Clinical trials: Drug Interaction Potentiation
Coronary Artery Disease, Drug Interaction Potentiation
Ranitidin Versus Omeprazole in Patients Taking Clopidogrel
Previous reports have shown a possible drug interaction between clopidogrel and proton pump inhibitors (PPI´s), which could result in increased number of adverse cardiovascular events among patients on dual antiplatelet…
- Trial name
- NCT01896557
- Testing
- omeprazole, Ranitidine, Clopidogrel
- Volunteers
- 92 people
- Sponsor
- University of Sao Paulo General Hospital
Drug Interaction Potentiation
Drug-drug Interaction Study in Healthy Male Volunteers Following the Administration of Pantoprazole and Rosuvastatin
This is a single-center, randomized, 2-period, 2-sequence, cross-over study.
- Trial name
- NCT01146483
- Testing
- Rosuvastatin, Pantoprazole
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Drug Interaction Potentiation
Drug-Drug Interactions of Grazoprevir/Elbasvir in Taiwan
Co-morbid diseases often present in a substantial proportion of patients with chronic hepatitis C (CHC) and require drugs to treat and control. Grazoprevir/elbavir is metabolized by cytochrome P-450 enzyme of liver.
- Trial name
- NCT03706222
- Testing
- elbasvir/grazoprevir
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Cheng-Kung University Hospital
Drug Interaction Potentiation
A Drug-Drug Interaction Study of Losartan and PA21
The purpose of this study is to determine if Losartan potassium is affected by PA21.
- Trial name
- NCT01324752
- Testing
- PA21 and Losartan with Food, No PA21; Losartan with food, PA21 with food and Losartan 2 hours later
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Vifor Pharma
Drug Interaction Potentiation
Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin
This is a Phase 1, two-part, open-label study to evaluate the interaction of cyclosporine, probenecid, and rifampin as perpetrators with vadadustat (victim) in healthy male and female subjects.
- Trial name
- NCT03801746
- Testing
- vadadustat, Rifampin, Probenecid
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Akebia Therapeutics
Healthy
A Drug-Drug Interaction Study of Furosemide and PA21
The purpose of this study is to determine if Furosemide is affected by PA21.
- Trial name
- NCT01438359
- Testing
- PA21 and Furosemide with food, No PA21; Furosemide with food, PA21 with food and Furosemide 2hrs later
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vifor Pharma
Medication Compliance, Drug-Related Side Effects and Adverse Reactions
Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial
Aim/Objective: Investigate the effect of implementing a working model for performing medication reconciliation (MR) and medication review (MRe) in the emergency department (ED), on readmissions, patient safety and efficiency of…
- Conditions
- Medication Compliance, Drug-Related Side Effects and Adverse Reactions, Remission, Medicinal Substance; Adverse Effect
- Trial name
- EPIMERR (NCT03123640)
- Testing
- Medication reconciliation and medication review
- Where
- Norway
- Volunteers
- 806 people
- Sponsor
- Diakonhjemmet Hospital
Drug Interaction Potentiation
A Drug-Drug Interaction Study of N91115 +/- Rifampin in Healthy Adult Subjects
The present study is designed to assess the effects of Rifampin on the pharmacokinetics of N91115 in healthy subjects.
- Trial name
- NCT02500667
- Testing
- N91115, Rifampin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nivalis Therapeutics, Inc.
Drug Interaction Potentiation
Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide
This is a Phase 1, open-label, 3-arm, fixed sequence, study to evaluate vadadustat as a perpetrator of drug-drug interactions (DDIs) with digoxin, adefovir and furosemide in healthy male and female subjects.
- Trial name
- NCT03801759
- Testing
- Vadadustat, Furosemide, Adefovir
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Akebia Therapeutics