Clinical trials: Drug Compliance
Tuberculosis, Drug-resistant Tuberculosis
An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment
This study is a U.S.-based, 1 site (with 4 clinical settings), randomized controlled trial (with funding from the Centers for Disease Control and Prevention's (CDC) Antibiotic Resistance Solutions Initiative) that will be…
- Conditions
- Tuberculosis, Drug-resistant Tuberculosis, Adherence, Medication, Adherence, Patient
- Trial name
- NCT03266003
- Testing
- Electronic DOT, In-person DOT
- Where
- 4 sites in United States
- Volunteers
- 216 people
- Sponsor
- Centers for Disease Control and Prevention
Pain, Postoperative, Medication Adherence
Evaluation of an Interactive Opioid Risk Education Program (STOMP) for Parents
Millions of children and adolescents are prescribed opioid pain relievers each year, placing them at risk for serious adverse events and misuse in the home setting.
- Conditions
- Pain, Postoperative, Medication Adherence, Opioid Use, Knowledge, Attitudes, Practice
- Trial name
- STOMP (NCT03287622)
- Testing
- Educational Intervention, Nudge
- Where
- United States
- Volunteers
- 712 people
- Sponsor
- University of Michigan
Hypertension (HTN), Blood Pressure
Team-Based Shared Decision-Making Program in Hypertension Control (Healthy Heart - BP Program)
The main goal of the study is to conduct a pilot trial to test the feasibility of the Team-Based Shared Decision-Making (SDM) Program, supported by Healthy Heart, involving 90 adults with uncontrolled hypertension (HTN) at…
- Trial name
- SDM in BP (NCT07909161)
- Testing
- Pharmacist-led Team-Based SDM on health behavior change and medication management for HTN control, Nurse-led Team-Based SDM on health behavior change and medication management for HTN control, Telehealth SDM visits focus on medication management and health behavior change
- Volunteers
- 90 people
- Sponsor
- Johns Hopkins University
Suicide, Suicidal Ideation
Telehealth to Reduce Suicidality and Improve HIV Care Engagement in Tanzania
The overall objectives of the proposed research are to develop a brief telehealth counseling intervention to provide support for people living with HIV and experiencing suicidal ideation, and to support HIV care engagement.
- Conditions
- Suicide, Suicidal Ideation, HIV Infections, Adherence, Medication
- Trial name
- NCT04696861
- Testing
- IDEAS for Hope, Enhanced Standard of Care (Safety Planning)
- Where
- 2 sites in Tanzania
- Volunteers
- 60 people
- Sponsor
- Duke University
Asthma
Comparing Asthma Action Plans for Pediatric Asthma
The purpose of this study is to evaluate and compare the relative effectiveness of two asthma action plans (pictorial versus written) in terms of asthma action plan knowledge, medication use, and family satisfaction with asthma…
- Trial name
- NCT00136305
- Testing
- Pictorial asthma action plan, Written asthma action plan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Children's Mercy Hospital Kansas City
Hypertension
Uncontrolled Hypertension Among the Homeless
This study is designed to assess the effect of implementing a mobile health (mHealth) strategy using text messaging for hypertension (HTN) management among hypertensive homeless persons with uncontrolled blood pressure age 21 or…
- Trial name
- NCT05187013
- Testing
- mHealth for Hypertension in Homeless Persons
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- George Washington University
Tuberculosis Active
Video-observed Therapy for Active Tuberculosis: a Feasibility Study
Tuberculosis (TB) is still present in Switzerland, and concerns mainly foreign-born subjects. Monitoring compliance to treatment by Directly Observed Therapy (DOT) is strongly encouraged by the World Health Organization (WHO).
- Trial name
- NCT06574529
- Testing
- Video-observed therapy (vDOT)
- Where
- Switzerland
- Volunteers
- 51 people
- Sponsor
- Ligue Pulmonaire Genevoise
Medication Adherence, Health Literacy
Minimizing Risk and Maximizing Outcomes in Geriatric Patients Through Integrated Clinical Pharmacy Services in an Innovative Model of Community Practice
It has been shown that patients can improve their safety through informed choice, safe medication use, and complication reporting.
- Conditions
- Medication Adherence, Health Literacy, Geriatric Patient Care Improvement, Pharmacy Economic Improvement
- Trial name
- NCT01351441
- Testing
- Medication adherence consultation, Medication problems assessment, Beer's Criteria Assessment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VascuScript Pharmacy
HIV Infections
A Study of Two Adherence Plans to Help HIV-Positive Patients Take Their Medications Correctly
The purpose of this study is to look at different ways to help patients follow their anti-HIV medication schedules. It is very important that HIV-positive patients take their anti-HIV medications correctly so they get the best…
- Trial name
- NCT00001129
- Testing
- Electronic Medication Reminder System, Medication Manager
- Where
- 20 sites in United States
- Volunteers
- 1,248 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chronic Migraine
Brief Interventions in Chronic Migraine
People with chronic migraine headaches face many challenges, including high levels of daily pain, disturbances to everyday activities and sleep, and problems with mood such as depression or anxiety.
- Trial name
- NCT05979337
- Testing
- Empowered Relief, Health Education (HE), Treatment as Usual
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Medication Adherence
Development and Evaluation of an Electronic Health Record-based Medication Complete Communication (EMC2) Strategy
There is a well-documented need for effective interventions that can help patients understand and safely adhere to prescribed medications, particularly those with greater potential for harm if not taken correctly.
- Trial name
- NCT03652272
- Testing
- EMC2
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Depression
Bright Start Study
The Bright Start study is a randomized trial to compare three approaches, or "arms", for delivering Bright Light Therapy (BLT) to real-world patients.
- Trial name
- NCT05356130
- Testing
- Written Educational Material on BLT, Enhanced BLT Encouragement and Adherence Promotion
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Kaiser Permanente
Breast Cancer Awareness
The Effect of Artificial Intelligence Chatbot and Expert Education on Breast Cancer Awareness Among Female Municipal Employees
This study compared two educational approaches for increasing breast cancer awareness among female employees of Eskisehir Odunpazari Municipality.
- Trial name
- NCT07749677
- Testing
- Artificial Intelligence Chatbot-Generated Educational Material, Expert-Developed Educational Material
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Rare Diseases, Fabry Disease
MigALastat Therapy Adherence Among FABRY Patients: A Prospective Multicentral Observational Study
This study evaluates adherence to the oral chaperone therapy migalastat in patients with Fabry disease.
- Conditions
- Rare Diseases, Fabry Disease, Adherence, Medication, Quality of Life
- Trial name
- MALTA-FABRY (NCT03683966)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Wuerzburg University Hospital
Medication Adherence
Electronic Medication Adherence Reporting and Feedback During Care Transitions
Patients often have problems with their medications after leaving the hospital and going back home. The goals of this study are to provide a special electronic pill-box with pre-filled weekly medication trays that can alert…
- Trial name
- NCT03475030
- Testing
- pre-filled medication trays, automated medication reminders
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Brigham and Women's Hospital
Schizophrenia, Bipolar Affective Disorder
Quality of Life, Safety and Compliance of Patients Using Monotherapy or Combinatorial Therapy With Quetiapine for Treatment of Schizophrenia or Bipolar Affective Disorder
The goal of this observational study is to evaluate the quality of life, drug safety and therapy compliance of schizophrenia or bipolar affective disorder patients during the treatment with quetiapine monotherapy or in…
- Trial name
- NCT07858565
- Testing
- Quetiapine (drug), quetiapine + aripiprazole, quetiapine + haloperidol
- Where
- Bosnia and Herzegovina
- Volunteers
- 500 people
- Sponsor
- Bosnalijek D.D
Adherence, Medication, Nonadherence, Medication
Interventions to Improve Specialty Medication Adherence
Patients deemed nonadherent to their specialty medications will be randomized to receive 8 months of patient-tailored adherence interventions and follow up from a specialty pharmacist as needed or the standard of care.
- Trial name
- NCT03709277
- Testing
- Pharmacist-Driven Intervention
- Where
- United States
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Hepatitis C, Liver Diseases
Improving Hepatitis C Treatment in Injection Drug Users
The overall goal of the research project is to improve the outcome of medical care for injection drug users (IDUs) with Hepatitis C viral (HCV) infection.
- Conditions
- Hepatitis C, Liver Diseases, Drug Abuse, Alcoholism
- Trial name
- NCT00148031
- Testing
- Pegylated Interferon and Ribavirin, Psychosocial, On-site (MMT Clinic) HCV evaluation and treatment
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- State University of New York - Upstate Medical University
Overweight, Childhood, Obesity Prevention
High Five! - School-based Prevention of Overweight and Obesity Among 6 to 9 Year Olds
The goal of this interventional study is to assess the effectiveness of the school-based "High Five!" program in reducing overweight, obesity and high blood pressure in children aged 7-9 years old.
- Conditions
- Overweight, Childhood, Obesity Prevention, Blood Pressure
- Trial name
- DINO-PL (NCT07357857)
- Testing
- High Five
- Where
- Poland
- Volunteers
- 659 people, healthy volunteers welcome
- Sponsor
- Institute of Mother and Child, Warsaw, Poland
Cardiovascular Diseases, Adherence, Medication
Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications
The study plans to learn if sending different text messages, serving as reminders or encouragement, may help patients take their medication more often if they have had trouble keeping up with their medicines.
- Conditions
- Cardiovascular Diseases, Adherence, Medication, Medication Adherence, Diabetes Mellitus
- Trial name
- NCT03973931
- Testing
- Nudge
- Where
- 4 sites in United States
- Volunteers
- 9,501 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
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