving amongst shift workers using objective measures of drowsiness and driving performance in an instrumented research vehicle.
- Trial name
- NCT01672489
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Parkinson Disease, Driving Impaired
Using Advanced Driver Assistance Systems (ADAS) as an Intervention Strategy for Drivers With Parkinson's Disease
Parkinson's disease (PD) impacts an individual's fitness to drive in a number of ways that increase the crash risk in this population.
- Trial name
- NCT03195608
- Testing
- Lane change assistance system, Active Control
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Western University, Canada