Clinical trials: Drug Compliance
HIV Infection
Use of Incentives to Retain Drug Users in HIV Therapy
In many urban centres including Vancouver's Downtown Eastside, there is a high rate of HIV infection among users of illicit drugs.
- Trial name
- Incentives-2 (NCT01488942)
- Testing
- monetary reinforcer
- Where
- Canada
- Volunteers
- 139 people
- Sponsor
- University of British Columbia
Osteoporosis
Evaluating Ways to Improve Medication Use Among People With Osteoporosis
Osteoporosis is a common bone disease in older adults in which the bones become weaker and prone to fracture. Medications are available to slow or even stop disease progression.
- Trial name
- NCT00567294
- Testing
- Mailed education, Telephone coaching program for patients, Medication adherence alert program for doctors
- Where
- United States
- Volunteers
- 2,087 people
- Sponsor
- Brigham and Women's Hospital
Dementia, Alzheimer's Disease and Related Dementias
HomeCare Medication Management for People With Dementia
This study will evaluate whether the HomeCare medication management system can improve medication adherence and related outcomes for adults age 65 and older living with dementia, Alzheimer's disease, or related dementias.
- Trial name
- NCT07872072
- Testing
- HomeCare
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- HiDO Technologies
Asthma, Medication Adherence
Structured Nursing Intervention for Adults With Poorly Controlled Asthma: A Pilot Study
Asthma affects a large number of adults, and many of them do not achieve good control of their symptoms. Poor inhaler technique, irregular medication use, and the lack of structured nursing follow-up are among the main reasons.
- Conditions
- Asthma, Medication Adherence, Self-management
- Trial name
- RESPiraIA (NCT07635537)
- Testing
- RESPiraIA-Asma
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital San Carlos, Madrid
Hypertension, Medication Adherence
Collabree: An Intervention to Improve the Regularity of Medication Intake
This a clinical study to improve medication adherence among patients with hypertension in Switzerland. Adult men and women who suffer from high blood pressure and have been prescribed a therapy consisting of at least 4 tablets…
- Trial name
- NCT04708756
- Testing
- Collabree Mobile Phone Application Medication Adherence Booster (simplified version), Collabree Mobile Phone Application Medication Adherence Booster
- Where
- Switzerland
- Volunteers
- 181 people
- Sponsor
- Collabree AG
HIV, Hypertension
INTEGRATE-RX: Integrating Clinical Pharmacists in HIV Care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden
The risk of heart attacks and stroke is two times higher among people living with HIV (PLWH), as compared to the general population.
- Conditions
- HIV, Hypertension, Cardiovascular Disease Prevention
- Trial name
- INTEGRATE-RX (NCT07711366)
- Testing
- INTEGRATE-RX
- Where
- 2 sites in Kenya
- Volunteers
- 450 people
- Sponsor
- Temple University
Heart Failure
Targeted Intervention to Improve Medication Adherence in Cognitively Impaired Patients With HF (TARGET)
Trialing an automated medication dispensing device (AMDD) to improve medication adherence in patients with heart failure.
- Trial name
- TARGET (NCT01602731)
- Testing
- Automated Medication Dispensing Device
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- VA Office of Research and Development
Polycystic Ovary Syndrome, Overweight
Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)
The purpose of this study is to determine the effects of stress reduction on glucose, blood pressure, quality of life and overall health and well-being in overweight or obese women, either with Polycystic Ovary Syndrome (PCOS) or…
- Conditions
- Polycystic Ovary Syndrome, Overweight, Obesity, Stress, Physiological
- Trial name
- NCT01464398
- Testing
- Stress reduction, Stress reduction with Health education
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Milton S. Hershey Medical Center
Multimorbidity, Polypharmacy
Multi-PAP: Improving Prescription in Primary Care Patients With Multimorbidity and Polypharmacy
This study assesses the effectiveness of a complex intervention in young-old patients with multimorbidity and polypharmacy aimed at improving physician drug prescription in primary care, measured by means of the Medication…
- Conditions
- Multimorbidity, Polypharmacy, Other Diagnoses, Comorbidities, and Complications
- Trial name
- Multi-PAP (NCT02866799)
- Testing
- Multi-PAP, Usual care
- Where
- 3 sites in Spain
- Volunteers
- 593 people
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Adherence, Medication, Chronic Disease
Efficacy of CareAide® App in Improving Adherence in Adults With Chronic Diseases
The goal of this clinical trial is to study the impact of a medication adherence app, CareAide, in adult population diagnosed with chronic diseases in Malaysian population. The main question[s] it aims to answer are: 1.
- Conditions
- Adherence, Medication, Chronic Disease, Quality of Life, Economic Burden
- Trial name
- CAREAide (NCT06068309)
- Testing
- CareAide App Usage
- Where
- 3 sites in Malaysia
- Volunteers
- 900 people
- Sponsor
- University of Malaya
Contraception
The Share Health Study: Teen Social Connections and Health
The purpose of this study is to determine whether delivery of SpeakOut, a behavioral intervention to increase social communication about long-acting reversible contraceptive (LARC) methods among adolescents, is associated with…
- Trial name
- NCT02791971
- Testing
- SpeakOut, Alcohol Control Intervention
- Where
- 2 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Aging, Fall Injury
Medication Empowerment and Deprescription for Safety (MEDS) Study
The long-term goal of this pragmatic, cluster randomized study is to develop a sustainable program for healthcare systems to reduce fatal and nonfatal falls among high-risk older adults living independently in their communities.
- Trial name
- MEDS (NCT04612166)
- Testing
- Medication Action Plan and Patient Empowerment (MAP-PE )
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of Iowa
Neoplasms Malignant, Surgery
Improved Adherence With Extended Venous Thromboembolism Prophylaxis After Major Cancer Surgery
This is a prospective, twin-center, cohort study in patients discharged from the hospital after major abdominal or pelvic cancer surgery for cancer.
- Conditions
- Neoplasms Malignant, Surgery, Venous Thromboembolism, Prophylaxis
- Trial name
- NCT04479579
- Testing
- Apixaban 2.5 milligram
- Where
- 2 sites in Canada
- Volunteers
- 53 people
- Sponsor
- McMaster University
Kidney Disease
SystemCHANGE: An Intervention for Medication Change in Adult Kidney Transplant Patients
With kidney transplant (KT) recipients as our exemplar population, our goal is to develop and test interventions that increase medication adherence (MA) in chronically ill adults.
- Trial name
- MAGIC (NCT02416479)
- Testing
- SystemCHANGE, Patient-education attention control
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Cynthia Russell
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Rate of Post-discharge Medication Adherence
Interactive Medication Reconciliation By Secure Messaging
Background and Significance: Adverse drug events (ADE) are the most common of all healthcare associated adverse events. Transitions between inpatient and ambulatory care can lead to ADE and avoidable healthcare utilization…
- Trial name
- SMMRT (NCT01564446)
- Testing
- Participants will receive a internet based secure message confirming adherence to post-discharge medication regimen
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- VA Boston Healthcare System
Medication Adherence
The eDosette Pilot Study
Medication non-adherence can lead to serious health issues for older adults. This study is a four week study in older adults using a new device, the eDosette, which dispenses and records how one takes their medications, and…
- Trial name
- NCT03513224
- Testing
- eDosette
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- McMaster University
Medication Adherence
Improvement in Medication Adherence Through the Implementation of Personalized Nudges: the ENCOURAGE Trial
This study will determine whether a complex, data-driven protocol for assessing patient needs and providing "nudges" (reminders to be adherent with medication prescriptions) improves adherence with cardiovascular medications.
- Trial name
- ENCOURAGE (NCT02490423)
- Testing
- Nudges Intervention
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Intermountain Health Care, Inc.
Pruritis, Hypotension Drug-Induced
Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia.
The purpose of this study is to investigate the effect of neuraxial analgesia initiation on the incidence of pruritus in laboring women.
- Conditions
- Pruritis, Hypotension Drug-Induced, Urinary Retention, Fetal Bradycardia During Labor
- Trial name
- NCT07187427
- Testing
- Spinal analgesia, Epidural Analgesia
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Justine's Hospital
Medication Adherence
Daily Delivery and Supervision of Psychotropic Medication for High-Risk Patients With Severe/Persistent Mental Illness
The main study intervention is the daily witnessing of participant self-administration of medications by trained pharmacy staff to ensure compliance.
- Trial name
- NCT03766503
- Testing
- Daily
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
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