Clinical trials: Drug Allergy
Peanut Allergy
Efficacy and Safety of Several Doses of Viaskin Peanut in Adults and Children With Peanut Allergy
The objectives of this dose-finding study for the treatment of peanut allergy are: To determine the efficacy of 3 doses of Viaskin Peanut (50 mcg ,100 mcg and 250 mcg peanut protein per patch) to significantly desensitize…
- Trial name
- VIPES (NCT01675882)
- Testing
- Viaskin Peanut 50 mcg, Viaskin Peanut 100 mcg, Viaskin Peanut 250 mcg
- Where
- 24 sites in United States, Canada and 3 more
- Volunteers
- 221 people
- Sponsor
- DBV Technologies
Asthma
Asthma Patient Survey Study to Assess Asthma Effect and Medication in Finland
This study was aimed at clarifying how the asthma medication is used in practice and how asthma affects everyday life. Total of 106 GPs were asked to recruit patients using inhaled steroid as maintenance treatment for asthma to…
- Trial name
- NCT00681382
- Volunteers
- 142 people
- Sponsor
- AstraZeneca
Asthma
Prospective Clinical Study on the Clinical Efficacy and Prognostic Outcome of ICS/LABA Combined With Liqin Zhike Formula in the Treatment of Cough Variant Asthma
To investigate the impact of the combination of ICS/LABA and Liqin Zhike Formula on the clinical efficacy and prognostic outcomes of cough variant asthma.
- Trial name
- NCT07272278
- Testing
- ICS+LABA, Chinese Medicine Formula
- Volunteers
- 236 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Tuberculosis, Multidrug-Resistant
Registry on the Effectiveness and Safety of the 9-month MDR-END Treatment Regimen in Korean Patients with FQ-sensitive MDR-TB (MDR-END Registry)
This study is to evaluate the effectiveness and safety of a 9-month MDR-END regimen as a treatment for fluoroquinolone-sensitive multidrug resistant pulmonary tuberculosis in the real-world clinical setting.
- Trial name
- NCT06674291
- Testing
- No intervention (observational study)
- Volunteers
- 222 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Atopic Dermatitis
The Efficacy of Patients With Moderate to Severe Atopic Dermatitis Treated With Chinese Herbal Medicine
Conduct a clinical trial of integration of Chinese and Western medicine to evaluate whether the association of traditional Chinese medicine therapy has a remission effect on atopic dermatitis, and to explore the remission of…
- Trial name
- NCT04686955
- Testing
- Xiao-Xian-Gui-Fu-Tang
- Where
- 2 sites in Taiwan
- Volunteers
- 19 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Hypertension
Using Multimedia Technology for Hypertension Control for Low-Income African Americans
The purpose of this study is to test an interactive DVD intervention to encourage patients to stick to their blood pressure medication in order to achieve blood pressure control for African American patients.
- Trial name
- CSI Birmingham (NCT00875225)
- Testing
- DVD, Intervention DVD
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cooper Green Mercy Hospital
Asthma
A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler (Puffer) in Adolescents and Adults Who Have Asthma That is Not Controlled by High Dose Inhaled Corticosteroid Asthma Medications
The primary objective of this study is to evaluate the dose response, efficacy and safety of 4 different doses of fluticasone propionate (50, 100, 200, and 400mcg) delivered as Fluticasone Spiromax® Inhalation Powder (Fp…
- Trial name
- NCT01576718
- Testing
- Fp MDPI, Flovent Diskus, albuterol/salbutamol
- Where
- 300 sites in United States, Australia and 17 more
- Volunteers
- 889 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Diabetes, Hypertension
Pharmacists Improving Refugees' Adherence and Knowledge of Their Chronic Medications
This study is a randomized, controlled, single-blinded clinical study which conducted over six months (May to October 2016) in different Jordanian cities, where most of Syrian refugees reside.
- Conditions
- Diabetes, Hypertension, Dyslipidemias, Cardiac Disease
- Trial name
- NCT04554810
- Testing
- Medication Management Service
- Volunteers
- 106 people
- Sponsor
- Prof. Iman Basheti
Solid Tumour
CIVO Intratumoural Microdosing of Anti-Cancer Therapies in Australia
This is a multi-center, open-label Phase 0 Master Protocol in Australia designed to study the localized pharmacodynamics (PD) of anti-cancer therapies within the tumour microenvironment (TME) when administered intratumourally in…
- Trial name
- NCT04891718
- Testing
- MVC-101, Nivolumab, MVC-101 + Nivolumab
- Where
- 3 sites in Australia
- Sponsor
- Presage Biosciences
Metastatic Castration-resistant Prostate Cancer
Efficacy and Safety of Organoid-Based Drug Sensitivity Screening to Guide the Treatment of mCRPC Patients Progressed After First-line Treatment
This observational study aims to learn about the effects and safety of organoid-based drug sensitivity screening in mCRPC patients with bone metastases that progressed after first-line treatment.
- Trial name
- NCT06529549
- Testing
- Organoid-Based Drug Sensitivity Screening
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sun Yat-sen University
Drug Hypersensitivity
Predictive Models for Betalactam Allergy
Background: ß-lactam (BL) antibiotics represent the main cause of allergic reactions to drugs, inducing both immediate and non-immediate reactions.
- Trial name
- NCT03076749
- Testing
- Creating models for the diagnosis of BL allergy
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Montpellier
Bronchial Asthma
Fasenra Pediatric Japan Post-Marketing Study(PMS)
The purpose of the investigation is to confirm the followings under the post-marketing actual use of Fasenra® Subcutaneous Injection 30 mg / 10mg Syringe (hereinafter referred to as Fasenra). 1.
- Trial name
- NCT06427876
- Where
- 9 sites in Japan
- Volunteers
- 40 people
- Sponsor
- AstraZeneca
Perennial Allergic Rhinitis
Efficacy and Safety of So-Cheong-Ryong-Tang on Perennial Allergic Rhinitis
The aim of this study is to investigate the short and long term efficacy and the safety of SCRT treatment for PAR
- Trial name
- NCT03009136
- Testing
- SCRT
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Peanut Hypersensitivity, Food Hypersensitivity
Peanut Epicutaneous Phase II Immunotherapy Clinical Trial
Food allergy occurs when the immune system reacts against foods. The immune system is the part of the body that protects us from illness and germs, but it can also cause allergies.
- Conditions
- Peanut Hypersensitivity, Food Hypersensitivity, Hypersensitivity, Hypersensitivity, Immediate
- Trial name
- NCT01904604
- Testing
- Low-dose DBV712 Viaskin® Patch, High-dose DBV712 Viaskin® Patch
- Where
- 5 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
To Decrease Dentin Hypersensitivity
Effectiveness of a Bonding and a Fluoride Varnish for Long-term Dentin Hypersensitivity Treatment.
Objectives: The aim of this in vivo randomized clinical trial with split-mouth design was to evaluate the clinical efficacy of one in-office application of a fluoride containing varnish and in office application of a bonding…
- Trial name
- NCT04813848
- Testing
- Application of varnish fluoride desensitizing agent on buccal surfaces of exposed dentin, Application of bonding agent desensitizing agent on buccal surfaces of exposed dentin
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- University of Roma La Sapienza
Asthma
A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants ≥ 18 Years of Age With Asthma
The goal of this study is to assess and compare the safety and tolerability of salbutamol administered via metered dose inhaler (MDI) containing propellant 1,1-difluoroethane (HFA-152a) or 1,1,1,2-tetrafluoroethane (HFA-134a) in…
- Trial name
- NCT06261957
- Testing
- Salbutamol HFA-134a, Salbutamol HFA-152a
- Where
- 102 sites in United States, Argentina and 11 more
- Volunteers
- 471 people
- Sponsor
- GlaxoSmithKline
Asthma
Influence Of Different Airflow Resistances On Drug Effect Of 50μg Salmeterol And 6 μg Formoterol
Effect of inhaled drugs administered as dry powder is not only dependent on drug efficacy but also on technical properties of the inhalers.
- Trial name
- NCT00327353
- Testing
- formoterol (TURBOHALER), Salmeterol (DISKUS)
- Where
- 2 sites in Germany
- Volunteers
- 77 people
- Sponsor
- GlaxoSmithKline
Asthma, Poor Medication Adherence
Multi-Component Technology Intervention for Minority Emerging Adults With Asthma
This pilot study's main goal is to develop and preliminarily test a technology-based intervention to improve asthma medication adherence in urban African American emerging adults (ages 18-29).
- Trial name
- NCT01714141
- Testing
- Multi-component, technology based intervention, Asthma education active control
- Volunteers
- 48 people
- Sponsor
- Wayne State University
Dry Skin, Sensitive Skin
A Clinical Study to Assess the Safety and Effectiveness of Test Product in Healthy Adult Human Subjects With Dry or Sensitive Skin
This exploratory, prospective, open-label, single-centre, safety, efficacy and in-use tolerability study of the test product in healthy adult human subjects with dry or sensitive skin.
- Trial name
- NCT06929988
- Testing
- Creanz Lotion
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- SAVA Healthcare Limited
Shellfish Allergy
Safety of Chitosan as Wine Fining Agent in Shrimp Allergic Patients
Chitosan, the main component of the exoskeletons of crustaceans, mollusks and cephalopods, has been used as a fining agent in wines. However, its safety among patients allergic to shellfish has never been evaluated.
- Trial name
- SWAP (NCT02151279)
- Testing
- Chitosan as wine fining agent, Control
- Where
- 2 sites in Portugal
- Volunteers
- 15 people
- Sponsor
- Universidade do Porto